Triphamenyl phosphate(TPP) yog cov tshuaj sib txuas nrog cov mis (C6h5o) 3p. Nws yog ib qho tsis muaj kob rau dawb crystalline khoom nrog qhov txawv ntxhiab tsw. TPP feem ntau yog siv los ua nplaim taws retardant, yas, thiab addards cov khoom lag luam thiab muaj peev xwm txhim kho cov ntaub ntawv.
Hauv thaj teb ntawm cov nplaim hluav taws retardants, TPP tau ua haujlwm nyob rau hauv cov polyestant, epoxies, thiab lwm cov ntaub ntawv polymies, thiab lwm cov ntaub ntawv polymeric los txhim kho lawv txoj kev tawm tsam kom tiv thaiv thiab txuas ntxiv. Nws ua haujlwm los ntawm kev tso tawm phosphorus-muaj radicals thaum cuam tshuam nrog txoj saw kev sib tw uas muaj hluav taws kub.
Raws li lub tshuab yas, TPP tuaj yeem txhim kho qhov hloov tau thiab elongation ntawm cov plastics, ua rau lawv haum ntau rau cov kev siv cov kev sib tw uas muaj kev sib cav. Txawm li cas los xij, nws siv raws li lub tshuab yas tau poob qis me ntsis vim muaj kev txhawj xeeb txog nws qhov kev cuam tshuam ib puag ncig thiab muaj kev lom zem ib puag ncig.
TPP tseem siv los ua kev ntxiv nyob rau hauv cov roj nplua nyeem, cov kua dej hydraulic, thiab lwm yam kua muaj los txhim kho lawv cov khoom ua tau zoo. Ib qho ntxiv, nws pom cov ntawv thov nyob rau hauv synthesis ntawm lwm yam tshuaj lom neeg thiab raws li kev sib txuas hauv kev tsim cov tshuaj thiab dyes.
Txawm hais tias nws cov khoom muaj txiaj ntsig, TPP tau tsa cov kev txhawj xeeb txog nws txoj kev pheej ib puag ncig thiab muaj kev lom zem rau dej hiav txwv. Raws li qhov kev tshawb fawb, kev tshawb fawb yog kev txuas mus ntxiv los tsim kho cov nplaim hluav taws xob retardants thiab cov hnab yas uas muaj cov profiles ib puag ncig. Txawm li cas los xij, TPp tseem yog ib qho kev ua haujlwm tseem ceeb hauv ntau cov kev lag luam vim nws cov khoom sib xyaw ua ke ntawm cov khoom thiab versatility hauv kev thov.
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Tshuaj Cov Qauv |
C18H15O4P |
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Muaj pes tsawg leej |
326.07 |
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Molecular hnyav |
326.29 |
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m/z |
326.07 (100.0%), 327.07 (19.5%), 328.08 (1.8%) |
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Kev Ntsuam Xyuas |
C, 66.26; H, 4.63; O, 19.61; P, 9.49 |
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Melting point |
{{0 {}} degree (lit.) |
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Kub taw tes |
244 Degree / 10 MmHg (Lit.) |
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Ceev |
1.2055 |
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Kev Cia |
Khw hauv qab +30 degree. |
Nplaim taws retardant
TPP (Triphamenyl phosphate) Tseeb txaus siab rau kev ua haujlwm thoob plaws raws li cov nplaim halogen-dawb retardant nyob rau hauv ntau ntau yam khoom ntawm cov ntaub ntawv. Nws txoj haujlwm tseem ceeb yog kom txhim kho cov nplaim hluav taws xob ntawm ntau cov substrates, xws li engineering strastics thiab Phenolico resin laminated laug cam. Los ntawm kev sib xyaw TPP rau hauv cov ntaub ntawv no, lawv cov nplaim taws yog cov cim txo. Qhov kev txhim kho no hauv cov nplaim hluav taws tsis tsuas yog ua kom haum nrog kev loj hlob ntawm kev nyab xeeb ntawm cov ntawv thov uas tau siv cov khoom siv no. Los ntawm cov khoom siv hauv tsheb rau cov khoom siv hluav taws xob thiab dhau mus, TPP ua si lub luag haujlwm tseem ceeb hauv kev ua kom muaj kev nyab xeeb thiab kev ntseeg tau ntau yam ntawm ntau yam khoom.
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Yas ua
TPP cov haujlwm tsis yog yog halogen-dawb nplaim retardant tab sis kuj yog cov yas yas. Nws lub luag haujlwm yog cov yas yas yog los txhim kho qhov hloov tau thiab muaj txiaj ntsig ntawm cov polymers, ua rau muaj ntau yam ntxiv thiab yooj yim ua haujlwm nrog thaum lub sijhawm tsim khoom.
Nyob rau hauv kev tsim cov hluavtaws rubbers, TPP ua haujlwm ua ib qho muag muag muag. Los ntawm kev sib xyaw ua ke TPP, cov roj hmab sib txuas ua softer thiab ntau pliables, tso cai rau kev txhim kho kev ua cov yam ntxwv thiab tsim qauv. Qhov no ua rau TPP tshwj xeeb muaj txiaj ntsig hauv cov khoom siv roj hmab ntau yam xws li cov log tsheb, thiab koj txoj siv sia, qhov twg yog qhov tseem ceeb heev.
Qhov yooj yim cov nyhuv ntawm TPP kuj txuas rau lwm cov ntaub ntawv ntawm polymer-based, xws li polyvinyl chloride (PVC) thiab polyurethanes. Hauv cov ntawv thov no, TPP pab txhawm rau txhim kho cov khoom ntws ntawm cov polymers, ua rau lawv yooj yim dua rau hauv ntau yam duab thiab ntau thiab tsawg. Qhov no, nyeg, txhim kho cov kev ua tau zoo tag nrho thiab cov khoom lag luam ntawm kev tsim khoom.
Zuag qhia tag nrho, TPP cov kev ua haujlwm ob npaug li ob qho tib si plhaw retardant thiab cov yas muaj txiaj ntsig ntxiv rau ntau yam khoom siv polymer, txhim kho lawv cov kev ua tau zoo thiab cov versatility hauv ntau yam kev siv.
Kev Siv Hluav Taws Xob Hluav Taws Xob
TPP muaj peev xwm muaj peev xwm nyob hauv cov khoom siv hluav taws xob vim nws qhov tshwj xeeb chemical Astrivity. Ib qho tseem ceeb uas tpp tuaj yeem yauv tau yog nitration, qhov uas nws nyiam nrog nitric acid lossis nws cov derivatives los hloov phenyphates hloov Penylphates.
Piv txwv li, TPP tuaj yeem nitrated los tsim tris ({0}} nitropheny lossis tris (2, {2}} dinphote. Cov khoom siv Penyyl phosphatates muaj cov tshuaj sib txawv thiab lub cev piv rau TPP, ua rau lawv haum rau ntau yam kev siv hauv kev lag luam tshuaj.
Cov versatility ntawm TPP hauv kev tawm tsam zoo li no tso cai rau nws ua cov khoom siv pib lossis nruab nrab hauv cov xwm txheej ntawm lwm yam tshuaj lom neeg. Qhov no ua rau TPP ib qho khoom muaj txiaj ntsig zoo nyob hauv thaj teb cov khoom siv hluav taws xob, qhov chaw nws tuaj yeem siv los tsim cov khoom sib txuas nrog cov khoom sib txuas thiab ua haujlwm tshwj xeeb.
Tsis tas li ntawd, muaj lub peev xwm ntawm TPP kom yauv tsis muaj nitration thiab lwm yam kev siv tshuaj lom neeg ua tau pom tias lub tsev ua haujlwm hauv synthesis ntawm cov molecules ntau. Qhov no ua rau TPP ib qho khoom siv tau zoo nyob rau hauv txhais tes ntawm cov organic cov organic, uas tuaj yeem siv nws cov kev cuam tshuam rau kev tsim qauv thiab ua ke nrog cov khoom siv tshiab rau cov ntawv thov tshwj xeeb.
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Hnyav thiab Wedting Tus Neeg Sawv Cev
TPP's Solubility nyob rau hauv ntau ntawm cov organic cov kuab tshuaj, suav nrog benzene, chloroform, thiab acetone, undility nws nyob rau hauv ntau yam kev siv. Qhov solubility no ua rau TPP ib qho muaj txiaj ntsig lossis cov neeg ntub dej hauv nws txoj cai.
Hauv kev tsim cov nitrocellulose thiab cellulose acetate, TPP ua haujlwm rau ob lub ntsej muag zoo li ob lub nplaim taws-retardant yas thiab cov kub uas tiv thaiv hluav taws. Los ntawm kev sib xyaw ua si TPP rau hauv cov ntaub ntawv no, cov chaw tsim khoom tuaj yeem txhim kho lawv cov nplaim taws tiv thaiv thiab ua kom muaj kev nyab xeeb dua thiab muaj peev xwm siv.
Ntxiv rau nws siv hauv plastics thiab resins, TPP kuj pom cov ntawv thov uas ntub tus neeg sawv cev. Nws muaj peev xwm ntub thiab nkag rau ntau qhov chaw ua rau nws xaiv cov khoom lag luam nitrocellulose, hluavtaws resins, thiab cov ntaub ntawv hluavtaws. Hauv cov ntawv thov no, TPP pab kom ntseeg tau tias cov khoom siv txheej txheej, txhim kho qhov zoo tagnrho thiab ruaj khov ntawm cov khoom tiav.
Zuag qhia tag nrho, TPP's Solubility hauv Organic cov kuab tshuaj, sib xyaw nrog nws cov nplaim taws, ua rau nws muaj kuab lom heev thiab muaj txiaj ntsig zoo hauv cov ntawv thov. Seb puas yog cov kuab tshuaj, yas, lossis ntub dej yog lub luag haujlwm tseem ceeb hauv kev txhim kho kev ua tau zoo thiab kev nyab xeeb ntawm ntau cov ntaub ntawv thiab cov khoom lag luam.
Hloov chaw tsim khoom
TPP tuaj yeem ua haujlwm los hloov chaw rau lub camphor hauv kev tsim cov celluloid.
Raws li ib tug xaiv ppp modulator
Kev Tshawb Nrhiav Kev Tshawb Fawb
Peroxisome Prooliferator-activated receptor (Ppp) yog koom nrog kev tswj hwm ntau yam kev sib txawv, cov tshuaj insulin kuj, thiab cov teb mob heev. Xaiv PARD Modulators (spparms) tsom kom tau txais txiaj ntsig zoo ntawm cov tshuaj muaj txiaj ntsig los ntawm cov neeg muaj txiaj ntsig thaum txo cov kev tsis zoo.
Muaj peev xwm ntawm TPP
Cov kev tshawb fawb tau qhia tias TPP lossis nws cov derivatives yuav muaj lub peev xwm ua tau raws li xaiv cov PARp modulators. Txawm li cas los xij, kev tshawb fawb hauv daim teb no tseem nyob rau hauv nws qib pib, xav tau cov pov thawj ntxiv los txhawb nws daim ntawv thov kev siv.
Inducing macrophage tab kaum
Kev Tshawb Nrhiav Kev Tshawb Fawb
MacRophages yog ib yam tseem ceeb ntawm tes hauv kev tiv thaiv kab mob hauv lub cev thiab muaj ntau yam ntawm cov teeb meem ntawm lub cev xws li kev kho mob hnyav thiab cov nqaij mos. Lub ERK / NF-κB signaling pathwing pathwing los ntawm tl4 (hu-zoo li receptor 4) ua si lub luag haujlwm tseem ceeb hauv kev ua haujlwm ntawm macrophages.
Lub luag haujlwm ntawm TPP
Cov kev tshawb fawb tau qhia tias TPP yuav ua rau muaj macrofunction tsis zoo los ntawm kev ua haujlwm rau lub erk / nf-κb signing pathwing los ntawm tl4. Qhov kev siv tshuab ntawm kev nqis tes ua no yuav ua rau kev ua kom tsis zoo lossis cuam tshuam rau lub cev lus teb, yog li cuam tshuam rau lub cev lus teb thiab cov nqaij mos txheej txheem. Txawm li cas los xij, kev tshawb fawb nyob rau thaj chaw no tseem yuav tsum tau ua pov thawj kev sim rau kev tshawb xyuas ntxiv thiab kev tshawb nrhiav hauv qhov tob.
Triphamenyl phosphate(TPP), tseem hu ua Phosphate Triphenyfyl Ester, yog ib hom organic phosphorus sib xyaw nrog cov tshuaj noj tshuaj c18h15o4p. Cov kev tshawb fawb thiab kev tsim kho tuaj yeem raug taug qab rau nws cov ntaub ntawv synthesis thiab txuas ntxiv los ntawm kev tshawb nrhiav kev tshawb fawb txog nws cov khoom, kev cuam tshuam ib puag ncig, thiab ib puag ncig cuam tshuam.
TPP tau ua thawj synthesized rau kev lag luam siv vim nws cov nplaim taws zoo-retardant thiab yas ua tej yam. Nws cov tshuaj ruaj khov, nrog lub taw tes melting ntau ntawm 47-53
Sij hawm dhau los, kev tshawb fawb science tau sib nkag siab tob los tob tob ntawm TPP. Cov kev tshawb fawb pom tau tias TPP tuaj yeem tsiv mus nyob hauv ib puag ncig los ntawm kev loj hlob thiab kev sib txawv, thiab tom qab kev cuam tshuam ecosystem. Piv txwv li, TPP tau raug kuaj pom hauv dej, av, plua plav, thiab txawm tib neeg lub cev. Kev tshawb fawb tau hais txog nws lub peev xwm los ua rau muaj kev ntxhov siab, kev loj hlob toxicity, metabolic tsis muaj kev cuam tshuam, thiab kev ua me nyuam lom.
Tsis ntev los no, nce qib tseem ceeb tau ua nyob rau hauv elucidating lub molecular txheej txheem ntawm TPP's Toxicity. Kev tshawb fawb luam tawm hauv phau ntawv ceev xwm txheej ntawm cov khoom txaus ntshai hauv 2023 qhia tau tias TPP Induces muaj kev ua me nyuam muaj kuab lom los ntawm JNK kev piav qhia txoj hauv kev. Qhov kev tshawb pom no ntxiv rau lub cev loj hlob ntawm cov pov thawj txog TPP cov kev cuam tshuam tsis zoo ntawm biological.
Tsis tas li ntawd, TPP cov kev txhawj xeeb ib puag ncig tau ua rau muaj kev cai ua. Lub Kaum Ib Hlis 2024, European Tshuaj Txuj Ci (cha Europe) Ntxiv TPP rau cov khoom muaj kev txhawj xeeb (SVHC) nyob rau hauv kev xav tau ntawm kev tswj hwm kev sab nraud thiab tswj cov tshuaj no.
Hauv cov ntsiab lus, cov kev tshawb fawb thiab kev txhim kho ntawm TPP tau hloov kho los ntawm nws cov ntawv thov kev lag luam rau kev nkag siab zoo txog nws cov tshuaj lom thiab ib puag ncig cuam tshuam. Raws li kev paub txog kev paub txog kev kawm txog kev kawm tau zoo, yog li cov kev cai ntsuas tsom rau kev tiv thaiv tib neeg kev noj qab haus huv thiab ib puag ncig los ntawm cov kev puas tsuaj ntawm TPP.
Cim npe nrov: Tripheryl phosphate CAS 115-86-6, cov chaw muag khoom, chaw tsim khoom, Hoobkas, yuav, nqe, loj, rau muag