Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm di-tert-butylchlorophosphane cas 13716-10-4 hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo di-tert-butylchlorophosphane cas 13716-10-4 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Di-tert-butylchlorophosphaneyog Organophosphorus chemistry, nws cov mis Molecular yog C8H19ClP, CAS 13716-10-4. Nws feem ntau yog cov kua tsis muaj xim nrog cov ntxhiab tsw tshwj xeeb thiab tej zaum yuav ua rau khaus, tab sis nws tuaj yeem tsim cov khoom ntawm qhov kub thiab txias. Cov tshuaj no yog volatile thiab tuaj yeem evaporate mus rau hauv lub xeev gaseous. Nws yog cov kuab tshuaj organic uas yog soluble hauv tsis yog{11}}cov kuab tshuaj organic xws li benzene, toluene, thiab ether. Txawm li cas los xij, solubility hauv dej yog qhov tsawg. Nws yog ib yam khoom uas combustible uas tuaj yeem hlawv nyob rau hauv qhov tsim nyog. Thaum kub hnyiab hauv huab cua, cov roj chlorine muaj kuab lom. Zoo sib xws, tab sis tej zaum yuav rhiab heev rau oxygen thiab dej, yooj yim hydrolyzing los tsim hydrogen chloride thiab di{14}}tert-butylphosphate. Ligands feem ntau yog siv rau catalysts rau asymmetric coupling ntawm palladium complexes. Peb yog Shaanxi Achieve chem-tech Co., Ltd. Peb tsim thiab tsim cov khoom no peb tus kheej. Yog tias koj xav tau, koj tuaj yeem xa peb cov lus nug.
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Tshuaj Formula |
C8H18 CWB |
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Exact Mass |
180 |
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Molecular Luj |
181 |
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m/z |
180 (100.0%), 182 (32.0%), 181 (8.7%), 183 (2.8%) |
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Elemental Analysis |
C, 53,19; H, 10.04 Nws; lus, 19,62; Ib., 17.15 |
Di tert butylphosphine chloride (CAS naj npawb: 13716-10-4, molecular mis: C ₈ H ₁₈ ClP) yog ib qho organic phosphine compound uas zoo li tsis muaj xim rau daj daj ua kua ntawm chav tsev kub. Nws yog heev corrosive thiab rhiab heev rau huab cua, noo noo, thiab alkaline tshuaj. Nws yuav tsum tau muab khaws cia rau hauv ib qho kev sib khi nyob rau hauv inert gas tiv thaiv. Nws cov qauv tshuaj tshwj xeeb (ob pawg tert butyl txuas nrog phosphorus atom thiab nqa cov tshuaj chlorine atom) ua rau nws yog ib qho tseem ceeb hauv kev lag luam chemistry, biology, thiab cov ntaub ntawv science.
Daim ntawv thov dav tshaj plaws yog raws li ligand, koom nrog hauv palladium catalyzed coupling cov tshuaj tiv thaiv, tshwj xeeb tshaj yog Suzuki Miyaura cross coupling tshua. Cov tshuaj tiv thaiv no yog ib txoj hauv kev tseem ceeb rau kev tsim cov pa roj carbon monoxide, dav siv hauv kev tsim tshuaj, kev npaj cov khoom ntuj tsim, thiab kev tsim cov khoom siv polymer.
1. Kev siv txuas ntxiv ntawm lwm cov kev sib txuas sib txuas
Ntxiv rau Suzuki cov tshuaj tiv thaiv, nws kuj tuaj yeem siv rau Heck cov tshuaj tiv thaiv (tsim olefin aryl bonds), Negishi cov tshuaj tiv thaiv (coupling ntawm alkyl zinc reagents nrog aryl halides), thiab Buchwald Hartwig amination cov tshuaj tiv thaiv (tsim carbon nitrogen bonds).
Piv txwv li, nyob rau hauv cov synthesis ntawm cov tshuaj tiv thaiv kab mob HIV Etravirine, lub ligand txhawb palladium catalyst tuaj yeem ua tau zoo ob peb indole nrog aryl bromide nyob rau hauv cov tshuaj tiv thaiv me me (chav kub, huab cua cua), thiab cov tshuaj catalyst tsawg li 0.1 mol%.
2. Kev tawg hauv Asymmetric Catalysis
Los ntawm kev hloov kho cov qauv (xws li qhia cov chaw chiral), chiral ligands tuaj yeem muab tau rau cov tshuaj tiv thaiv asymmetric catalytic. Piv txwv li, los ntawm kev sib txuas nrog palladium lossis rhodium, asymmetric hydrogenation cov tshuaj tiv thaiv tuaj yeem ua rau muaj kev sib txuas ntawm chiral alcohols lossis amines, thiab enantioselectivity (ee tus nqi) ntawm cov khoom tuaj yeem ncav cuag ntau dua 99%. Hom chiral catalyst no muaj nuj nqis tseem ceeb hauv kev tsim cov tshuaj chiral, xws li cov tshuaj tiv thaiv kev nyuaj siab paroxetine.
Nyob rau hauv xyoo tas los no, vim nws qhov tshwj xeeb lom neeg ua si, nws tau dav siv nyob rau hauv cov synthesis ntawm anticancer, antiviral, thiab antibacterial tshuaj, los ua ib tug "lub hnub qub nruab nrab" nyob rau hauv lub teb ntawm tshuaj chemistry.
1. Synthesis ntawm cov tshuaj tiv thaiv kab mob
Raws li tus precursor, nws tuaj yeem nkag mus rau hauv cov tshuaj molecules los ntawm kev hloov tshuaj lom neeg los txhim kho cov hom phiaj tshuaj lossis kev ruaj ntseg. Piv txwv li, thaum synthesizing analogs ntawm platinum raws li tshuaj tiv thaiv kab mob Oxaliplatin, kev koom tes nrog lub platinum center tuaj yeem tsim cov dej ntau dua -soluble complex, txo cov neurotoxicity ntawm cov tshuaj. Tsis tas li ntawd, nws cov derivatives tuaj yeem ua raws li protease inhibitors los thaiv cov kev taw qhia ntawm cov qog hlwb.
2. Kev tsim cov tshuaj tiv thaiv kab mob
Nyob rau hauv lub synthesis ntawm cov tshuaj antiviral,di-tert-butylchlorophosphanefeem ntau yog siv los tsim cov nucleoside analogues. Piv txwv li, hauv kev sib txuas ntawm cov tshuaj tiv thaiv kab mob HIV Atazanavir, nws cov phosphorylated derivatives tuaj yeem ua cov khoom noj qab zib, khi rau nucleoside hauv paus los ntawm glycosidic bonds los tsim cov nucleoside analogs nrog cov tshuaj tiv thaiv kab mob. Hom tshuaj no tuaj yeem cuam tshuam cov haujlwm ntawm tus kab mob rov qab transcriptase lossis protease, yog li thaiv cov kab mob sib kis.
3. Cov tshuaj tua kab mob thiab biomarkers
Cov phosphorus atom ntawm di tert butylphosphine chloride tuaj yeem sau npe nrog cov isotopes radioactive (xws li ³ ² P) rau kev kuaj ntshav lossis tshuaj xyuas. Piv txwv li, tom qab txhaj cov ntawv sau rau hauv lub cev, kev faib tawm thiab cov metabolism hauv cov tshuaj hauv lub cev tuaj yeem saib xyuas lub sijhawm tiag tiag los ntawm PET (positron emission tomography) thev naus laus zis, muab lub hauv paus rau kev siv tshuaj zoo. Tsis tas li ntawd, nws cov phosphorylated derivatives kuj tuaj yeem ua cov tshuaj tua kab mob, inhibiting kev tsim cov kab mob biofilms.
Cov Khoom Siv Kev Tshawb Fawb: Cov qauv hloov kho rau cov khoom siv ua haujlwm
Kev hloov kho tshuaj tuaj yeem ua ke nrog cov khoom siv polymers, nanomaterials, lossis optoelectronic cov ntaub ntawv los pab lawv nrog cov haujlwm tshiab thiab nthuav dav lawv cov kev siv hauv thaj chaw ntawm lub zog, hluav taws xob, thiab ib puag ncig.
1. Kev ua haujlwm ntawm cov khoom siv optoelectronic
Nyob rau hauv cov ntaub ntawv organic electroluminescent (OLEDs), lawv cov derivatives tuaj yeem ua cov txheej txheem thauj hluav taws xob lossis lub qhov thaiv cov khaubncaws sab nraud povtseg txhawm rau txhim kho luminescence efficiency thiab ruaj khov ntawm cov cuab yeej. Piv txwv li, kev qhia nws mus rau hauv cov ntaub ntawv polyfluorene tuaj yeem txhim kho lub teeb xiav emission kev ua tau zoo ntawm cov khoom siv, thiab cov cuab yeej siv tau tuaj yeem nce ntau dua li ob zaug ntawm cov khoom siv ib txwm muaj. Tsis tas li ntawd, nws cov phosphorylated derivatives kuj tseem siv tau los ua cov sensitizers rau lub hnub ci hlwb los txhim kho lub teeb pom kev zoo.
2. nplaim retardant hloov ntawm cov ntaub ntawv polymer
Nws cov phosphorus chlorine daim ntawv cog lus tuaj yeem decompose rau hauv phosphoric acid thiab hydrogen chloride ntawm qhov kub thiab txias, tsim ib txheej carbonized uas tiv thaiv nplaim taws. Yog li ntawd, nws cov derivatives (xws li phosphorus nitrogen synergistic nplaim retardants) yog dav siv rau cov nplaim hluav taws kub hloov pauv ntawm cov ntaub ntawv polymer xws li polyethylene, polypropylene, thiab polyurethane. Piv txwv li, ntxiv 5% di tert butylphosphine chloride raws li cov nplaim hluav taws kub nyhiab rau polypropylene tuaj yeem ua rau kom muaj qhov txwv oxygen index (LOI) ntawm cov khoom los ntawm 18% mus rau 28%, ua tau raws li UL94 V-0 nplaim retardant tus qauv.
3. Kev hloov kho deg ntawm nanomaterials
Qhov saum npoo ntawm cov hlau nanoparticles (xws li kub thiab nyiaj nanoparticles) los yog quantum dots tuaj yeem hloov kho los ntawm kev sib koom tes los txhim kho lawv txoj kev ruaj ntseg thiab biocompatibility. Piv txwv li, siv cov hloov pauv kub nanoparticles hauv biosensors tuaj yeem txhim kho cov teeb liab rhiab heev nrog kev kuaj pom qhov tsawg li pM qib. Tsis tas li ntawd, nws cov phosphorylated derivatives kuj tuaj yeem ua cov qauv los tswj cov morphology thiab qhov loj ntawm nanomaterials.
1. Direct alkylation ntawm phosphine chloride:
Kauj Ruam 1: Kev npaj ntawm chlorinated Tributylphosphine tetrabutyl ammonium ntsev
Reaction tshuaj formula:
(CH3CH2CH2) 3PCl + (CH3CH2CH2CH2) 4NCO → [(CH3CH2CH2) 3P (CH2CH2CH2CH2) 4N] Cl + HCl
Ua ntej, yaj Tributylphosphine chloride ((CH3CH2CH2) 3PCl) thiab tetrabutylammonium chloride ((CH3CH2CH2CH2) 4NCl) nyob rau hauv ethanol hnyav, thiab kub thiab do cov tshuaj tiv thaiv sib tov. Qhov no yuav ua rau muaj kev cuam tshuam thiab tsim cov chlorinated Tributylphosphine tetrabutyl ammonium ntsev.
Kauj ruam 2: Synthesis ntawm cov khoom:
Reaction tshuaj formula:
[(CH3CH2CH2) 3P (CH2CH2CH2CH2) 4N] Cl + ClC (CH3) 3→ [(CH3CH2CH2)3P(CH2CH2CH2CH2)4N] (C(CH3) 3) Cl + ClCH2C (CH3) 3
Dissolve cov chlorinated Tributylphosphine tetrabutyl ammonium ntsev tau nyob rau hauv kauj ruam 1 nyob rau hauv lub ethanol hnyav nyob rau hauv alkaline tej yam kev mob, ntxiv chloroethane thiab kub nws. Nyob rau hauv cov xwm txheej no, Nucleophilic hloov pauv yuav tshwm sim, thiab pawg tert butyl tau qhia rau Tributylphosphine los ua Di tert butyl chlorophosphane. Cov khoom kawg tau txais yogDi-tert-butylchlorophosphane([(CH3CH2CH2)3P(CH2CH2CH2CH2)4N](C(CH3)3Cl). Nws muaj phosphorus atoms hloov nrog tert butyl thiab chloride pawg, nrog rau tetrabutylammonium cations.
2. Phosphorus tshuaj txo txoj kev:
Kauj Ruam 1: Synthesis ntawm tributylphosphine chloride:
Ua ntej, hnov mob phosphine chloride (PCl3) nrog tributyl aluminium (Al (CH3CH2CH2)3) los tsim tributylphosphine chloride (CH3CH2CH2)3PCl). Cov tshuaj tiv thaiv no feem ntau yog ua los ntawm cov roj inert (xws li nitrogen lossis argon), thiab lub sijhawm kub thiab cov tshuaj tiv thaiv raug tswj.
Kauj Ruam 2: Kev Npaj Lithium phosphide:
Cov hlau lithium (Li) reacts nrog Phosphine (PH3) tsim Lithium phosphide (Li3P). Cov kauj ruam no yuav tsum tau ua nyob rau hauv inert gas, feem ntau yog ua kua ammonia (NH3), thiab cov tshuaj tiv thaiv yog tswj los ntawm maj mam ntxiv lithium hlau thiab Phosphine.
Kauj Ruam 3: Synthesis ntawm cov khoom:
React tributylphosphine chloride tau nyob rau hauv kauj ruam 1 nrog Lithium phosphide tau nyob rau hauv kauj ruam 2. Nyob rau hauv ib tug tsim nyog hnyav, xws li ether los yog tetrahydrofuran (THF), maj mam ntxiv tributylphosphine chloride rau Lithium phosphide kua, thiab tag nrho do kom tov cov reactants. Nyob rau hauv cov xwm txheej zoo li no, tributylphosphine chloride tau hloov pauv Nucleophilic, thiab pawg tertiary butyl tau qhia rau phosphorus atom los ua Di tert butyl chlorophosphane.
Cov khoom kawg tau txais yog nws (CH3CH2CH2)3P (CH2CH2CH2CH2)4N). Nws muaj tert butyl hloov phosphorus atoms thiab tetrabutylammonium cations.
Cov no yog ob txoj kev sib xyaw ua ke rauDi-tert-butylchlorophosphane. Kev tshawb fawb sib txawv thiab daim ntawv thov kev lag luam tuaj yeem siv ntau txoj hauv kev, thiab cov kev sib txuas tshwj xeeb kuj tuaj yeem hloov kho thiab ua kom zoo raws li qhov xav tau tiag tiag. Hauv kev sim ua haujlwm, nws yog ib qho tseem ceeb uas yuav tsum tau ua raws li kev ntsuas kev nyab xeeb tsim nyog thiab ua raws li cov txheej txheem kev ua haujlwm hauv chaw soj nstuam kom muaj kev nyab xeeb thiab ua haujlwm ntawm cov txheej txheem synthesis.
Cim npe nrov: di-tert-butylchlorophosphane cas 13716-10-4, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom