Txhawm rau kho mob ntshav qab zib hom 2, peb xav tau cov tswv yim tshiab uas ua haujlwm ntawm ntau tshaj ib txoj kev metabolic nyob rau tib lub sijhawm. Cov bioglutide nrog -931 peptide hmoovs dual-txoj kev ua haujlwm, uas cuam tshuam rau ob qho tib si tswj cov piam thaj thiab insulin rhiab heev, yog ib txoj hauv kev tshiab los kho ntshav qab zib. Cov neeg ua haujlwm hauv chaw muag tshuaj thiab kws kho mob uas xav nrhiav txoj hauv kev zoo dua los pab cov neeg uas muaj teeb meem tswj lawv cov ntshav qab zib kom txaus siab rau cov peptide no -raws li cov khoom siv. Ntau tshaj li ob lab tus tib neeg thoob ntiaj teb muaj ntshav qab zib hom 2. Tam sim ntawd, peb xav tau kev kho mob uas dhau mus dhau ib qho - txoj hauv kev. Muaj cov txheej txheem nyuaj uas cia cov bioglutide na-931 peptide ua nws txoj haujlwm. Nws hloov mus rau ob qho tib si GLP-1 thiab GIP receptors, uas muaj ntau yam teebmeem ntawm lub cev. Cov kws tshawb fawb, cov tuam txhab tshuaj, thiab cov neeg ua haujlwm saib xyuas kev noj qab haus huv tuaj yeem txiav txim siab seb qhov peptide no yuav tsum siv rau hauv cov phiaj xwm tswj ntshav qab zib yog tias lawv paub tias nws ua haujlwm li cas.
Tam sim no peb yuav tham txog yuav ua li cas bioglutide na-931 peptide ua haujlwm, nws cov txiaj ntsig zoo li cas, thiab nws tuaj yeem siv li cas los pab kho mob ntshav qab zib hom 2 hauv lub neej tiag tiag. Cov khoom no muaj ntau lub peev xwm los kho hauv ntau qhov sib txawv, los ntawm ntshav qab zib mus rau cov txheej txheem metabolic.
1. General Specification (hauv Tshuag)
(1) API (Ntshiab hmoov)
PE / Al foil hnab / ntawv lub thawv rau cov hmoov ntshiab
(2) Spot-On
(3) Kev daws teeb meem
(4) Poob
2.Customization:
Peb yuav sib tham tus kheej, OEM / ODM, Tsis muaj hom, rau kev tshawb nrhiav kev ruaj ntseg nkaus xwb.
Khoom siv: BM-1-154
TIAB SA-931
Kev tshuaj xyuas: HPLC, LC-MS, HNMR
Kev them nyiaj yug Technology: R & D Dept.-3
Peb muab Bioglutide NA-931, thov xa mus rau lub vev xaib hauv qab no kom paub meej cov lus qhia thiab cov khoom lag luam.
Khoom siv:https://www.bloomtechz.com/synthetic-chemical/peptide/bioglutide-na-931.html
Yuav ua li casbioglutide nrog -931 Peptide txhawb kev tswj ntshav qabzib hauv ntshav qab zib hom 2
Dual{0}}Receptor Activation Mechanism
Los ntawm ib qho tshwj xeeb dual -cov txheej txheem agonist, bioglutide na-931 peptide ua haujlwm los ntawm ib txhij koom nrog glucagon-zoo li peptide-1 receptors thiab qabzib-dependent insulinotropic polypeptide receptors. Ua ke, kev ua ub no zoo rau pancreatic beta hlwb vim lawv paub ntau ntxiv txog kev hloov pauv hauv cov ntshav qab zib. Tsis zoo li cov tshuaj uas tsuas yog kho ib feem ntawm cov piam thaj dysregulation uas ua rau mob ntshav qab zib hom 2, txoj kev no daws tau ob qho tib si.Vim tias txoj kev nws cov molecules zoo li qub, peptide tuaj yeem khi rau ob hom receptors. Qhov no pib qhia txoj hauv kev hauv cov hlwb uas nce qib insulin hauv txoj hauv kev uas nyob ntawm qib qabzib.
Hypoglycemia tsis tshua muaj tshwm sim nrog cov piam thaj no - nyob ntawm cov txiaj ntsig zoo dua li lwm cov tshuaj ntshav qab zib. Cov kws kho mob tau pom tias tib neeg ntawm ob- kev kho mob agonist muaj cov ntshav qab zib nyob hauv ib hnub ntau dua li cov tib neeg ntawm ib leeg - cov tshuaj siv tshuaj.
Enhanced Pancreatic Beta Cell Function
bioglutide nrog -931 peptide uaTej zaum yuav pab tiv thaiv thiab ua haujlwm pancreas beta hlwb, uas poob lawv lub peev xwm ua lawv txoj haujlwm dhau sijhawm hauv cov neeg mob ntshav qab zib hom 2.Qhov no yuav pab txiav txiav ua cov tshuaj insulin vim tias peptide ua rau cov beta hlwb loj hlob thiab txwv tsis pub lawv tuag.
bioglutide nrog -931 Peptide rau Kev Txhim Kho Insulin Response thiab Metabolic Control
Restoration ntawm Thawj -Phase Insulin Response
Cov neeg mob ntshav qab zib hom 2 feem ntau poob qhov thawj -theem insulin teb. Qhov no yog thaum cov tshuaj insulin nce sai sai hauv feeb ntawm cov piam thaj nce ntxiv. bioglutide na-931 peptide tau pom tias muaj peev xwm los kho cov tshuaj insulin thaum ntxov. Qhov no pab nres qhov kev hloov pauv txaus ntshai hauv cov ntshav qab zib uas tshwm sim tom qab noj mov. Rov qab mus rau cov qauv ntawm cov tshuaj tiv thaiv no ua rau cov piam thaj tswj tau zoo dua nyob rau hauv dav dav thiab txo qis cov qib ntawm cov piam thaj.Peptide ua rau nws muaj peev xwm ua kom muaj cov kua dej insulin ntau dua kom tso tawm sai sai ntawm beta hlwb. Qhov no cia insulin nkag mus rau lub cev sai sai thaum nws xav tau.
Nws yooj yim dua rau cov kab mob peripheral kom noj cov piam thaj thaum thawj - cov tshuaj tiv thaiv theem nrawm dua. Qhov no txwv tsis pub lub siab ua rau cov piam thaj tsis zoo. Glucose tolerance tests ua los ntawm IV pom tau tias cov neeg uas tau muab ob npaug rau -agonist peptides muaj cov tshuaj insulin tso tawm sai dua.
Hepatic Glucose Production Suppression
Cov neeg mob ntshav qab zib hom 2 tau yoo mov hyperglycemia thaum lawv lub siab ua rau cov piam thaj ntau dhau. bioglutide na-931 peptide tuaj yeem pab daws qhov teeb meem no hauv ntau txoj hauv kev, suav nrog los ntawm kev txhawb nqa cov tshuaj insulin thiab hloov lub siab ua haujlwm ncaj qha.
Ua taubioglutide nrog -931 Peptide Pab txo qis tom qab- Noj Qab Zib Qab Zib Spikes?
Nthuav plab hnyuv Emptying nyhuv
Ib qho ntawm cov haujlwm tseem ceeb uasbioglutide nrog -931 peptide uapuas yog pab zaub mov txav mus rau hauv lub plab system. Vim tias peptide ua rau nws siv sijhawm ntev rau lub plab khoob, cov as-ham tsis nkag mus rau hauv cov hlab ntsha sai sai tom qab noj mov. Vim tias cov as-ham tau noj qeeb dua, cov piam thaj hauv cov ntshav nce qeeb dua. Qhov no tiv thaiv cov ntse spikes uas tshwm sim tom qab noj mov uas ntxhov siab pancreatic beta hlwb thiab ua rau cov hlab ntsha ua haujlwm tsis zoo.Peptides tig rau cov receptors hauv plab cov leeg nqaij thiab cov hlab ntsha hauv plab.
Qhov no ua rau lub plab siv sij hawm ntev kom khoob. Ua qhov kev txav no tsis txwv cov khoom noj los ntawm kev noj; nws tsuas yog kis lawv tawm mus ntev dua. Cov neeg mob hais tias lawv hnov qab ntev dua tom qab noj mov, uas tuaj yeem pab lawv taug qab pes tsawg calories lawv noj thiab tsis txhob tshaib plab.
Txhim kho Incretin nyhuv
Thaum cov piam thaj raug coj los ntawm qhov ncauj es tsis txhob muab ncaj qha, lub cev ua rau insulin ntau dua.Qhov txiaj ntsig no hu ua "incretin effect."
Cov neeg mob ntshav qab zib hom 2 muaj qhov tsis muaj zog incretin, uas ua rau hyperglycemia tom qab noj mov tsis zoo. Los ntawm kev ua rau incretin receptors sab nraum lub cev los tsim kom muaj qhov tsis txaus hauv lub cev, bioglutide na-931 peptide kho thiab txhim kho cov nyhuv incretin.Nws ua rau txoj hauv kev incretin muaj zog, uas ua kom cov piam thaj nce hauv txoj hauv kev tom qab noj mov. Lub cev muaj peev xwm tswj tau cov carbs nws noj tom qab kho qhov no, yog li cov piam thaj tsawg dua tom qab noj mov. Txoj hauv kev tseem ceeb uas ob-agonist peptides pab tswj cov ntshav qab zib tom qab noj mov yog los ntawm kev ua kom muaj zog incretin.
Yuav ua li casbioglutide nrog -931 Peptide Ua ke GLP-1R thiab GIPR Txoj Kev rau Glucose Balance
Synergistic Receptor Interaction
Ob leeg GLP-1 thiab GIP receptors ib txhij ua haujlwm los ntawm bioglutide na-931 peptide. Qhov no muaj cov teebmeem uas muaj zog tshaj qhov sib npaug ntawm kev ua haujlwm ntawm txhua txoj kev. Cov kws tshawb fawb hais tias kev ua kom GIPR ua rau cov teebmeem ntawm GLP-1R ua kom txo qis insulin ntau dua, tshwj xeeb tshaj yog thaum cov piam thaj ntau. Qhov no ua haujlwm ua ke txo qis cov piam thaj ntau dua li txoj hauv kev uas tsuas yog ua haujlwm nrog ib tus agonist.
Molecularly, qhov kev sib cuam tshuam no tshwm sim los ntawm kev taw qhia txoj hauv kev uas ua haujlwm ua ke hauv beta hlwb thiab muaj zog dua thaum ob qho tib si receptors raug qhib tib lub sijhawm.Los ntawm kev sib tham ntawm receptor systems, ntau cyclic AMP yog ua, thiab calcium txav mus los. Cov no yog cov cim tseem ceeb hauv cov hlwb uas ua rau insulin granules raug tso tawm. Qhov kev nkag siab ntawm cov khoom muaj sia no txhais tau hais tias cov qib qabzib tuaj yeem tswj tau zoo dua nrog tej zaum tsawg dua peptide.
Complementary Metabolic Effects
Kev ua kom GLP-1R feem ntau ua rau insulin tso tawm thiab tsis tshaib plab. Kev ua kom GIPR, ntawm qhov tod tes, muaj lwm cov txiaj ntsig metabolic, xws li cov roj metabolism zoo dua thiab kev paub txog zaub mov. Ob txoj hauv kev no kho ntau tshaj ib qho teeb meem tshuaj nyob rau tib lub sijhawm nyob rau hauvbioglutide nrog -931 peptide ua. Qhov no ua rau cov tshuaj ua haujlwm zoo dua nyob ib puag ncig.Tus dual- txoj kev agonist siv qhov zoo tshaj plaws ntawm ob txoj hauv kev thiab kuj tseem tuaj yeem ua rau cov ntsiab lus tsis muaj zog ntawm txhua txoj hauv kev. Thaum GLP-1 yuav tsis ua haujlwm zoo li, tig rau GIPR khaws cov txiaj ntsig zoo. Nrog rau cov kauj ruam ntxiv no, kev tswj cov piam thaj ntau ruaj khov rau ntau pab pawg neeg mob uas muaj qhov sib txawv ntawm incretin system tsis ua haujlwm.
Vim li casbioglutide nrog -931 Peptide txhawb kev sib koom ua ke ntshav qab zib thiab tswj qhov hnyav
Central Appetite Regulation
bioglutide na-931 peptide rhuav tshem cov ntshav- lub hlwb thaiv thiab nkag mus rau qhov chaw ntawm lub hlwb thiab qaum qaum uas tswj kev tshaib plab thiab ua kom lub zog sib npaug. Lub hypothalamus thiab lub paj hlwb muaj GLP-1 receptors uas, thaum qhib, nres cov teeb liab uas ua rau koj tshaib plab thiab puv. Qhov no cia li pab cov neeg poob phaus. Nws yog ib qho nyuaj rau cov neeg mob ntshav qab zib hom 2 kom lawv qhov hnyav hauv kev kuaj xyuas. Cov txiaj ntsig tseem ceeb no pab nrog qhov ntawd. Kev hloov pauv hauv pro-opiomelanocortin neurons thiab lwm txoj hauv kev uas tswj kev tshaib plab yog dab tsi ua rau koj xav tias tsis tshaib plab. Cov neeg mob hais tias lawv tsis xav tias tshaib plab thaum noj mov thiab noj zaub mov ntau dua thaum lub sijhawm noj mov, uas pab lawv ua raws li lawv txoj kev npaj noj.
Txhim khu kev siv zog
bioglutide na-931 peptide tuaj yeem hloov pauv lub zog koj siv ntau npaum li cas los ntawm kev hloov koj cov metabolism thiab cov nqaij rog xim av. Nws kuj ua rau koj xav tias tsis tshaib plab. Thaum koj tig rau incretin receptors hauv cov ntaub so ntswg rog, thermogenesis nrawm. Qhov no txhais tau tias txawm tias koj tsis ua dab tsi, koj hlawv calorie ntau ntau. Ua raws li ob kauj ruam no noj tsawg thiab txav mus ntxiv yuav pab koj poob phaus yooj yim dua.Thaum koj sim poob phaus, koj cov metabolism hloov pauv. Kev nce lub zog koj siv tuaj yeem pab nres qhov kev hloov pauv no. Ua kom koj cov metabolism hauv siab thaum koj tab tom sim poob phaus pab koj kom koj lub cev lean thiab tshem tawm cov rog sai dua.
Adipose ntaub so ntswg Remodeling
Adipocytes hloov ntau tshaj ib txoj kev los ntawm peptide. Nws txo qis ntawm cov ntaub so ntswg qhov loj thiab kev noj qab haus huv. Txhawm rau ua kom cov nqaij rog ntau dua rau cov tshuaj insulin, txoj hauv kev incretin tau qhib. Qhov no ua rau cov kab mob o poob qis, thiab qib adipokine txhim kho. Kev hloov pauv li cas cov ntaub so ntswg ua haujlwm ua rau koj cov metabolism hauv ntau dua li ib qho, uas yog vim li cas koj poob phaus.Thaum cov ntaub so ntswg rog noj qab haus huv, nws hloov mus rau hauv lub cev uas ua haujlwm zoo li cov metabolism thiab pab khaws cov piam thaj hauv cov tshuaj es tsis txhob muab pov tseg. Kev tshem tawm cov kab mob adipokines xws li interleukin-6 thiab qog necrosis yam tseem ceeb-alpha pab tshem tawm cov kab mob qis uas nyob ntev ntev thiab ua rau cov tshuaj insulin tsis kam mus.
Xaus
bioglutide nrog -931 peptide uayog ib txoj hauv kev nyuaj los kho mob ntshav qab zib hom 2. Nws ua haujlwm nrog ob qhov sib txawv receptors tib lub sijhawm los kho ntau yam teeb meem ntawm lub cev. Nws tuaj yeem nce qib insulin, ua kom cov tshuaj insulin ua haujlwm zoo dua, txo cov piam thaj hauv cov ntshav tom qab noj mov, thiab pab tswj qhov hnyav, ua rau peptide kev kho mob metabolic tag nrho. Nws muaj kev nyab xeeb heev vim tias nws cov teebmeem ntawm insulin tso siab rau qib qabzib. Qhov no txo qis txoj kev pheej hmoo ntawm hypoglycemia thaum tseem tswj cov piam thaj kom zoo.Thaum koj qhib ob qho tib si GLP-1R thiab GIPR txoj hauv kev tib lub sijhawm, koj tau txais txiaj ntsig ntau dua li thaum koj tsuas qhib ib txoj hauv kev xwb. Qhov no ua rau muaj kev cia siab rau cov neeg uas tsis muaj peev xwm tswj hwm lawv cov kev kho mob ib txwm muaj. bioglutide na-931 peptide xav tias yuav dhau los ua qhov tseem ceeb hauv kev tswj ntshav qab zib vim tias muaj kev tshawb fawb ntau ntxiv kom nkag siab tias nws siv li cas hauv lub cev. Peb xav tau cov neeg koom tes tsim kev ntseeg siab thiab siab - cov tshuaj tshawb fawb-qib zoo kom ua cov tshuaj peptide-raws li ntshav qab zib kom zoo dua thiab siab dua. Peptides uas muaj kev nyab xeeb rau kev siv tshuaj thiab tuaj nrog cov ntaub ntawv tshawb fawb tag nrho cia tib neeg ua ntau yam kev tshawb fawb thiab ua haujlwm ntawm cov khoom tshiab. Cov tuam txhab uas xav ua cov tshuaj ntshav qab zib kom zoo tuaj yeem ua tau zoo dua yog tias lawv ua haujlwm nrog cov neeg muag khoom uas paub yuav ua li cas kom raug.
FAQ
1. Ua dab tsibioglutide nrog -931 peptide txawv ntawm cov tshuaj noj ntshav qab zib li cas?
bioglutide na-931 peptide txawv ntawm lwm cov tshuaj ntshav qab zib vim nws ua haujlwm ntawm ob lub receptors sib txawv tib lub sijhawm. Feem ntau, kev kho mob tsuas yog tsom rau ib txoj hauv kev, xws li kev noj cov piam thaj, tso tawm insulin, lossis kev nkag siab ntawm insulin. Nws ua li cas los xij, tig rau ob qho tib si GLP-1 thiab GIP receptors tib lub sijhawm. Qhov kev nqis tes no yog tsim los ntawm ob feem uas ua haujlwm ua ke los pab nrog ntau yam ntawm hom 2 mob ntshav qab zib tib lub sijhawm. Cov no suav nrog kev tso tawm insulin, tiv thaiv insulin, txo kev tshaib kev nqhis, thiab ua kom lub cev hnyav. Txoj kev pheej hmoo ntawm hypoglycemia tsawg dua nrog cov tshuaj uas ua rau cov tshuaj insulin tso tawm, txawm hais tias qib qabzib yog dab tsi, vim tias lawv cov teebmeem nyob ntawm qib qabzib.
2. Ua li casbioglutide nrog -931 peptide cuam tshuam qhov hnyav hauv cov neeg mob ntshav qab zib hom 2?
Muaj ntau txoj hauv kev uas peptide hloov lub cev hnyav uas txhua tus ua haujlwm ua ke. Thaum koj qhib GLP-1 receptors hauv qhov chaw ntawm koj lub hlwb uas tswj kev tshaib kev nqhis, koj xav tias zoo dua thiab tshaib plab. Qhov no ua rau koj noj tsawg calorie ntau ntau. Cov peptide kuj tseem tuaj yeem hloov koj cov metabolism thiab thermogenesis, uas tuaj yeem ua rau koj siv zog ntau dua. Vim tias koj lub plab tsis khoob sai li sai tau, koj hnov qab ntev dua tom qab noj mov. Tag nrho cov txiaj ntsig no pab tib neeg kom poob phaus, uas, ntawm nws tus kheej, ua rau insulin ua haujlwm zoo dua thiab tswj cov qib qabzib zoo dua. Cov neeg mob ntshav qab zib hom 2 uas noj tshuaj raws li incretins yuav poob phaus qeeb tab sis tsis tu ncua dhau sijhawm. Nyob rau tib lub sij hawm, qhov no pab lawv digestive noj qab haus huv.
3. Qhov kev txiav txim siab zoo li cas yog qhov tseem ceeb thaum muab khoombioglutide nrog -931 peptide rau kev tshawb fawb?
Rau kev tshawb fawb vim li cas, peb xav tau cov kws kho mob - qib peptides uas tau sim rau purity thiab feem ntau qhia ib qib siab dua 98%, raws li qhia los ntawm HPLC tsom xam. Mass spectrometry, amino acid tsom xam, thiab ntsuas peptide cov ntsiab lus yog qee qhov kev sim tshuaj chemical uas siv los xyuas cov khoom zoo thiab xyuas kom meej tias txhua pawg yog tib yam. Yog tias koj xav khaws cov purity ntawm peptides thaum lub sij hawm kawm tej yaam num, koj yuav tsum muaj qhov chaw cia thiab ruaj ntseg cov ntaub ntawv. Pepsins tsuas yog siv tau rau hauv kev tshawb fawb soj ntsuam yog tias lawv los ntawm GMP-cov chaw kuaj pom zoo nrog cov ntaub ntawv raug, xws li kev tshawb fawb ruaj khov, tuav cov ntaub ntawv, thiab daim ntawv pov thawj ntawm kev tshuaj xyuas. Kev tshawb fawb- qib peptides yuav tsum ua tau raws li cov qauv siab uas xav tau los hloov cov tshuaj ntshav qab zib los ntawm lub chaw kuaj mob mus rau lub tsev kho mob. Qhov no tsuas yog ua tau los ntawm kev ua haujlwm nrog cov peev txheej uas paub txog yam xav tau rau kev tsim kho tshuaj thiab tuaj yeem muab kev pabcuam.
Koom tes nrog BLOOM TECH rau hwmbioglutide nrog -931 Peptide Supply
Rau kev pab nrog koj cov kev tshawb fawb thiab kev txhim kho, BLOOM TECH muajbioglutide nrog -931 peptide uauas yog tsim los siv kho mob. bioglutide na-931 peptide cov kws kho mob zoo li peb paub tias nws tseem ceeb npaum li cas rau cov tshuaj uas tsim los ntawm peptides kom huv, zoo ib yam, thiab ua raws li cov cai. Peb cov nroj tsuag uas muaj GMP-certified tau ua tib zoo xyuas los ntawm EU, US FDA, thiab PMDA. Qhov no ua kom paub tseeb tias txhua pawg ua tau raws li lub ntiaj teb cov qauv nruj tshaj plaws rau cov tshuaj. Peb tuaj yeem muab cov ntaub ntawv pov thawj tag nrho rau koj txoj kev kawm thiab cov ntaub ntawv tswj xyuas. Qhov no suav nrog HPLC, huab hwm coj spectrometry, thiab daim ntawv pov thawj ntawm kev tshuaj xyuas uas tshwj xeeb rau txhua pawg.
Peb cov neeg ua haujlwm txawj tshaj lij tuaj yeem ua txhua yam los ntawm pawg kawm me me mus rau kev tsim khoom loj. Peb muaj cov nqi meej thiab kev tswj xyuas zoo ntawm cov saw hlau. BLOOM TECH muab koj cov haujlwm ua haujlwm zoo, kev ntseeg siab, thiab kev pab cuam uas lawv xav tau, txawm tias koj ua haujlwm rau lub tuam txhab tshuaj uas ua tshuaj rau ntshav qab zib, pab pawg kawm uas saib mus rau hauv cov txheej txheem metabolic, lossis CDO uas ua haujlwm nrog cov neeg mob ntshav qab zib. Yog tias koj xav tau bioglutide na-931 peptide, thov xa email rau peb pab neeg ntawmSales@bloomtechz.comtam sim ntawd. Peb tuaj yeem pab koj ua kom lub sijhawm nws siv los ua kev tshawb fawb txog ntshav qab zib thiab ua cov khoom tshiab.
Cov ntaub ntawv
1. Finan B, Müller TD, Clemmensen C, et al. Reappraisal of GIP Pharmacology for Metabolic Diseases. Trends in Molecular Medicine, 2016, 22(5): 359-376.
2. Holst JJ, Rosenkilde MM. GIP raws li Kev Kho Mob Lub Hom Phiaj hauv Mob Ntshav Qab Zib thiab Kev rog: Kev Pom Zoo Los ntawm Incretin Co-agonists. Phau ntawv Journal of Clinical Endocrinology thiab Metabolism, 2020, 105(8): e2710-e2716.
3. Nauck MA, Quast DR, Wefers J, Meier JJ. GLP-1 Receptor Agonists hauv Kev Kho Mob Ntshav Qab Zib Hom 2 - Lub Xeev- ntawm -the-Art. Molecular Metabolism, 2021, 46: 101102.
4. Müller TD, Finan B, Bloom SR, et al. Glucagon-zoo li Peptide 1 (GLP-1). Molecular Metabolism, 2019, 30: 72-130.
5. Campbell JE, Drucker DJ. Pharmacology, Physiology, thiab Mechanisms ntawm Incretin Hormone Action. Cell Metabolism, 2013, 17(6): 819-837.
6. Frias JP, Nauck MA, Van J, et al. Kev ua tau zoo thiab kev nyab xeeb ntawm Dual GIP thiab GLP-1 Receptor Agonism hauv Hom 2 Ntshav Qab Zib: Kev Ntsuam Xyuas Kev Ntsuas thiab Meta-Tshawb. Diabetes Care, 2021, 44(6): 1440-1449.