Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam thiab cov chaw muag khoom ntawm ETHACRIDINE lactate li 6402-23-9 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale ntau txoj kev ua tau zoo ethacritine lactate cas 6402-23-9 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Ethacridine lactate monohydrate, tshuaj lom neeg npe [(e)- 1,4,6-tetrahydro-2-eethylica acid 2- (Diethylamino) Cov Qauv Txuj Ci Zoo, Molecular Cov Qauv C18H2H2N3N3O4, CAS 6402-23-9, zoo li hmoov dawb crystalline. Qhov no crystalloinity yog vim lub kaw lus ze ntawm cov lwg me me los ntawm hydrogen bonds, van der waals rog, thiab lwm yam kev sib txuam, tsim cov qauv siv lead ua. Tus qauv tsim crystal no muab nws ruaj ruaj ruaj khov thiab lub tshuab hluav taws xob qis hauv lub xeev ruaj khov. Muaj dej so kom zoo. Vim muaj ntau pawg neeg sab nrauv hauv nws cov molecule, xws li pab pawg hydroxyl thiab cov pab pawg no tuaj yeem tsim cov lwg dej, yog li txhawb cov kab hauv dej. Siv nyob rau hauv cov teb ntawm tib neeg, tsiaj, kev ua liaj ua teb thiab kev kho tsiaj thiab kho kab mob thiab kab mob uas tshwm sim los ntawm cab nematodes. Raws li qhov sib xyaw nrog ntau cov ntawv thov, nws muaj cov ntawv thov tseem ceeb hauv cov tshuaj, kev tshawb fawb, kev lag luam, thiab lwm thaj chaw.
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Tshuaj Cov Qauv |
C18H21N3O4 |
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Muaj pes tsawg leej |
343 |
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Molecular hnyav |
353 |
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m/z |
343 (100.0%), 344 (19.5%), 345 (1.8%), 344 |
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Kev Ntsuam Xyuas |
C, 62.96; H, 6.16; N, 12.24; O, 18.64 |
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Lactic acid ethacridine monohydrate is a compound with lactic acid ethacridine as the core component, widely used in medical, industrial, and scientific research fields. Hauv qab no muab cov lus qhia ntxaws ntxaws ntawm nws lub hom phiaj los ntawm kev tshaj lij kev tshaj lij:
1. Kev tua kab mob ntawm daim tawv nqaij thiab cov tawv nqaij ua plaub hau
Lactic acid etharate exert cov kab mob zoo (xws li Staphyncov Areus thiab Streptococcus) thiab ob peb gram cov kab mob tsis zoo.
Daim Ntawv Thov:
Huv si thiab kho hlawv, scald, thiab kev mob siab kom tiv thaiv kev kis tus mob thiab kho kom zoo.
Cov tshuaj tua kab mob hauv zos ua ntej kev phais mob los txo qis kev pheej hmoo kis tus kab mob.
Kev kho mob ntawm qhov ncauj ntawm qhov ncauj thiab mob encosal, gingivitis, thiab particontitis, siv ntub dej taws lossis cov tshuaj yaug qhov ncauj.
Mechanism ntawm kev nqis tes ua: cuam tshuam cov qauv ntawm cov kab mob cell nyias nyias, inhibits protein synthesis, thiab yog li block cov kab mob proteation.
2. Kab Mob Raug Mob
Haum rau kev kis mob skick (xws li boils, abscesses, purulent ntawm cov kab mob ntawm cov kab mob) thiab tshem tawm cov kab mob ulcerated.
Txoj Kev Kho Mob:
Ntws ntub: Npog lub qhov txhab nrog cov kab mob nrog cov ntaub nyias nyias nyob rau hauv cov tshuaj, 2-3 zaug ib hnub twg rau 20-30 feeb txhua lub sijhawm, kom tshem tawm cov turulent cov kuab thiab kom txo cov pa.
Yaug: rau qhov txhab loj dua lossis kab mob kab noj hniav, yaug ncaj qha nrog kev daws teeb meem.
Cov kev soj ntsuam cov txiaj ntsig: kev tshawb fawb pom tau hais tias kev siv lactic acid etharate los kho qhov txhab kis tau (nruab nrab 3-5 hnub) thiab txo qhov kev pheej hmoo ntawm caws pliav txaus ntshai.
3. Kev kho mob ntawm gynecological kab mob
Nyob rau hauv teb ntawm gynecology, lactic acid ethacrate yog feem ntau siv rau qhov chaw tso quav ntawm qhov muag tsis zoo los kho cov kab mob ntawm qhov muag tsis zoo, kev mob khaub thuas thiab lwm yam kab mob.
Mechanism ntawm kev ua: los ntawm inhibiting txoj kev loj hlob ntawm pathogens nyob rau hauv lub paum (xws li Gardnerella thiab Candida Albicans), nws txhim kho cov kab ntawv ntawm lub paum ntawm lub paum), nws txhim kho cov kab ntawv ntawm lub paum ntawm lub paum)
Kev siv: Dilute cov kev daws teeb meem (feem ntau yog nyob rau hauv 1:10 piv) thiab yaug lub chaw mos ib zaug ib hnub rau 7-10 hnub.
Cov ntaub ntawv hauv tsev kho mob: Kev tshawb fawb txog 200 tus neeg mob ntawm tus kws kho mob muaj kev kho mob ntawm 85%, siab dua li pawg tswj (60%).
4. Induced rho nyiaj hauv nruab nrab - cev cev xeeb tub
Inraamniotic txhaj tshuaj ntawmEthacridine lactate monohydratePuas yog ib txoj kev siv rau kev ua haujlwm hauv plab hauv nruab nrab cev xeeb tub (14-28 lub lim tiam).
Mechanism ntawm kev ua: cov tshuaj ua rau muaj kev cog lus ntawm cov leeg nqaij cov leeg, txhawb nqa kev ntiab tawm ntawm qhov chaw tso quav thiab menyuam hauv plab.
Cov Qauv Kev Ua Haujlwm: Nws yuav tsum tau nqa tawm hauv cov tsev kho mob tsim nyog, nruj ua raws li lub hauv paus ntsiab lus ntawm Aseptic ua haujlwm, thiab kev txhaj tshuaj muaj feem ntau 100mg.
Kev kuaj xyuas cov txiaj ntsig: thaum siv ua ke nrog Mifepristone, xws li cov kev ua tiav ntawm kev ua kom raug 95%, thiab cov kev sib xyaw rau uterine tawg) yog qis dua li cov txheej txheem ib txwm muaj.
5. Kev Kho Mob Txiaj Ntsig rau Cov Kab Mob Ophthhalmic
Yuav siv tau los yaug lub hom phiaj thiab kev kis qhov muag qhov muag xws li kev mob nkeeg thiab bleephalitis.
Kev siv: Siv cov paj rwb muab tso rau hauv cov tshuaj so los so lub hnab sib txawv, lossis nrog cov lus daws 3-4 zaug ib hnub.
Ceev faj: Zam kev sib cuag ncaj qha ntawm kev daws nrog lub pob zeb los tiv thaiv kev voos voos.
1. Tshuaj Nruab Nrab
Lactic Acid etharate tuaj yeem siv ua ib nrab rau cov khoom siv tshuaj xws li dyes, pigments, inks, thiab lwm yam.
Cov tshuaj tiv thaiv cov tshuaj tiv thaiv: Cov tshuaj tiv thaiv yuav tsum tau ua raws li kev tiv thaiv cov roj hauv qis qis ntawm cov chav sov qis (-20℃kom tsis txhob muaj cov oxidative degradation.
Cov ntaub ntawv thov daim ntawv thov: Siv rau synthesizing indole ua kom zoo li hloov kho rau cov khoom siv polymer kom txhim kho lawv cov huab cua tsis kam ua lawv cov huab cua tsis kam.
2. Biotechnology Raw Khoom Siv
Nyob rau hauv enzyme catalyzed kev tawm tsam, lactate etharate tuaj yeem ua raws li substrate lossis cofactor thiab koom nrog hauv kev tshwj xeeb biosynthetic txoj kev.
Kev Tshawb Fawb Kev Kawm: Qee lub chaw soj ntsuam tau sim siv nws los ua ke cov khoom lag luam zoo nkauj (xws li vitamin k derivatives), tab sis kev lag luam ntau lawm tseem tsis tau ua tiav.
Kev sib tw technical: Yuav tsum daws cov teeb meem xws li kev xaiv cov tshuaj tiv thaiv tsawg thiab kev sib cais nyuaj.
3. Kev lag luam tshuaj tua kab mob
Muaj kev huv ntau huv (ntau dua lossis sib npaug nrog 99%) Lactic Acid Ethacrate tuaj yeem siv rau kev kho mob ntawm cov cuab yeej siv thiab cov raj xa dej.
Cov txiaj ntsig zoo: tsis yog kev xeb rau cov khoom siv hlau thiab yooj yim los ntxuav cov khoom noj yooj yim.
Kev Siv Cov Xwm Txheej: Kev Tiv Thaiv Ntawm Cov Khoom Siv Ntau Lawm hauv kev ua zaub mov thiab cov tshuaj lag luam.
1. Kev tshawb fawb microbiological
Lactic acid etharate tuaj yeem siv los ua tus neeg sawv cev antibacterial rau kev kawm cov tshuab ntawm cov kab mob tsis kam.
Kev tsim qauv tsim: Kev tshuaj ntsuam cov kev tiv thaiv kev tiv thaiv los ntawm kev ntsuas qhov cuam tshuam ntawm cov tshuaj sib txawv ntawm cov tshuaj tua kab mob.
Kev tshawb nrhiav qhov tseem ceeb: kom muab lub hauv paus rau kev txhim kho cov tshuaj tua kab mob tshiab.
2. Kev tshawb fawb Biology
Hauv kev coj noj coj ua ntawm tes, lactate etharate tuaj yeem siv los sim ua kom muaj kev ntxhov siab ntawm oxidative ib puag ncig thiab kev kawm txog kev kuaj mob ntawm tes.
Kev sim ua qauv: Ntxiv cov tshuaj rau cov kab lis kev cai nruab nrab thiab ntes ntawm lub cell Apoptosis tus nqi los ntawm nus cytimetry.
Cov ntaub ntawv thov daim ntawv thov: Siv los kawm txog kev sib raug zoo ntawm neuronal oxidative kev puas tsuaj thiab Parkinson tus kab mob.
3. Cov Qauv Kev Tsim Tshuaj
Raws li impurity siv cov tshuaj, lactic acid ethacrate yog siv los ntsuas tshuaj pleev ib ce xws li HPLC thiab GC, thiab ntsuas cov tshuaj tswj kom zoo.
Cov chaw muag khoom: Shanghai Baiishun Biotechnology Co., Ltd., Xinhongli Tshuaj, thiab lwm yam.
Cov Txheej Txheem Zoo: Yuav tsum ua raws li cov tseev kom muaj feem xyuam nrog cov tshuaj suav ntawm lub ntsej muag (CHP) lossis European Pharmacopoeia (EP).
Ethacridine lactate monohydrateyog qhov sib txuas ua ke dav hauv thaj chaw, uas muaj ntau yam khoom siv hluav taws xob, suav nrog anti {} {{{incammatory cuam tshuam. Peb yuav piav qhia nyob rau hauv kev nthuav dav tag nrho cov xwm txheej hluavtaws ntawm cov khoom lag luam.
1. Noj anthracene raws li cov txheej txheem hluavtaws ntawm raw khoom:
Qhov ntxov tshaj plaws cov qauv squthesis ntawm nws yog siv anthracene raws li cov khoom pib, thiab tau txais cov khoom lag luam los ntawm ntau {{}} kauj ruam kev tiv thaiv. Cov hauv qab no yog cov ncauj lus kom ntxaws ntawm hom no:
(1) Chlorination Trainion:
Rov qab ua tsis taus nrog ferric chloride thiab oxidize nws nyob rau hauv Alkaline cov mob los tsim 2-amino-9-chloromethylranthylacene.
(2) nitration cov tshuaj tiv thaiv:
Nitrate 2-amino-9-chloromethylranthracene nrog nitric acid nyob rau hauv catalysis ntawm sulfuric acid kom tau 2-amino-9-nitromethylranthracene.
(3) kev tawm tsam txo:
2-amino-9-nitromethylanthracene raug txo los ntawm sodium sulfite los tsim 2-amino-9-aminomethylranthracene.
(4) Cov tshuaj tiv thaiv hws:
Condense 2 {{5 5} Aminomethylranthracene thiab lactic acidracen thiab lactic acid nyob rau hauv acidic tej yam kev mob kom tau 2- (9-acetoxy-2-aminomethylacenylacenylacenylacenylacenylacenylacenylacenylacenylaceny
(5) Kev Tiv Thaiv Hydrolysis:
RECH 2 - (9-acetoxy-2-aminomethylacenylacen) -lium carbonate raws li hydrolygy carbonate xws li hydrolysis ua kom muaj kev mob ethacridine.
(6) Crystallization thiab tshem tawm dej:
Ethacridine lactate yog rhuab thiab crystallized nyob rau hauv cov kev daws teeb meem, thiab cov dej hauv lub crystal tau muab tshem tawm kom tau txais cov khoom. Cov lus tshaj tawm ntawm cov qauv no yog li 15%.
2. Noj 1,3-dichloroacetone raws li cov txheej txheem hluavtaws ntawm raw khoom:
Nrog kev txhim kho kev kawm txuas ntxiv ntawm kev tshawb fawb thiab thev naus laus zis, cov neeg tau maj mam nrhiav rau cov khoom siv hluavtthesis ntau dua. Ib txoj kev siv tau siv 1,3 {- dichloroacetone ua cov khoom siv raw kom tau txais cov khoom lag luam los ntawm ntau kauj ruam ntawm cov khoom siv ntau. Cov hauv qab no yog cov ncauj lus kom ntxaws ntawm hom no:
(1) Hydroxylation Cov:
REI 1,3-dichloroacetone nrog phenol hauv ethanol / sodium hydroxide tov kom tau txais 3-hydroxy-2-pyRuvate.
(2) Cov tshuaj tiv thaiv hws:
Condense 3-hydroxy-2-pyRUVic acid thiab acetyl chloride nyob rau hauv cov kab ke los tsim tsim 3- (acetoxy) -2-hydroxypropionic acid.
(3) Cov Lus Tiv Thaiv Tsis Txaus Siab:
Aromize 3- (acetoxy) -2-hydroxy) -2-hydroxyPropionic acid thiab muaj cov phosphorus pentoxide kom tau 3- (Bromophenyl) -2-acetoxy glycerin.
(4) cov tshuaj tiv thaiv rov qab:
Rov Kho 3- Bromophenyl) -2-acetoxyPropionic acid thiab sodium bisulfite hauv ethanol daws kom tsim tau 3- (pyridin-2-yl) -2-prot acid.
(5) Cov tshuaj tiv thaiv hws:
Condense 3- (pyridin-2-yl) -2-pyruvate thiab acetic acid chloride nyob rau hauv alkaline tej yam kev mob los tsim cov kab mob etharidine kom tsim kev ua haujlwm.
(6) Crystallization thiab tshem tawm dej:
Ethacridine lactate yog rhuab thiab crystallized nyob rau hauv cov kev daws teeb meem, thiab cov dej hauv lub crystal tau muab tshem tawm kom tau txais cov khoom. Cov lus tshaj tawm ntawm cov qauv no yog li 20%.
Hauv ib lo lus, cov saum toj no yog lub ntsiab synthesis txoj kev ntawm cov khoom. Txawm hais tias cov kauj ruam thiab kev khiav haujlwm ntawm cov hau kev no sib txawv, lawv tuaj yeem npaj siab ua siab zoo- zoo thiab ntshiabEthacridine lactate monohydrate, uas muab kev txhawb nqa yooj yim rau nws qhov kev thov dav hauv thaj chaw ntawm cov tshuaj.
Cim npe nrov: Ethacritine Lactate cas 6402-23-9, cov chaw muag khoom, chaw tsim khoom, chaw tsim khoom, yuav khoom, nqe, loj, rau muag