Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm melanotan ii hmoov cas 121062-08-6 nyob Suav teb. Txais tos rau cov lag luam wholesale bulk zoo melanotan ii hmoov cas 121062-08-6 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Melanotan II hmoov(MT-2) yog lub chaw kuaj mob- ua tshuaj zoo ib yam li cov tshuaj hormones hauv tib neeg lub cev. Melanotan peptide tau raug pov thawj tias muaj melanin ntau lawm (tanning) thiab yang- ntxiv dag zog rau tib neeg. Melanotan, CAS 121062-08-6, yog cov hmoov dawb peptide. Kuj hu ua - Melanocyte stimulating hormone (-MSH) yog endogenous peptide nrog muaj zog melanocyte stimulating hormone ua haujlwm. Nws khi rau melanocyte stimulating hormone receptor subtype MC1R thiab activates melanocytes los tsim melanin nyob rau hauv ib txwm physiological mob los ntawm kev tswj ntawm lub hypothalamic pituitary adrenal axis. Nws yuav muaj cov khoom kho qhov muag tshwj xeeb, xws li fluorescence thiab absorbance. Cov khoom no yuav muaj feem xyuam nrog cov qauv thiab cov amino acid sib lawv liag ntawm peptides. Nws yog ib qho khoom siv hluavtaws peptide hormone uas simulates cov txheej txheem tswj ntawm daim tawv nqaij pigments hauv tib neeg lub cev. Lub hom phiaj tseem ceeb yog tswj thiab sib sib zog nqus pigmentation ntawm daim tawv nqaij, uas ua rau ib tug tob brownish xim.
Peb muab ib qho piv txwv ua lag luam ntawm no:
1. Hais lus
Nthuav cov ntaub ntawv khoom thiab Quantity.
2.Kev txiav txim thiab kev them nyiaj
Lub tuam txhab: Hloov txhab nyiaj rau txhua yam txiaj ntsig.
Tus neeg yuav khoom: Bitcion, USDT, Western Union
3.Packages, Shipping thiab lus
|
|
|
Rau cov neeg yuav khoom, cov tshuaj rhiab heev!
Shipping txheej txheem:
(1) 4-8 hnub
Peb tau tsim ib lub tuam txhab hauv koj cheeb tsam, uas yog tus neeg yuav khoom.
Ob lub tuam txhab muaj cov ntaub ntawv tiav thiab kev lag luam kom dhau los ntawm kev lis kev cai, tsis muaj kev pheej hmoo.
Kev xa khoom rau kev lag luam yog nruab nrab ntawm ob lub tuam txhab no, tsis muaj dab tsi ua rau koj.
(2) 0-2 hnub
Tom qab kev lis kev cai clearance, tuaj tos cov khoom los ntawm lub warehouse los yog xa lawv rau koj.
Tsis muaj ntaub ntawv yuav khoom, tsis kos npe, lub tsev khaws khoom yuav xa khoom rau koj!
4.OEM thiab ODM kev koom tes
Tshiab peptide R & D, tshiab specifications, pob thiab cov ntawv sau customization.
Lwm yam teeb meem ntawm OEM thiab tshwj xeeb specifications, thov hu rau peb kev muag khoom.
Tshaj tawm:
Tsis ntev los no, ntau lub tuam txhab tsis ua raws cai, pab pawg thiab txawm tias cov tib neeg tau ua txuj ua peb lub tuam txhab thiab luam tawm cov ntaub ntawv muag khoom cuav hauv Is Taws Nem, dag cov neeg siv khoom txawv teb chaws nrog cov nqi tsis tsim nyog. Thov paub meej tias lub npe sau npe ntawm koj lub vev xaib yog qhov tseeb thiab peb cov npe lag luam tau raug.
thov paub meej tias lub cim lag luam ntawm "BLOOM TECH".
|
Customized Bottle Caps Thiab Corks
|
|
Cov khoom nyob rau hauv tib series:
|
|
|
Melanotan II COA
Daim tawv nqaij Tanning thiab tiv thaiv
Nws yog feem ntau paub txog nws lub peev xwm los txhawb kev tsim melanin hauv daim tawv nqaij. Melanin yog cov xim uas muab cov xim ntawm cov tawv nqaij thiab tseem ua raws li cov tshuaj pleev thaiv hnub ntuj, tiv thaiv daim tawv nqaij los ntawm kev phom sij ntawm ultraviolet (UV) hluav taws xob. Los ntawm kev txhawb nqa tanning, Melanotan II tuaj yeem pab cov tib neeg ua tiav cov tawv nqaij tawv dua thaum muaj peev xwm txo tau txoj kev pheej hmoo ntawm mob qog noj ntshav. Txawm li cas los xij, nws tseem ceeb heev uas yuav tsum nco ntsoov tias kev siv Melanotan II rau lub hom phiaj no muaj teeb meem thiab tsis pom zoo rau tib neeg siv hauv ntau lub teb chaws vim muaj kev txhawj xeeb txog kev nyab xeeb.
Muaj peev xwm kho tau daim ntawv thov
Txawm hais tias tam sim no nws tsis tau pom zoo rau kev siv kho mob, kev tshawb fawb qhia tias nws yuav muaj txiaj ntsig kho mob hauv qee yam mob. Piv txwv li, qee qhov kev tshawb fawb tau tshawb xyuas nws cov peev xwm siv hauv kev kho mob ntawm kev sib deev, tshwj xeeb hauv cov txiv neej nrog erectile kawg. Melanotan II tau pom tias yuav siv tshuaj ntau npaum li cas - nyob ntawm qhov ua rau muaj kev cuam tshuam ntawm erections los ntawm kev ua rau cov xwm txheej erectile thiab txo lub sij hawm latency rau thawj qhov kev tshwm sim erectile. Txawm li cas los xij, cov kev tshawb pom no tseem yog qhov ua ntej, thiab xav tau kev tshawb fawb ntxiv kom paub meej tias kev nyab xeeb thiab kev ua tau zoo ntawm Melanotan II rau lub hom phiaj no.
Kev sim siv
Hauv qhov chaw sim, nws kuj tau kawm txog nws cov txiaj ntsig neuroprotective thiab neuroregenerative teebmeem. Piv txwv li, nws tau pom tias yuav txhawb kev tsim cov paj hlwb peripheral thiab txhim kho kev ua haujlwm zoo tom qab cov paj hlwb raug mob hauv cov qauv tsiaj. Tsis tas li ntawd, Melanotan II tau tshawb xyuas txog nws lub peev xwm los txo cov khoom noj thiab lub cev hnyav, nrog rau nws cov teebmeem ntawm thermogenesis hauv nas. Cov kev sim tshawb pom no qhia tias Melanotan II tuaj yeem muaj peev xwm siv tau rau kev kho mob rog rog thiab cuam tshuam txog cov kab mob metabolic, tab sis cov kev siv no tseem tab tom tshawb nrhiav.
Nws yog ib qho tseem ceeb uas yuav tsum tau hais txog tias kev siv Melanotan II rau ib qho ntawm cov ntsiab lus saum toj no - tau hais yog tam sim no sim thiab tsis pom zoo rau tib neeg siv. Kev nyab xeeb thiab kev ua tau zoo ntawm qhov sib xyaw no tsis tau raug soj ntsuam tag nrho hauv kev sim tshuaj, thiab nws qhov ntev - cov teebmeem tsis paub. Yog li ntawd, nws tau hais tawm tsam kev siv Melanotan II yam tsis muaj kev saib xyuas thiab kev pom zoo.
Hauv kev xaus, Melanotan II yog peptide cov tshuaj hormones nrog ntau yam physiological teebmeem uas tam sim no raug soj ntsuam rau cov kev siv tshuaj kho mob. Txawm li cas los xij, vim muaj kev txhawj xeeb txog kev nyab xeeb thiab tsis muaj kev pom zoo los ntawm kev kho mob, nws tsis pom zoo siv rau txhua lub hom phiaj kho mob rau lub sijhawm no.
Lub synthesis ntawmntshiab melanotansiv cov tshuaj synthesis yuav tsum muaj cov txheej txheem tshuaj tiv thaiv kab mob thiab cov pab pawg tiv thaiv tsim nyog los tiv thaiv cov amino thiab carboxyl pawg ntawm cov amino acids. Cov hauv qab no yog ib kauj ruam ua synthesis thiab tshuaj sib npaug:
Amino acid pretreatment:Kho cov amino acids xav tau nrog alkali tshem tawm cov pab pawg tiv thaiv thiab tau txais cov amino acids nrog cov amino pawg dawb.
Cov tshuaj tiv thaiv condensation:Dissolve cov amino acids kho nyob rau hauv cov organic hnyav (xws li DMF), ntxiv ib tug condensation tus neeg sawv cev (xws li DIC) thiab ib tug catalyst (xws li HOBt), thiab do nyob rau hauv chav tsev kub rau ob peb teev rau hnub kom tiav cov condensation cov tshuaj tiv thaiv. Cov tshuaj tiv thaiv no yuav tsum muaj kev tiv thaiv nitrogen los tiv thaiv kev cuam tshuam ntawm dej oxidation.
Kev tiv thaiv kev tiv thaiv:Tom qab cov tshuaj tiv thaiv condensation tiav, ntxiv deprotection reagents (xws li TFA) thiab do hauv chav sov li ob peb teev rau hnub kom ua tiav cov tshuaj tiv thaiv deprotection. Cov tshuaj tiv thaiv no kuj xav tau kev tiv thaiv nitrogen.
Ntxuav cov tshuaj tiv thaiv:Tom qab cov tshuaj tiv thaiv deprotection tiav lawm, ntxiv ib qho dej thiab cov kuab tshuaj organic (xws li DMF), do kom sib npaug, cia nws sawv ntsug rau txheej txheej, pov tseg cov txheej dej, thiab ntxuav ntau zaus kom tshem tawm cov residual deprotection reagents thiab lwm yam impurities.
Cyclization cov tshuaj tiv thaiv:Dissolve cov khoom ntxuav nyob rau hauv cov organic hnyav (xws li DMF), ntxiv ib tug cyclizing tus neeg saib xyuas (xws li CDI), thiab do nyob rau hauv chav tsev kub rau ob peb teev rau hnub kom tiav cov cyclization cov tshuaj tiv thaiv. Cov tshuaj tiv thaiv no kuj xav tau kev tiv thaiv nitrogen.
Purification tshuaj tiv thaiv:Tom qab cov tshuaj tiv thaiv cyclization tiav, kem chromatography yog ua kom tau purified Melanotan. Cov kauj ruam tshwj xeeb suav nrog kev ziab cov tshuaj tiv thaiv thiab dissolving hauv qhov tsim nyog ntawm cov kuab tshuaj organic (xws li ether), ntxiv cov nyiaj tsim nyog ntawm silica gel, sib tov sib npaug, thiab ua cov kem chromatography sib cais. Thaum cov eluent ntws los ntawm kem, cov khoom sib txawv yuav ntws tawm ntawm qhov sib txawv ntawm qhov sib txawv, thiab txhua yam yuav raug sau rau kev ntsuam xyuas thiab kev soj ntsuam purity.
Txias- ziab:Dissolve lub purified Melanotan nyob rau hauv ib tug tsim nyog tus nqi ntawm cov organic solvent (xws li ether), ntxiv ib tug tsim nyog tus nqi ntawm glycine, sib tov zoo, thiab ua freeze- qhuav kev kho mob. Thaum lub sijhawm khov- txheej txheem ziab, dej yuav raug tshem tawm ntawm cov tshuaj, ua rau cov khoom Melanotan qhuav.
Hauv qab no yog qee qhov sib npaug tshuaj rau kev sib txuasMelanotan Ii hmoovsiv chemical synthesis method:
R1-NH2+R2-COOH → R1-NH-CO-R2
R3 tiv thaiv pawg → R3-H
R4-H+R5-COOH → R4-CO-R5
R6-NH2+R7-COOH → R6-NH-CO-R7
R8-NH2+R9-COOH → R8-NH-CO-R9
Ntawm lawv, R1, R2, R3, R4, R5, R6, R7, R8, thiab R9 sawv cev rau pawg amino acid sib txawv, feem; Pawg tiv thaiv sawv cev rau pab pawg tiv thaiv. Cov kev sib npaug tshuaj saum toj no tsuas yog cov duab kos duab xwb, thiab cov txheej txheem synthesis tiag tiag yuav txawv nyob ntawm cov haujlwm tshwj xeeb thiab kev sim.
Nyob rau hauv xaus, lub synthesis ntawmmelanotan peptidesiv cov tshuaj synthesis yuav tsum tau muaj ntau yam tshuaj tiv thaiv thiab purification cov kauj ruam, thiab cov tshuaj tiv thaiv kab mob thiab cov txheej txheem kev khiav hauj lwm ntawm txhua kauj ruam yuav tsum tau nruj me ntsis tswj kom lub purity thiab tawm los ntawm cov khoom kawg. Nyob rau tib lub sijhawm, nws yuav tsum tau ua tib zoo saib xyuas kev siv cov tshuaj tiv thaiv kev nyab xeeb thiab ib puag ncig tus phooj ywg thiab cov kuab tshuaj, thiab ua raws li cov cai tswj kev nyab xeeb.
Kev phiv tshuaj
Cov tawv nqaij tiv thaiv
Cov tshuaj tiv thaiv ntawm daim tawv nqaij yog qhov tshwm sim tsis zoo tshaj plaws, feem ntau suav nrog cov hauv qab no:
Ntau pigmentation: Melanotan peptide txhawb kev tsim melanin, uas tuaj yeem ua rau tawv nqaij ntau dhau, pigmentation tsis sib xws lossis freckles.
Neoplastic nevi: Nws tau tshaj tawm tias cov neeg mob tuaj yeem tsim atypical melanocytic naevi tom qab siv Melanotan peptide, uas yuav ua rau muaj kev pheej hmoo ntawm kev hloov pauv tsis zoo.
Hauv qhov chaw melanoma: Hauv qee kis, kev siv Melanotan peptide tuaj yeem cuam tshuam nrog qhov tshwm sim ntawm melanoma hauv situ.
Kev ua xua ntawm daim tawv nqaij: Qee cov neeg mob yuav muaj kev tsis haum ntawm daim tawv nqaij xws li khaus, erythema, pob liab liab, thiab lwm yam.
Cardiovascular system teb
Melanotan peptide tuaj yeem muaj kev cuam tshuam tsis zoo rau cov hlab plawv, suav nrog cov hauv qab no:
Cov ntshav siab siab: Melanotan peptide tuaj yeem ua rau lub paj hlwb ua kom lub siab, ua rau muaj ntshav siab ntxiv.
Ua kom lub plawv dhia: Qee tus neeg mob yuav muaj kev nce siab hauv lub plawv, tshwj xeeb tshaj yog tom qab txhaj tshuaj.
Kev tshem tawm ntawm lub ntsej muag: Melanotan peptide tuaj yeem ua rau lub ntsej muag ntws tawm, uas cuam tshuam nrog kev nce ntshav siab thiab nce lub plawv dhia.
Digestive system teb
Kev xeev siab: xeev siab yog qhov feem ntau ntawm kev zom zaub mov tsis zoo ntawm Melanotan peptide, feem ntau tshwm sim hauv cov xuab moos tom qab txhaj tshuaj thiab kav ntev li ob peb teev mus rau hnub.
Txo qab los noj mov: Txawm hais tias Melanotan peptide muaj qhov ua kom qab los noj mov, qee cov neeg mob yuav muaj kev qab los noj mov, ua rau poob phaus.
ntuav: Qee tus neeg mob yuav ntuav ntuav, tshwj xeeb tshaj yog thaum cov koob tshuaj ntau dhau lossis qhov txhaj tshuaj nrawm dhau.
Mob plab: Qee tus neeg mob yuav mob raws plab, uas tej zaum yuav muaj feem xyuam rau cov nyhuv stimulating ntawm Melanotan peptide ntawm txoj hnyuv.
Neurological teb
Mob taub hau: Mob taub hau yog ib qho kev tsis zoo ntawm lub paj hlwb ntawm Melanotan peptide, feem ntau me me mus rau nruab nrab thiab kav ntev li ob peb teev mus rau hnub.
kiv taub hau: Qee cov neeg mob yuav muaj kiv taub hau, tshwj xeeb tshaj yog sai tom qab txhaj tshuaj.
Kev qaug zog: Qee tus neeg mob me me tuaj yeem ua rau qaug zog, uas tuaj yeem cuam tshuam nrog cov nyhuv inhibitory ntawm Melanotan peptide ntawm lub hauv paus paj hlwb.
Kev xav hloov pauv: Qee tus neeg mob yuav muaj kev hloov pauv ntawm kev xav xws li kev ntxhov siab, kev nyuaj siab, thiab lwm yam.
Kev pheej hmoo
koob tshuaj thiab kev kho mob ntev
Qhov koob tshuaj ntau dua thiab ntev npaum li cas ntawm kev kho mob ntev dua, qhov tshwm sim ntawm qhov tsis zoo tshwm sim ntau dua. Pom zoo pib los ntawm 0.25mg / hnub, nrog rau txhua lub limtiam increments tsis pub tshaj 0.25mg, thiab qhov siab tshaj plaws koob tshuaj tsis pub tshaj 1mg / hnub.
Cov khoom purity thiab qhov chaw
Cov khoom lag luam tsis raug cai yuav muaj cov khoom tsis huv lossis cov tshuaj tsis raug, ua rau muaj kev pheej hmoo ntawm kev ua xua thiab kis kab mob. Kev npaj tau pom zoo los ntawm FDA lossis EMA yuav tsum raug xaiv.
Qhov txawv ntawm tus kheej
gene polymorphism (xws li MC1 receptor rhiab heev) thiab cov kab mob yooj yim (xws li kub siab thiab ntshav qab zib) tuaj yeem cuam tshuam rau hom thiab qhov hnyav ntawm cov kev phiv tshwm sim.
Cim npe nrov: Melanotan ii hmoov CAS 121062-08-6, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom