4, 5-Dichloro-2-octyl-isothiazolone (DCOIT) (txuas:https://www.bloomtechz.com/synthetic-chemical/organic-intermediates/4-5-dichloro-2-octyl-isothiazolone-cas-164359.html), raws li cov kab mob bactericidal thiab antiseptic, muaj kev thov dav dav. Txawm li cas los xij, nrog kev xav tau ntau ntxiv rau kev ua phooj ywg ib puag ncig thiab kev nyab xeeb, DCOIT ntsib qee qhov kev sib tw.
Los ntawm lig 1960s mus rau thaum ntxov 1970s, DCOIT yog thawj zaug synthesized thiab dav siv nyob rau hauv lub teb ntawm industrial antifungal thiab antibacterial agents. Thaum lub sijhawm no, tib neeg tau pib ua tib zoo saib xyuas cov pa phem thiab kev puas tsuaj ntawm cov kab mob mus rau cov khoom lag luam, cov khoom siv thiab cov khoom siv. Txawm li cas los xij, qee cov tshuaj tua kab mob thiab tshuaj tua kab mob uas siv ua ntej muaj teeb meem toxicity thiab kev cuam tshuam ib puag ncig, thiab kev nyab xeeb thiab siv tau zoo dua yog qhov xav tau sai.
Nyob rau hauv cov ntsiab lus no, chemists pib tshawb fawb thiab tsim tshiab antifungal thiab antibacterial agents. Xyoo 1968, cov kws tshawb fawb los ntawm Stepan Tuam Txhab tau tsim cov thawj derivative ntawm DCOIT thiab pom tias nws muaj txiaj ntsig zoo hauv inhibiting kev loj hlob ntawm fungi thiab kab mob. Qhov kev ua tiav tau ua rau muaj kev txaus siab rau kev lag luam thoob plaws thiab tau dhau los ua tus neeg sawv cev nrov antimicrobial.
Los ntawm lig 1970s mus rau thaum ntxov 1980s, DCOIT pib dav siv nyob rau hauv lub teb ntawm coatings, textiles thiab ntoo preservation. Nws yog lub sijhawm no uas DCOIT tau nthuav dav rau ntau tus neeg siv khoom thiab cov khoom lag luam ua cov tshuaj tua kab mob zoo heev thiab tshuaj tua kab mob.
Txawm li cas los xij, nrog rau kev mloog zoo rau ib puag ncig ecological thiab tib neeg kev noj qab haus huv, kev tshawb fawb ntawm DCOIT tau dhau los ua ntau qhov tob. Cov kws tshawb fawb tau teeb tsa los ntsuas DCOIT ntawm biodegradability, toxicity, thiab ib puag ncig cuam tshuam. Cov kev tshawb pom pom tau hais tias txawm tias DCOIT muaj txiaj ntsig zoo ntawm cov kab mob thawj zaug thiab tshuaj tua kab mob, nws kuj muaj qee qhov kev pheej hmoo ntawm ib puag ncig thiab kev noj qab haus huv.
Txhawm rau txo qhov cuam tshuam tsis zoo rau ib puag ncig thiab txhim kho kev nyab xeeb kev ua haujlwm ntawm DCOIT, cov kws tshawb fawb tshuaj tau ua ntau yam kev tshawb fawb thiab tshawb fawb txog kev hloov pauv ntawm ib puag ncig thiab muaj txiaj ntsig zoo los ntawm kev txhim kho cov txheej txheem synthesis thiab optimizing cov qauv molecular. Cov kws tshawb fawb tau ua tiav ntau yam tshiab DCOIT derivatives thiab ntsuas lawv ntau.
Tsis tas li ntawd, cov kev cai lij choj thiab cov qauv thoob ntiaj teb tau maj mam txhim kho, tswj thiab txwv kev siv DCOIT hauv ntau qhov chaw. Qhov no ua rau cov tuam txhab lag luam thiab cov neeg siv them nyiaj ntau dua rau kev ua phooj ywg ib puag ncig thiab kev nyab xeeb ntawm DCOIT, thiab txhawb kev txhim kho nruj dua thiab siv cov qauv.
Sij hawm dhau mus, DCOIT tseem siv dav ua cov tshuaj tua kab mob thiab tshuaj tua kab mob, tab sis nws yuav tsum ua raws li cov cai thiab cov lus qhia cuam tshuam thaum siv nws. Nyob rau tib lub sijhawm, nrog kev nce qib ntawm kev tshawb fawb thiab thev naus laus zis tsis tu ncua thiab kev txhim kho ntawm ib puag ncig kev paub, qhov kev thov rau ntau tus phooj ywg ib puag ncig thiab kev nyab xeeb yog nce ntxiv, uas tseem txhawb kev tshawb fawb ntxiv thiab kev tsim kho tshiab thiab kev tsim kho tshiab.
Txhawm rau ua kom tiav, 4,5-Dichloro-2-octyl-isothiazolone (DCOIT), raws li cov organic compound, yog thawj zaug synthesized nyob rau hauv lig 1960s thiab thaum ntxov 1970s thiab nyiam kev lag luam. Nrog rau kev siv zog ntawm cov kws tshawb fawb, DCOIT tau maj mam siv rau thaj chaw ntawm txheej txheej, textiles, thiab ntoo khaws cia. Txawm li cas los xij, nrog kev txhawj xeeb txog kev cuam tshuam ib puag ncig thiab kev noj qab haus huv, DCOIT kev tshawb fawb tseem tob zuj zus, thiab nrhiav lwm txoj hauv kev zoo thiab nyab xeeb dua. Tsis tas li ntawd, cov kev cai thiab cov qauv tsim tau tsim rau kev siv DCOIT thoob ntiaj teb los tswj nws txoj kev siv. Nyob rau hauv lub neej yav tom ntej, nrog rau kev nce qib ntawm kev tshawb fawb thiab thev naus laus zis, peb muaj laj thawj ntseeg tias ntau yam kev nyab xeeb thiab kev nyab xeeb yuav tshwm sim.
Txoj kev loj hlob zeem muag ntawm DCOIT, thiab tshawb nrhiav cov lus qhia kev txhim kho.
1. Kev txhim kho ntawm lwm txoj kev:
Nrog rau kev ntxiv dag zog rau ib puag ncig cov cai thiab tib neeg kev txhawj xeeb txog kev phooj ywg ib puag ncig, kev siv DCOIT tau txwv. Yog li ntawd, nrhiav kev zoo ib puag ncig thiab kev nyab xeeb dua lwm txoj hauv kev yog ib qho ntawm cov lus qhia kev txhim kho yav tom ntej. Cov kws tshawb fawb tab tom tsim cov tshuaj tshiab thiab cov tswv yim los hloov lossis txhim kho DCOIT. Cov kev xaiv no yuav tsis tshua muaj tshuaj lom thiab zoo biodegradable, txo cov kev cuam tshuam rau ib puag ncig.
2. Kev txhim kho ntawm tus neeg tiv thaiv ntsuab:
Nrog rau qhov nrov ntawm lub tswv yim ntawm kev txhim kho kom ruaj khov, tus neeg saib xyuas ntsuab tau maj mam dhau los ua tus qauv ntawm kev lag luam. Cov tshuaj tiv thaiv ntsuab hais txog cov tshuaj lom neeg ib puag ncig, tsis muaj tshuaj lom, biodegradable, thiab muaj kev tiv thaiv zoo. Txhawm rau ua kom tau raws li kev xav tau ntawm kev lag luam, cov kws tshawb fawb tau mob siab rau lawv tus kheej los tsim cov tshuaj tiv thaiv ntsuab los hloov cov tshuaj organic hluavtaws xws li DCOIT. Cov tshuaj tiv thaiv ntsuab no tuaj yeem ua raws li cov khoom siv ntuj tsim, cov khoom siv roj ntsha lossis cov txheej txheem tsim khoom ib puag ncig kom ua tau raws li cov kev xav tau ntawm kev txhim kho kom ruaj khov.
3. Kev txhim kho thiab kev nthuav dav ntawm daim ntawv thov:
Ntxiv rau kev nrhiav lwm txoj hauv kev, kev ua haujlwm thiab kev ruaj ntseg ntawm DCOIT kuj tuaj yeem txhim kho los ntawm kev txhim kho thiab kev nthuav dav ntawm daim ntawv thov. Piv txwv li, txhim kho txoj kev npaj ntawm DCOIT kom txo tau cov khoom los ntawm cov khoom thiab kev siv hluav taws xob; Kev hloov kho cov qauv los txhim kho kev ruaj ntseg, kev ua haujlwm lom neeg thiab solubility ntawm DCOIT; txhim kho daim ntawv thov tshiab, xws li kev kho mob, kev ua zaub mov, thiab lwm yam. Cov kev txhim kho thiab kev txuas ntxiv no tuaj yeem ua rau DCOIT ua lub luag haujlwm hauv ntau thaj chaw thiab txo cov kev pheej hmoo rau ib puag ncig thiab tib neeg lub cev.
4. Kev tsim cov kev cai thiab cov qauv:
Nrog rau kev saib xyuas tas li rau kev nyab xeeb tshuaj, cov kev cai thiab cov qauv yuav raug txhim kho thiab ntxiv dag zog. Cov kev cai thiab cov qauv no yuav coj kev txhim kho thiab siv DCOIT thiab nws cov kev xaiv los xyuas kom meej lawv txoj kev nyab xeeb ntawm ib puag ncig thiab tib neeg kev noj qab haus huv. Kev tsim cov kev cai thiab cov qauv tsim nyog yuav pab txhawb kev txhim kho kev noj qab haus huv ntawm DCOIT thiab nws cov kev hloov pauv thiab tswj kev ua lag luam.
Nws yuav tsum tau muab sau tseg tias, raws li ib tug zoo bactericidal thiab preservative, DCOIT tseem muaj broad daim ntawv thov kev cia siab nyob rau hauv tej thaj chaw. Piv txwv li, kev lag luam xws li kev tsim kho, coatings, textiles thiab ntoo kho tej zaum yuav tseem xav tau cov tshuaj xws li DCOIT los tiv thaiv cov khoom los ntawm microbial paug thiab puas. Yog li ntawd, thaum siv DCOIT, yam xws li nws cov txiaj ntsig, nqi, kev pheej hmoo thiab kev ruaj khov yuav tsum raug txiav txim siab.
Hauv cov ntsiab lus, txoj kev loj hlob ntawm DCOIT suav nrog kev nrhiav lwm txoj hauv kev, tsim cov tshuaj tiv thaiv ntsuab, txhim kho thev naus laus zis thiab nthuav dav daim ntawv thov, thiab tsim cov kev cai thiab cov qauv. Los ntawm cov kev siv zog no, peb tuaj yeem ua tau raws li qhov xav tau ntawm ib puag ncig kev phooj ywg thiab kev nyab xeeb, thiab ua tiav lub hom phiaj ntawm kev txhim kho kom ruaj khov.