Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm 2-bromomalonaldehyde cas 2065-75-0 nyob Suav teb. Txais tos rau cov lag luam wholesale bulk zoo 2-bromomalonaldehyde cas 2065-75-0 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
2-Bromomalonaldehyde, tseem hu ua bromomalondialdehyde los yog bromomalealdehyde, yog ib qho tseem ceeb organic compound. Cov tsos mob feem ntau yog daj ntseg daj lossis tsis muaj xim rau cov kua daj daj, uas tuaj yeem yaj hauv dej thiab tseem soluble hauv cov kuab tshuaj organic xws li cawv, ethers, acetonitrile, thiab DMSO (me ntsis soluble). Thaum rhuab, nws yuav decompose thiab tej zaum yuav tsim cov pa roj hydrogen bromide. Cov tshuaj no yog lub ntsiab nruab nrab rau cov synthesis ntawm heterocyclic tebchaw xws li pyrimidine thiab imidazole, dav siv nyob rau hauv lub synthesis ntawm cov kua muaju thiab ib co raw khoom rau tshuaj synthesis. Nws kuj tseem siv tau los npaj cov tshuaj nruab nrab xws li Lometrexed. Yog li ntawd, nws yuav tsum tau muab cia kom nruj rau hauv qhov chaw txias thiab qhuav, tsis txhob sib cuag nrog oxidants, acids, thiab lwm yam khoom siv hluav taws xob los tiv thaiv kev phom sij lossis hluav taws kub.
Cov ntaub ntawv ntxiv ntawm chemical compound:
|
Tshuaj Formula |
C3H3BrO2 |
|
Exact Mass |
149.93 |
|
Molecular Luj |
150.96 |
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m/z |
149.93(100.0%),151.93(97.3%),150.93(3.2%),152.93(3.2%) |
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Elemental Analysis |
C, 23,87; H, 2.00 Nws; Ib., 52,93; Nws, 21.20 |
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Melting point |
132-136℃(lit.) |
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Boiling point |
134.8 ± 25.0℃(Tshaj tawm) |
|
Qhov ntom |
1.750 ± 0.06 g / cm3 (Kev kwv yees) |
|
Cia tej yam kev mob |
qis dua -20 degree |
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2-Bromomalonaldehyde, tseem hu ua bromomalondialdehyde, yog ib qho tseem ceeb organic compound nrog ntau yam kev siv hauv ntau yam. Cov hauv qab no yog cov lus piav qhia ntxaws txog nws lub hom phiaj:
1,4-Dihydroquinoline yog ib chav kawm ntawm biologically active compounds dav nyob rau hauv tej yam ntuj tso khoom thiab tshuaj . 2-bromomalondialdehyde tuaj yeem siv los tsim cov qauv ntawm 1,4-dihydroquinoline. Nws pawg C-3 chiral sulfoxide tuaj yeem ua tus qauv NADH cyclic, koom nrog kev txo qis asymmetric ntawm methyl benzoate los tsim methyl phenylethanoate. Cov txheej txheem tshuaj tiv thaiv no tsis tsuas yog muab txoj hauv kev tshiab rau kev sib txuas ntawm 1,4-dihydroquinoline, tab sis kuj muaj cov tswv yim tshiab rau kev txhim kho cov tshuaj cuam tshuam.
Acetaldehyde yog ib qho tseem ceeb tshuaj raw khoom siv dav hauv teb xws li dyes, fragrances, thiab pharmaceuticals . 2-bromomalondialdehyde tuaj yeem cuam tshuam nrog hloov guanine los ua glyoxal derived adducts. Cov adducts no tseem ceeb heev hauv cov tshuaj synthesis thiab kev tshawb fawb txog kev lom neeg. Acetaldehyde derived adducts tuaj yeem ua haujlwm tseem ceeb rau kev sib txuas ntawm cov tshuaj tshiab. Los ntawm kev kawm nws cov qauv thiab cov khoom, peb tuaj yeem nkag siab tob txog cov txheej txheem thiab cov cai ntawm cov tshuaj muaj feem cuam tshuam, muab lub hauv paus theoretical rau kev txhim kho cov tshuaj tshiab.
Lub caij no, cov adducts kuj tseem tuaj yeem muaj cov tshuaj pharmacological ncaj qha, muab cov neeg sib tw tshiab rau kev tsim tshuaj tshiab. Ntxiv rau cov lus saum toj no - hais txog kev siv, 2-bromomalondialdehyde kuj tuaj yeem koom nrog cov txheej txheem synthesis ntawm lwm cov tshuaj. Piv txwv li, nws tuaj yeem siv los ua ib qho ntawm cov khoom siv raw rau synthesizing qee yam tshuaj tiv thaiv qog.
Cov ntaub ntawv raw ntawm 2-bromomalondialdehyde muaj dav thiab tuaj yeem npaj tau los ntawm ntau txoj hauv kev. Qhov no ua rau nws muaj peev xwm zoo rau kev thov hauv thaj chaw kws tshuaj intermediates. Cov tshuaj tiv thaiv kab mob cuam tshuam nrog 2-bromomalondialdehyde yog qhov me me thiab tsis tas yuav muaj huab cua txias xws li kub thiab kub siab. Qhov no muaj txiaj ntsig zoo rau kev txo cov nqi tsim khoom thiab txhim kho kev tsim khoom. Los ntawm kev sib cais tsim nyog thiab kev ua kom huv huv, siab-purity 2-bromomalondialdehyde thiab nws cov derivatives tuaj yeem tau txais. Qhov no yuav pab ua kom cov tshuaj zoo thiab kev nyab xeeb ntawm cov tshuaj . 2-bromomalondialdehyde thiab nws cov derivatives muaj ntau hom tshuaj ua haujlwm thiab tuaj yeem siv los kho ntau yam kab mob. Qhov no muab ntau txoj kev xaiv thiab muaj peev xwm rau kev tsim tshuaj tshiab.
Environmentally friendly daim ntaub ntawv
Nrog rau kev paub txog kev tiv thaiv ib puag ncig, kev siv cov khoom zoo ib puag ncig tau txais kev saib xyuas ntau thiab ntau dua los ntawm tib neeg . 2-bromomalondialdehyde, raws li cov organic compound, muaj peev xwm muaj txiaj ntsig hauv qee qhov kev siv ib puag ncig vim nws cov yam ntxwv. Piv txwv li, 2-bromomalondialdehyde tuaj yeem siv los ua ib qho ntawm cov khoom siv hluavtaws rau cov ntaub ntawv biodegradable. Los ntawm copolymerizing nrog lwm cov biodegradable monomers, cov ntaub ntawv sib xyaw nrog biodegradability zoo heev thiab cov khoom siv tshuab tuaj yeem npaj tau.
Cov ntaub ntawv sib xyaw no muaj cov ntawv thov dav dav hauv cov khoom ntim, cov yeeb yaj kiab ua liaj ua teb, thiab lwm yam, uas tuaj yeem pab txo cov pa phem thiab tiv thaiv ib puag ncig. Tsis tas li ntawd, 2-bromomalondialdehyde kuj tuaj yeem siv los kho cov khoom tsis zoo hauv cov dej khib nyiab. Los ntawm kev qhia 2-bromomalondialdehyde, nws tuaj yeem hnov mob nrog cov khoom tsis zoo hauv cov dej khib nyiab thiab hloov mus rau hauv cov khoom tsis muaj teeb meem lossis tsis muaj tshuaj lom. Txoj kev no tsis tsuas yog pab ntxuav cov dej khib nyiab thiab tiv thaiv ib puag ncig, tab sis kuj tseem ua rau kev siv cov khoom pov tseg.
2-Bromomalonaldehyde(CAS naj npawb 2065-75-0) yog ib qho organic compound nrog cov mis molecular C ∝ H ∝ BrO ₂, nrog ib qho hnyav molecular ntawm 150.96 g / mol, feem ntau tam sim no nyob rau hauv daim ntawv ntawm lub teeb daj khoom. Cov qauv molecular muaj ob lub electrophilic aldehyde carbons thiab bromine atom uas yooj yim hloov los ntawm nucleophiles. Cov qauv tshwj xeeb no ua rau nws muaj zog "synthetic molecule" thiab tau qhia dav siv cov nqi hauv ntau yam xws li tshuaj, ntaub ntawv tshawb fawb, thiab kev tshawb fawb biochemistry.
Hauv kev tshawb fawb cov ntaub ntawv: txhawb kev tsim cov khoom siv tshiab
Synthesis ntawm Liquid Crystal Materials
Nws yog ib qho tseem ceeb raw khoom rau synthesizing tej yam tshwj xeeb kua siv lead ua molecules. Cov ntaub ntawv siv lead ua kua siv tau dav siv hauv cov khoom siv thev naus laus zis xws li LCD thiab OLED, thiab lawv qhov kev ua tau zoo cuam tshuam ncaj qha rau cov cim tseem ceeb xws li pom meej, teb ceev, thiab lub zog noj ntawm cov khoom siv. Nrog rau kev txhim kho txuas ntxiv ntawm cov cuab yeej siv thev naus laus zis thiab kev xav tau ntau ntxiv rau siab - cov ntaub ntawv ua tau zoo, txawm hais tias daim ntawv thov nyob rau hauv kev sib xyaw ntawm cov khoom siv ua kua siv lead ua tsis yog qhov dav li hauv chaw tshuaj, nws tseem yog qhov chaw ruaj khov ntawm kev thov.
Kev loj hlob ntawm cov ntaub ntawv organic optoelectronic
Cov synthesized heterocyclic compounds tau dhau los ua cov neeg sib tw zoo tshaj plaws rau kev tsim cov khoom siv xws li cov teeb pom kev organic-emitting diodes (OLEDs), organic solar cells (OPVs), thiab organic field-effect transistors (OFETs) vim lawv txoj kev sib txuas zoo heev thiab kev ua haujlwm photoelectrochemical. Cov ntawv thov tshwj xeeb suav nrog:
OLED cov ntaub ntawv: Heterocyclic tebchaw muab tau los ntawm 2-bromomalondialdehyde tuaj yeem siv los ua cov ntaub ntawv txheej txheej luminescent kom ua tiav cov xim sib txawv ntawm luminescence los ntawm kev kho lawv cov qauv molecular, yog li txhim kho cov luminescence efficiency thiab ruaj khov ntawm OLEDs.
Cov khoom siv OPV: Raws li tus neeg pub khoom lossis cov khoom lees paub, nws cov khoom sib xyaw heterocyclic tuaj yeem ua kom zoo dua qhov kev nqus ntawm lub teeb thiab them nqi hloov pauv kev ua haujlwm, thiab txhim kho cov kev hloov pauv photoelectric ntawm OPV.
OFET cov ntaub ntawv: Los ntawm kev siv cov khoom semiconductor ntawm heterocyclic compounds tau los ntawm 2-bromomalondialdehyde, kev ua haujlwm siab OFETs tuaj yeem npaj siv rau hauv thaj chaw xws li cov khoom siv hluav taws xob hloov pauv thiab cov ntse sensors.
Nrog rau txoj kev loj hlob sai ntawm cov organic electronics kev lag luam, qhov kev thov rau cov txheej txheem hauv tsev yuav tsum pom kev loj hlob tshiab.
Kev Tshawb Fawb Txog Kev Tshawb Fawb Biochemistry: Qhia txog Tshuaj Mechanisms ntawm Cov Txheej Txheem Ua Neej
Kev tshawb fawb txog DNA puas thiab kho cov txheej txheem
Nws tuaj yeem siv los ua tshuaj ntsuam xyuas los tsim cov khoom siv los ntawm kev ua haujlwm nrog cov nucleic acid hauv paus xws li guanine, pab cov kws tshawb fawb tshawb nrhiav cov tshuaj toxicity ntawm cov tshuaj tshwj xeeb. Piv txwv li, thaum kawm txog genetic toxicity ntawm tej yam ib puag ncig tej pa phem los yog tshuaj metabolites, 2-bromomalondialdehyde tuaj yeem simulate cov txheej txheem tshuaj tiv thaiv ntawm cov tshuaj no thiab DNA, qhia lawv cov carcinogenic lossis mutagenic mechanisms.
2. Kev tshawb fawb txog Enzyme Activity thiab Inhibition Mechanism
Nws pab pawg aldehyde tuaj yeem khi nrog cov active chaw seem ntawm cov enzyme (xws li ε - amino pawg ntawm lysine) los tsim cov adducts ruaj khov, yog li inhibiting cov haujlwm ntawm cov enzymes. Cov yam ntxwv no ua rau 2-bromomalondialdehyde yog ib qho cuab yeej zoo rau kev kawm txog kev sib raug zoo ntawm cov qauv enzyme thiab kev ua haujlwm. Piv txwv li, los ntawm reacting 2-bromomalondialdehyde nrog cov enzymes tshwj xeeb, qhov chaw ua haujlwm ntawm cov enzyme tuaj yeem txiav txim siab, ntxiv nthuav tawm cov txheej txheem catalytic ntawm enzyme.
Lwm cov teb: nthuav daim ntawv thov ciam teb
Nws cov reactivity siab thiab multifunctionality ua rau nws yog ib tug zoo tagnrho qauv molecule rau tshuaj synthesis methodology tshawb fawb. Los ntawm kev kawm cov tshuaj tiv thaiv ntawm 2-bromomalondialdehyde nrog cov reagents sib txawv, hom tshiab ntawm cov tshuaj tiv thaiv organic tuaj yeem tsim tau, cov tshuaj tiv thaiv tuaj yeem ua kom zoo dua qub, thiab cov tshuaj tiv thaiv yields thiab kev xaiv tuaj yeem txhim kho. Piv txwv li, los ntawm kev siv cov reactivity ntawm aldehyde pawg thiab bromine atoms nyob rau hauv 2-bromomalondialdehyde, multi-kauj ruam cascade cov tshuaj tiv thaiv yuav tsum tau tsim kom ua tau zoo synthesis ntawm complex molecules.
Catalyst tsim thiab tshuaj ntsuam
Raws li tus qauv molecule rau catalyst tsim, catalysts tshiab tuaj yeem tsim los ntawm simulating lawv cov txheej txheem tshuaj tiv thaiv. Piv txwv li, chiral catalysts tuaj yeem tsim los ua kom tiav asymmetric catalytic synthesis los ntawm cov tshuaj tiv thaiv condensation ntawm 2-bromomalondialdehyde nrog nucleophilic reagents. Tsis tas li ntawd, 2-bromomalondialdehyde kuj tuaj yeem siv los tshuaj xyuas cov tsev qiv ntawv catalyst thiab tshawb nrhiav cov catalysts nrog kev ua haujlwm siab thiab kev xaiv rau cov tshuaj tiv thaiv tshwj xeeb.
FAQ
Yog2-Bromomalonaldehydeteeb meem?
Malondialdehyde (MDA) yog tus thawj coj thiab feem ntau kawm cov khoom ntawm polyunsaturated fatty acid peroxidation. Qhov no aldehyde yog ibcov tshuaj lom molecule heevthiab yuav tsum tau suav tias yog ntau tshaj li qhov cim ntawm lipid peroxidation.
Cim npe nrov: 2-Bromomalonaldehyde CAS 2065-75-0, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom