4-methylcatechol hmoov, molecular mis C7H8O2, CAS 452-86-8, Nyob rau hauv chav tsev kub thiab siab, nws yog ib tug dawb mus rau dawb crystalline hmoov nrog tej yam solubility nyob rau hauv dej. Nws yog phenolic derivative nrog acidity tseem ceeb, uas tuaj yeem npaj los ntawm ntuj 4-methylguaiacol los ntawm oxidation cov tshuaj tiv thaiv. Hauv cov organic synthesis, cov tshuaj no tuaj yeem siv rau kev npaj ntawm catechol derivatives los ntawm acidity thiab nucleophilicity ntawm phenolic hydroxyl pawg. Tsis tas li ntawd, cov khoom siv kuj tseem tuaj yeem siv los ua cov khoom siv hauv kev lag luam rau kev tsim cov tshuaj tua kab mob, tshuaj tua kab mob antioxidants, thiab kev ua haujlwm siab polymerization inhibitors.
Nws ua lub luag haujlwm tseem ceeb hauv kev tsim cov organic, thiab nws cov phenolic hydroxyl pawg acidity thiab nucleophilicity ua rau nws yog ib qho tseem ceeb raw cov ntaub ntawv rau kev npaj catechol derivatives, uas yuav siv tau rau cov synthesis ntawm ntau yam phenolic bioactive molecules.
|
Tshuaj Formula |
C7H8O2 |
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Exact Mass |
124 |
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Molecular Luj |
124 |
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m/z |
124 (100.0%), 125 (7.6%) |
|
Elemental Analysis |
C, 67.73; H, 6.50; O, 25.78 |
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|
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Pharmaceutical Chemistry thiab Biopharmaceuticals
Kev kho mob plawv
Catechol qauv ntawm4-methylcatechol hmoovyog lub tseem ceeb pharmacophore ntawm adrenergic tebchaw xws li adrenaline thiab norepinephrine. Methyl hloov pauv tuaj yeem txhim kho molecular hydrophobicity thiab txhim kho pharmacokinetic zog.
Piv txwv kev tsom xam:
Compound A (Dobutamine Analog)
Synthesis txoj kev: 4-Methylcatecho yog nkag mus rau hauv pawg nitro los ntawm nitration cov tshuaj tiv thaiv, thiab txo kom tau 3,4-dihydroxyphenylethylamine skeleton, uas yog ces condensed nrog chloroacetyl chloride los tsim lub hom phiaj molecule.
Pharmacological teebmeem: Kev xaiv ua haujlwm ntawm - adrenergic receptors txhim kho myocardial contractility, nce plawv Performance index (CI) los ntawm 35% yam tsis muaj lub plawv dhia.
Cov txiaj ntsig kho mob: Methyl hloov pauv ua kom ntev plasma ib nrab- lub neej (t ²=3.2 h vs dobutamine 2.5 h) thiab txo cov koob tshuaj ntau zaus.
Compound B (alpha / beta receptor dual agonist)
Cov yam ntxwv ntawm cov qauv: catechol A yog ib puag ncig tus phooj ywg thiab khaws cia, thaum lub nplhaib B qhia txog methyl hloov pauv amino sab saw.
Pharmacological cov ntaub ntawv: Nyob rau hauv cov nas ex vivo txoj cai ventricular sim, qhov zoo inotropic nyhuv EC ₅₀=0.8 nM txo peripheral vascular resistance los ntawm 40%.
Kev loj hlob theem: Tam sim no nyob rau theem II soj ntsuam kev sim rau kev kho mob ntawm lub plawv tsis ua hauj lwm refractory.
Anti qog tshuaj tsim
Cov khoom siv redox ntawm catechol ua rau nws yog ib pab pawg zoo tshaj plaws rau kev tsim cov tshuaj prodrug, thiab kev hloov methyl tuaj yeem tswj hwm tus nqi ntawm cov tshuaj.
Piv txwv kev tsom xam:
Compound C (nitrogen mustard prodrug)
Mechanism ntawm kev txiav txim: 4-methylcatecho yog txuas nrog nitrogen mustard los ntawm thioether daim ntawv cog lus. Nyob rau hauv qhov kev txiav txim ntawm NADPH / CYP450 reductase, uas tau nthuav tawm heev hauv cov qog hlwb, thioether daim ntawv cog lus tau tawg kom tso tawm cov khoom siv nitrogen.
Kev ua hauv vitro: Rau ntau cov tshuaj tiv thaiv MCF-7/ADR cov qog nqaij hlav cancer mis, IC ∨ ₀=1.2 μ M, zoo dua li kev tswj tsis tau (IC ∨ ₀=8.9 μ M).
Hauv kev sim vivo: Hauv cov qauv qog cov kabmob nas, cov qog loj hlob inhibition tus nqi (TGI) mus txog 72%, thiab lub plawv toxicity qis dua li ntawm doxorubicin.
Compound D (Topoisomerase inhibitor)
Tus qauv tsim: Cov khoom thiab camptothecin yog txuas los ntawm ester bonds, siv cov acidic microenvironment rhiab heev ntawm catechol kom ua tiav lub hom phiaj tso tawm.
Qhov zoo: Tus nqi tso tawm hauv cov qog nqaij hlav (pH 6.5) yog 5 zaug sai dua li cov ntaub so ntswg (pH 7.4), txo cov kab mob toxicity.
Kev kho cov kab mob neurodegenerative
Simulate dopamine metabolism txoj hauv kev thiab tsim cov tebchaw nrog antioxidant thiab neuroprotective teebmeem.
Piv txwv kev tsom xam:
Compound E (GSH conjugate)
Synthesis lub tswv yim: 4-methylcatecho txuas nrog glutathione los ntawm disulfide daim ntawv cog lus, siv kev sib koom tes muaj peev xwm ntawm catechol los txhawb cov ntshav-hlwb barrier nkag mus.
Kev soj ntsuam kws tshuaj: Hauv MPTP induced Parkinson tus kab mob nas qauv, qhov ciaj sia taus ntawm dopaminergic neurons tau nce los ntawm 45%, thiab tus nqi rov qab ntawm lub cev muaj peev xwm sib koom ua ke mus txog 60%.
Mechanism: Compounds yog enriched nyob rau hauv astrocytes, txhawb txoj kev thauj mus los ntawm GSH mus rau neurons thiab inhibiting oxidative kev nyuaj siab.
Kev tshawb fawb txog tshuaj tiv thaiv kab mob
Cov hlau chelating muaj peev xwm ntawm catechol tuaj yeem cuam tshuam cov metabolic homeostasis ntawm cov kab mob pathogenic.
Piv txwv kev tsom xam:
Compound F (tus neeg sawv cev tiv thaiv kab mob)
Lub Hom Phiaj: Chelate Fe ³ ⁺ nyob rau hauv cov phab ntsa ntawm cov kab mob fungal, cuam tshuam cov membrane kev ncaj ncees, thiab ua rau cov ntsiab lus to.
Kev ua hauv vitro: MIC=0.5 μ g / mL tiv thaiv Candida albicans, tseem muaj txiaj ntsig zoo tiv thaiv kab mob fluconazole.
Hauv kev sim vivo: Hauv tus qauv nas ntawm cov kab mob candidiasis, qhov ciaj sia tau nce los ntawm 10% hauv pawg tswj hwm mus rau 65%.
Advanced functional khoom teb
Biomimetic nplaum cov ntaub ntawv
Kev sib koom tes muaj peev xwm ntawm pawg catechol (tsim tsib lub nplhaib chelates nrog cov hlau oxide nto) ua rau lawv zoo heev hauv cov ntaub nplaum hauv qab dej.
Piv txwv kev tsom xam:
Polymer G (hauv qab dej nplaum)
Synthesis method: 4-Methylcatecho yog copolymerized nrog acrylamide, thiab molecular hnyav tis yog tswj los ntawm RAFT polymerization (Đ=1.12).
Kev ua haujlwm tsis zoo: Lub zog hauv qab dej adhesion rau aluminium alloy nce mus txog 1.8 MPa (zoo dua li 0.8 MPa ntawm cov khoom lag luam epoxy resin), thiab cov ntsev tsuag tshuaj tiv thaiv ntau tshaj 500 teev.
Daim ntawv thov rooj plaub: Siv rau nkoj los tiv thaiv fouling txheej, nrog kev ua haujlwm ntawm 92% hauv kev tiv thaiv barnacles los ntawm adhering.
Hydrogel H (cov ntaub so ntswg nplaum)
Cov txheej txheem kev npaj: 4-methylcatecho hloov kho hyaluronic acid yog hla- txuas nrog Fe ³+ los ua tus kheej-kho dej gel.
Daim ntawv thov kev kho mob: Siv rau daim tawv nqaij kaw, nrog lub zog tawg ntawm 25 kPa thiab biocompatibility kuaj raws li ISO 10993 tus qauv.
Conductive Polymer Composite Materials
Raws li ib tug dopant, nws txhim kho cov txheej txheem thiab ib puag ncig stability ntawm conductive polymers.
Piv txwv kev tsom xam:
Composite Material I (Flexible Electrode)
Cov khoom muaj pes tsawg leeg: PEDOT: PSS sib xyaw nrog nws, npaj los ntawm kev daws txheej txheej.
Kev ua haujlwm hluav taws xob: Lub conductivity tseem nyob ntawm 120 S / cm, thiab lub zog tensile yog nce mus rau 45 MPa (pure PEDOT: PSS yog 18 MPa).
Daim ntawv thov ntaus ntawv: Siv rau kev hloov pauv supercapacitors, nrog lub zog ceev ntawm 8.7 Wh / kg thiab muaj peev xwm tuav tau ntawm 82% tom qab 1000 cycles.
Thermal rhiab heev cov ntaub ntawv J (kub responsive conductive nplaum)
Tsim qauv: Nws yog copolymerized nrog poly (N-isopropylacrylamide) (PNIPAm), siv lub redox teb ntawm catechol.
Cov yam ntxwv ntawm kev ua tau zoo: Ntawm 32 degree, kev hloov pauv sai sai (los ntawm 0.1 S / cm rau 15 S / cm), thiab cov lus teb ceev tsawg dua 1 s.
Optical functional khoom
UV absorption yam ntxwv ntawm catechol (λ _max{1}} nm) ua rau nws muaj peev xwm siv nyob rau hauv photoresist thiab photosensitive txheej.
Piv txwv kev tsom xam:
Photoresist K (microelectronic ua)
Formula muaj pes tsawg leeg: Epoxy resin / photoacid generator system muaj4-methylcatechol hmoov.
Lithography kev ua tau zoo: Nyob rau hauv 365 nm illumination, qhov tob curing ncav cuag 45 μ m, thiab qhov kev daws teeb meem zoo dua li kev lag luam SU-8 photoresist (kab dav<2 μ m).
Daim ntawv thov: Siv rau MEMS cov cuab yeej tsim khoom, nrog kev sib raug zoo ntawm kev sib raug zoo ntawm ± 0.1 μ m.
Photochromic txheej L (ntse ntim)
Cov txheej txheem hloov xim: 4-methylcatecho yog sib xyaw nrog spiropyran thiab ua rau cis trans isomerization tom qab UV irradiation, ua rau muaj xim hloov ntawm tsis muaj xim mus rau xiav.
Kev cia siab rau kev lag luam: Siv rau cov tshuaj txee lub neej cov ntawv qhia, nrog rau kev hloov xim ntawm qhov yuam kev tsawg dua 5%.
Agricultural Chemicals thiab Agricultural Technology
Fungicide Enhancer
Kev hloov pauv methyl txhim kho qhov permeability ntawm cov tebchaw hauv cov nroj tsuag cuticle thiab txhim kho kev ua haujlwm ntawm fungicides.
Piv txwv kev tsom xam:
Enhancer M (Azoxystrobin Companion)
Compound ratio: 4-methylcatecho thiab azoxystrobin yog compounded nyob rau hauv ib tug ratio ntawm 1: 5.
Kev sim teb: Kev tswj cov nyhuv ntawm dib downy mildew nce los ntawm 65% mus rau 88%, txo kev siv tshuaj tua kab los ntawm 30%.
Mechanism of action: Enhancers cuam tshuam kev ncaj ncees ntawm cov kab mob kab mob ntawm tes thiab txhawb nqa kev xa ntawm azoxystrobin mus rau lub hom phiaj.
Tshuaj tua kab mob kev nyab xeeb
Xaiv kev tiv thaiv cov qoob loo los ntawm kev puas tsuaj los ntawm tshuaj tua kab thiab txhim kho kev nyab xeeb ntawm qoob loo.
Piv txwv kev tsom xam:
Tus neeg saib xyuas kev nyab xeeb N (pob kws tshwj xeeb)
Cov qauv tshuaj: derivative ntawm 4-methylcatecho sulfonate.
Cov nyhuv: Thaum siv ua ke nrog nicotinuron, qhov ciaj sia taus ntawm cov pob kws cog qoob loo nce ntawm 30% mus rau 85%, thiab cov nroj tsuag tswj cov nyhuv tseem nyob ntawm 90%.
Biochemical mechanism: Inducing qoob loo GST enzyme kev ua thiab ua kom cov tshuaj tua kab mob metabolism hauv cov khoom tsis muaj tshuaj lom.
Cog kev loj hlob regulators
Simulate auxin kev ua ub no los txhawb kev loj hlob hauv paus thiab kev ntxhov siab.
Piv txwv kev tsom xam:
Regulator O (tshuaj tiv thaiv kev loj hlob txhawb nqa)
Synthesis method: 4-Methylcatecho yog txuas rau naphthylacetic acid los ntawm ester bonds.
Kev ua haujlwm lom neeg: Lub hauv paus cag ntom ntom hauv Arabidopsis tau nce 2.1 npaug, thiab tus nqi ciaj sia nyob rau hauv kev ntxhov siab ntxhov siab tau nce 40%.
Cov khoom lag luam: Sau npe ua cov chiv ntxiv, kev pom zoo noj yog 20-30 mg / L.
Tshuaj tua kab qeeb- tso tawm cov neeg ua haujlwm
Siv cov kev sib koom ua ke ntawm catechol thiab hlau ions kom ua tiav kev tso tawm.
Piv txwv kev tsom xam:
Extended tso tawm tus neeg saib xyuas P (avermectin cab kuj)
Kev npaj: 4-Methylcatecho hloov kho mesoporous silica nrog cov tshuaj thauj khoom ntawm 32%.
Cov yam ntxwv tso tawm: Tso ib nrab- lub neej ntawm 28 hnub hauv pH 5.5 av (simulating rhizosphere ib puag ncig), txo cov leaching poob.
Kev ntsuas kev ua tau zoo: Txuas ntxiv lub sijhawm ntawm kev tswj nematode los ntawm 40 hnub.
Organic synthesis thiab cov tshuaj zoo
Tag nrho cov synthesis ntawm natural khoom
Raws li ib tug tseem ceeb intermediate koom nyob rau hauv kev tsim kho ntawm complex molecules.
Piv txwv kev tsom xam:
Compound Q (tshuaj tiv thaiv -cov qog nqaij hlav natural khoom analogue)
Synthesis txoj kev: 4-Methylcatecho raug rau Diels Alder cov tshuaj tiv thaiv los tsim ib lub cev pob txha hydrogenated naphthalene, uas yog tom qab ntawd raug rau Baeyer Villiger oxidation thiab txo qis rov qab kom tau txais lub hom phiaj molecule.
Cov kauj ruam tseem ceeb: Lub xeev oxidation tswj ntawm catechol yuav tsum tsis tshua muaj kub (-78 degree) thiab nruj anhydrous tej yam kev mob, nrog ib tug yield ntawm 42%.
Kev ua haujlwm lom neeg: rau MDA-MB-231 mob qog noj ntshav mis IC ≮ ₀=0.3 μ M, cov txheej txheem ntawm kev ua haujlwm yog tubulin inhibitor.
Synthesis ntawm essence thiab tshuaj tsw qab
Kev hloov pauv methyl coj ib qho tshwj xeeb vanilla aroma nrog qhov pib qis thiab ntev - ntxhiab tsw.
Piv txwv kev tsom xam:
Spice R (Cream Aroma Hom)
Synthesis txoj kev:4-methylcatechol hmoovyog acetylated thiab xaiv txo kom tau 4-methylguaiacol.
Daim ntawv thov: Nws yog siv rau hauv cov mis nyuj mis, thiab 0.5-2 ppm tuaj yeem muab nplua nuj cream aroma.
Cov ntaub ntawv lag luam: Lub ntiaj teb kev thov txhua xyoo yog kwv yees li 800 tons, feem ntau yog siv rau cov khoom ci thiab dej khov.
Dye intermediates
Kev sib koom tes muaj peev xwm ntawm catechol yog siv rau kev sib txuas ntawm hlau complex dyes.
Piv txwv kev tsom xam:
Dye S (xim liab)
Synthesis method: 4-methylcatecho complexed nrog Cr ³ ⁺ nyob rau hauv acidic tej yam kev mob los tsim ib tug sib sib zog nqus liab dye.
Dyeing kev ua tau zoo: Cov xim ceev ceev rau dyeing wool npuag nce mus txog 4-5 qib, thiab lub hnub ceev nce mus txog 6 qib.
Environmental friendliness: Tsis muaj banned aromatic amines thiab ua tau raws li Oeko Tex Standard 100 tus qauv.
Cov ntaub ntawv siv lead ua kua
Raws li ib sab saw kua siv lead ua khoom, nws endows cov khoom nrog kub teb.
Piv txwv kev tsom xam:
Ua kua Crystal compound T
Molecular tsim: 4-methylcatecho txuas nrog cov cyanobiphenyl kua siv lead ua nucleus los ntawm cov pab pawg hloov tau yooj yim.
Theem hloov pauv tus cwj pwm: Clearing point =125 degree, kua siv lead ua theem kub ntau yam Δ T=42℃.
Daim ntawv thov: Siv rau cov lus qhia thermochromic nrog cov lus teb ceev ntawm<10 ms.
Analysis, Detection, thiab Sensors
Hlau ion detection
Lub fluorescence quenching zog ntawm catechol yog siv rau kev xaiv nrhiav kom tau cov hlau hnyav ions.
Piv txwv kev tsom xam:
Probe U (Fe ³ ⁺ kuaj pom)
Tsim qauv: Quantum dots hloov nrog 4-methylcatecho, nrog Fe ³ ⁺ quenching fluorescence los ntawm kev hloov hluav taws xob.
Performance parameters: detection limit of 0.5 nM, selectivity coefficient (Fe ³ ⁺/other metals)>100.
Daim ntawv thov tswv yim: Siv rau kev saib xyuas hauv online ntawm cov dej haus, nrog rau kev tshawb pom ntau zaus ib zaug txhua 5 feeb.
Biomolecular Sensors
Siv cov kev ua redox ntawm catechol txhawm rau txheeb xyuas cov tshuaj tiv thaiv enzymatic.
Piv txwv kev tsom xam:
Kev ntsuas ntshav qabzib (V Sensor)
Cov txheej txheem kev npaj: Electropolymerization ntawm 4-methylcatecho nyob rau saum npoo ntawm Prussian xiav hloov electrode.
Kev kuaj pom kev ua haujlwm: Linear ntau ntawm 0.1-10 mM, rhiab heev ntawm 12.5 μ A · mM ⁻¹· cm ⁻ ², lub sijhawm teb<3 s.
Daim ntawv thov kev kho mob: siv rau kev soj ntsuam hws qabzib ntawm cov neeg mob ntshav qab zib, nrog kev sib raug zoo coefficient R ²=0.992.
Environmental pollutant nrhiav pom
Kev sib koom tes muaj peev xwm ntawm catechol yog siv los kuaj cov pa phem xws li tshuaj tua kab organophosphorus.
Piv txwv kev tsom xam:
Reagent Kit W (rau kev kuaj pom oxygen phosphorus)
Reaction txoj cai: 4-methylcatecho tsim ib tug ntshav complex nrog Fe ³ ⁺, uas sib tw nrog oxygen phosphorus los ntawm phosphatase hydrolysis los tsim phenolic coordination tebchaw.
Kev kuaj pom qhov txwv: 0.1 μ g / L, haum rau kev tshuaj xyuas sai ntawm cov organic phosphorus residues hauv cov qauv zaub.
Tus qauv ntawm4-methylcatechol hmoovmuaj ob chav phenolic hydroxyl, uas muaj cov kua qaub muaj zog thiab tuaj yeem ua rau cov kua qaub -cov tshuaj tiv thaiv tsis zoo nrog cov tshuaj alkaline.
Nyob rau hauv cov xwm txheej alkaline, qhov sib xyaw no tuaj yeem raug hloov pauv nucleophilic cov tshuaj tiv thaiv nrog cov tshuaj alkyl halide sib xyaw kom tau txais cov khoom sib txuam ether. Vim yog txoj haujlwm nyob ib sab ntawm ob pawg hydroxyl ntawm lub nplhaib benzene, nws tuaj yeem siv los ua kom muaj cov tshuaj tsw qab ether sib txuas.
Dissolve nws (5.0 g, 40.28 mmol) nyob rau hauv N ntawm 0℃C nyob rau hauv ib tug qhuav cov tshuaj tiv thaiv hwj, N-dimethylformamide (DMF) tau ntxiv rau cov tshuaj tiv thaiv sib tov, tom qab ntawd ntxiv imidazole (13.7 g, 201.39 mmol) thiab t-butyldimethylformamide (DMF) 120.83 mmol) nyob rau hauv nitrogen. Rov qab tau cov tshuaj tiv thaiv sib tov rau hauv chav tsev kub thiab do cov tshuaj tiv thaiv thaum hmo ntuj ntawm chav tsev kub.
Tom qab ua tiav cov tshuaj tiv thaiv, ntxiv dej khov rau cov tshuaj tiv thaiv sib tov thiab muab rho tawm peb zaug nrog dichloromethane (3 × 150 mL). Muab tag nrho cov txheej txheem organic thiab ntxuav nrog cov kua NaCl saturated. Cais cov organic txheej thiab qhuav nws ntawm anhydrous sodium sulfate. Lim kom tshem tawm cov desiccant thiab mloog zoo rau qhov ua kom pom nyob rau hauv lub tshuab nqus tsev kom tau txais lub hom phiaj khoom molecule.
Nws yog ib qho zoo kawg nkaus sib xyaw nrog ntau hom kev siv hauv kev lag luam, tshuaj, thiab kev tshawb fawb ib puag ncig. Nws cov khoom siv tshuaj lom neeg tshwj xeeb, suav nrog kev ua haujlwm redox thiab hlau chelation, txhawb nqa nws cov txiaj ntsig hauv kev yees duab, plaub hau zas xim, thiab tswj kev ua qias tuaj. Lub caij no, nws cov dej num lom neeg-xws li tshuaj tua kab mob antioxidant, tiv thaiv- mob, thiab tshuaj tiv thaiv kab mob- qhia txog nws qhov peev xwm hauv kev kho mob.
Raws li kev tshawb fawb txuas ntxiv mus, cov txheej txheem kev sib txuas kom ruaj khov thiab cov ntawv thov tshiab (xws li nanotechnology, ntsuab chemistry) yuav nthuav dav ntxiv rau lub qab ntug ntawm 4-MC. Txawm li cas los xij, kev txiav txim siab txog kev nyab xeeb yuav tsum yog qhov tseem ceeb los xyuas kom meej lub luag haujlwm tuav thiab txo qhov cuam tshuam ib puag ncig.
Los ntawm kev tshawb nrhiav ntau lub luag haujlwm ntawm nws, cov kws tshawb fawb thiab kev lag luam tuaj yeem qhib lub sijhawm tshiab rau kev tsim kho tshiab thaum daws teeb meem thoob ntiaj teb hauv kev noj qab haus huv thiab kev ruaj ntseg.
1. Kev txheeb xyuas cov peev txheej ntuj nyob rau theem pib
Cov khoom, tseem hu ua homocatechol, tau pom thawj zaug hauv cov khoom ntuj thaum kawg ntawm lub xyoo pua 19th. Nws tshwm sim raws li ib qho kab hauv cov nroj tsuag xws li Norway spruce thiab tshuaj yej, nrog rau cov tsiaj zais cia nrog rau beaver castoreum. Hauv kev tshawb fawb thaum ntxov, nws tsuas yog suav tias yog ib qho me me phenolic metabolite, tsis muaj nyob hauv - qhov tob ntawm nws cov qauv thiab kev ua haujlwm.
2. Kev pom zoo ntawm cov qauv thiab tshuaj lom neeg
Los ntawm xyoo 1930 mus txog rau xyoo 1940, nrog rau kev nce qib ntawm cov thev naus laus zis tshuaj ntsuam xyuas, nws cov qauv tshuaj (4-methyl-1,2-benzenediol) tau raug txheeb xyuas. Thaum lub sijhawm xyoo 1950 thiab 1960, cov kws tshawb fawb pom tau tias nws cov tshuaj synthesis ntawm txoj hauv kev suav nrog methylation ntawm catechol thiab oxidation ntawm 4-methylguaiacol, tso lub hauv paus rau nws cov ntawv thov tom ntej.
3. Kev lees paub txog Kev Ua Si thiab Kev Ua Haujlwm Zoo
Txij li thaum xyoo 1970, nws tau raug lees paub tias yog lub plab hnyuv metabolite ntawm flavonoids xws li quercetin. Cov kev tshawb fawb tom qab tau maj mam txheeb xyuas nws ntau yam khoom xws li kev ua haujlwm antioxidant, cov nyhuv antiplatelet thiab muaj peev xwm ua rau lub hlwb ua rau lub hlwb- muab tau los ntawm neurotrophic factor (BDNF). Tam sim no nws tau dhau los ua qhov kev tshawb fawb hotspot hauv kev lag luam tshuaj thiab zaub mov.
FAQ
Cov qauv ntawm 4-Methylcatechol yog dab tsi?
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4-Methylcatechol yog ib qho organic compound nrog cov misCH3C 6H 3(OH)2Cov khoom dawb, nws yog ib qho ntawm cov isomers ntawm methylbenzenediol. Tsuas yog qhov uas tau sau tseg, cov ntaub ntawv raug muab rau cov ntaub ntawv hauv lawv lub xeev tus qauv (ntawm 25℃[77℃F], 100 kPa).
Dab tsi yog qhov solubility ntawm 4-Methylcatechol?
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4-Methylcatechol yog soluble hauv cov kuab tshuaj organic xws li ethanol, DMSO, thiab dimethyl formamide. Solubility ntawm 4-methylcatechol hauv cov kuab tshuaj no yog kwv yees li3, 20, thiab 25 mg / ml, raws.
Lwm lub npe rau 4-methylphenol yog dab tsi?
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P-Cresol
p-Cresol. para-Cresol, kuj 4-methylphenol, yog cov organic compound nrog cov mis CH3C6H4(OH). Nws yog cov khoom tsis muaj xim uas tau siv dav hauv nruab nrab hauv kev tsim khoom ntawm lwm yam tshuaj. Nws yog ib qho derivative ntawm phenol thiab yog ib qho isomer ntawm o-cresol thiab m-cresol.
Yuav ua li cas tshem tawm impurities ntawm thee?
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Feem ntau ntawm cov txheej txheem thee ntxuav sivupwards los yog pulses ntawm cov kua xws li dej kom fluidize lub txaj ntawm crushed thee thiab impurities. Cov khoom siv hluav taws xob sib zog tau nce thiab raug tshem tawm ntawm lub txaj saum txaj. Cov impurities hnyav dua raug tshem tawm hauv qab.
Cov tshuaj twg yog siv los ntxuav thee?
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MCHMyog ib qho tsis muaj xim ua npuas ncauj siv los ntxuav thee, tshem tawm impurities thiab cais nws los ntawm lwm yam khoom siv geological.
Cim npe nrov: 4-methylcatechol CAS 452-86-8, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom