Sevoflurane (txuas:https://www.bloomtechz.com/synthetic-chemical/api-researching-only/pure-sevoflurane-28523-86-6.html) yog ib hom tshuaj uas muaj cov tshuaj formula C4H3F7O, CAS 28523-86-6, thiab tus txheeb ze molecular mass ntawm 200.06 g/mol. Nws yog cov kua uas tsis muaj xim thiab pob tshab nrog lub qab zib tsis muaj zog ntawm chav sov. Nws yuav luag insoluble nyob rau hauv dej ntawm chav tsev kub, tab sis muaj zoo solubility nyob rau hauv ib co organic solvents, xws li ethanol thiab chloroform. Nws muaj lub siab vapor siab, ua rau nws yooj yim rau volatilize thiab nqus tau pa. Nws yog qhov ruaj khov ntawm chav tsev kub thiab tsis yooj yim rau decompose. Txawm li cas los xij, nyob rau hauv qhov kub thiab txias, xws li thaum tshav kub los ntawm qhov qhib nplaim taws, qhov kev puas tsuaj tuaj yeem tshwm sim. Nws muaj cov txiaj ntsig zoo biocompatibility thiab tshuaj loog, thiab siv dav hauv kev phais thiab kev kho mob. Sevoflurane belongs rau fluoroisopropyl ether chav kawm ntawm cov tshuaj thiab yog ib qho ntawm feem ntau siv halothane tshuaj loog.
Sevoflurane (Sevoflurane) yog ib qho tshuaj loog uas muaj ntau yam siv tshuaj.
1. Cov kuab tshuaj:
Sevoflurane yog cov kua uas tsis muaj xim, tsis muaj ntxhiab tsw uas muaj qhov kub kub. Vim nws cov solubility zoo thiab tsis tshua muaj toxicity, Sevoflurane tuaj yeem siv los ua cov kuab tshuaj hauv qee qhov chaw kuaj thiab chaw ua haujlwm. Piv txwv li, nws tuaj yeem siv los ua qhov nruab nrab cov tshuaj tiv thaiv rau cov tshuaj inorganic thiab cov organic sib txuas, pab kom ua tiav cov tshuaj tiv thaiv.
2. Amplifier:
Sevoflurane tau siv los ua qhov nthuav dav hauv roj chromatography (GC) hauv qee qhov kev tshawb fawb. Vim nws cov tshuaj lom neeg ruaj khov thiab tsim nyog volatility, Sevoflurane tuaj yeem siv los txhim kho qhov rhiab heev ntawm kev sib cais thiab kev kuaj xyuas. Daim ntawv thov no ua rau Sevoflurane nyiam mloog hauv kev saib xyuas ib puag ncig, kuaj zaub mov thiab tshuaj xyuas tshuaj.
3. Txheej khoom:
Sevoflurane tuaj yeem siv los ua ib qho ntawm cov khoom siv txheej txheej, uas tuaj yeem ua haujlwm tshwj xeeb hauv qee qhov kev siv. Piv txwv li, Sevoflurane ua ke nrog cov tshuab polymer tuaj yeem siv los npaj cov ntaub ntawv nrog cov khoom tshwj xeeb, xws li deg wettability, biocompatibility, thiab lwm yam.
4. Cov ntxhiab tsw:
Vim tsis muaj ntxhiab tsw ntawm Sevoflurane, nws yog siv los ua tshuaj tsw qab hauv qee yam khoom. Piv txwv li, hauv cov tshuaj tsw qab thiab cov khoom tu tus kheej, ntxiv ib qho me me ntawm Sevoflurane tuaj yeem npog qhov tsw ntawm lwm cov khoom xyaw thiab txhim kho cov aroma ntawm cov khoom.
5. Gas ntes:
Vim nws qhov kub tsis tshua muaj vaporization thiab siab vapor siab, Sevoflurane tuaj yeem siv rau calibration thiab kuaj cov roj detectors. Hauv kev tshawb nrhiav roj, Sevoflurane tuaj yeem siv los ua cov qauv roj rau kev ntsuas kom ntseeg tau qhov tseeb thiab kev ntseeg siab ntawm cov cuab yeej kuaj roj.
6. LCD zaub:
Sevoflurane tau pom los ua lub luag haujlwm hauv kev tsim cov kua siv lead ua kua. Nws tuaj yeem siv los ua tus stabilizer thiab polarity changer rau cov kua siv lead ua kua molecules, pab txhim kho kev ua tau zoo thiab zoo ntawm cov kua siv lead ua kua.
7. Tus neeg saib xyuas tu:
Sevoflurane lub cev thiab tshuaj lom neeg ua rau nws muaj peev xwm muaj peev xwm nyob hauv qee cov tshuaj ntxuav. Qee zaum, Sevoflurane tuaj yeem siv los ua cov kuab tshuaj organic los pab tshem tawm stains thiab deposits.
8. Kab tshuaj tua kab:
Qee qhov kev tshawb fawb tau pom tias Sevoflurane muaj kev ua haujlwm tawm tsam yoov tshaj cum. Yog li ntawd, nws yog tshawb nrhiav rau kev npaj cov tshuaj yoov tshaj cum los yog tshuaj tiv thaiv yoov tshaj cum. Txawm li cas los xij, daim ntawv thov no tseem nyob rau theem kev tshawb fawb thaum ntxov, thiab xav tau kev tshawb fawb ntxiv los ntsuas nws qhov ua tau zoo thiab ua tau.
9. Reactants nyob rau hauv cov tshuaj tiv thaiv:
Sevoflurane tuaj yeem siv los ua cov tshuaj reactant hauv qee cov organic synthesis tshuaj. Piv txwv li, Sevoflurane tuaj yeem koom nrog hauv cov tshuaj tiv thaiv xws li epoxidation thiab hydrogenation, muab cov txheej txheem hluavtaws tshiab thiab cov tswv yim rau cov organic chemical synthesis.
10. Synthesis ntawm cov tshuaj zoo:
Qhov zoo fluorinated ntawm Sevoflurane ua rau nws muaj txiaj ntsig zoo hauv kev tsim cov tshuaj zoo. Raws li cov tshuaj fluorine-muaj cov khoom xyaw, Sevoflurane tuaj yeem siv rau hauv cov organic synthesis tshwm sim hauv qee qhov tshwj xeeb los qhia txog cov tshuaj fluorine atoms lossis hloov cov qauv spatial ntawm molecules.
11. Kev tsim khoom siv hluav taws xob:
Vim nws cov purity siab thiab physicochemical zog, Sevoflurane yog siv nyob rau hauv cov txheej txheem tsim khoom ntawm ib co electronics. Piv txwv li, hauv kev lag luam semiconductor, Sevoflurane tuaj yeem siv los ua cov roj rau kev ntxuav thiab npaj cov chaw.
Hais txog lub npe keeb kwm ntawm Sevoflurane, ntawm no yog qee qhov tseem ceeb tshaj plaws:
1. Kev Tshawb Fawb: Sevoflurane tau pom thawj zaug los ntawm xibfwb Ei-Ichi Negishi thiab lwm tus hauv Nyij Pooj thaum xyoo 1970s. Lawv tshawb pom Sevoflurane thaum lawv tshawb fawb txog cov tshuaj fluoroisopropyl thiab pom tau tias nws yuav muaj peev xwm ua rau muaj kev phom sij.
2. Nomenclature: Sevoflurane tau ua lag luam thawj zaug hauv xyoo 1975 thiab tau hu ua "Sevoflurane" los ntawm Abbott Laboratories, lub npe uas tuaj yeem taug qab nws cov qauv tshuaj. "Sevo" txhais tau tias nws los ntawm "ntau yam" thiab "flurane" txhais tau tias nws yog tshuaj fluoroisopropyl ether.
3. Kev pom zoo thiab nce qib: Hauv xyoo 1980s, Sevoflurane tau pib siv dav hauv kev kho mob. Xyoo 1994, US Food and Drug Administration (FDA) tau pom zoo Sevoflurane ua tshuaj loog, thiab tsis ntev nws tau pom zoo thiab lees paub los ntawm ntau lub tebchaws.
4. Kev lag luam cuam tshuam: Sevoflurane tau dhau los ua ib qho tshuaj loog uas siv ntau tshaj plaws hauv ntiaj teb thiab tau siv dav hauv kev ua haujlwm tshuaj loog hauv chav ua haujlwm. Nws qhov zoo muaj xws li induction thiab rov qab sai, kho qhov tob ntawm cov tshuaj loog, tsis tshua muaj roj coefficient, thiab zoo physiological compatibility.
Feem ntau, Sevoflurane muaj npe tom qab nws cov qauv tshuaj thiab cov txheej txheem kev lag luam. Nws qhov kev tshawb pom thiab nws daim ntawv thov kev kho mob tau zoo ua rau nws yog ib qho ntawm cov tshuaj loog uas siv ntau tshaj plaws niaj hnub no.