Ntshiab alpha arbutin hmoov CAS 84380-01-8

Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam thiab cov chaw muag khoom Albein hmoov zoo li cas 84380-01-8 nyob hauv Suav teb. Txais tos rau lag luam wholesale loj zoo ntshiab alpha arbutin hmoov CAS 84380-01-8 Kev muag khoom ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.

Ntshiab alpha arbutin hmoov, tseem hu ua -} arbutin, yog ib qho nqaij tawv muaj tshwm sim los ntawm cov tawv nqaij beadberry {1} {2} ursi) thiab lwm yam khoom cog. Nws yog ib qho muaj zog tsis tau maj hauv cov khoom siv kom zoo nkauj thiab tawv nqaij rau nws lub peev xwm los txo cov tsos mob ntawm hyperpigmentation, tsaus nti, thiab quav hnav.

Chemically, Alpha -}}}} Arbutin yog hom ntawm hydroquinone txuas, uas txhais tau tias nws muaj tsawg dua khib nyiab thiab muaj kev nyab xeeb dua rau kev siv ntev. Cov kab ke no ua haujlwm los ntawm kev ua haujlwm ntawm Tyrosinase, lub luag haujlwm enzyme rau kev tsim melanin, cov xim uas muab cov tawv nqaij nws cov xim. Los ntawm thaiv tyrosinase, alpha -}}}}}}}}}} Cov txheej txheem me me thiab ua rau tawv nqaij ntau dua thiab ntse.

Alpha -} Arbutin yog qhov muaj tseeb rau nws cov ruaj khov thiab kev ua tau zoo, txawm tias muaj tawv tawv. Nws yog yooj yim nqus mus rau hauv daim tawv nqaij, nkag mus rau hauv cov khaubncaws sab nraud povtseg qhov chaw melanin yog tsim tawm. Qhov kev sib tw no tob kom paub tseeb tias cov khoom xyaw ua haujlwm los ntawm kev daws teeb meem thiab tawv nqaij tsis sib xws.

Ntxiv rau nws cov tawv nqaij -}}}} -}}-}}}}}}} artension cov kev ntxhov siab thiab kev puas tsuaj los ntawm kev dawb radicals. Nws tuaj yeem pom muaj nyob hauv ntau yam khoom tawv tawv, suav nrog cov khoom noj, thiab muaj ntau yam ntxiv rau kev ua tiav kev ua kom pom tseeb, ci ntsa iab.

Zuag qhia tag nrho, alpha -} kev xaiv ntawm lawv cov tawv nqaij los ntawm kev txo cov tawv nqaij tawv nqaij ntau dua.

Alpha - arbutin tsis muaj ib txwm muaj nyob hauv ib puag ncig. Hloov chaw, nws yog synthesized los ntawm cov txheej txheem biochemical tshwj xeeb. Qhov no ua ke yog tsim los ntawm enzymatic glycosylation cov tshuaj uas cuam tshuam nrog cov kab mob sib txawv. Tshwj xeeb, nws yog tsim los ntawm kev sib txuas nrog molecule ntawm hydroquinone (los yog molecule ntawm cov piam thaj, ua rau kev tsim ib qho alula {}}} arbutin molecule. Qhov kev tawm tsam no feem ntau tshwm sim hauv cov chaw tswj cov kab mob uas tsim nyog los tsim cov enzymes tsim nyog rau cov txheej txheem glycosylation.

Thawj txoj kev kom tau txais alpha -}}}}}}}}}}} Cov txheej txheem kev tiv thaiv nrog ib puag ncig kev tiv thaiv cov qauv thiab cov khoom ua kom siab sereoselectivity. Thaum fermentation:

Ntshiab alpha arbutin hmoov, nrog nws cov tawv nqaij tshwj xeeb - Cov khoom zoo thiab kev nyab xeeb profile, tau dhau los ua cov tshuaj pleev ib ce thiab cov khoom siv tshuaj lom neeg. Nws zoo inhibits tsim ntawm melanin los ntawm suppressing tyrosinase kev ua, pab txhawb kom tawv nqaij thiab txo cov xim.

• Ntau yam hauv cov kev tshawb fawb venp tau raug ntsuas ntau yam los ntsuas qhov muaj peev xwm ntawm alpha-}}}}} Cov kev tshawb fawb no yog qhov tseem ceeb hauv kev nkag siab ntawm alpha kev ua ntawm alpha- kev siv cov khoom siv ntxuav tawv nqaij rau cov tawv nqaij ntxuav hniav dawb.
• Hauv cov kev tshawb fawb no, alpha -}}}}}}}}}}}}}}}} yog feem ntau ua kom loj hlob nrog tyrosinase nyob rau hauv kev tswj hwm. Cov kws tshawb nrhiav mam li saib xyuas cov kev hloov tom ntej hauv kev sib tw melanin lossis cov melanogenesis. Qhov no tuaj yeem ua tiav los ntawm ntau txoj hauv kev, xws li Spectrophotometric xav kom ntsuas cov ntsiab lus txo qis lossis qhov cuam tshuam ntawm Tyrosinase kev ua si ncaj qha.
• The results of these in vitro studies have consistently shown that alpha-arbutin effectively inhibits tyrosinase activity, leading to a reduction in melanin synthesis. Qhov no Inhibitos nyhuv yog koob -}}}}}}}}}}}}}}}}}}}}}}}}} kev ua haujlwm thiab melanin ntau lawm.
• Txawm li cas los xij, nws yog ib qho tseem ceeb kom nco ntsoov tias hauv cov txiaj ntsig vitro yuav tsis nco ntsoov ncaj qha txhais mus rau Vivo kev ua tau zoo. Yog li ntawd, cov kev tshawb nrhiav chaw soj ntsuam kuj tseem tsim nyog los ntsuas qhov ua tau zoo thiab kev nyab xeeb ntawm alpha {}- ntiaj teb daim ntawv thov. Nevertheless, the in vitro studies provide valuable insights into the mechanism of action of alpha-arbutin and its potential as a skin whitening agent.
• Alpha {{0-} Arbutin tau pom tias muaj kev tiv thaiv tyrosinase tyrosinase cov kev ua ub no ntawm cov kev ua kom ntau. Piv txwv li, ib txoj kev kawm tau tshaj tawm ib tus nqi IC50 μm rau alpha-}}} {{{{- 4A5 cell. Qhov no qhia tau hais tias alpha-arbutin tuaj yeem txo qis melanin ntau lawm txawm tias nyob nruab nrab ntau.

• Txhawm rau kom nkag siab ntxiv txog kev cuam tshuam ntawm alpha -}}}}}}}}}} Cov kws tshawb fawb tau tshawb xyuas nws cov synthes cell thiab cov qauv tawv nqaij.
• Alpha {{0- arbutin tau pom tias muaj txiaj ntsig melanin synthesis nyob rau koob tshuaj {}}. Nyob rau hauv tsis - Cytotoxic ntau, nws txo tyrosinase kev ua si thiab tom qab yuav txo melanin ntau lawm. These effects have been observed in both two-dimensional cell cultures and three-dimensional skin models, suggesting that alpha-arbutin can effectively lighten skin tone when applied topically.

• Cov kev tshawb fawb kev nyab xeeb feem ntau yog ntsuas cov cytotoxicity ntawm alpha- arbutin hauv ntau kab ntawm tes. Cov kev tshawb fawb no tau txheeb xyuas qhov peev xwm rau alpha-}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} Kev ua kom muaj kev phom sij rau cov hlwb sib txawv. Cov txiaj ntsig ntawm cov kev tshawb fawb no tuaj yeem pab txiav txim siab txog kev nyab xeeb li cas rau alpha- arbutin hauv cov khoom lag luam tawv nqaij tawv.
• Nyob rau hauv dav dav, alpha -}}}}}- pakic rau cov hlwb feem ntau siv hauv cov khoom lag luam tawv ncauj. Txawm li cas los xij, nws yog ib qho tseem ceeb kom nco ntsoov tias CyTotoxicity ntawm Alpha-}} Arbutin tuaj yeem sib txawv nyob ntawm hom xov tooj thiab kev sim ua haujlwm tshwj xeeb. Yog li ntawd, nws yog qhov tseem ceeb heev rau kev coj ua kev nyab xeeb kev nyab xeeb kom ntseeg tau tias qhov kev nyab xeeb ntawm alpha - arbutin hauv cov khoom lag luam tawv ncauj.

• Kev kawm tias kev coj ruaj khov yog qhov tseem ceeb rau kev ntsuas qhov haum ntawm alpha - arbutin rau kev siv hauv cov khoom lag luam tawv ncauj. Cov kev tshawb fawb no suav nrog kev ruaj ntseg ntawm alpha-}}}}}} qhov tseeb, pH, pH, thiab lub teeb ci. The results of these studies can help determine the shelf life of skincare products containing alpha-arbutin and ensure that they remain effective over time.
• Alpha -} arbutin tau pom tias muaj qee qhov xwm yeem, tab sis nws tuaj yeem txwv nyob rau hauv lwm tus. Piv txwv li, cov kev tshawb fawb tau pom tias Alpha-} Arbutin tseem nyob ruaj khov rau qhov kub ntawm 100℃stables rau hauv nruab nrab ntawm nruab nrab ntawm nruab nrab ntawm nruab nrab. Txawm li cas los xij, nws ua tsis ruaj khov nyob rau hauv huab siab pub (piv txwv li, pH 1 lossis 13) thiab tseem tuaj yeem cuam tshuam los ntawm lub teeb thiab ultraviolet iradiation.
• Txhawm rau kom muaj kev ruaj khov ntawm alpha -}}}} arbutin hauv cov khoom lag luam tawv nqaij, cov chaw tsim khoom feem ntau yog siv cov khoom lag luam uas tiv thaiv kev tiv thaiv lub teeb. Ib qho ntxiv, lawv ua kev ntsuas kev ruaj khov rau ncua sij hawm kom ntseeg tau tias cov khoom tseem ua tau zoo thiab nyab xeeb rau cov neeg siv khoom siv.

• Qee qhov kev tshawb fawb tau muab piv rau cov tshuaj thiab enzymatic stability, ntxiv rau kev ua haujlwm roj ntsha, ntawm alpha {} {{{1} {1}---
• Cov kev tshawb fawb no tau pom tias Alpha -}}}}}}} kev ua yeeb yam siab ruaj khov thiab ntau dua tyrosinase kev ua si piv txwv rau beta-} arbutin. Qhov no ua rau alpha-}}}} kev xaiv ntxim nyiam ntau rau kev siv hauv cov khoom lag luam tawv nqaij ua kom tiav cov tawv nqaij ntxuav hniav dawb.

Ntshiab alpha arbutin hmoovyog lub zog muaj zog thiab ib txwm muab cov khoom siv hluav taws xob skincare rau nws qhov tshwj xeeb ua rau muaj kev kub ntxhov thiab teeb pom kev zoo. Muab tau los ntawm cov beamberry cog, qhov no zoo dawb hmoov ua haujlwm nyob rau hauv kev sau hyperpigmentation, cov hnub nyoog me ntsis, thiab tawv nqaij tsis ncaj.

Alpha Arbutin ua haujlwm los ntawm kev ua haujlwm ntawm Tyrosinase, ib qho kev sib cav sib ceg rau kev tsim cov melanin, cov xim uas muab cov tawv nqaij nws xim. Los ntawm kev txo cov melanin tsim, nws pab kom funous tsaus nti thiab tiv thaiv cov tshiab los ntawm kev sib sau, ua rau muaj kev sib tw txawm thiab hluav taws xob ntau thiab ci ntsa iab.

Tsis zoo li lwm lwm lwm lwm lwm lwm cov tawv nqaij lub cev cov tawv nqaij, nws yog siab thiab tsim nyog rau ntev {}}}}}}}}} i} kev txob txob lossis tsis zoo. Nws cov kev ua yeeb yam ua kom muaj txiaj ntsig siab tshaj plaws nrog kev phiv tshuaj tsawg, ua rau nws nyiam tshaj plaws ntawm dermatologist thiab Skincare txaus siab ib yam nkaus.

Tsim rau hauv ntau cov khoom siv tawv tawv xws li cov quav yeeb yaj kiab, pleev xim, nws yooj yim rau cov tawv nqaij saum npoo av kom muab nws cov txiaj ntsig tob hauv cov khaubncaws sab nraud povtseg. Kev siv tsis tu ncua tuaj yeem ua rau muaj lub zog ci ntsa iab, meej dua, thiab cov tawv nqaij muaj zog ntau dua.

Ntxiv mus, nws ruaj khov thiab sib xyaw nrog lwm cov khoom xyaw ua rau nws muaj ntau yam ntxiv rau kev ua kom zoo nkauj skinfle. Txawm hais tias koj tab tom nrhiav chaw nyob cov teeb meem tshwj xeeb lossis tswj hwm ib qho txawm, radiant complexion,ntshiab alpha arbutin hmoovsawv tawm raws li kev txhim khu kev qha thiab xaiv tau zoo. Nws lub keeb kwm ntuj thiab muaj pov thawj kev ua tau zoo ua nws tsis muaj qhov sib txawv hauv kev tshawb xyuas qhov flawless, luminous tawv.

Ntshiab alpha arbutin hmoovyog glycosylated hydroquinone derivative thiab belongs rau hydroquinone glycoside chav kawm ntawm cov tebchaw. Nws molecular mis yog c₁₂h₁₆o₇, nrog txoj haujlwm hnyav molecular ntawm 272.25. Cov qauv tseem ceeb yog tsim los ntawm kev sib txuas ntawm Orthoe- hydropyrksyl pab pawg los ntawm glycosidic sib khi. Qhov kev sib tw diatstereeoisomer (nrog qhov kev sib tw sib luag ntawm Glycosidic txoj kev sib khi lus rov qab rau ntawm {}} {{{o {mob, thiab qhov ruaj khov.

Ntshiab -} arbutin hmoov zoo nkaus li tau tawm ntawm -}}}}}}}}}}}}}} Tsis muaj ntxhiab tsw lossis muaj ntxhiab tsw me me. Nws cov taw tes melting ntau npaum li cas yog 202- 208 degree. Tej zaum nws yuav decompose ntawm 185 - 195 degree} xyoo 19} {}} kub (2-8 degree) thiab ua kom qhuav ib puag ncig kom tsis txhob muaj kev nqus dej noo thiab noj. Nyob rau hauv cov nqe lus ntawm solubility, -Txoj kev ua tau yooj yim soluble hauv dej (151g / l ntawm 20 degree), thiab insoluble nyob rau hauv tsis-polar solvents xws li ether thiab chloroform. Qhov no Polar Solubility cov cuab yeej ua rau nws yooj yim sib xyaw nrog lwm cov hauv cov tshuaj pleev ib ce, tshwj xeeb tshaj yog qhia tau zoo dua nyob hauv cov xwm txheej sov (<70℃) or cold preparation conditions.

Tus lej pH ntawm -}}} Kev tswj tau nyob rau hauv thaj tsam ntawm 5.0 - 7.05.0 - 7.05.0 - 7.05.0 - 7.0} acidic rau cov cuab yeej tsis muaj zog. Cov pab pawg phenolroolyl thiab cov txiaj ntsig zoo nyob hauv nws cov molecule confering nws amphiphilic yam ntxwv, tab sis cov acidic xwm feem ntau. Txoj kev kawm ruaj khov tau pom tias {{{4 4}}}}}}}}}}, tshuaj pleev, cov kua pleev, thiab tshuaj aerosols, thiab aerosols. Piv rau {- arbutin, {{}} arbutin cov kev pov thawj ruaj khov rau lub teeb thiab kub. Piv txwv li, ntsuas qhov kev nrawm ntawm 40 degree, tus nqi ntawm nws cov txiaj ntsig tsis zoo ntawm cov kev pheej hmoo glycosidic kev pheej hmoo, txo cov kev pheej hmoo ntawm cov kev pheej hmoo ntawm cov kev pheej hmoo ntawm cov kev pheej hmoo ntawm cov kev pheej hmoo ntawm cov kev pheej hmoo glycosidic kev pheej hmoo, ua tsaug rau cov kev pheej hmoo ntawm cov kev pheej hmoo ntawm hydrolysis thiab oxidation.

Cov tub ntxhais tseem ceeb ntawm - arbutin stems los ntawm nws muaj zog inhibition ntawm tyrosinition ntawm tyrosinition ntawm tyrosinition ntawm tyrosinition ntawm Tyrosinition. Tyrosinase yog tus tseem ceeb enzyme nyob rau hauv melanin synthesis. - arbutin functions los ntawm cov txheej txheem hauv qab no:

Ncaj ncees Inhibition:Khi rau lub chaw ua haujlwm ntawm Tyrosinase, thaiv cov txheej txheem ntawm catalyzing lub concalyzing lub concineying cov kev hloov pauv ntawm l}} tyrosine mus rau dopaquinone.

Down - Kev Cai ntawm Cov Noob Expression:Inhibiting qhov kev hais tawm ntawm microlotubule -}}}}}} kev sib cais ntawm tyrosinase thiab cuam tshuam rau cov enzymes.

Teeb Liab Txoj Kev Cai:Ua kom cov chaw pw hav zoov enteracellular kos npe rau txoj kev taug kev, inhibiting txoj haujlwm ntawm MITF, yog thaiv cov melanin synthesis txoj kev.

Cov kev tshawb fawb tau pom tias {-}} tuaj yeem ua kom muaj 10,6% zoo dua li ntawd ntawm {}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} Ntxiv mus, -Arbutin tsis tsim cov tshuaj lom neeg lom xws li hydroquinone, zam kev phom sij ntawm cytotoxicity, voos thiab rhiab.

{{0- Betulinic Acid tau faib ua kev nyab xeeb los ntawm kev nyab xeeb los ntawm International Cosmetic Cov Khoom Siv Kom Zoo Nkauj (Inci). Cov European Commission ntawm cov neeg siv khoom muaj kev nyab xeeb (SCCS) pom zoo kom muaj kev nyab xeeb ntawm 2% rau {} Bet} Bet} Bethor acid hauv lub ntsej muag ntsej muag thiab 0.5% hauv cov tshuaj hauv lub cev. Nws muaj cov khoom xyaw muaj zog thiab tuaj yeem siv ua ke nrog cov vitametic (xws li feem ntau cov tshuaj pleev ib ce zoo li cov tshuaj tua kab mob zoo li methylparaben kom tiv thaiv kev tsim ntawm hydroquinone derivatives. Txuas ntxiv, {{{- Betulinic acid tsuas yog rau kev siv sab nraud thiab qhov ncauj yuav ua rau muaj kev phiv tsis zoo.

Sib nrug los ntawm ntxuav hniav dawb, cov tshuaj lom neeg ntawm - bethor acid ua rau nws hauv cov chaw hauv qab no:

 Anti {{0 {}}} Incibatory kho: inhibits qhov tso tawm ntawm cov nqaij tawv thiab nrawm ntawm daim tawv nqaij kho tom qab ultraviolet hlawv.

 Antioxidant: tshem tawm cov radicals dawb thiab qeeb me ntsis kev laus tawv nqaij.

 Hlawv thiab scald thiab scald kev tiv thaiv: raws li kev siv yeeb tshuaj tshiab, nws sai sai ua rau mob, txo qhov mob, txhawb nqa cov tshuaj kho kom zoo thiab nplooj tsis muaj nti.

 Cov Zaub Mov Xim: Ua lub ntuj xim, nws yog siv rau kev haus xim, khoom qab zib thiab lwm yam khoom noj.

Cim npe nrov: Ntshiab alpha Arbutin hmoov CAS 84380-01-8, cov chaw tsim khoom, chaw tsim khoom, chaw tsim khoom, yuav khoom, rau muag