Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab lwm tus neeg ntawm 3-phenoxyBenylentry CAS 13826-35-2 hauv Suav teb. Txais tos rau kev lag luam wholesale ntau yam zoo 3-phenoxybenzyl cawv CAS 13826-35-2 Kev muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
3-PhenoxyBenylenyyl Haus cawvyog cov organic sib xyaw nrog cov tshuaj noj cov tshuaj c13h12o2, CAS 13826-}}}}}}}}}}}}}}}, thiab yog tus dawb crystalline khoom. Nws muaj solubility tsawg hauv dej tab sis tuaj yeem yaj nyob rau hauv feem ntau cov kuab tshuaj organic. Nws tuaj yeem yaj dawb hauv cov kuab tshuaj xws li ethanol, methanol, thiab ethere tsis tas yuav hydrates. Tus tsis ruaj khov, tiv taus kev rhuav tshem lossis oxidation ntawm chav sov thiab siab. Txawm li cas los xij, muaj cov℃ntawm qhov tsis pom kev hauv lub teeb thiab huab cua. Nws muaj qee cov hluav taws redox thiab tuaj yeem txo rau cov coj benzaldehyde. Nws tseem tuaj yeem ua cov protein tyrosine Kinase inhibitor. Protein Tyrosine Kinase yog ib qho tseem ceeb molecule hauv qog cell proliferation thiab metastasis, thiab inhibiting nws cov haujlwm tuaj yeem txo cov kev tshwm sim thiab kev sib kis ntawm cov qog. Cov kev tshawb fawb yav dhau los tau pom tias los tiv thaiv mob cancer cancer tuaj yeem ua tiav los ntawm kev ua haujlwm ntawm cov protein tyrosine kinases. Nws yog cov organic compound uas tuaj yeem tau txais los ntawm cov qauv sib txawv synthesis. Nws muaj ntau yam siv thiab muaj cov ntawv thov hauv cov liaj teb xws li chemistry, tshuaj, tshuaj noj tshuaj, thiab lwm yam.
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Tshuaj Cov Qauv |
C13H12O2 |
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Muaj pes tsawg leej |
200 |
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Molecular hnyav |
200 |
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m/z |
200 (100.0%), 201 (14.1%) |
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Kev Ntsuam Xyuas |
C, 77.98; H, 6.04; O, 15.98 |
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3-PhenoxyBenylenyyl Haus cawv(CAS naj npawb: 13826-35-2, molecular tus qauv: C ₁α h ₁₂ ₁₂) yog cov organic sib xyaw ua ke nrog lub nplhaib benzene thiab benzyl cawv txiv neej. Nws cov tshuaj tshwj xeeb ua rau nws ua cov tshuaj tua kab, tshuaj, ntshav, cov ntaub ntawv kev tshawb fawb, thiab kev lag luam hluav taws xob, thiab kev lag luam hluav taws xob, thiab kev lag luam hluav taws xob, thiab kev lag luam hluav taws xob.
Nws yog cov tseem ceeb raw rau synthesizing cov tshuaj tua kab xws li chlorprifs, pyrethroids, thiab pyrethroids, thiab muaj lub hauv paus chaw nyob hauv lub ntiaj teb ua tshuaj. Nws daim ntawv thov tshaj 80%, thiab txhua xyoo kev thov tseem sawv nrog lub ntiaj teb xav tau kev tswj hwm kev ua liaj ua teb thiab kev noj qab haus huv.
1. Synthesis Tshuab thiab Cov Khoom Uas Raug
Synthesis ntawm chlorfenapyr: chlorfenapyr yog tsim los ntawm Esterification cov kev tshuaj tiv thaiv nrog chlorfenapyr acid. Cov khoom lag luam no muaj kev tiv thaiv plab thiab lub plab ua rau cov yoov tshaj cum xws li cov yoov tshaj cum, yoov, thiab yog cov tsev kho mob, tsev kho mob, thiab kev kho mob hauv tsev khomob.
Piv txwv li, lub tuam txhab chemical chemical siv 3-phenoxymethanol (polity ntau dua los yog sib npaug ntawm cov acidic catalyst, nrog cov txiaj ntsig ntawm 92%. Cov khoom tau ua kom zoo nkauj thiab tau ntsib tus qauv tshuaj tua kab.
Synthesis ntawm Pyrethroid: Rov qab nrog pyrethroids acid los tsim cov txiaj ntsig pyrethroid, cov khoom no muaj cov duab aphids thiab txiv hmab txiv ntoo ntsuab liab kab laug sab. Kev ua lag luam hauv tsev ua haujlwm luv luv ntawm cov hluavtaws ntawm pyrethemes ntawm pyrethemes ntawm pyrethemes ntawm syn hours and thiab txo cov nqi los ntawm kev ua kom zoo tshaj plaws (qhov kub (ntsuas nruab nrab, siab 0.5 mpa).
2. Kev ua tau zoo thiab kev lag luam kev lag luam
Ua tau zoo thiab qis toxicity: pyrethroids muaj cov teebmeem tshwj xeeb ntawm cov kab ntawm cov kab ntawm cov kab, nrog lub nrawm nrawm nrawm (LT50<5 minutes) and easy degradation in the environment (half-life<7 days). They have low toxicity to mammals (LD50>2000mg / kg), uas yog nyob rau hauv kab nrog kev txhim kho txij nkawm ntawm ntsuab tshuaj tua kab.
Kev lag luam loj: Lub chaw ua lag luam thoob ntiaj teb yuav tsum mus txog XX Billion US Dollars ntawm 6.2%, nrog rau kev xav tau kev vam meej txhua xyoo ntawm kev thov rau txhua xyoo} Phenoxy- benzylalcoho. Raws li cov ntaub ntawv los ntawm qee yam tshuaj siv hluav taws xob, tus nqi hauv tsev ntawm m- penoxy {}, xav txog kev ua haujlwm zoo rau 2023, xav txog qhov teeb meem zoo thiab xav tau kev lag luam hauv khw.
3. Ntau Lawm Txheej Txheem Txhim Kho
Txheej txheem tsoos: Siv m - PhenoxyBenhaldehde yog nqa tawm ntawm lub xub ntiag, uas yog sib cais thiab sodilled kom tau cov khoom.
The yield of this process is about 75%, but it produces a large amount of saline wastewater (COD>10000mg / l), thiab tus nqi kho mob yog siab.
Cov txheej txheem ntsuab: Siv catalalytic hydrogenation txo cov thev naus laus zis, thiab hydrogenation txo yog siv los ua cov khoom siv roj carbon monoxide thiab hydrogende (pd / c) thiab tsis muaj dej tawm. Ib qho chaw lag luam tau txo nws txoj kev noj haus rau 0.95 tons mus rau 0.95 tons / tuj ntawm cov khoom lag luam los ntawm hydrogen, ua rau 12% txo nqi.
Kws ua teb cov chaw: multifununctional intermediates rau cov tshuaj synthesis
Ua si lub luag haujlwm tseem ceeb hauv cov tshuaj sapticaltis, nws cov derivates ua tau dav hauv kev ua yeeb yam hauv cov tshuaj, thiab kev txhawb nqa cov tshuaj tshiab.
1. Cov tshuaj tiv thaiv hluavtaws
Cefotaxin tshuaj tua kab mob: lawv cov derivatives (xws li sab saw hlau ua ntej ua ntej ntawm cov cugazolin xws li Cefazolin thiab cefradradine. Piv txwv li, lub tuam txhab tuam tsev luam yeeb ua rau muaj lub cev ua ntu zus los ntawm reacting 3-kev haus dej phenoxybenzylNrog thioacetic acid, uas yog ces oxidized thiab hydrolyzed kom tau txais cov khoom lag luam. Tag nrho cov txiaj ntsig tau txog 65%, thiab kev coj dawb huv ntau dua los yog sib npaug rau 99.5%, uas tau ntsib cov qauv tshuaj papacopopoeia.
Penicillins: lawv cov derivatives tau siv nyob rau hauv synthesis ntawm potassium v potassium, uas ua kom muaj zog (bioavailability nce ntxiv los ntawm 2 zaug hauv PH 2.0 cov xwm txheej) los ntawm kev qhia cov pab pawg phenoxyl.
2. Anti cov siv qog siv qog
Paclitael analogues: Paclitaxel analogues nrog anti {{{0} Cov qog ua si tuaj yeem suav cov lus qhia fluorine atoms lossis nitrogen heterocycles). Ib pab neeg tshawb fawb nws nrog Propylene Oxide los tsim cov khoom sib xyaw ua ke nrog 85%
Lub hom phiaj tshuaj yeeb tshuaj: nws pawg benzyl cawv tau khi nrog polyethylal glycolic {{1} -}} li doxorubicin), Txhim kho cov tshuaj tiv thaiv kev siv tshuaj (nce cov qog nqaij tso tawm los ntawm 4 zaug) thiab bioavailability (nce auc
3. Central Ntshav Yeeb Tshuaj
Cov tshuaj tiv thaiv kev hloov siab: nws cov derivatives (xws li 3-phenoxybenzy, txhim kho kev tswj hwm los ntawm cov serotonin (5-ht) thiab norepinephrine (ne).
Ib txoj kev kawm ua ntej pom tias 3-phenoxybenzyakine derivatives muaj lub sijhawm antide lub sijhawm zoo dua (50% txo cov tshuaj tiv thaiv kab mob immobility (kev tswj hwm zoo) hauv kev yuam kev ua luam dej hauv nas.
Analgesics: cov pab pawg phenoxyl hauv lawv cov qauv tuaj yeem txhim kho cov tshuaj uas muaj peev xwm los ntawm cov tshuaj mus rau qhov tshiab opioid recepor, thiab yog siv los synthesize tshiab analgesics. Piv txwv li, qhov kev ua tau zoo ntawm kev ua kom zoo (ed} mg / kg} benzylaloho morphine}
Hauv thaj teb ntawm dyes thiab cov ntxhiab: hluavtaws raw cov ntaub ntawv rau high - Cov ntaub ntawv ua tau zoo
M - Phenoxy- benzylalcoho yog tsuas yog siv los ua ke siab thiab fluorescent brainters nyob rau hauv qhov kev lag luam zas xim. Nyob rau tib lub sijhawm, nws yog qhov tseem ceeb hauv synmediate rau cov synthesis ntawm essence nyob rau hauv lub essence nyob rau hauv lub otence teb los txhim kho cov xim ceev thiab aroma durability ntawm cov khoom.
1. Dispersed Dyes
Synthesis me nyuam yaus: m - Phenoxy} benzylalcoho}} nitroxy pawg (xws li penoxy pawg (xws li cov lus sib txuas lus phenxyzene) Disperse liab thiab tawg xiav.
Piv txwv li, cov tuam txhab zas coluted m - benzyloroho nrog 4 qib tawg ntau dua li ib txwm ua tsis zoo.
Kev ua tau zoo: Cov lus qhia ntawm phenoxyl pawg tuaj yeem txhim kho qhov tsis txaus ntseeg ntawm kev tuag (dispersion index di<0.5) and heat resistance (no decomposition at 300 ℃), making dyed fabrics have excellent color fastness (sun fastness ≥ level 6) and brightness (L * value in Lab color space increased by 10%).
2. Fluorescent whitening tus neeg sawv cev
Application example: Reacting with stilbene derivatives (such as 4,4 '- bis (2-sulfonated styrene) biphenyl) to synthesize fluorescent whitening agent OB-1 for whitening treatment of plastics, paper, and textiles. For example, a certain company applied OB-1 to polypropylene (PP) film, which can increase the whiteness (CIE whiteness value>90) of the film by 30%, and the light resistance (whiteness retention rate>85% tom qab 1000 teev ntawm Xenon teeb Irradiation) yog qhov zoo dua li cov neeg sawv cev dawb.
Market trend: With the strict environmental regulations, the demand for low toxicity and high-efficiency fluorescent whitening agents is increasing. The acute toxicity (LC50>100mg / l) ntawm tus neeg sawv cev tshiab ua kom zoo nkauj3-PhenoxyBenylenyyl Haus cawvRaws li cov khoom siv raw) rau dej yug tsiaj yog qis dua li cov khoom lag luam ib txwm muaj (LC {} mg / l), uas ua tau raws li qhov yuav tsum tau ua tiav.
3. Spice synthesis
Floral qab: naj hoom intermediates nrog 3-phenoxybenzaldehdehde), thiab siv los npaj sawv, Jasmine thiab lwm yam tsw.
Piv txwv li, qee cov neeg tuam txhab spice oxidizes rau cov tshuaj uas los tsim 3-phenoxybenchalhyde, uas yog ces condensanol kom tau txais cov tshuaj tsw qab nrog lub rose aroma. Nws cov qauv ua yeeb yam (aroma tus nqi fv=500}) yog ob zaug uas sawv ntawm cov roj tseem ceeb.
Natural spice replacement: Its structure is similar to that of natural spice components (such as phenylethanol in Damascus roses), making it a low-cost alternative to natural spices. A certain cosmetics company uses m-phenoxy-benzylalcoho derivatives to replace some natural rose essential oil, reducing product costs by 40%, and the fragrance persistence (fragrance retention time>8 teev) yog piv rau cov khoom ntuj.
Siv nyob rau hauv cov ntaub ntawv kev kawm kom synthesize cov ntaub ntawv polymer, cov tiv thaiv cov hlau, thiab kev txhawb nqa hluav taws xob thev naus laus zis tshiab.
1. Cov ntaub ntawv Polymer
Polyurethane Elastomer: Raws li cov saw txuas ntxiv, pab pawg tiv thaiv hluav taws xob (kua qaub thiab cov pa roj polyurethane. Toluene Diisocyanate (TDI) los tsim cov polyurethaner Prepolymer muaj cov pab pawg polyurethane, uas yog tom qab ntawd Butanediol kom tau txais polyurethane elastomer rau kev khi. Nws lub zog tensile (ntau dua los yog sib luag rau 50mpa) thiab kua muag (loj dua los yog sib npaug rau 100knon yog zoo dua rau cov khoom lag luam ib txwm muaj.
Epoxy Resin Tus Neeg Saib Xyuas Tus Neeg Sawv Cev: Siv ua ke nrog Ethylene capine), nws tuaj yeem hloov kho lub cev ua kom nrawm dua 30 feeb), txo cov kev ntxhov siab sab hauv (shrinkage<0.5%), and improve the mechanical properties of the epoxy resin (impact strength is increased by 30%).
2. Kev tiv thaiv hlau
Corrosion Inhibitor: Nws cov sulfur atoms tuaj yeem tsim zaj duab xis adsorption zaj duab xis nrog cov hlau corrosive (xws li h ₂ s, cl ⁻).
Piv txwv li, pab pawg tshawb fawb ntxiv3-PhenoxyBenylenyyl Haus cawvTxhawm rau sim ua dej hiav txwv (3.5% nacl), uas txo cov roj carbon hlau (0.01mm / y) los ntawm daim duab tsis sib xws (0.1mm / y) los ntawm daim nyias nyias (0.1mm / y) los ntawm daim nyias nyias (0.1mm / y)
Lubricating Roj Siab Tshaj Plaws Ntxiv: nyob rau hauv cov kev kub siab thiab cov mob siab rau cov iav sib kis), xws li}<0.05), improving the extreme pressure and anti-wear performance of gear oil (four ball machine test wear spot diameter<0.4mm).
M - Phenoxy - benzylalcoho yog cov organylalcoho yog cov organic compound uas tuaj yeem ua ke los ntawm kev kuaj me nyuam sib txawv. Ob txoj kev synthesis feem ntau yuav raug qhia thiab coj cov tshuaj sib txig sib luag.
Txoj kev 1: Grignard reassent txoj kev
Cov kauj ruam cov ntsiab lus:
Kauj Ruam 1: Rov ua pob benzaldehyde thiab magnesium bromide nyob rau hauv ib puag ncig tsis muaj dab tsi los tsim grainent benzaldehyde raws Magnesium bromide (phch2mgbr).
C7H6O + mgbr2→2MGB + h2O
Kauj Ruam 2: Rov qab cuam tshuam Benzylmagnesium Bromide nrog Phenol los ua cov khoom lag luam.
PHCH2Mgbr + C6H6O → C13H12O2+ Mgbroh
Kauj ruam 3: Hydrolyze grignard reagent thiab ua kev kho mob nruab nrab.
Mgbroh + hc → mgcl2+H2O
Khoom ntxiv thiab ua kom huv:
Kom zoo, ntxuav, thiab mloog cov tshuaj tiv thaiv cov tshuaj tiv thaiv kom tau txais 3 phenoxyBenylenylenylenyyl cawv.
Txoj Kev 2: Benzyl Cawv Oxidation Txuj Ci
Cov kauj ruam cov ntsiab lus:
Kauj Ruam 1: Rov qab ua rau cov dej cawv benzyl thiab sodium hydroxide nyob rau hauv ib qho tsim nyog benvent los ua kom muaj cov dej cawv benzyl sodium.
C7H8O + naoh → c7H7Ona + h2O
Kauj Ruam 2: Nyob rau hauv Alkaline tej yam kev mob, Benzyl Cawv sodium ntsev thiab cov hydrogen peroxide los ua cov benzyl cawv.
C7H7Ona + h2O2 → C7H7Ooh + naoh
Kauj ruam 3: Benzyl Cawv peroxide reacts nrog phenol los tsim cov khoom lag luam.
C7H7Ooh + c6H6O → C13H12O2+H2O
Kauj Ruam 4: Kev kho mob nruab nrab.
Naoh + hc → nacl + h2O
3. Khoom extraction thiab Purification:
Kom raug extract, ntxuav, thiab mloog cov tshuaj tiv thaiv kom tau txais3-PhenoxyBenylenyyl Haus cawv.
Thov nco ntsoov tias cov lus saum toj no yog ob txoj kev kuaj hluav taws xob synchantis thiab coj cov tshuaj sib txig sib luag. Cov hau kev no yog siv xwb xwb, thiab cov kev sim tshwj xeeb thiab cov kauj ruam yuav sib txawv raws li cov khoom siv hauv kev kuaj thiab ua haujlwm. Thaum coj mus kuaj cov khoom siv hluav taws xob, thov ua raws cov txheej txheem kev ua haujlwm nyab xeeb thiab kev kuaj cov lus taw qhia.
Cim npe nrov: 3-PhenoxyBenylenylen Cawv Cas 13826-35-2, Tus neeg muab khoom, chaw tsim khoom, chaw tsim khoom, yuav khoom, nqe, loj, rau muag