Shaanxi Bloom Tech Co., Ltd. yog ib qho kev paub txog cov neeg tsim khoom thiab cov chaw muag khoom ntawm lub suab malate 10 mg hauv Suav teb. Txais tos rau kev lag luam wholesale ntau qhov zoo acepromazine malaste 10 mg rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
AcePromazine Malaste 10 mg, raws li kev siv dav siv tshuaj nyob rau hauv cov kws kho tsiaj, ua kom muaj kev pab rau tsiaj txhu, kev pab tshuaj loog, tiv thaiv kev poob siab thiab lwm yam. Nws zwm rau chav kawm ntawm phenothivezine derivatives, thiab txij li nkag mus rau cov tshuaj kho tsiaj rau hauv cov khoom kho tsiaj rau hauv cov kws kho tsiaj rau hauv cov khoom kho tsiaj rau hauv cov kws kho tsiaj thiab cov khoom siv hluav taws xob zoo.
Kev ruaj khov thiab chaw cia khoom:
Qhov kev ruaj ntseg ntawm Acetylromethazine Marate Txhaj Tshuaj yog cuam tshuam heev los ntawm kev cia khoom. Feem ntau hais lus, nws yuav tsum muab cia rau hauv qhov tsaus ntuj thiab nyob rau hauv chav tsev kub los tiv thaiv kev tsis txaus siab yeeb tshuaj thiab tsis ua tiav. Thaum lub sijhawm thauj mus los, nws tseem tsim nyog ua raws li kev thauj mus los no kom tsis txhob muaj kev cuam tshuam zoo xws li kev co thiab kub thiab txias rau cov tshuaj. Yog tias cov kev daws teeb meem yuav tsum npaj ua ntej, nws raug nquahu kom khaws cov tshuaj fwj me me hauv -20℃c, uas feem ntau tuaj yeem siv rau li ib hlis. Ua ntej siv thiab qhib tus qauv fwj, cov khoom yuav tsum tau tso cai rau equilibibrate nyob rau hauv chav tsev kub tsawg kawg 1 teev kom ntseeg tau tias qhov kev ruaj ntseg thiab ua tau zoo ntawm cov tshuaj.
Peb Cov Khoom
Cov ntaub ntawv ntxiv ntawm kev sib txuas lus:
| Khoom npe | AcePromazine Malaste ntsiav tshuaj | AcePromazine Marate Txhaj |
| Khoom Yam | Ntsiav tshuaj | Kev txhaj tshuaj |
| Khoom Siv Purity | Ntau dua los yog sib npaug rau 99% | Ntau dua los yog sib npaug rau 99% |
| Cov Khoom Qhia Khoom Khoom | Tau sib kho | Tau sib kho |
| Khoom Pob | Tau sib kho |
Tau sib kho |
AcePromazine Marate +. coa
 |
||
Daim Ntawv Pov Thawj Kev Ntsuam Xyuas |
||
|
Compound npe |
AcePromazine Malaste | |
|
Cas Tsis tau. |
3598-37-6 | |
|
Teem nqi |
Kws Tshuaj Ntsuam Xyuas | |
|
Qho ntau |
Me nyuam | |
|
Ntim txheem ntim |
Me nyuam | |
| Tus tsim | Shaanxi Bloom Tech Co., Ltd. | |
|
Lauj tsis tau. |
20250109001 |
|
|
Mfg |
Jan 12th 2025 |
|
|
Tus txeeb |
Jan 8th 2029 |
|
|
Lub tsev |
|
|
| Kuaj Tus Qauv | GB / T24768-2009 kev lag luam. Stnndard | |
|
Yam |
Kev Lag Luam Kev Lag Luam |
Kev tsom xam tau |
|
Kev tshwm sim |
Dawb lossis yuav luag dawb hmoov |
Hloov |
|
Dej Cov Ntsiab Lus |
Tsawg dua los yog sib npaug rau 4.5% |
0.30% |
| Poob rau ziab |
Tsawg dua los yog sib npaug rau 1.0% |
0.15% |
|
Cov hlau hnyav |
PB tsawg dua lossis sib npaug rau 0.5ppm |
N.D. |
|
Tsawg tsawg dua li lossis sib npaug rau 0.5ppm |
N.D. | |
|
Hg tsawg dua lossis sib npaug rau 0.5ppm |
N.D. | |
|
CD tsawg dua lossis sib npaug rau 0.5ppm |
N.D. | |
|
Purity (hplc) |
Ntau dua los yog sib npaug rau 99.0% |
99.5% |
|
Ib Leeg Cav |
<0.8% |
0.48% |
|
Residue ntawm ignition |
<0.20% |
0.064% |
|
TAG NRHO LICBIAL COUNT |
Tsawg dua li lossis sib npaug rau 750cfu / g |
80 |
|
E. coli |
Tsawg dua los yog sib npaug rau 2mpn / g |
N.D. |
|
Tus ntses siav |
N.D. | N.D. |
|
Ethanol (los ntawm gc) |
Tsawg dua los yog sib npaug rau 5000ppm |
400ppm |
|
Chaw ntim khoom |
Khaws rau hauv ib qho chaw sib khi, qhov chaw tsaus thiab qhuav ntawm-20 degrees |
|
|
|
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AcePromazine Malaste 10 mgyog ib feem ntau siv tshuaj nyob rau hauv cov kws kho tsiaj, thiab nws cov kev qhia tshwj xeeb muaj cov yam ntxwv tseeb ntawm daim ntawv, cov ntsiab lus, ntim, raws li hauv qab no:
1. Cov qauv tshwj xeeb
Acetylrometazin malate txhaj tshuaj yog feem ntau yog kev txhaj tshuaj, uas ua rau muaj cov tshuaj tiv thaiv tau zoo thiab kev txhaj tshuaj ntawm cov neeg siv cov kws kho vaj tsev hauv kev tshawb fawb hauv chaw kho mob. Cov ntsiab lus ntawm cov tshuaj acetylrromazine malate hauv txhua qhov kev txhaj tshuaj feem ntau 20 milligrams, uas txhais tau tias yog 13, milligrams ntawm acetylpromazine. Tus tsim qauv no ntawm daim ntawv no cov kev qhia tshwj xeeb tsis tsuas yog txiav txim siab qhov ua tau zoo thiab ruaj khov ntawm cov tshuaj, tab sis kuj tau yooj yim kho cov tsiaj siv tsiaj siv.
2. Cov ntsiab lus tshwj xeeb
Tej zaum yuav muaj qee yam sib txawv hauv cov ntsiab lus specifications ntawm Acetylprometazin Malate Txhaj Tshuaj los ntawm cov chaw tsim khoom sib txawv. Ntxiv rau cov nquag muaj 20mg / 2mL cov lus qhia tau hais los saum toj no, tej zaum yuav muaj lwm yam tshwj xeeb ntawm cov khoom lag luam, xws li 10mg / 1mL. Cov khoom lag luam ntawm cov kev sib txawv cov lus tshwj xeeb tau raws li cov kev xav tau ntawm cov tsiaj sib txawv, cov mob sib txawv, thiab cov tshuaj sib txawv. Cov kws kho tsiaj yuav tsum xaiv cov tshuaj uas tsim nyog rau cov tshuaj raws cov xwm txheej tshwj xeeb.
3. Ntim cov lus qhia tshwj xeeb
Kuj tseem muaj ntau cov ntim cov khoom ntim rau acetylpromazine malate txhaj. Cov khoom ntim khoom uas ib txwm ntim yog ib qho kev ntim khoom ywj pheej, uas txhua qhov kev txhaj tshuaj yog ntim hauv ib pob sib cais kom ntseeg tau tias cov tshuaj. Ib qho ntxiv, yuav muaj ntim cov ntawv ntau hauv ib lub thawv, xws li 5 chav nyob ntawm cov ntaub ntawv ntim khoom, ntxiv rau cov neeg siv khoom siv tau thiab siv los ntawm cov kws kho tsiaj.
4. Tshwj xeeb specifications thiab customization
Ntxiv rau cov lus qhia tshwj xeeb uas tau hais los saum toj no, qee cov tuam ntxhab kuj tseem yuav ua cov kev paub meej meej ntawm Acetylprometazin Malaste txhaj tshuaj raws li kev xav tau lag luam thiab cov neeg siv khoom xav tau. Piv txwv li, rau qee cov tsiaj loj lossis cov tshuaj tshwj xeeb, cov tshuaj tshwj xeeb ntawm cov tshuaj noj yuav tsum muaj, thiab cov tuam ntxhab yuav muab cov ntsiab lus ntau dua lossis cov ntaub ntim ntau dua lossis cov ntim ntau dua. Ib qho ntxiv, qee cov chaw tshawb fawb tseem ceeb yuav tsum tau kho cov kev paub tseeb ntawm Acetylprometazin kev sim tshuaj tau ua kom tau raws li lawv cov kev sim kev sim tshwj xeeb.
Cov lus qhia tshwj xeeb thiab kev siv cov kev ceev faj:
Cov kws kho tsiaj yuav tsum txiav txim siab xws li tus tsiaj lub cev hnyav, noj tshuaj, thiab kev tswj hwm lub hom phiaj, thiab kev tswj hwm kev siv rau acetylrometazin malate txhaj. Rau cov tsiaj me xws li dev, miv, thiab lwm yam, yog cov lus qhia tshwj xeeb ntawm 20 milligrams / 2 lab) feem ntau yog qhov txaus kom tau raws li cov kev xav tau; Rau cov tsiaj loj xws li nees, nyuj, thiab lwm yam, cov khoom siv ntau dua lossis cov ntaub ntim ntau dua yuav tsum tau xaiv. Tib lub sijhawm, thaum lub sijhawm siv, kws kho tsiaj yuav tsum ua raws cov lus qhia tshuaj lossis cov lus qhia ntawm cov kws kho tsiaj kom tsis txhob siv ntau dhau los yog cov tswj hwm ntau.
Cov Qauv Hluav Taws Xob Tshaj Tawm
AcePromazine Malaste 10 mg, raws li ib qho tshuaj lom neeg tseem ceeb, muaj ntau cov kev siv hauv cov qauv ntawm cov tshuaj thiab lwm tus. Cov txheej txheem synthesis feem ntau yog tig mus ncig ntawm cov tshuaj tiv thaiv nruab nrab ntawm acetylpromazine thiab txiv neej kua qaub. Cov hauv qab no yuav muab cov lus qhia ntxaws ntxaws txog ob peb txoj kev muaj peev xwm thiab cov ntsiab lus tseem ceeb.
Synthesis txoj kev raws li Acetylpromazine Intermediate
1. Khoom cua ntawm Acetylpromazine
Pib xaiv cov khoom siv: cov hluavtaws ntawm Acetylpropazine feem ntau pib nrog phenottylropazine compound los ntawm cov tshuaj uas xav tau los ntawm cov tshuaj lom neeg. Piv txwv li, synthesis tuaj yeem nqa tawm siv 2-bromothopenol lossis phenothiazine nws tus kheej ua cov khoom pib.
Kev ua kom tau zoo ntawm cov tshuaj tiv thaiv kab mob: nyob rau hauv cov txheej txheem ntawm synthesizing acetylpromazine, nws yog qhov tsim nyog tswj cov tshuaj tiv thaiv kev ua tau zoo thiab kev coj dawb huv ntawm cov khoom. Nyob rau tib lub sijhawm, nws yog qhov tsim nyog los xaiv cov catalysts uas haum thiab cov kuab tshuaj los txhawb kev nce qib ntawm cov tshuaj tiv thaiv.
Cov Khoom Siv Tshuaj: Cov lus txhais tau Acetylpromazine Intermediate xav tau kom huv si kom tshem tawm impurities thiab tsis paub cov ntaub ntawv raw. Cov hau kev ua kom huv tib yam muaj xws li recrystallization, kem chromatography, thiab lwm yam.
2. Cov tshuaj tiv thaiv ntawm acetylpromazine nrog txiv neej acid
Cov tshuaj tiv thaiv lub hauv paus: acetylpromazine tuaj yeem hnov mob nrog txiv neej kua qaub nyob rau hauv cov cai tsim nyog los ua acetylpromazine malate. Qhov kev tawm tsam no feem ntau yog cov qeb ntawm cov kua qaub - cov tshuaj tiv thaiv kab mob los yog esterification.
Kev tiv thaiv kev tiv thaiv kev tswj hwm: Txhawm rau kom muaj kev kawm du ntawm cov tshuaj tiv thaiv, nws yog qhov tsim nyog kom tswj tau cov tshuaj tiv thaiv kev mob. Piv txwv li, kev tswj hwm kev tswj tau yog qhov yuav tsum tau rau cov tshuaj tiv thaiv kub, cov tshuaj tiv thaiv cov tshuaj tiv thaiv kev tiv thaiv los txhawb nqa cov tshuaj tiv thaiv thiab nce cov txiaj ntsig ntawm cov khoom.
Kev sib cais thiab kev ua kom huv: Tom qab cov tshuaj tiv thaiv tiav, cov khoom yuav tsum tau sib cais los ntawm cov tshuaj tiv thaiv los ntawm cov hau kev tsim nyog. Cov txheej txheem sib cais ntau yam suav nrog kev rho tawm, distillation, thiab lwm yam.
Synthesis cov tswv yim raws li cov txiv neej kua qaub derivatives
Ntxiv rau kev siv Acetylpromazine ua ib qho nrab rau synthesis, nws kuj tseem tuaj yeem xav txog kev siv cov txiv neej kua qaub ua cov ntaub ntawv raw liv rau synthesis. Hom qauv no yuav koom nrog cov tshuaj tiv thaiv txiv neej nrog lwm cov tebcom acid derivative intermediates, uas yog ces reacted nrog acetylpromazine lossis nws cov kev ua ntej.
1. Synthesis ntawm Muic Acid derivatives
Cov khoom siv raw: txiv plig anhydride, txiv neej monsic monoester, etc. tuaj yeem xaiv tau cov ntaub ntawv raw rau synthesizing cov txiv neej ua yeeb yam.
Cov kev mob tshwm sim: los ntawm kev tswj cov tshuaj tiv thaiv xws li kub, thiab lwm yam, txiv neej cov tshuaj reagents los tsim cov txiv neej xav tau tsim cov txiv neej.
2. Cov tshuaj tiv thaiv ntawm moovic acid derivatives nrog acetylpromazine
Hom: Qhov tshuaj tiv thaiv no yuav yog rau cov tshuaj tiv thaiv Esterification, kev hais txog kev coj ua, thiab lwm yam ntawm cov txiv neej acid derivative.
Cov tshuaj tiv thaiv optimization: txhawm rau txhim kho cov txiaj ntsig thiab kev coj dawb huv ntawm cov khoom lag luam, nws yog qhov tsim nyog los ua kom zoo rau cov tshuaj tiv thaiv. Piv txwv li, kho cov nqi hniav puas ntawm reactants, cov tshuaj tiv thaiv kub, sijhawm siv, thiab lwm lub sijhawm, thiab lwm lub sijhawm, thiab lwm lub sijhawm, lwm yam.
Cov tshuaj uas muaj feem xyuam ntsig txog cov ntsiab lus muaj raws li hauv qab no:
(1) nqus:
Muaj ntau txoj kev tswj hwmAcePromazine Malaste 10 mgrau miv, suav nrog cov khoom siv ntawm cov khoom siv, intramuscular, subcutaneous, thiab kev tswj hwm ntawm qhov ncauj. Muaj kev sib txawv hauv kev nqus cov tshuaj sib txawv hauv cov kev tswj hwm sib txawv, tab sis tam sim no muaj cov ntaub ntawv ntxaws ntxaws ntawm cov chaw muag tshuaj xws li nqus tau thiab degree. Txawm li cas los xij, txoj kev txhaj tshuaj ncov siab kawg tuaj yeem tshwm sim kwv yees li 5-15 feeb tom qab txhaj tshuaj ntxiv, uas rau qee qhov kev ntsuas ntawm cov tshuaj nkag mus rau hauv cov yeeb ncuab sib tw.
(2) faib:
Tom qab nkag mus rau lub cev, Acetylrpromazine MarEate yuav tau faib dav hauv ntau cov ntaub so ntswg thiab cov plab hnyuv siab raum. Nws cov txiaj ntsig zoo tshwm sim los ntawm kev cuam tshuam txog kev ua kom cov yeeb yaj kiab uas tau nkag rau hauv cov tshuaj hauv nruab nrab, ua raws li cov khoom siv cuam tshuam rau cov khoom siv cuam tshuam rau cov khoom siv hluav taws xob. Lub caij no, kev faib tshuaj ntawm lwm cov ntaub so ntswg thiab cov plab hnyuv kuj tuaj yeem cuam tshuam dab tsi, tab sis cov kev cuam tshuam tshwj xeeb thiab cov ntaub so ntswg tseem tsis tau meej.
(3) metabolism:
Tam sim no, muaj cov ncauj lus me me ntawm cov qauv metabolism, thiab cov enzymes ntawm acetylpromazine malate hauv lub cev. Cov tshuaj yauv ua cov txheej txheem biotransformation hauv lub cev, uas yuav tsim cov metabolites nrog cov khoom siv pharchar txawv sib txawv. Kev tsim khoom thiab tshem tawm ntawm cov metabolites kuj tseem tuaj yeem cuam tshuam tag nrho cov tshuaj ua tau zoo thiab kev nyab xeeb ntawm cov tshuaj.
(4) excretion:
Ib yam li ntawd, muaj ib qho tsis muaj cov ncauj lus kom ntxaws ntawm cov ntaub ntawv tshawb fawb xws li kev ua kom tiav, ua rau cov acetylpromazine malate. Cov tshuaj thiab lawv cov metabolites kuj yuav raug cais tawm ntawm cov zis hauv cov hnyuv los ntawm bile los ntawm bile los ntawm cov bile los ntawm kev siv hluav taws xob thiab cov ntsiab lus tsis meej.
Nws cov kev ntxhov siab ntawm daim membrane lub cev cov zog: los ntawm "fundicity" rau "theem hloov"
AcePromazine Malate, raws li ib qho kev ua yeeb yam ntawm Phenothomezine, tau siv dav hauv cov kws kho tsiaj ua haujlwm txij li xyoo 1950 ua tshuaj tiv thaiv, thiab tshuaj tiv thaiv kab mob. Nws cov tshuaj istic yog ib organic compound tsim los ntawm cov ntsev uas muaj cov yeeb yaj kiab ntawm 442.57, thiab xim daj lossis daj ua xim daj. Txawm hais tias nws cov teebmeem hluav taws xob, xws li alpras adeptor antagonism inclaries, tseem muaj ntau yam kev ntxhov siab ntawm lub cev ntawm daim nyias nyias nyias, tshwj xeeb yog nws qhov kev ntxhov siab ntawm cov fluition fluidity rau theem hloov.
Molecular hauv paus thiab membrane kev sib cuam tshuam
Membrane Embedding Cov yam ntxwv ntawm Phenottzine Nplhaib
Cov qauv tseem ceeb ntawm phenothiazine cov lus teb yog qhov sib txuas ntawm cov hlua khi (xws li koj cov khoom siv hydrothobic (thiab cov khoom siv hydrophlomic Acetyl Triazine Mareatded rau hauv phospholipid Bilayer ntawm cov qauv cenethia los ntawm cov qauv xov tooj ntawm cov phiaj xwm ntawm cov phiaj xwm ntawm cov phiaj xwm. Qhov no "amphiphilic" faib tawm "tso cai rau nws los cuam tshuam nrog kev txiav txim kev npaj ntawm daim di ncauj liprane.
Dopamine rappor antagharism thiab membrane teeb liab transduction
Acetylpromazine inhibits Central kom zoo li lub siab los ntawm thaiv dopamine d ₂ cov txheej txheem no yuav cuam tshuam rau membrane teeb liab transdal. Piv txwv li, D ₂ Receptor ua kom tau txais PHospholhetase C (PLC) kev ua, yog cuam tshuam rau membrane phospholip card metabolism. Cov nyhuv antagharist ntawm lub siab phem yuav txo qis floility ntawm membrane dampor
{{0- adrenergic receptor thaiv thiab membrane nruj kev cai
Lub {-}}}}}}}}}}}}}}}} ece receprpromazine tuaj yeem cuam tshuam nrog kev hloov pauv ntawm membrane nro. Kev ua kom muaj kev hloov kho ntawm Alpha ₁ receptors nce cov hydrolysis ntawm phosphatidylinositol 4,5-diphosplectol 4,5-diphosphate (IP α) thiab DAG cov duab liprane. Acetylpromazine tej zaum yuav txo tus membrane kom nruj thiab cuam tshuam rau qhov muaj qhov tawv tawv txhav ntawm daim ntaub thaiv no los ntawm kev thaiv txoj kev no.
Dynamic kev cai ntawm membrane fluity ntawm ib koob ntawm 10 mg
Kev sim ua pov thawj ntawm membrane fluidity
Membrane Fility yog lub cev tsis sib xws uas piav txog kev mus ncig uas muaj kev sib txuas lus, feem ntau ntsuas los ntawm fluorescent polamarization (EPR) cov tswv yim. Raws li kev txiav txim ntawm 10 mg ntawm Acetylrrethrometazine Marate, cov phenomena hauv qab no tau pom hauv kev sim:
Kev tawm tsam fluorescence polarization tus nqi: siv 1,6-diphenyl-1,3,5-hexane (dph)
Nqaim eprrowing epr spectral kab kab: siv 5-nitrooxystearic acid (5-ns) raws li ib tug spinffic Linewidth txo qis los ntawm 3.8 g, txuas ntxiv ntxiv rau hauv membrane fluidity.
Molecular txheej txheem ntawm kev ua kom tiav cov roj
DysreFulation ntawm phosphatidylcholine (PC) kev npaj cov txheej txheem ntawm PC molecules los ntawm kev tso rau hauv Lipid ntawm Lipid lwg me me thiab txhawb nqa sab saw txav.
Kev hloov pauv hauv cov roj (cholesterol) (cholesterol) (cholesterol) yog ib qho tseem ceeb regulator ntawm membrane fluidity. Acetylpromazine tej zaum yuav txo nws Orderliness los ntawm kev cuam tshuam nrog cov roj (cholesterol), yog li ua kom muaj fluality fluidity.
Kev hloov pauv ntawm mem caj dab (xws li sodium poov tshuaj tau hloov pauv ntawm cov tshuaj pleev ib ce thiab lipids raws li thiab lipids, thiab tsis ncaj txhim kho membrane fluidity.
Cim npe nrov: AcePromazine Maraste 10 mg, cov chaw muag khoom, chaw tsim khoom, Hoobkas, lag luam wholesale, yuav, nqe, loj, loj, rau muag