Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm methylene xiav dye hmoov cas 61-73-4 hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo methylene xiav dye hmoov cas 61-73-4 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Methylene xiav dye hmoov, tseem hu ua methylene xiav, yog phenothiazine ntsev, CAS C16H18ClN3S, Cov tshuaj formula yog C16H18N3ClS. Nws yog glossy tsaus ntsuab bronze siv lead ua los yog hmoov. Nws yog qhov ruaj khov nyob hauv huab cua. Nws tsim complex ntsev nrog feem ntau inorganic ntsev, thiab nws cov kua aqueous yog alkaline thiab tshuaj lom. Soluble nyob rau hauv dej thiab ethanol, cov kua aqueous yog alkaline thiab insoluble hauv ether. Ntxiv dilute sulfuric acid rau methylene xiav kua yuav ua rau cov tshuaj kom ploj mus. Yog tias sai ntxiv rau ammonia lossis raug huab cua, nws tuaj yeem rov qab los thiab dav siv los ua cov cim tshuaj (methylene blue indicator), dye, biological dye, thiab tshuaj. Raws li cov dye class compounds, industrial qib methylene xiav feem ntau yog siv rau dyeing paj rwb, txhob lo lo ntxhuav, ntawv, thiab lwm yam. Nws kuj yuav siv tau nyob rau hauv coloring xyoob thiab ntoo, raws li zoo raws li tsim inks, xim pas dej, thiab lwm yam. Tsis tas li ntawd, nws yog feem ntau siv raws li ib tug kab mob stain, qhia, thiab lwm yam.
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Tshuaj Formula |
C16H18ClN3S |
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Exact Mass |
319 |
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Molecular Luj |
320 |
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m/z |
319 (100.0%), 321 (32.0%), 320 (17.3%), 322 (5.5%), 321 (4.5%), 323 (1.4%), 321 (1.4%), 320 (1.1%) |
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Elemental Analysis |
C, 60,08; H, 5,67; KL, 11.08; N, 13.14; S, 10.02 Nws |
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Melting point 190℃(dec.) (lit.), Ceev 1.0 g / mL ntawm 20℃C, Refractive index n20 / D1.347, flash point 45 degree, Cia txias chav temp, solubility nyob rau hauv dej, ethanol, ethylene glycol, methylid cellosolve coefficient 2.6,11.2 (ntawm 25 degree), Morphological Liquid, Xim Performance index 52015, Xim Ntsuab, Proportion 0.98, Odor (Odor) Odorless, Dej solubility 40 g / L (20 oC), Qhov siab tshaj plaws wavelength RN (6 λ), 3641570, Kev siv tshuaj tua kab mob microbial hauv thaj chaw lom neeg; ntshav qab zib retinopathy, macular degeneration, malignant uveal melanomas, erysipelas, hidradenitis obliteraa, o, kab mob ntawm daim tawv nqaij.
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Methylene xiav dye hmoov, tseem hu ua 3,7-bis (dimethylamino) phenothiazine-5-ium chloride trihydrate, yog ib qho tsaus ntsuab crystalline hmoov nrog lub bronze luster uas yooj yim soluble hauv dej thiab ethanol. Nws cov tshuaj aqueous zoo li xiav. Raws li cov xim hluavtaws nrog cov keeb kwm ntev, txij li nws thawj qhov sib xyaw ua ke hauv lub xyoo pua 19th, nws tau maj mam nthuav dav los ntawm kev luam ntawv textile thiab dyeing rau ntau yam kev qhuab qhia xws li aquaculture, kws tshuaj ntsuam xyuas, biochemistry, thiab lwm yam.
Aquaculture teb: "universal tshuaj" rau kev tiv thaiv kab mob thiab kev tswj dej zoo
1. Kev tiv thaiv thiab kho cov kab mob fungal
Nws yog cov tshuaj nyiam rau kev tiv thaiv thiab kho Saprolegniasis hauv aquaculture. Cov pwm dej yog tshwm sim los ntawm cov kab mob ntawm cov pwm dej genus, feem ntau pom nyob rau ntawm cov dej qis (10-18 degree). Tom qab cov ntses lub cev raug mob, fungal spores txuas rau lub qhov txhab, tsim cov paj rwb dawb zoo li hyphae. Thaum mob hnyav, nws tuaj yeem ua rau ntses lub cev rot thiab tuag. Los ntawm kev cuam tshuam cov permeability ntawm fungal cell membranes thiab inhibiting lawv cov metabolic kev ua si, tus kab mob tuaj yeem tswj tau zoo.
Daim ntawv thov Case:
Hauv kev ua liaj ua teb ornamental ntses, nws feem ntau yog siv rau kev kho cov ntses tshiab ua ntej nkag mus rau hauv lub tank. Soaking ntses lub cev hauv 0.1-0.2 ppm (mg / L) tshuaj methylene xiav rau 15-30 feeb tuaj yeem tua cov kab mob fungal thiab txo qhov kev pheej hmoo ntawm kev kis kab mob. Rau cov ntses muaj kab mob, tag nrho lub pas dej txau txoj kev tuaj yeem siv tau, siv 2-3 grams ntawm methylene xiav rau ib lub cubic meter dej, ib zaug ib hnub rau 2-3 zaug sib law liag, nrog kev kho tus nqi ntau dua 80%.
2. Kev kho kab mob parasitic
Nws muaj cov txiaj ntsig kho mob tseem ceeb ntawm cov kab mob parasitic xws li Ichthyophthoriasis thiab Trichodiniasis. Ichthyophthorius multifiliis yog ib tug loj protozoan parasite uas nws larvae burrow rau hauv daim tawv nqaij ntawm cov ntses los tsim cov vesicles dawb, ua rau khaus thiab txhuam ntawm phab ntsa hlab ntsha, thiab nyob rau hauv cov mob hnyav, cov kab mob thib ob. Los ntawm kev cuam tshuam nrog cov kab mob cab ua pa thiab inhibiting nws lub zog metabolism, nws tua cov cab.
Daim ntawv thov Case:
Thaum kho cov kab mob me me melon cab, qhov concentration ntawm methylene xiav tuaj yeem nce mus rau 0.3-0.5 ppm thiab txau thoob plaws hauv pas dej ua ke ib hnub rau 3-5 hnub sib law liag. Tib lub sijhawm nce qhov kub kom siab tshaj 30℃(raws li melon worms tsis tuaj yeem muaj sia nyob ntawm qhov kub thiab txias) tuaj yeem txo qhov kev kho mob. Rau cov kab mob cab cab, methylene xiav feem ntau ua ke nrog tooj liab sulfate los txhim kho cov nyhuv deworming.
3. Kev txhim kho dej zoo thiab tshem tawm cov tshuaj lom
Nws muaj cov khoom siv redox thiab tuaj yeem tswj cov oxidation -txo cov peev xwm (ORP) ntawm cov dej hauv lub cev, txhawb kev hloov pauv cov khoom tsis zoo xws li ammonia nitrogen thiab nitrite. Tsis tas li ntawd, nws tuaj yeem ua ke nrog cov hlau hnyav ions (xws li tooj liab thiab txhuas) hauv dej los tsim cov dej tsis sib haum, txo cov tshuaj lom.
Daim ntawv thov Case:
Hauv hom kev ua liaj ua teb hnyav, nws feem ntau siv los txo cov tshuaj lom nitrite.
Thaum lub concentration ntawm nitrite nyob rau hauv dej ntau tshaj 0.1 ppm, sprinkling methylene xiav ntawm ib koob ntawm 1 gram ib cubic meter ntawm dej yuav sai sai txo tau cov toxicity ntawm nitrite thiab yuav lub sij hawm rau hloov dej. Nyob rau tib lub sijhawm, cov xim xiav staining ntawm methylene xiav tuaj yeem ua rau kom pom tseeb ntawm cov dej hauv lub cev, ua rau nws yooj yim dua los saib xyuas cov xwm txheej ntawm cov ntses.
4. Kev tua kab mob thiab hatching txhawb nqa ntses qe
Nws tuaj yeem siv rau kev tua kab mob ntawm cov qe ntses kom tiv thaiv kab mob fungal thiab kab mob.
Nws cov tshuaj me me tsis ua rau ntses qe embryos, tab sis tsuas yog txhawb kev loj hlob ntawm embryo los ntawm kev txhim kho cov dej zoo (xws li nce cov pa oxygen ntau ntxiv).
Daim ntawv thov Case:
Hauv kev tsim cov ntses dej tshiab xws li carp thiab crucian carp, soaking cov qe qe ntses tshiab hauv 0.05 ppm methylene xiav tov rau 5 feeb tuaj yeem txhim kho qhov nce hatching. Rau cov qe nplaum (xws li cov qe ntses golden), cov tshuaj methylene xiav tuaj yeem txau mus rau hauv cov substrate txuas los tsim cov yeeb yaj kiab tiv thaiv thiab tiv thaiv cov kab mob fungal.
Kev kho mob: hla ciam teb daim ntawv thov los ntawm dyes mus rau txoj sia -txuag tshuaj
1. Ib qho tshuaj tiv thaiv tshwj xeeb rau methemoglobinemia
Methylene xiav dye hmoovNws yog ib qho mob ntshav uas tshwm sim los ntawm oxidation ntawm cov hlau ions hauv hemoglobin rau trivalent hlau (Fe ³ ⁺), uas ua rau poob ntawm cov pa oxygen thauj mus los. Tus neeg mob muaj cyanosis ntawm daim tawv nqaij thiab mucous daim nyias nyias, ua tsis taus pa nyuaj, thiab nyob rau hauv mob hnyav, coma los yog txawm tuag. Raws li tus neeg sawv cev txo qis, nws tuaj yeem txo cov methemoglobin mus rau ib txwm hemoglobin (Fe ² ⁺) thiab rov ua kom cov pa oxygen nqa.
Mechanism ntawm kev ua:
Txo kom "Leucomethylene Blue" hauv lub cev, uas ua raws li cov khoom siv hluav taws xob kom txo tau Fe ³ ⁺ hauv methemoglobin rau Fe ² ⁺. Nyob rau tib lub sijhawm, nws tuaj yeem ua rau NADPH dependent reductase system, ua kom cov metabolism hauv kev tshem tawm ntawm methemoglobin.
Clinical Case:
Xyoo 2023, kev sib tsoo nitrite tau tshwm sim hauv cov nroj tsuag tshuaj, thiab ntau tus neeg ua haujlwm tsim cov tshuaj methemoglobinemia tom qab nqus cov pa nitrite siab. Tus kws kho mob thaum muaj xwm txheej ceev tau tswj hwm 1% methylene xiav txhaj tshuaj (1-2 mg / kg lub cev qhov hnyav) tso rau hauv cov hlab ntsha, thiab tom qab 10 feeb, tus neeg mob cov tsos mob cyanosis zoo dua, thiab cov ntshav oxygen saturation rov qab mus rau qhov qub.
2. Cov tshuaj kho mob xwm txheej ceev rau kev lom tshuaj lom
Cyanide (xws li HCN, KCN) lom tuaj yeem ua rau muaj kev cuam tshuam ntawm cov kab mob hauv lub cev, ua rau cov ntaub so ntswg hypoxia. Methylene xiav txhawb kev sib xyaw ua ke ntawm cyanide thiab sodium thiosulfate los ua tsis yog - tshuaj lom thiocyanate los ntawm kev muab cov hluav taws xob, yog li tshem tawm toxicity.Mechanism of action:
Raws li cov khoom siv hluav taws xob, cyanide dissociated los ntawm cytochrome oxidase kom rov ua haujlwm enzyme.
Nyob rau tib lub sijhawm, nws tuaj yeem txhim kho cov nyhuv detoxification ntawm sodium thiosulfate, tsim "methylene blue sodium thiosulfate" kev sib xyaw ua ke.
Clinical Case:
Xyoo 2024, muaj qhov tshwm sim ntawm kev noj cov tshuaj potassium cyanide tshwm sim hauv tsev kawm ntawv kuaj mob, ua rau tus neeg mob tsis nco qab sai thiab muaj kev nyuaj siab ua pa. Pab neeg xwm txheej ceev tam sim ntawd tau txhaj tshuaj methylene xiav (5 mg / kg lub cev hnyav) ua ke nrog sodium thiosulfate (150-200 mg / kg lub cev hnyav), thiab tus neeg mob lub siab tsis nco qab maj mam rov zoo nrog cov cim tseem ceeb.
3. Tshuaj tua kab mob thiab tshuaj tua kab mob
Nws muaj qhov dav -spectrum antibacterial kev ua haujlwm thiab muaj kev cuam tshuam rau cov kab mob Gram zoo (xws li Staphylococcus aureus), Gram negative bacteria (xws li Escherichia coli), thiab qee cov fungi (xws li Candida albicans). Nws cov tshuaj tua kab mob muaj xws li cuam tshuam cov cell membrane qauv, inhibiting DNA replication, thiab cuam tshuam nrog lub zog metabolism.
Daim ntawv thov kev kho mob:
Kev kis kab mob hauv lub cev: Qhov ncauj methylene xiav (100-200 mg / hnub) lossis zais zis (0.1% tov) tuaj yeem siv los kho cystitis thiab urethritis, tshwj xeeb tshaj yog rau cov neeg mob uas tiv taus cov tshuaj tua kab mob.
Cov kab mob hauv qhov ncauj: Methylene blue mouthwash (0.05% concentration) tuaj yeem txo cov tsos mob xws li mob qhov ncauj thiab gingivitis, thiab txo cov kab mob colonization.
Cov kab mob ntawm daim tawv nqaij: Methylene blue ointment (1-2% concentration) tuaj yeem siv rau cov tawv nqaij kub hnyiab, mob plab, thiab lwm yam, txhawm rau tiv thaiv kab mob thiab txhawb kev kho mob.
4. Cov ntsuas ntsuas rau lub raum kev ua haujlwm
Methylene xiav tau tawm sai sai los ntawm ob lub raum tom qab nqus tau hauv lub cev, thiab nws qhov kev tso tawm yog ze ze rau glomerular filtration rate (GFR). Los ntawm kev ntsuas qhov kev hloov pauv ntawm cov tshuaj methylene xiav hauv cov zis, lub raum kev ua haujlwm tuaj yeem raug ntsuas ncaj qha.
Txoj kev kuaj:
Tom qab txhaj tshuaj methylene xiav (1 mg / kg lub cev qhov hnyav), cov zis tau sau nyob rau hauv ib ntus los ntsuas lawv qhov nqus los yog fluorescence siv thiab xam qhov tshem tawm.
Qhov kev tshem tawm ib txwm ntawm methylene xiav rau cov neeg laus yog 100-150 ml / min, thiab nws txo qis hauv cov neeg mob lub raum tsis ua haujlwm.
5. Cov tshuaj muaj peev xwm los tiv thaiv -kev tshawb nrhiav mob qog noj ntshav
Nyob rau hauv xyoo tas los no, nws tau pom muaj txiaj ntsig tshwj xeeb hauv kev kho mob qog noj ntshav. Nws txoj kev kho photodynamic (PDT) tuaj yeem ua haujlwm los ntawm cov lasers tshwj xeeb los tsim cov pa oxygen reactive xws li singlet oxygen, xaiv tua cov qog hlwb. Tsis tas li ntawd, nws tuaj yeem cuam tshuam cov qog angiogenesis thiab thaiv cov khoom noj khoom haus.
Kev tshawb fawb nce qib:
Xyoo 2025, ib pab neeg tau tshaj tawm cov kev tshawb fawb hauv Nature Medicine, uas tau lees paub tias methylene xiav nanoparticles (MB NPs) tuaj yeem xa mus rau cov ntaub so ntswg. Los ntawm kev sib koom ua ke ntawm cov nyhuv photothermal thiab kev kho tshuaj kinetic, lawv tuaj yeem cuam tshuam kev loj hlob ntawm cov qog nqaij hlav hauv lub mis hauv nas, thiab muaj toxicity tsawg heev rau cov ntaub so ntswg.
Methylene xiav dye hmoov, raws li ib tug ntoo khaub lig-xyoo pua 'xiav txuj ci tseem ceeb', tau pom qhov sib sib zog nqus kev koom ua ke ntawm chemistry thiab life sciences nyob rau hauv nws daim ntawv thov keeb kwm.
Los ntawm txuag cov tsiaj hauv dej kom txuag tib neeg lub neej, los ntawm cov chaw ua haujlwm dyeing mus rau chav ua haujlwm, qhov sib xyaw ua ke no tseem ci ntsa iab nrog kev tshawb fawb zoo nkauj, ua rau muaj txiaj ntsig zoo rau tib neeg kev noj qab haus huv thiab kev loj hlob.
FAQ
methylene xiav dye siv rau dab tsi?
Methylene xiav yog ntsev thiab zas xim nrog antioxidant, tiv thaiv -inflammatory, antidepressant thiab analgesic zog. Nws tau siv rau hauv cov tshuaj rau ntau tshaj 100 xyoo hauv tshuaj loog, gastroenterology, pathology, histology thiab tshuaj kho mob.
Puas yog methylene xiav dye teeb meem?
Methylene Blue Toxicity
Nws tsis yog ib yam rau methylene xiav ua rau muaj kev tsis haum tshuaj loj. Serotonin syndrome tuaj yeem ua rau tuag taus, uas yog vim li cas cov kws kho mob tsis siv methylene xiav nrog rau cov tshuaj uas suav nrog lossis nce serotonin, xws li qee yam tshuaj tiv thaiv kev nyuaj siab.
Puas yog methylene xiav ok noj txhua hnub?
Cov khoom no feem ntau thov kom txhawb zog, txhim kho kev nco, lossis txhawb kev noj qab haus huv. Tab sis cov kws tshaj lij tsis pom zoo tias tib neeg noj tshuaj methylene xiav tshuaj. Ua ntej tshaj plaws, nws tuaj yeem ua rau muaj kev phom sij txaus ntshai thiab teeb meem kev noj qab haus huv loj.
Cim npe nrov: methylene xiav dye hmoov cas 61-73-4, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom