Tetramisole hcl hmoov CAS 5086-74-8kuj hu uaTetramisole hydrochloric, feem ntau muaj nyob rau hauv daim ntawv ntawm tetramisole hydrochloride hmoov, xim, qhov muag duab ntxoov ntxoo hmoov tsos thiab tus cwj pwm: dawb mus rau milky dawb crystalline hmoov, veterinary tshuaj raw khoom. Nws yog cov hmoov dawb crystalline uas qee zaum tuaj yeem tshwm hauv lub teeb daj lossis xim liab. Nws cov tsos muaj qee qhov kev pom tseeb, thiab cov qauv siv lead ua tuaj yeem pom meej meej. Nws muaj solubility siab hauv dej thiab tuaj yeem yaj hauv ethanol thiab methanol. Ntawm chav tsev kub, txhua 1 gram ntawm Tetramisole Hydrochloride tuaj yeem yaj hauv 1ml dej. Thaum cov tshuaj no ua rau cov kua qaub thiab cov hauv paus, nag lossis daus tshwm sim. Lub refractive index yog 1.583, uas tuaj yeem siv rau kev tshawb nrhiav thiab kev txheeb xyuas cov tshuaj no. Thaum nws yaj hauv dej, nws qhov ntsuas qhov ntsuas tsis hloov pauv ntau, uas ua rau siab - ntsuas qhov tseeb thiab kuaj pom cov tshuaj hauv kev sim. Cov kws kho tsiaj thiab tib neeg cov tshuaj siv dav siv los ua tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob.
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Tshuaj Formula |
C11H13ClN2S |
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Exact Mass |
240 |
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Molecular Luj |
241 |
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m/z |
240 (100.0%), 242 (32.0%), 241 (11.9%), 242 (4.5%), 243 (3.8%), 244 (1.4%) |
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Elemental Analysis |
C, 54,88; H, 5,44; 14,72; Kuv. N, 11,64; Ib., 13.32 |
Solubility:
Tetramisole hcl hmoovmuaj solubility zoo thiab yooj yim soluble hauv polar solvents xws li dej, ethanol, chloroform, thiab benzene. Nws solubility nce nrog kub. Solubility tsis zoo nyob rau hauv uas tsis yog -polar solvents xws li roj av ether.
Melting point:
Lub melting point ntawm Tetramisole Hydrochloride yog nyob ib ncig ntawm 275 degree.
Acid-puag khoom:
Tetramisole Hydrochloride yog cov tshuaj alkaline heev uas nws cov amino ua haujlwm pab pawg tuaj yeem hnov mob nrog cov acids tsis muaj zog los tsim cov ntsev. Hauv dej, Tetramisole Hydrochloride tau txais cov tshuaj tiv thaiv hydrolysis, tsim cov amino dawb thiab electrophilic Tetramisole.
Kev ruaj ntseg:
Tetramisole Hydrochloride tuaj yeem khaws cia rau ntau xyoo yam tsis muaj kev puas tsuaj nyob rau hauv qhov chaw qhuav thiab qhov cua. Txawm li cas los xij, nyob rau hauv tshav ntuj lossis kub thiab av noo, cov tshuaj tiv thaiv decomposition tuaj yeem tshwm sim, ua rau cov tshuaj degradation thiab tsis ua haujlwm.
Oxidation-txo cov khoom:
Tetramisole Hydrochloride yog ib qho tsis muaj zog txo tus neeg sawv cev nrog lub peev xwm los txo cov hlau ions. Nws tuaj yeem cuam tshuam nrog qee cov oxidants, xws li dej bromine, dej iodine, thiab perchloric acid.
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Qhov feem ntau siv txoj kev nyob rau hauv lub synthesis ntawmtetramisole hcl hmoovyog cov tshuaj tiv thaiv ntawm imidazole methyl acetate thiab 2-chloropropionyl chloride. Cov hauv qab no yuav muab cov lus qhia ntxaws ntxaws rau txhua txoj kev sib xyaw ntawm Tetramisole Hydrochloride.
Thawj txoj kev yog cov tshuaj tiv thaiv ntawm imidazole methyl acetate nrog 2-chloropropionyl chloride, uas yog ib qho ntawm feem ntau siv hauv TH synthesis.
Cov txheej txheem yog raws li nram no:
Ua ntej, yaj methyl imidazole acetate thiab 2-chloropropionyl chloride nyob rau hauv anhydrous dimethylformamide (DMF), feem. Maj mam sib tov ob txoj kev daws teeb meem thiab do rau 10 mus rau 20 teev. Cov khoom siv tshuaj tiv thaiv yog qhov ua ntej ntawm TH -2-chloro-N, N, 2-trimethylacetylimidazole (2-Cl-MH), uas tuaj yeem cuam tshuam ntxiv los npaj TH tom qab sib cais thiab ua kom huv ntawm 2-Cl-MH. Thaum kawg, ntxiv dilute hydrochloric acid (HCl) aqueous tov kom tau TH.
Qhov thib ob txoj kev yog los teb nrog imidazoacetone thiab crotonic acid:
Cov kauj ruam tseem ceeb ntawm txoj kev no yog npaj ua ntej ntawm 2-amino-2-methyl-1-propanol (AMP) los ntawm kev txo cov tshuaj tiv thaiv nyob rau hauv lub xub ntiag ntawm imidazolacetone thiab crotonic acid; Tom qab ntawd, AMP tau raug sulfonylation cov tshuaj tiv thaiv kom tau TH.
Hauv qab no yog cov lus piav qhia ntxaws txog txhua qhov kev siv ntawmTetramisole hcl hmoov:
Tsiaj siv
Tetramisole Hydrochloride tuaj yeem siv los kho cov kab mob cordyceps hauv cov tsiaj. Cordyceps yog cov kab mob uas tuaj yeem kis tau rau ntau hom tsiaj. Kab mob Cordyceps tuaj yeem ua rau poob phaus, anemia, thiab lwm yam teeb meem kev noj qab haus huv. Tetramisole Hydrochloride tuaj yeem pab tswj cov kab mob cordyceps thiab txhawb cov tsiaj noj qab haus huv.
Tsiaj txhu
Tetramisole Hydrochloride tuaj yeem siv rau hauv kev yug tsiaj los tiv thaiv thiab kho kab mob kab mob. Tus kab mob Ascaris yog ib hom kab mob parasitic tsiaj uas tuaj yeem ua rau cov nqi tsim khoom ntau ntxiv hauv cov tsiaj txhu thiab cov teeb meem kev noj qab haus huv ntawm cov tsiaj. Tetramisole Hydrochloride tuaj yeem tswj cov kab mob kab mob sib kis thiab txhim kho cov tsiaj txhu ntau lawm.
Nqaij qaib
Tetramisole Hydrochloride tuaj yeem siv los tiv thaiv thiab kho cov kab mob nematode me me hauv cov nqaij qaib. Me me nematode kab mob yog ib qho kab mob parasitic nyob rau hauv cov nqaij qaib, uas tuaj yeem ua rau txo qis kev ua tau zoo thiab txo tus nqi noj mov. Tetramisole Hydrochloride tuaj yeem tswj tau cov kab mob nematode me me thiab txhim kho cov nqaij qaib ntau lawm.
Ib tug kws tshawb fawb npe hu ua Wright los ntawm ITRI (British Industrial Research Institute) tau tshawb pom qee cov tshuaj sulfuryl tshiab thaum tshawb nrhiav cov tshuaj synthesis tshiab. Ntawm lawv, 4-phenyl-2,3,5,6-tetrahydro-1H-pyrazole (THCP) tau ua tiav kev tiv thaiv kab mob zoo heev tiv thaiv feem ntau ntawm cov kab mob plab hnyuv loj, Helicobacter.
thaj chaw kho mob tab tom ua kev tshawb fawb thiab kev sim ntau yam ntawm THCP, uas xav kom siv los kho tib neeg kab mob parasitic. Kev tshawb fawb tau pom tias THCP tsis muaj kev kho mob tseem ceeb rau tib neeg cov kab mob hauv plab hnyuv, tab sis nws cov cocaine txuam nrog tau raug pov thawj los ua cov tshuaj tiv thaiv kab mob hauv plab.
Cov kws tshawb fawb tau pib txhim kho cov qauv ntawm 4-phenyl-2,3,5,6-tetrahydro-1H-pyrazole hauv kev tshawb nrhiav cov tshuaj tua kab mob zoo dua. Tom qab lub sijhawm ntev ntawm kev tshawb fawb, cov kws tshawb fawb thaum kawg tau hloov THCP rau hauv THFA, uas muaj zog tiv thaiv kab mob. Nyob rau tib lub sijhawm, kev solubility ntawm Tetramisole Hydrochloride kuj tau ua kom zoo dua qub.
Tetramisole Hydrochloride yog thawj zaug ua lag luam ua tshuaj rau kev kho mob plab hnyuv ileitis. Tom qab ntawd, Tetramisole Hydrochloride tau dav siv los kho ntau yam kab mob xws li kab mob kab mob sib kis, kab mob canine parvovirus, kab mob hookworm, thiab qee yam kab mob cab.
Sij hawm dhau mus, Tetramisole Hydrochloride tau maj mam dhau los ua cov tshuaj siv dav rau kev kuaj mob thiab kho cov kab mob canine thiab qee yam kab mob tib neeg. Tetramisole Hydrochloride yog suav tias yog ib qho ntawm cov tshuaj xaiv zoo tshaj plaws rau kev kho cov kab mob cab.
Cov kev mob tshwm sim ntawm cov tshuaj no yog dab tsi?
1.Cov teebmeem tshwm sim
Gastrointestinal tshuaj
Cov neeg mob yuav hnov mob xeev siab tom qab noj tetraimidazole hydrochloride, uas yog vim muaj kev txhawb zog ntawm cov tshuaj ntawm lub plab hnyuv mucosa. Qee tus neeg mob yuav muaj ntuav tom qab noj tshuaj, uas tseem cuam tshuam nrog kev ua kom lub plab zom mov los ntawm cov tshuaj. Thaum ntuav hnyav, nws yuav ua rau lub cev qhuav dej, electrolyte tsis txaus, thiab lwm yam hauv cov neeg mob. Tetraimidazole hydrochloride tuaj yeem ua rau lub plab hnyuv peristalsis nrawm, ua rau raws plab. Kev mob raws plab tsis tsuas yog cuam tshuam rau lub neej zoo ntawm cov neeg mob, tab sis kuj tseem tuaj yeem ua rau muaj teeb meem xws li kev nqus cov khoom noj tsis zoo.
Neurological teb
Cov tshuaj yuav cuam tshuam rau lub hauv nruab nrab lub paj hlwb, ua rau cov tsos mob ntawm kiv taub hau hauv cov neeg mob. Thaum kiv taub hau hnyav, nws yuav cuam tshuam rau tus neeg mob lub neej txhua hnub thiab kev ua haujlwm. Qee tus neeg mob yuav mob taub hau tom qab noj tshuaj, uas tej zaum yuav cuam tshuam rau cov tshuaj neurotoxicity. Thaum mob taub hau hnyav, nws yuav cuam tshuam rau tus neeg mob pw tsaug zog thiab mus ob peb vas.
Kev ua xua
Qee tus neeg mob yuav ua xua rau qee yam ntawm tetraimidazole hydrochloride, ua rau cov pob liab liab. Cov pob liab liab feem ntau tshwm sim raws li cov tsos mob xws li liab, o, thiab khaus ntawm daim tawv nqaij. Urticaria yog ib qho kev tshwm sim ntawm kev tsis haum tshuaj, thiab cov neeg mob yuav muaj cov tsos mob ntawm lub cev los yog hauv zos xws li wheals thiab khaus tom qab noj tshuaj. Kev tsis haum tshuaj hnyav tuaj yeem ua rau cov neeg mob ua pa nyuaj thiab ua rau muaj kev poob siab anaphylactic. Yog li ntawd, ib zaug cov tsos mob xws li ua pa nyuaj, yuav tsum tau nrhiav kev kho mob tam sim ntawd.
Lwm yam teebmeem
Qee tus neeg mob yuav muaj cov tsos mob ua npaws tom qab noj tshuaj, uas yuav cuam tshuam nrog kev tiv thaiv kab mob ntawm cov tshuaj. Cov tshuaj yuav ua rau cov neeg mob ntsib cov tsos mob ntawm kev qaug zog, cuam tshuam rau lawv lub neej txhua hnub thiab kev ua haujlwm.
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2.Drug cuam tshuam thiab kev phiv
Kev sib cuam tshuam nrog lwm yam tshuaj
Tetraimidazole hydrochloride tuaj yeem cuam tshuam nrog lwm cov tshuaj, ua rau muaj kev nce lossis txo qis, thiab txawm tias muaj kev phiv tshuaj tshiab. Yog li ntawd, thaum noj tetraimidazole hydrochloride, cov neeg mob yuav tsum qhia lawv cov kws kho mob txog lwm yam tshuaj uas lawv tau noj kom lawv tuaj yeem kho lawv txoj kev kho mob.
Kev sib tham nrog cawv
Kev haus cawv thaum siv tetraimidazole hydrochloride tuaj yeem ua rau muaj kev pheej hmoo ntawm kev phiv tshuaj. Cawv nws tus kheej muaj cov nyhuv stimulating ntawm lub plab hnyuv mucosa, thiab kev tswj hwm nrog tetraimidazole hydrochloride tuaj yeem ua rau mob plab zom mov. Tsis tas li ntawd, cawv kuj tseem tuaj yeem cuam tshuam cov metabolism thiab tso tawm ntawm cov tshuaj, ua rau cov tshuaj tsub zuj zuj hauv lub cev thiab ua rau muaj kev pheej hmoo ntawm kev phiv.
3.Kev ceev faj thiab kev tiv thaiv
- Ua raws li tus kws kho mob cov lus qhia txog tshuaj: Cov neeg mob yuav tsum sab laj nrog kws kho mob ua ntej noj Tetraimidazole Hydrochloride kom nkag siab txog cov lus qhia, ntau npaum li cas, kev ceev faj, thiab lwm yam ntawm cov tshuaj. Nyob rau tib lub sijhawm, cov neeg mob yuav tsum ua raws li tus kws kho mob cov lus qhia rau kev siv tshuaj, tsis txhob hloov nws tus kheej ntawm kev noj tshuaj lossis kev txiav tshuaj ntxiv.
- Saib xyuas cov tshuaj tiv thaiv: Cov neeg mob yuav tsum tau saib xyuas lawv cov tshuaj tiv thaiv thaum siv tetraimidazole hydrochloride. Thaum muaj kev phiv loj lossis kev tsis haum tshuaj tshwm sim, cov tshuaj yuav tsum tau nres tam sim ntawd thiab nrhiav kev kho mob.
- Cov neeg tshwj xeeb yuav tsum tau ceev faj: Cov poj niam cev xeeb tub, cov poj niam cev xeeb tub, menyuam yaus, cov neeg laus thiab lwm cov neeg tshwj xeeb yuav tsum tau ceev faj tshwj xeeb thaum noj tetraimidazole hydrochloride. Cov pejxeem no yuav tsum noj tshuaj raws li tus kws kho mob qhia thiab saib xyuas cov kev mob tshwm sim ntawm cov tshuaj.
- Zam kev tswj hwm nrog lwm cov tshuaj: Cov neeg mob yuav tsum zam kev tswj hwm nrog lwm cov tshuaj thaum siv tetraimidazole hydrochloride los tiv thaiv kev sib cuam tshuam ntawm cov tshuaj. Yog tias koj xav noj lwm yam tshuaj, thov nrog kws kho mob thiab qhia koj tus kheej tias koj noj tetraimidazole hydrochloride.
- Tsis txhob haus cawv: Cov neeg mob yuav tsum tsis txhob haus cawv thaum siv tetraimidazole hydrochloride kom tsis txhob ua rau lub plab zom mov hnyav dua lossis ua rau muaj kev pheej hmoo ntawm lwm yam kev mob tshwm sim.
- Kev saib xyuas lub siab thiab lub raum ua haujlwm tsis tu ncua: Cov neeg mob uas tau noj tetraimidazole hydrochloride ntev ntev yuav tsum tau saib xyuas lawv lub siab thiab lub raum ua haujlwm kom sai li sai tau thiab kho cov tshuaj puas rau lub siab thiab lub raum.
Dab tsi yog cov kev muag khoom rau qhov sib xyaw no?
Hom kev muag khoom channel
Chaw tsim khoom ncaj qha muag
Qee lub tuam txhab tshuaj lossis tshuaj lom neeg uas muaj peev xwm tsim tau ncaj qha muag tetraimidazole hydrochloride hmoov kom kawg cov neeg siv khoom lossis cov neeg xa khoom. Cov tuam txhab no feem ntau muaj kev tsim khoom tiav, kev tshuaj xyuas zoo, thiab kev muag khoom kom ntseeg tau cov khoom zoo thiab lub sijhawm xa khoom.
Distributor Agent
Cov neeg muag khoom thiab cov neeg sawv cev ua lub luag haujlwm tseem ceeb hauv kev muag khoom, feem ntau koom tes nrog ntau lub tuam txhab los faib cov khoom mus rau kev lag luam dav. Los ntawm lub koom haum distributor, manufacturers tuaj yeem nthuav cov kev muag khoom thiab nce kev lag luam.
E- lag luam platform
Nrog rau kev txhim kho ntawm e- kev lag luam, ntau thiab ntau cov khoom siv tshuaj thiab tshuaj raug muag los ntawm e- lag luam platforms. Tetramisole Hcl Powder kuj tuaj yeem pom ntawm qee cov tshuaj tshwj xeeb lossis tshuaj e- lag luam platforms, uas feem ntau muab cov ncauj lus kom ntxaws txog cov khoom lag luam thiab cov kev yuav khoom yooj yim.
Kev lag luam thoob ntiaj teb
Rau kev lag luam thoob ntiaj teb, tetraimidazole hydrochloride feem ntau yog muag los ntawm kev lag luam thoob ntiaj teb. Cov neeg tsim khoom lossis cov neeg xa khoom yuav koom tes nrog cov neeg xa khoom txawv teb chaws lossis cov neeg xa khoom xa tawm lawv cov khoom mus rau kev lag luam txawv teb chaws.
FAQ
1. Dab tsi yog daim ntawv thov tseem ceeb ntawm tiamulin hydrochloride?
Nws yog ib qho classic broad -spectrum deworming tshuaj, uas muaj txiaj ntsig zoo hauv kev tshem tawm cov kab mob sib kis thiab cov nematodes hauv ntau yam tsiaj (tshwj xeeb yog tsiaj txhu). Lus Cim: Cov tshuaj no tam sim no tsis haum rau tib neeg siv.
2. Vim li cas nws tsis tshua pom muaj nyob rau hauv kev kho tsiaj kho tsiaj niaj hnub no?
Vim nws txoj kev kho qhov muag nqaim, qhov koob tshuaj zoo nyob ze rau cov tshuaj lom neeg, uas tuaj yeem yooj yim ua rau muaj kev phiv (xws li neurotoxicity). Lub caij no, kev nyab xeeb dua tshiab deworming tshuaj (xws li albendazole thiab ivermectin) tau dav dav, maj mam hloov nws hauv cov ntawv thov tseem ceeb.
3. Nws muaj nuj nqis dab tsi tshwj xeeb hauv kev tshawb fawb txog kev tshawb fawb?
Nws daim ntawv levorotatory (levamisole) yog ib zaug txaus siab rau kev tshawb fawb txog tshuaj tiv thaiv kab mob raws li kev tiv thaiv kab mob, tab sis nws tsis tau siv dav. Daim ntawv thov tseem ceeb tshaj tam sim no yog tias nws daim ntawv dextrorotatory (dexamisole) feem ntau yog siv los ua chiral catalyst lossis daws tus neeg sawv cev hauv qee cov txheej txheem tshuaj lom neeg.
4. Dab tsi yog qhov kev pheej hmoo tseem ceeb yog tias kev noj tshuaj tsis raug lossis kev sib cuag tsis raug?
Nws yog tshuaj lom rau tib neeg. Cov tsos mob ntawm kev lom yuav muaj xws li xeev siab, mob taub hau, kiv taub hau, thiab nyob rau hauv cov xwm txheej hnyav, nws tuaj yeem ua rau lub hauv paus paj hlwb inhibition, ua pa tsis ua haujlwm thiab txawm tuag. Nws yuav tsum tsis txhob siv rau tib neeg nyob rau hauv txhua qhov xwm txheej. Kev tiv thaiv tus kheej yuav tsum tau ua thaum lub sijhawm ua haujlwm.
Cim npe nrov: tetramisole hcl hmoov cas 5086-74-8, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom