Gaba ntshiab hmoov li 56-12-2

Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov khoom lag luam Gaba ntshiab li 56-12-2 hauv Suav teb. Txais tos rau kev lag luam wholesale loj zoo Gaba cov hmoov ntshiab uas 56-12-2 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.

Gaba ntshiab hmoov, Alias ​​4 {{{{{7} inechutyric acid (gaba). Nws yog dawb siv lead ua hmoov thiab ua gaba hmoov. Nws tsis muaj kev ua haujlwm kho qhov muag thiab yog tus ua txhaum nrog dej. Nws yog me ntsis soluble hauv ethanol thiab acetone, tab sis insoluble nyob rau hauv benzene thiab ether. Nws yuav poob dej thaum lub sijhawm disomposition los tsim pyrrolidone. Nws yog cov amino acids thiab dav hauv vertebrates, nroj tsuag thiab cov kab mob me me} Kuv muaj cov dej ua kom zoo thiab cov dej khov kho kom ruaj khov thiab thermal stability. Nws tau raug lees tias Gaba, raws li ib tug me me molecular hnyav tsis-protein amino acids, muaj kev nyab xeeb thiab tuaj yeem siv rau hauv cov dej haus thiab lwm yam zaub mov noj. Cov kev tshawb fawb tau pom tias qee qhov nyiaj ntawm Gaba tuaj yeem txhim kho lub cev pw tsaug zog zoo thiab txo cov ntshav siab.

Gaba ntshiab hmoov(Gaba) yog ib qho tshwm sim tsis muaj protein amino acid dav faib hauv microbial, nroj tsuag, thiab tsiaj txhu cov ntaub so ntswg neural. Raws li qhov tseem ceeb inibitory Neurotransmitter ntawm nruab nrab lub paj hlwb, Gaba ua si lub luag haujlwm tseem ceeb hauv kev nplij siab, kev ntxhov siab los ntawm kev tswj hwm cov ntshav neuronal.

Kev teb Medical: Cov tub ntxhais tseem ceeb ntawm kev tswj hwm neural thiab kev kho mob kab mob

 

1. Kev kho mob ntawm neurological tsis zoo
Anti ntxhov siab thiab kev ua kom muaj zog: los ua kom ua kom zoo nkauj rau inhibit neuronat ntau dhau, txo cov kev ua si tsis zoo, thiab ua ib lub hlwb ua kom pom tseeb. Clinically, nws feem ntau siv rau kev ntxhov siab ntxhov siab, tsis tsaug zog, thiab tshee nrhav. Piv txwv li, thaum ua ke nrog tshuaj tiv thaiv tshuaj, nws tuaj yeem txhim kho kev ua tau zoo thiab txo cov tshuaj muaj kev pheej hmoo ntawm.
Kev kho mob Epilepy: raws li ib tug inibitory neurotransransmitter nyob rau hauv lub hlwb, nws tuaj yeem thaiv kev kis tus qaug dab peg ntawm cov neeg qaug zog ntawm epileptic. Kev tshawb fawb tau pom tias ntxiv Gaba lossis txhawb nws cov synthesis (xws li dhau los ntawm glutamate decaramelase) tuaj yeem txhim kho cov tsos mob hauv cov neeg mob mob mob Epileps.
Neurodegeneritive kab mob txawj kab mob Piv txwv li, nws tuaj yeem ua rau muaj kev zoo siab ntau dhau ntawm dopamininer kev neurons thiab tiv thaiv kev ua haujlwm ntawm lub cev nigrostriatal.

 

2. Kev cuam tshuam rau cov kab mob metabolic
HypoglyCemic nyhuv: los ntawm kev txhawb nqa kev hloov pauv ntawm pancreatic alpha hlwb cia, thiab txo cov tshuaj insulin, nws tswj cov ntshav zoo li ntshav. Cov kev sim tsiaj tau qhia tias kev tswj hwm Gaba mus rau hyperglycemic tsuag muaj txo lawv cov ntshav qab zib txo qis, nrog kev cuam tshuam zoo dua li metformin.
Antihyperensive mechanism: los ntawm kev ua kom cov ntshav siab, nws txoj kev ntawm cov kab mob caj pas Cov kev tshawb fawb soj ntsuam tau pom tias tom qab noj Gaba cov khoom lag luam rau 4 lub lis piam, cov neeg mob siab tshaj plaws muaj ntshav nce siab.

 

3. Kev tiv thaiv ntawm daim siab thiab raum ua haujlwm
Hepatoprotrotective nyhuv: nws tuaj yeem ua kom lub siab gaba - qhov kev ntxhov siab thiab txo lub siab ua rau cov tshuaj lom fluoride thiab ethanol. Piv txwv li, hauv Ethanol ua rau daim siab raug mob, ntshav almanine aminotransferase (alt) qib tau txo qis los ntawm kev txhim kho lub siab hom qauv thiab txo cov nqaij tawv nqaij.
Lub raum tiv kev puas tsuaj: los ntawm kev tswj hwm ntawm lub raum hemodynamics, txhim kho Sodium excretion muaj nuj nqi, thiab uncutiating mob raum raug mob. Kev tshawb fawb tau pom tias nws tuaj yeem txo tus naj npawb tunel zoo hauv cov pob txha ntawm cov nas uas muaj cov ntshav tsim kho cov tsiaj txhu.

 

4. Kev kho mob uas txiav txim siab
Kev kho kom zoo ntawm Post - stroke streamose syntheles: los ntawm kev txhim kho lub hlwb thiab kev txhim kho hlwb thiab kev txhim kho cov lus thiab kev ua haujlwm lub cev.
Kev kho mob ntawm hepatic encephay: raws li ib qib twg uas muaj kev tiv thaiv kab mob siab, inhibit glutamate cov tshuaj tiv thaiv, thiab txo cov tsos mob neurotoxic.

Cov Khoom Noj Khoom Noj: Cov Carrier tshiab rau kev ua haujlwm txhim kho thiab kev hloov kho khoom noj khoom haus

 

1. Cov zaub mov ntxiv
Qab Enhancer:Gaba ntshiab hmoovMuaj ib lub ntuj qaub saj thiab tuaj yeem hloov qee cov tshuaj ntxiv kom txhim kho cov khoom noj tshiab. Piv txwv li, ntxiv gaba rau fermented cov kua taum yuav ua kom lawv umami index los ntawm ntau dua 30%.
Moisturizing cov neeg sawv cev thiab stabilizers: lawv cov kev hygroscopicity tuaj yeem tiv thaiv cov zaub mov ntawm kev ziab thiab txhaws, txuas lub neej. Ntxiv 0.1% -0.3% Gaba rau cov khoom ci ci tuaj yeem ua kom cov dej noo raint ntawm cov mov ci los ntawm 15% -20%.
Cov khoom noj muaj txiaj ntsig zoo: Ua cov zaub mov muaj tshiab, lawv raug tso cai ntxiv rau kev haus, khoom noj siv mis, thiab cov khoom noj muaj haujlwm. Piv txwv li, germinated xim av nplej nplua nuj nyob rau hauv Gaba tuaj yeem txo cov ntshav ntshav qab zib muaj peev xwm ua rau cov neeg mob hom 2 yam mob ntshav qab zib.

 

2. Kev loj hlob ntawm cov zaub mov ua haujlwm
Cov Zaub Mov Noj: Los tswj kev sib npaug ntawm Gamma Aminobutyric Acid / glutamate, nws luv lub sij hawm kom tsaug zog thiab ntev kev sib sib zog nqus lub voj voog. Gaba Gummies, tshuaj yej dej haus, thiab lwm yam khoom ntawm kev ua lag luam feem ntau muaj ib qho koob tshuaj ntawm 100-300 mg, uas tuaj yeem txhim kho kev pw tsaug zog los ntawm 20% -30%.
Anti Lwj Zaub Mov: nws qeeb qhov tshwm sim ntawm kev tawm dag zog -}} ibermiting qhov kev xa tawm ntawm kev xa tawm ntawm kev ua haujlwm hauv nruab nrog. Tom qab ncaws pob ntxiv Gaba, lub sijhawm tshaj plaws ua ntu zus yog 12%, thiab cov ntshav daws teeb meem ntshav ntxiv nce li 25%.
Cov menyuam yaus kev loj hlob ntawm cov menyuam yaus: los ntawm kev txhawb nqa lub zais cia ntawm kev loj hlob muaj, nws pab rau hauv kev txhim kho kom zoo ntawm cov neeg hluas. Cov ntaub ntawv kuaj mob qhia tau tias cov menyuam yaus uas pab ntxiv nrog 50 mg gaba txhua hnub kev nce siab nyob rau hauv siab ntawm 1.2-1.8 cm piv rau pawg tswj.

Cov qauv ntsuab rau cov qoob loo ntxhov siab thiab kev txhim kho kom zoo dua qub hauv kev ua lag luam

 

1. Cog Kev Loj Hlob Regulators
Txhim Kho Kev Nyuaj Siab Ua Haujlwm: Los ua kom cov nroj tsuag antioxidant enzyme system, cov qoob loo tuaj yeem txhim kho lawv txoj kev ua kom poob, salinity, thiab dej kub tsawg. Piv txwv li, txau 10-20 mg / u gaba tov thaum lub sij hawm nplej nplej tuaj yeem ua kom muaj zog ntau los ntawm 8% thiab txhim kho chaw nyob ntawm 30%.
Tos nce: nws txhawb nqa cov txiv hmab txiv ntoo ua los ntawm kev tswj cov ntawv faib ntawm cov khoom lag luam phopinthetic. Txau gaba thaum lub sij hawm lws suav tuaj yeem nce ib leeg txiv hmab txiv ntoo muaj zog los ntawm 15% -20% thiab vitamin C cov ntsiab lus los ntawm 25%.

 

2. Pub tshuaj ntxiv
Cov tsiaj txhu thiab cov nqaij qaib loj hlob kev nce qib: los ntawm kev txhim kho qhov sib npaug ntawm cov plab me microbiota thiab nce siab pub rau kev pub hloov dua siab tshiab. Ntxiv 2-4 g / kg gaba rau broiler pub tuaj yeem nce txhua hnub txhua hnub nce los ntawm 10% -15% thiab txo qis rau cov nqaij piv rau 0.2-0.3.
Nqaij ua tau zoo dua qub: nws txo cov roj ua tuab ntawm cov tsiaj txhu thiab nqaij qaib los ntawm kev nthuav qhia cov noob muaj feem cuam tshuam txog cov khoom siv rog rog. Piv txwv li, ntxiv gaba rau cov pub ntawm fattening npua tuaj yeem txo cov backfat tuab los ntawm 0.5-1.0 cm thiab nce leeg marble tau los ntawm 1-2 qib.

Kev Siv Cov Ntawv Siv: Kev tawg tshiab nyob rau hauv cov khoom siv hluavtaws thiab biocatalysis

 

1. Biovater Primite
Synthesis ntawm nylon-4:Gaba ntshiab hmoovYog ib qho tseem ceeb monomer rau kev npaj biodegradable nylon-4, uas tsim cov khoom siv polymer polymer los ntawm kev siv tshuaj kho mob thiab ib puag ncig kev phooj ywg.
Peptide thiab protein synthesis: uas yog cov khoom siv raw rau cov tshuaj amino acid, thiab cov khoom siv garuthatione thiab coenzyyme a, thiab muaj tus nqi tseem ceeb hauv kev tsim cov tshuaj hauv tsev.

 

2. Green Chemistry Cataly
Microbial Fermentation ntau lawm: siv microbial fermentation txoj kev xws li lactic acid bacteria thiab poov xab los tsim Gaba muaj qhov zoo ntawm tus nqi qis thiab kev nyab xeeb. Piv txwv li, los ntawm kev txhim kho cov txheej txheem fermentation ntawm lactic acid bacteria, cov tawm los ntawm gaba tuaj yeem ncav cuag ntau dua 50 g / l, ntsib cov kev thov.
Tag nrho cov xovtooj ntawm tes ntawm catalysis muaj: immobilizing Gaba synthease nyob rau saum npoo ntawm cell membrane kom ua tiav ntau lawm. Cov thev naus laus zis no tuaj yeem nce cov tshuaj tiv thaiv hloov pauv tau ua tau zoo rau ntau tshaj 95% thiab cuam tshuam ntau dua li kev siv hluav taws xob.

Cov Tshuaj Pleev Teb Teb: Cov thev naus laus zis ntawm anti -}} kev kho mob thiab kev tiv thaiv tawv nqaij

 

1. Anti Laus Mechanism
Collagen Synthesis nce qib: Gaba nce collagen qhia los ntawm kev ua kom lub tgf - kev rau txim txoj hauv kev hauv fibraiglasts. Qhov kev sim uas muaj hais tias lub ntsiab muaj 2% GABA tuaj yeem nce cov tawv tawv ywjlculus los ntawm 18% -22%.
Dawb radical lom zem: nws inhibits lipid peroxidation los ntawm chelating hlau ions. Nyob rau hauv dpph radical scavennging kev sim, IC50 tus nqi ntawm Gaba yog 0.8 mg / ml, qhia tau zoo antioxidant muaj peev xwm rau vitamin C.

 

2. Kev kho kom tawv nqaij
Txo cov dej sib nraus sib hloov Cov kev kuaj mob kho mob tau pom tias tom qab 4 lub lis piam ntawm kev siv cov cream tas los ntawm 1% GABA, tus nqi TEWL txo li 25% -30%.
Anti inflammatory effect: nws txo UV txwv tsis pub tawv nqaij los ntawm kev txwv tsis pub muaj NF {{} {κ b qha rau txoj kev. Nyob rau hauv cov qauv tsiaj, Gaba tuaj yeem txo cov index erthema los ntawm 40% -50%.

Xyoo 1993, qee cov kws tshawb fawb ntse tsim Gaba los ntawm tshuaj lom neeg synthesis thawj zaug. Tom qab ntawd, kev tshawb fawb muaj feem xyuam tau dhau los ua kev nplua nuj zuj zus. Txhawm rau kom tau txais ntau GABA, cov kws tshawb nrhiav tau pib ntau yam kev sim thiab tau txais ntau qhov ua tiav.

1. Tshuaj lom neeg hluavtaws hluavtaws:

Tseem ceeb tshuaj synthesis tsuas yog suav nrog cov hauv qab no:

Qhov thib ib yog siv cov poov xab pthalate thiab - yog cov khoom siv raw thiab butyrolysze muaj kev kub ntxhov thiab hydrolyze kom tau txais Gaba ua cov khoom kawg;

Qhov thib ob yog siv pyrrolidone raws li thawj cov khoom siv recium hydroxide thiab ammonium bicarbonate, thiab thaum kawg qhib lub nplhaib kom tau txais Gaba;

Qhov thib peb yog siv butyric acid thiab cov ammonia li cov ntaub ntawv raw ntawm gaba, yog li ntawd Gaba tau txais los ntawm lub teeb tshuaj tiv thaiv nyob rau hauv x {{ray mob mob;

Tus qauv thib plaub yog los ua keGaba ntshiab hmoovlos ntawm glow tawm nrog cov tswv yim thiab formic acid;

Thib tsib yog cov methyl bromooacetate thiab ethylene yog siv los npaj gaba, me me cov khoom lag luam yog gaba tom qab amoos hlwb thiab hydrolysis. Cov tshuaj antthesis txoj kev ntawm Gaba muaj qhov tsis zoo ntawm kev tswj tsis muaj kev tswj hwm tsis muaj kev tswj hwm thiab tus nqi siab.

2. Cog cov qauv txheej txheem:

Tus txheej txheem cog qib ntxiv yog qhov tshiab tsim hluavtaws cov ntsiab lus thev naus laus zis, uas siv cov nroj tsuag muaj kev sib cais thiab cov khoom lag luam pheej yig thiab siab purity gaba khoom. Muaj ob txoj kev tseem ceeb kom tau txais Gaba los ntawm cov nroj tsuag: ib qho yog cov kuab tshuaj ntxiv thiab ua kom huv thiab kev npaj sab nrauv thiab npaj.

(1) cov kuab kev teeb meem extraction

Txoj kev daws teeb meem rho tawm cov dej los yog dej cawv ua cov extractant ntawm Gaba. Raws li lub hauv paus ntsiab lus ntawm cov nroj tsuag sib txawv hauv dej lossis dej cawv thiab xa rov qab coeffation thiab kev ntxuav tawm, feem ntau ntawm Gaba hauv cov nroj tsuag tuaj yeem muab rho tawm.

(2) Kem sib cais npaj txoj kev

Kev sib cais cov txheej txheem, tseem hu ua kem chromatography, yog ib txoj kev ntawm cov haujlwm kom sib xyaw ua ke muaj kev faib tawm cov coefficients sib txawv hauv cov theem thiab kua theem. Nws cov kev faib tawm dav dav yuav tsum tau ntaus nqi rau cov chromatography. Feem ntau, cob, silica gel lossis ua kom cov pa roj carbon ntau siv los sau cov ntaub ntawv rau cov chromatographic txhua.

3. Microbial fermentation:

Microbial Fermentation txoj kev yog los npaj thiab tsim Gaba los ntawm kev xaiv zoo, ruaj khov, tsis yog} cov leeg muaj kev phom sij hauv cov txheej txheem ntawm cov txheej txheem ntawm kev loj hlob thiab luam. Txawm hais tias txoj kev no muaj qhov yuav tsum tau ua rau ib puag ncig thiab khoom siv, tus Gaba ua los ntawm hom qauv no tuaj yeem siv los ua khoom noj khoom haus tsiaj qus ntxiv. Microbial fermentation yog ib qho ntawm qhov ntxov thiab feem ntau cov qauv siv ntau yam hauv kev lag luam khoom noj. Thawj cov kab mob sib kis tau siv yog escherichia coli, uas nws decarboxylase tuaj yeem siv los tsim Gaba. Txawm li cas los xij, vim nws tus kheej kev ruaj ntseg kev ruaj ntseg, nws tau tsis muaj peev xwm siv tau ncaj qha rau hauv kev tsim cov tshuaj lossis khoom noj.

Nrog rau kev txhim kho kev tshawb fawb thiab thev naus laus zis, tib neeg them nyiaj ntau thiab ntau dua rau cov zaub mov ntsuab. Tom qab ntawd, cov kws tshawb nrhiav pom tias cov kab mob acids, poov xab, aspergillus thiab lwm yam microcherics tuaj yeem siv los hloov Escherichia coli mus rau catchericy cataling ntau lawm ntawm gaba. Ntxiv mus, nyob rau hauv cov xwm txheej ntawm tus nqi qis, nws muaj qhov zoo ntawm cov zis siab siab thiab kev nyab xeeb zoo, thiab cov qauv no tau tsim kho kom tiav.

-} inekuyric acid alias {{{} inechutyric acid (- aminobutyric acid (Gaba ntshiab hmoovRau luv luv) yog amino acid, Tshuaj mis: H2Nch2ch2Cooh; Molecular hnyav: 103.1. Gaba yog cov hmoov dawb crystalline tsis muaj kev ua haujlwm. Lub taw tes melting yog 195-204℃(decomposition), uas yog miscomged nrog dej, me ntsis soluble hauv ethanol thiab acetone, thiab insoluble nyob rau hauv benzene thiab ether. Thaum lub sij hawm decomposition, dej yuav ploj mus tsim pyrrolidone.

Gaba feem ntau muaj nyob rau hauv kev daws nyob rau hauv daim ntawv ntawm cov form ntawm zwitterion (tsis zoo them cov pab pawg carboxyl thiab pab pawg zoo tshaj). Vim kev sib cuam tshuam electrostatic nyob nruab nrab ntawm cov pab pawg zoo thiab tsis zoo tau txais ob pawg Txawm li cas los xij, qhov sib xws ntawm ntau txoj kev sib xyaw ua ke nrog kev daws teeb meem rau ntau yam receptor protein thiab ua ntau lub dag zog ua haujlwm.

Cim npe nrov: Gaba ntshiab hmoov uas 56-12-2, cov neeg xa khoom, chaw tsim khoom, Hoobkas, lag luam Wholesale, yuav, nqe, loj, loj, rau muag