Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm 3-dimethylaminophenol cas 99-07-0 nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo 3-dimethylaminophenol cas 99-07-0 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
3- Dimethylaminophenol, koob siv lead ua, flash point 184 degree. Soluble hauv ethanol, ether, benzene, acetone, alkali thiab inorganic acid, yuav luag insoluble hauv dej. Cov khoom no tuaj yeem siv los ua ib qho nruab nrab ntawm neostigmine bromide thiab anthrone dyes, nrog rau cov xim nruab nrab ntawm cov xim liab, kua qaub txiv duaj liab, alkaline stamens aroma liab. Nws tshwm nyob rau hauv daim ntawv ntawm dawb mus rau lub teeb daj crystalline hmoov. Ib qho yooj yim rau decompose, nws tsis muaj qhov pom tseeb ntawm qhov kub thiab txias ntawm tus qauv atmospheric siab. Thaum rhuab, nws yuav decompose thiab tso tawm cov pa phem. Nws muaj qee yam solubility hauv dej. Nyob rau hauv chav tsev kub, nws yog soluble nyob rau hauv dej thiab tsim cov xim tsis muaj xim los yog daj me ntsis. Tsis tas li ntawd, nws tseem tuaj yeem yaj hauv ntau cov kuab tshuaj organic, xws li ethanol, acetone, thiab cyclohexane.
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Tshuaj Formula |
C8H11 Nr |
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Exact Mass |
137.08 |
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Molecular Luj |
137.18 |
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m/z |
137.08 (100.0%), 138.09 (8.7%) |
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Elemental Analysis |
C, 70.04; H, 8.08; N, 10.21; O, 11.66 |
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Melting Point |
82-84℃(lit.) |
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Boiling Point |
265-268 ° C |
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Qhov ntom |
1.0976 (zeeg) |
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Refractive Index |
1.5895 (kwv yees) |
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Flash Point |
148 degree |
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Kev cia khoom |
Khaws nyob rau hauv qhov chaw tsaus, inert cua, chav tsev kub |
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Solubility |
Soluble hauv DMSO (me ntsis), methanol (me ntsis) |
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Acidity Coefficient (pKa) |
10.06 ± 0.10 (Kev kwv yees) |
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Tus nqi PH |
7 (10g / l, H2O, 20 degree) (slurry) |
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Dej Solubility |
SIB HLUB |
Lub refractive index nyob ntawm wavelength thiab kub. Feem ntau hais lus, nws qhov refractive index nce nrog qhov txo qis hauv wavelength. Ntawm qhov sib txawv wavelengths (xws li 589.3 nanometers), nws qhov taw qhia qhov taw qhia yog kwv yees li 1.594. Nws yog ib qho tsis muaj zog alkaline compound. Thaum yaj hauv dej, nws tsim cov dimethylaminophenol ions thiab ua rau cov kev daws teeb meem tshwm sim alkaline. Yog li ntawd, nws tus nqi pH feem ntau yog siab dua 7, nyob ntawm qhov kev daws teeb meem. Nyob rau hauv qhov kev txiav txim ntawm lub teeb, kub siab, thiab oxidants, nws yuav tsis ruaj tsis khov thiab nquag muaj tshuaj tiv thaiv los yog decomposition. Yog li ntawd, thaum khaws cia thiab siv, nws yog ib qho tsim nyog yuav tsum tau ua tib zoo saib xyuas kom tsis txhob muaj teeb pom kev zoo thiab raug rau qhov tsis zoo ib puag ncig.
Nws tuaj yeem siv tau los ua ke cov tshuaj Neostigmine Bromide, ib qho tshuaj nrog cov tshuaj anticholinesterase uas muaj cov ntaub ntawv kho mob tseem ceeb. Hauv qab no yog cov lus piav qhia ntxaws ntxaws ntawm neostigmine bromide thiab nws cov khoom siv hluavtaws3-dimethylaminophenol:
Neostigmine Bromide
Neostigmine bromide yog ib qho kev thim rov qab acetylcholinesterase inhibitor thiab kuj yog tshuaj sympathomimetic. Nws siv cov teebmeem cholinomimetic los ntawm inhibiting cholinesterase kev ua kom acetylcholine tsis tuaj yeem hydrolyzed. Cov tshuaj no txhim kho kev tso tawm ntawm acetylcholine los ntawm presynaptic daim nyias nyias thiab txhawb nqa cov leeg pob txha, yog li txhim kho cov tsos mob ntawm cov leeg tsis muaj zog. Hauv kev xyaum kho mob, Neostigmine Bromide feem ntau yog siv los kho myasthenia gravis, ua haujlwm tom qab- phais plab hnyuv plab thiab tso zis. Tsis tas li ntawd, nws muaj qee yam bronchodilator nyhuv, uas tuaj yeem txo qhov ua pa tsis ua pa thiab txo qis dyspnea.
Lub luag hauj lwm ntawm nws nyob rau hauv lub synthesis ntawm neostigmine bromide
Raws li ib qho tseem ceeb nruab nrab ntawm cov synthesis ntawm neostigmine bromide, Qhov no koom nrog hauv cov txheej txheem synthesis ntawm cov tshuaj. Thaum lub sij hawm txheej txheem synthesis, nws nkag mus rau cov tshuaj tiv thaiv nrog lwm cov tebchaw los tsim neostigmine bromide molecules nrog cov qauv tshwj xeeb thiab cov khoom. Cov tshuaj tiv thaiv no tuaj yeem suav nrog kev hloov pauv, cov tshuaj tiv thaiv ntxiv lossis cov tshuaj tiv thaiv condensation, thiab lwm yam, nyob ntawm seb qhov kev xaiv ntawm cov txheej txheem hluavtaws.Thiab kev siv tshuaj kho mob ntawm neostigmine bromide.
Myasthenia gravis: Neostigmine bromide tuaj yeem txhim kho cov tsos mob ntawm myasthenia gravis thiab txhim kho lub neej zoo ntawm cov neeg mob.
Tom qab- phais kev ua haujlwm ntawm plab hnyuv flatulence: Los ntawm kev txhawb nqa kev sib cog lus ntawm txoj hnyuv du, neostigmine bromide tuaj yeem pab txo cov plab hnyuv plab uas tshwm sim los ntawm kev ua haujlwm tsis zoo ntawm txoj hnyuv tom qab kev phais.
Kev tso zis tso zis: Neostigmine Bromide tuaj yeem txhim kho lub zog ntawm lub zais zis yuam cov leeg urinary, uas pab txo qis cov tsos mob ntawm qhov tso zis.
● Kev ceev faj
Txawm hais tias Neostigmine Bromide muaj cov teebmeem tseem ceeb hauv kev kho mob, cov kev ceev faj hauv qab no yuav tsum tau ua thaum siv:
Saib xyuas cov kev mob tshwm sim:
Thaum siv Neostigmine Bromide, cov neeg mob yuav tsum tau saib xyuas cov kev mob tshwm sim xws li cov tub ntxhais kawm qis thiab tawm hws ntau ntxiv, thiab ceeb toom rau tus kws kho mob tam sim ntawd.
Diagnostic cuam tshuam:
Neostigmine Bromide tuaj yeem ua rau mob plab lossis mob plab, yog li yuav tsum tau them nyiaj tshwj xeeb rau kev soj ntsuam cov tsos mob thaum noj nws.
Contraindications:
Neostigmine Bromide yuav tsum tau siv nrog ceev faj los yog contraindicated nyob rau hauv tej yam kev mob, xws li tag nrho cov hlab ntsha los yog li qub ntawm lub plab.
Hauv cov ntsiab lus,3-dimethylaminophenol, ua ib qho tseem ceeb nruab nrab hauv kev sib txuas ntawm neostigmine bromide, plays lub luag haujlwm tseem ceeb hauv kev sib txuas thiab kev kho mob ntawm cov tshuaj. Raws li ib tug tshuaj nrog anticholinesterase kev ua si, neostigmine bromide yog dav siv nyob rau hauv kev kho mob ntawm myasthenia gravis thiab lwm yam kab mob, uas coj xov xwm zoo rau cov neeg mob.
Synthesis method
Ntxiv 45g m-aminophenol, 93g methyl acrylate thiab 19g acetic acid rau hauv 250ml plaub lub qhov ncauj hwj nrog lub tov khoom thiab tus pas ntsuas kub, thiab ntxiv 0.8g hydroquinone thiab 2.2g zinc chloride ua catalyst; Tig lub cev muaj zog thiab do rau 15 feeb, tom qab ntawd maj mam nce qhov kub ntawm 80 ~ 85, thiab lub sijhawm cua sov yog li 2 teev; Tom qab cua sov, txuas ntxiv kom qhov kub ntawm qhov ntsuas kub no rau cov tshuaj tiv thaiv. Tom qab 9 teev ntawm rwb thaiv tsev, coj cov qauv thiab ntsuas qhov kawg ntawm cov tshuaj tiv thaiv nrog siab -siab kua chromatograph. Thaum lub purity ntawm cov khoom mus txog ntau tshaj 92%, cov tshuaj tiv thaiv kawg taw tes yuav tuaj txog. Txwv tsis pub, txuas ntxiv kom kub kom txog thaum lub purity tsim nyog; Tom qab purity yog tsim nyog, txo qhov kub thiab txias rau 50 thiab pib nqus distillation. Tos kom qhov kub thiab txias nce mus txog 80 ~ 85 kom txog thaum tsis muaj cov distillates yog qhov kawg taw tes; Lub tiav lawm 3-hydroxy-n, N-dimethylaniline yog tau thaum kawg ntawm distillation.
Synthesis ntawm 2-Nitrophenol
Ntxiv nitrobenzene thiab concentrated sulfuric acid rau cov tshuaj tiv thaiv lub khob, do thiab sib tov.
01
Ua kom sov cov tshuaj tiv thaiv sib xyaw kom haum rau qhov kub thiab txias rau ib lub sijhawm.
02
Txias cov tshuaj tiv thaiv sib tov thiab dilute nrog dej.
03
Ua kua qaub-base neutralization los tsim 2-Nitrophenol.
04
Kev txo qis ntawm 2-Nitrophenol
Dissolve 2-Nitrophenol hauv cov kuab tshuaj tsim nyog.
01
Ntxiv qhov tsim nyog ntawm tus neeg sawv cev txo qis, xws li zinc hmoov lossis ferrous ntsev.
02
Txo cov tshuaj tiv thaiv ntawm qhov ntsuas kub kom tsim nyog feem ntau yuav tsum tswj cov tshuaj tiv thaiv tus nqi.
03
Lim kom tau txais cov khoom txo qis.
04
Synthesis ntawm3- Dimethylaminophenol
Dissolve 2-Nitrophenol hauv cov kuab tshuaj tsim nyog.
01
Ntxiv ntau Dimethylamine thiab ua kom sov cov tshuaj tiv thaiv sib tov.
02
Teb rau ntawm qhov ntsuas kub uas tsim nyog, xws li siv cov tshuaj tiv thaiv reflux.
03
Tom qab ua tiav cov tshuaj tiv thaiv, txias qhov sib tov thiab lim cov precipitate.
04
Tau cov khoom los ntawm crystallization los yog lwm txoj kev purification.
05
Tshuaj pleev ib ce:
Nws kuj tseem tuaj yeem siv rau hauv kev lag luam tshuaj pleev ib ce, feem ntau yog cov khoom muaj txiaj ntsig nrog antioxidant thiab tiv thaiv kev laus -. Nws tuaj yeem siv los npaj cov khoom tu tawv nqaij ntawm lub ntsej muag, cov khoom tu plaub hau, thiab pleev.
Chemical intermediates:
Nws yog ib qho tseem ceeb nruab nrab ntawm ntau cov organic synthesis tshuaj. Nws tuaj yeem siv los ua cov khoom ua ntej rau dyes, fluorescent agents, thiab photosensitive compounds. Los ntawm kev qhia cov pab pawg ua haujlwm sib txawv ntawm cov khoom, ntau cov khoom sib txuas nrog cov khoom tshwj xeeb thiab cov ntawv thov tuaj yeem ua ke.
Dyes thiab colorants:
Nws tuaj yeem siv los ua raw khoom rau dyes thiab colorants. Nws cov qauv thiab cov yam ntxwv ua rau nws siv dav hauv kev lag luam dyeing. Piv txwv li, nws tuaj yeem siv los npaj cov khoom xws li pigments, dye inks, thiab colorants.
Pharmaceutical teb:
Nws kuj muaj qee qhov kev siv hauv kev lag luam tshuaj. Vim nws cov tshuaj tiv thaiv antioxidant thiab tiv thaiv - cov khoom ua rau mob, nws tuaj yeem siv los ua cov khoom siv raw rau qee yam tshuaj. Tsis tas li ntawd, nws kuj tuaj yeem siv los ua ke qee qhov Analgesic thiab hauv zos Narcotic.
Electrochemical teb:
Vim nws cov khoom zoo heev redox, Nws tuaj yeem siv rau hauv thaj chaw ntawm electrochemistry. Nws tuaj yeem siv los ua cov khoom siv anode lossis koom nrog cov tshuaj tiv thaiv electrochemical hauv lwm txoj kev. Tsis tas li ntawd, nws tseem tuaj yeem siv los npaj cov khoom siv hluav taws xob hauv cov khoom siv hluav taws xob.
Photosensitizer:
Nws yog ib qho uas nquag siv photosensitizer uas tuaj yeem siv rau hauv kev yees duab thiab luam ntawv. Nws tuaj yeem tsim cov tshuaj lom neeg hauv cov ntaub ntawv photosensitive thiab siv los npaj cov khoom xws li cov duab thaij duab, luam ntawv zaj duab xis, thiab ntawv photosensitive.
Antioxidants:
Nws muaj zog antioxidant zog thiab tuaj yeem siv los ua antioxidant hauv kev lag luam roj hmab thiab yas. Nws tuaj yeem ncua cov txheej txheem kev laus thiab degradation ntawm polymers, txhim kho kev ruaj ntseg thiab kev pabcuam lub neej ntawm cov ntaub ntawv.
Antioxidant Properties: nws tau pom tias muaj peev xwm antioxidant, uas ua rau nws tshem tawm cov dawb radicals thiab tiv thaiv cov hlwb los ntawm oxidative kev nyuaj siab. Cov cuab yeej no yog qhov tseem ceeb hauv kev tiv thaiv cellular puas thiab cov txheej txheem kev laus.
Hair Dyeing Agent: Daim ntawv thov tseem ceeb tshaj plaws ntawm 3-DMAP yog los ntawm nws txoj kev siv los ua ib qho tseem ceeb hauv kev sib txuas ntawm cov plaub hau oxidative, tshwj xeeb tshaj yog cov plaub hau dyes. Nws reacts nrog oxidizing tus neeg sawv cev zoo li hydrogen peroxide los tsim cov xim intermediates uas tso rau cov plaub hau fibers, muab cov xim ntev.
Muaj peev xwm Antimicrobial Activity: Txawm hais tias tsis tau kawm ntau, qee qhov kev tshawb fawb qhia tias 3-DMAP thiab nws cov derivatives tuaj yeem pom cov tshuaj tua kab mob tiv thaiv qee yam kab mob thiab cov kab mob fungal. Qhov no tuaj yeem ua rau cov ntawv thov tshiab hauv cov tshuaj tua kab mob lossis cov tshuaj tua kab mob.
Daim ntawv thov
Kev yees duab
Nws muaj ib daim ntawv thov tseem ceeb hauv kev yees duab ua tus tsim tawm. Hauv cov xim dub - thiab - cov duab thaij duab dawb, cov neeg tsim khoom yog cov tshuaj uas txo cov nyiaj halide crystals nyob rau hauv cov duab thaij duab los yog ntawv rau xim hlau nyiaj, tsim cov duab pom. Qhov no ua raws li tus neeg sawv cev tsim tawm vim nws muaj peev xwm pub dawb electrons thiab txo cov nyiaj ions. Nws muaj qee qhov zoo hauv kev txhim kho kev yees duab, xws li muab cov duab zoo sib xws thiab ua kom pom tseeb. Nws tuaj yeem siv ib leeg lossis ua ke nrog lwm tus neeg tsim khoom kom ua tiav cov teebmeem tshwj xeeb.
Kev lag luam kws tshuaj
Hauv kev lag luam kws tshuaj, qhov no thiab nws cov derivatives yog siv los ua intermediates hauv kev sib txuas ntawm ntau yam tshuaj. Lub xub ntiag ntawm phenol thiab dimethylamino ua haujlwm pab pawg ua rau nws muaj ntau lub tsev thaiv rau kev tsim kho cov tshuaj molecules ntau dua. Piv txwv li, nws tuaj yeem siv los qhia cov pab pawg tshwj xeeb lossis hloov kho cov qauv ntawm cov neeg sib tw tshuaj uas twb muaj lawm los txhim kho lawv cov khoom siv tshuaj, xws li bioavailability, solubility, thiab kev ua haujlwm. Qee cov derivatives ntawm nws tej zaum yuav muaj kev ua ub no ntawm lawv tus kheej, xws li tshuaj tua kab mob los yog tshuaj tiv thaiv - inflammatory zog, txawm hais tias kev tshawb fawb ntxiv feem ntau yuav tsum tau tshawb nrhiav thiab tsim cov kev siv tshuaj kho mob.
Dye Industry
Qhov no kuj yog siv nyob rau hauv lub synthesis ntawm dyes. Nws tuaj yeem cuam tshuam nrog ntau yam chromophores thiab auxochromes los tsim cov xim sib xyaw. Cov hluav taws xob - pub thiab tshem tawm cov khoom ntawm dimethylamino thiab hydroxyl pawg, raws li, tuaj yeem cuam tshuam rau kev nqus thiab emission spectra ntawm cov dyes tshwm sim. Cov dyes no pom cov ntawv thov hauv textiles, ntawv, thiab lwm yam kev lag luam uas yuav tsum muaj xim.
Analytical Chemistry
Nyob rau hauv analytical chemistry, nws tuaj yeem siv los ua ib qho reagent rau kev tshawb nrhiav thiab kev txiav txim siab ntawm qee yam hlau ions. Nws tsim cov xim pleev xim nrog qee cov hlau ions, xws li hlau (III) thiab molybdenum (VI). Cov xim ntawm cov complex tuaj yeem ntsuas tau siv cov txheej txheem spectrophotometric, tso cai rau kev txheeb xyuas ntau ntawm cov hlau ions hauv cov qauv.
Los ntawm kev ua haujlwm ua tus tsim duab zoo rau kev ua yeeb yam tseem ceeb hauv kev lag luam kws tshuaj thiab cov xim tseem ceeb- ua tus neeg sawv cev hauv cov xim zas, nws ua rau pom qhov muaj txiaj ntsig zoo thiab muaj txiaj ntsig zoo. Nws koom nrog cov tshuaj tiv thaiv tseem ceeb xws li kev sib txuas, oxidation, thiab condensation, txhawb kev tsim cov tshuaj zoo, cov khoom siv ua haujlwm, thiab kev kho mob nruab nrab. Txawm li cas los xij, kev saib xyuas yuav tsum tau them rau nws cov yam ntxwv kev nyab xeeb.
Kev ua haujlwm tsis raug, khaws cia, lossis tso tawm tuaj yeem ua rau tawv nqaij khaus, ua pa tsis zoo, lossis muaj kuab paug ib puag ncig. Yog li ntawd, kev ua raws li cov lus qhia tshwj xeeb, kev tiv thaiv kev tiv thaiv, thiab cov kev cai pov tseg pov tseg yog qhov tseem ceeb.
Los ntawm kev paub txog nws cov khoom siv physicochemical, kev siv cov txheej txheem, thiab cov txheej txheem kev nyab xeeb, cov kws tshawb fawb thiab cov kws kho mob tuaj yeem ua kom muaj txiaj ntsig zoo ntawm 3-dimethylaminophenol, ua tiav cov txheej txheem thiab tswj tau cov ntawv thov, thiab xyuas kom nws muaj txiaj ntsig, nyab xeeb, thiab siv tau zoo hauv kev tsim khoom niaj hnub thiab kev tshawb fawb. Qhov no yog ib qho kev sib xyaw nrog kev sib xyaw tshwj xeeb ntawm cov khoom siv tshuaj thiab lub cev uas ua rau nws muaj txiaj ntsig zoo thoob plaws ntau hom kev lag luam. Nws txoj kev ua kom paub tab thiab tswj tau ua kom muaj kev ruaj ntseg ntau lawm, ua kom muaj kev ntseeg siab rau kev lag luam loj hauv kev lag luam thaum tswj xyuas cov khoom zoo ib yam. Nws cov tshuaj tiv thaiv zoo heev thiab cov qauv kev ruaj ntseg kuj ua rau lub hauv paus ruaj khov rau nws qhov kev ua tau zoo hauv cov tshuaj zawv plaub hau, tshuaj, thiab cov khoom siv yees duab, ntxiv dag zog rau nws daim ntawv thov muaj peev xwm thiab kev sib tw ua lag luam.
Cim npe nrov: 3-dimethylaminophenol CAS 99-07-0, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom