Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm cremophor el cas 61791-12-6 nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo cremophor el cas 61791-12-6 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Cremophor EL, CAS 61791-12-6, Molecular formula NULL. Yellow to light yellow viscous liquid or paste, qee cov qauv xws li EL-10 tuaj yeem pom pob tshab ntawm qhov kub thiab txias. Yooj yim rau yaj hauv dej, fatty acids, ntxhia roj, thiab ntau yam organic solvents, nrog zoo solubility nyob rau hauv dej txias dua nyob rau hauv dej kub. Resistant rau cov dej tawv, kua qaub, alkali, thiab inorganic ntsev, tab sis tej zaum yuav undergo hydrolysis thaum raug alkali muaj zog. Qhov tseem ceeb txo qhov kub thiab txias ntawm cov qauv zoo tib yam li ntawm 50-70 degree, HEL series tuaj yeem tiv taus qhov kub siab dua vim kev kho hydrogenation (xws li qis coking ntawm qhov kub siab hauv HEL-20). Qhov nro ntawm cov dej ua rau cov tshuaj pleev kom ruaj khov thiab cov kab mob dispersion.
Nws yog cov khoom siv polyethoxylated tsim los ntawm kev sib ntxiv ntawm cov roj castor thiab epoxyethane, uas muaj ob qho tib si hydrophilic polyoxyethylene chains thiab lipophilic castor roj pawg hauv nws cov qauv molecular. Raws li cov lej sib txawv ntawm cov ethylene oxide, cov khoom tuaj yeem muab faib ua ntau yam qauv xws li EL-10, EL-20, EL-40, EL-80, HEL-20, thiab lwm yam. Ntawm lawv, "EL" sawv cev rau cov roj castor roj polyoxyethylene ether, thiab "HEL" sawv cev rau hydrogenated castor roj polyoxyethylene resistant (kev kho cua sov thiab oxidation).
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Qhov ntom |
1.05 g / ml ntawm 20 ° C |
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Flash point |
257 degree |
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Kev cia khoom |
refreshator (+ 4C) |
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Daim ntawv |
Cov kua nplaum |
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Xim |
Ntshiab daj |
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Tus nqi PH |
5.0-7.0 (1g / 10 ml hauv H2O) |
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Kev ruaj ntseg |
Stable Incompatible nrog storng oxidizing tus neeg sawv cev. |
Castor roj polyoxyethylene ether tseem hu ua emulsifier EL-40, thiab cov khoom lag luam txawv teb chaws yog Emulphor EL-620. Nws belongs rau non-ionic surfactant. Pleev daj pob tshab viscous kua. Nws yog yooj yim soluble nyob rau hauv dej, roj, fatty acid thiab ntau yam organic solvents. Nws yog soluble ntau dua hauv dej txias dua hauv dej kub, thiab muaj kev ua haujlwm zoo emulsification rau cov roj ntxhia . 1% aqueous solution pH=6-8. HLB value 13. Huab point of 1% aqueous solution>=85℃. Nws yog resistant rau acid, dej nyuaj thiab inorganic ntsev. Nws kuj tseem tiv taus alkali ntawm qhov kub thiab txias, tab sis muaj zog alkali tuaj yeem ua rau nws hydrolyze. Castor roj polyoxyethylene ether tuaj yeem npaj tau los ntawm cov roj castor nrog ethylene oxide nyob rau hauv catalysis ntawm sodium hydroxide (los yog potassium hydroxide). Haum rau emulsification ntawm cov roj zaub, cov roj ntxhia, roj, siv quav ciab, thiab lwm yam. Nws kuj tseem siv tau los ua cov khoom siv ntawm cov khoom siv roj hmab rau cov khoom siv hluavtaws xws li polyacrylonitrile, tshuaj tua kab emulsifier, wool conditioner thiab wool oil.
Lub invention muaj feem xyuam rau ib txoj kev siv hluavtawsCremophor EL, teej tug mus rau kev teb ntawm organic compound synthesis, uas yog npaj los ntawm polymerizing castor roj thiab ethylene oxide nyob rau hauv lub xub ntiag ntawm ib tug catalyst; Qhov hnyav piv ntawm cov roj castor thiab ethylene oxide yog 1: 0.145 ~ 2.98; Cov catalyst yog ib qho los yog ntau qhov sib xyaw ntawm cov khoom siv sodium methoxide, sodium methoxide methanol tov, KOH, NaOH, thiab lwm yam, thiab cov nyiaj ntxiv yog 0.05 ~ 0.2% ntawm qhov hnyav feem pua ntawm cov roj castor roj polyoxyethylene ether. Cov txheej txheem tsis thiab tej yam kev mob, xws li raw khoom piv, tus nqi catalyst, polymerization kub thiab lub sij hawm, tau txiav txim siab. Cov tshuaj tiv thaiv mob me me thiab cov kev xav tau ntawm cov cuab yeej siv tsawg. Thiab cov tawm los yog siab, tsis muaj impurities yog generated, thiab ib puag ncig yog tus phooj ywg. Lub castor roj polyoxyethylene ether npaj los ntawm txoj kev muaj qhov zoo ntawm lub teeb xim, pob tshab tsos, zoo levelness, muaj zog compatibility thiab ntau yam ntawm adjustable npliag molecular luj.
Polyethylene Castor Roj (PEO Castor Roj), raws li cov chav kawm tseem ceeb ntawm cov tsis yog -ionic surfactants, tau qhia dav daim ntawv thov nqi nyob rau hauv ntau lub teb xws li textiles, pharmaceuticals, tshuaj tua kab, tshuaj pleev ib ce, inks, thiab hlau ua vim nws tshwj xeeb tshuaj qauv thiab zoo heev zog.
Daim Ntawv Thov Kev Lag Luam Textile
Hauv kev lag luam textile, nws yog siv los ua cov khoom siv roj hluavtaws thiab cov khoom siv roj, nrog cov haujlwm tseem ceeb xws li tiv thaiv - zoo li qub, lubrication, softness thiab smoothness, thiab defoaming.
1. Tshuaj Fiber Oil Agent
Antistatic kev ua tau zoo: Cov tshuaj fibers muaj qhov cuam tshuam rau hluav taws xob zoo li qub thaum lub sij hawm ncab, cua sov, thiab lwm yam kev ua, ua rau fiber ntau adhesion thiab nce kev tawg.
Los ntawm adsorbing mus rau saum npoo ntawm fibers los tsim ib txheej conductive, hluav taws xob zoo li qub tau raug tshem tawm zoo. Piv txwv li, EL-40 tuaj yeem siv los ua cov roj wool hauv kev lag luam wool spinning, thiab thaum sib xyaw nrog lwm cov tshuaj tiv thaiv zoo li qub, nws tuaj yeem txhim kho cov nyhuv anti-static.
Lubrication thiab Softness: Cov qauv xws li EL-20 thiab EL-80 tuaj yeem txo qhov kev sib txhuam coefficient ntawm fibers, ua rau qhov loj me thiab du, thiab txo qhov tawg. Piv txwv li, EL-80 tuaj yeem siv los ua cov roj spinning rau cov hluavtaws fibers xws li acrylic, vinylon, thiab polypropylene, txhim kho glossiness thiab tes xav ntawm cov fibers.
Kev ruaj ntseg kub siab: HEL-20 muaj cov yam ntxwv qis coking vim kev kho hydrogenation, ua rau nws tsim nyog rau cov txheej txheem kub-kub spinning thiab txuas cov cuab yeej siv lub neej.
2. Weaving roj tus neeg sawv cev
Loj defoaming: hluavtaws loj yog ib qho yooj yim los tsim ua npuas ncauj thaum sib tov, uas cuam tshuam rau weaving efficiency. Raws li ib tug defoamer, nws yuav sai sai ua puas lub stability ntawm ua npuas ncauj. Piv txwv li, EL-10 yog siv dav hauv polyester, polyacrylonitrile thiab lwm yam tshuaj fiber ntau.
Npuag Softening: Los ntawm kev siv cov softeners xws li emulsified silicone roj, cov ntaub yog muab rau cov tawv nqaij tus phooj ywg kov, txhim kho tus nqi ntxiv ntawm cov khoom.
Pharmaceutical kev lag luam daim ntawv thov
Nyob rau hauv kev lag luam teb, nws yog tsuas yog siv los ua ib tug solubilizer thiab emulsifier los daws cov teeb meem solubility ntawm roj soluble tshuaj.
1. Tshuaj solubilization
Semisolid thiab kua formulations: Cov qauv xws li EL-40 tuaj yeem solubilize dej-insoluble tshuaj (xws li cov vitamins thiab cov tshuaj hormones) rau hauv aqueous media, tsim cov kev daws teeb meem ruaj khov. Piv txwv li, hauv cov tshuaj pleev thiab tshuaj pleev, HLB tus nqi (hydrophilic lipophilic tshuav nyiaj li cas) tuaj yeem tswj tau los ntawm kev kho tus lej ntawm ethylene oxide kom ua tiav cov txiaj ntsig zoo solubilization.
Nce transmembrane permeability: Los ntawm kev txhim kho kev sib cuam tshuam ntawm cov tshuaj molecules thiab cell membranes, nws txhawb kev nqus tshuaj.
2. Daim ntawv thov Emulsifier
Kev npaj emulsion: Hauv O / W (dej hauv cov roj) emulsions, qhov kev sib tshuam ntawm cov roj thiab dej tuaj yeem raug txo kom tsim cov tee me me. Piv txwv li, hauv kev txhaj tshuaj ntawm cov roj emulsion, nws cov emulsifying stability ncaj qha cuam tshuam rau kev nyab xeeb tshuaj.
Sterilization compatibility: resistant rau kub thiab siab sterilization, haum rau zus tau tej cov sterile npaj.
Kev siv tshuaj tua kab hauv kev lag luam
Raws li cov tshuaj tua kab emulsifier,Cremophor ELtuaj yeem txhim kho cov dispersibility, permeability, thiab stability ntawm cov tshuaj tua kab.
1. Kev ruaj ntseg ntawm cov tshuaj pleev ib ce
Emulsification ntawm organophosphorus tshuaj tua kab: Piv txwv li, EL-80 yuav siv tau rau emulsification ntawm dimethoate thiab lwm yam tshuaj tua kab los tsim ib tug ruaj khov lotion nrog particle loj tsawg dua 5 μ m, txo stratification thiab nag lossis daus.
Optimization ntawm suspension agent formula: Los ntawm compounding nrog dispersants, lub adhesion thiab tsis kam mus rainwater yaig ntawm tshuaj tua kab ntawm nplooj yog txhim kho.
2. Kev ua tau zoo nce thiab txo qis
Enhanced permeability: txo qhov nro ntawm cov tshuaj tua kab, txhawb kev sib kis thiab nkag mus rau cov tshuaj tua kab ntawm cov nroj tsuag. Piv txwv li, ntxiv EL-40 rau cov tshuaj tua kab tuaj yeem ua kom muaj txiaj ntsig zoo ntawm 15% -20%.
Cov txiaj ntsig ntawm ib puag ncig: txo cov tshuaj tua kab thiab txo cov pa phem rau ib puag ncig.
Daim ntawv thov hauv kev lag luam tshuaj pleev ib ce
Castor roj polyoxyethylene ether feem ntau yog siv los ua emulsifier, solubilizer, thiab tus neeg sawv cev ntub dej hauv cov tshuaj pleev ib ce los txhim kho cov khoom ruaj khov thiab cov neeg siv kev paub.
1. Kev tsim kho ntawm Emulsification System
O/W lotion: Nyob rau hauv cov tshuaj pleev ib ce thiab lub ntsej muag cream, EL-40 thiab lwm yam emulsifiable roj cov khoom xyaw tuaj yeem tsim kev zoo nkauj thiab ruaj khov. Piv txwv li, nyob rau hauv cov tshuaj pleev thaiv hnub, nws cov khoom emulsifying xyuas kom meej tias cov tshuaj pleev thaiv hnub yog sib npaug.
W / O lotion: Nws kuj tuaj yeem siv rau cov khoom siv dej noo los ntawm kev kho cov qauv sib piv.
2. Solubilization thiab ntub dej
Essence solubilization: solubilize roj soluble essence rau hauv dej theem los txhim kho cov tshuaj tsw qab durability.
Cov tawv nqaij affinity: txo cov mis irritation thiab txhim khu cov neeg siv kev nplij siab.
Daim ntawv thov hauv Ink and Coatings Industry
Feem ntau yog siv los ua dispersants thiab leveling agents hauv inks thiab coatings los txhim kho kev luam ntawv zoo thiab txheej txheej.
1. Ink dispersibility
Pigment dispersion: Nyob rau hauv tus cwj mem, EL-80 thiab lwm yam qauv tuaj yeem ntim cov xim xim kom tiv thaiv agglomeration thiab txhim khu xim saturation.
Liquidity optimization: Txo tus number case viscosity, txhim kho luam ntawv ceev thiab meej.
2. Txheej leveling zog
Kev tiv thaiv shrinkage: Txo qhov sib txawv ntawm qhov sib txawv ntawm cov txheej txheem kom tsis txhob muaj qhov tsis xws luag xws li shrinkage thiab txiv kab ntxwv tev.
Kev txhim kho dej tsis kam: Los ntawm kev siv cov khoom siv xws li emulsified wax, cov dej tsis zoo ntawm cov txheej txheej yog txhim kho.
Hlau ua thiab siv cov tshuaj ntxuav
Feem ntau yog siv los ua emulsifiers thiab cov neeg ua dej ntub dej hauv cov kua dej ua haujlwm hlau thiab cov tshuaj ntxuav kom txhim kho kev ua haujlwm thiab kev tu kom zoo.
1. Hlau ua kua
Txiav kua emulsification: Cov qauv xws li EL-40 tuaj yeem emulsify cov roj ntxhia rau hauv cov kua dej ruaj khov, muab cov cua txias, lubrication, thiab tiv thaiv xeb.
Kev tiv thaiv xeb kev ua tau zoo: Los ntawm emulsifying xeb inhibitors, kev pabcuam lub neej ntawm cov khoom hlau txuas ntxiv.
2. Tus neeg saib xyuas tus qauv qauv
Decontamination muaj peev xwm: txo qhov nro ntawm dej thiab txhim kho nws lub peev xwm los yaj cov roj thiab av.
Kev tsim ua npuas ncauj qis: haum rau siab - cov cuab yeej siv lub zog kom txo qis kev cuam tshuam ntawm npuas ntawm cov khoom siv.
Kev thov hauv lwm qhov chaw
1. Kev lag luam tawv
Fatliquor: EL-20 thiab lwm yam qauv muaj peev xwm emulsify roj thiab rog, muab tawv softness thiab glossiness.
Tanning aids: txhawb nqa kev nkag mus ntawm cov neeg ua haujlwm tanning thiab txhim kho tawv zoo.
2. Kev lag luam roj av
Crude roj demulsification: Raws li ib tug demulsifier, nws cais dej los ntawm cov roj crude los txhim kho kev rov qab efficiency.
Drilling kua additives: txhim kho rheological zog ntawm drilling kua thiab tiv thaiv wellbore vau.
Cremophor ELtau dhau los ua ib qho tseem ceeb surfactant nyob rau hauv ntau qhov kev lag luam vim nws cov khoom siv tshuaj zoo heev thiab kev siv dav dav. Nyob rau hauv lub neej yav tom ntej, nrog kev nce qib ntawm thev naus laus zis thiab kev txhim kho kev lag luam kev xav tau, nws daim ntawv thov muaj peev xwm nyob rau hauv siab -kev tsim khoom kawg, biomedicine, lub zog tshiab thiab lwm yam kev lag luam yuav raug tso tawm ntxiv. Nyob rau tib lub sijhawm, kev nce hauv kev tiv thaiv ib puag ncig yuav ua rau cov tuam txhab nce lawv cov kev tshawb fawb thiab kev tsim kho hauv cov khoom ntsuab, txhawb kev txhim kho lawv cov kev lag luam mus rau kev ua tau zoo dua thiab cov lus qhia ruaj khov.
FAQ
Cremophor EL yog dab tsi?
Cremophor EL (CrEL) yog lub tsheb tsim qauv siv rau ntau yam tsis zoo -cov tshuaj soluble dej, suav nrog cov tshuaj tiv thaiv kab mob paclitaxel (Taxol). Nyob rau hauv sib piv rau yav dhau los cov ntaub ntawv, CrEL tsis yog ib tug inert lub tsheb, tab sis exerts ib tug ntau yam ntawm cov tshuaj lom, ib co ntawm cov uas muaj feem xyuam rau cov tshuaj tseem ceeb.
Cov tshuaj twg muaj Kolliphor EL?
Miconazole, tiv thaiv -fungal.
Paclitaxel (Taxol), tiv thaiv - mob qog noj ntshav.
Aci-Jel (acetic acid / oxyquinoline / ricinoleic acid - qhov chaw mos)
Sandimmune (kev txhaj tshuaj cyclosporine, USP)
Nelfinavir mesylate, HIV protease inhibitor.
Cov teebmeem ntawm Cremophor EL yog dab tsi?
Kev ntxhov siab ntxhov siab rau Cremophor EL- muaj cov paclitaxel ntau yam los ntawm me me pruritus mus rau cov kab mob anaphylaxis thiab tuaj yeem ua rau muaj feem cuam tshuam txog kev kho mob hnyav, suav nrog kev ua pa nres, mob plawv, thiab tuag.
Puas yog Cremophor EL yog surfactant?
Nws daim ntawv tam sim no ua lag luam raws li kev txhaj tshuaj intravenous paclitaxel yog solubilized los ntawm kev siv Cremophor EL, uas yog ib tug nonionic surfactant thiab pab nyob rau hauv lub micellar solubilization.
Cim npe nrov: Cremophor el CAS 61791-12-6, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom