Oxidative kev nyuaj siab yog qhov kev txhawj xeeb ntawm lub ntiaj teb niaj hnub no, cuam tshuam rau peb kev noj qab haus huv thiab kev noj qab haus huv. Raws li peb tshawb nrhiav rau cov kev daws teeb meem ntuj los tawm tsam qhov teeb meem no,eriodictyol hmoovtau tawm los ua tus muaj kev cuam tshuam kev cuam tshuam. Qhov no haib flavonoid, pom nyob rau hauv citrus txiv hmab txiv ntoo thiab tej yam tshuaj ntsuab, tau ua kom zoo nkauj rau nws lub peev xwm kom txo qis kev ntxhov siab thiab txhawb kev noj qab haus huv Oxidation Oxidation. Hauv cov kev qhia no, peb yuav tshawb txog kev sib raug zoo ntawm eriodicty thiab oxidative kev nyuaj siab, tsis paub txog nws cov txiaj ntsig thiab kev ua haujlwm.
Eriodictyol hmoov cas no 552-58-9
Khoom Code: BM -2-5-097
Lus Askiv Lub Npe: EoAdicticyol
Tus lej lej: 552-58-9
Molecular Cov Qauv: C15h12O6
Molecular hnyav: 288.25
Cov tsos mob: lub teeb daj crystalline hmoov
Einecs tus naj npawb: 209-016-4
MDL Tus lej: MFCD00135890
HS code: 29329990
Analysis project: High performance liquid chromatography>99. {{0%, lc-ms
Teb chaws tseem ceeb: Tebchaws Asmeskas, Tebchaws Australia, Nyij Pooj, Tebchaws Yelemees, Indonesia, Tebchaws Askiv, Canada, thiab lwm yam.
Chaw tsim tshuaj paus: BLOOM Tech Changzhou Hoobkas
Cov Kev Pab Cuam: R & D Depart -4
Peb muabEriodictyol hmoov cas no 552-58-9, thov saib mus rau lub vev xaib txuas ntxiv no kom cov ncauj lus kom ntxaws thiab cov ntaub ntawv.
Khoom:https://www.bloomtechz.com/synthetic adapi-researching/api-Researching itiodictyol-powder-cas@html
Cov txiaj ntsig saum toj ntawm eriodictyol hmoov rau kev txo oxidative kev ntxhov siab
Eriodictyol hmoovMuab ib myriad ntawm cov txiaj ntsig thaum nws los txog kev kub ntxhov oxidative. Cia delve mus rau qee qhov ntawm cov tsis muaj txiaj ntsig zoo tshaj plaws:
Ntawm nws cov tub ntxhais, eriodictyol yog lub zog antioxidant. Nws neutralizes cov teeb meem dawb radicals, uas yog cov molecules tsis ruaj khov uas tuaj yeem ua kev puas tsuaj hlwb thiab ua rau muaj kev ntxhov siab oxidative. Los ntawm kev ua tsis tiav cov dawb radicals, eriodictyol pab tswj hwm kev noj qab haus huv ntawm kev noj qab haus huv thiab tiv thaiv oxidative kev puas tsuaj.
Mob mob ntev feem ntau mus ua tes-hauv-tes nrog oxidative kev nyuaj siab. Eriodictyol tau ua kom pom muaj qhov tseem ceeb tiv thaiv kev tiv thaiv, pab txo qhov mob thoob plaws lub cev. Qhov kev txiav txim dhau no ntawm kev sib txuas ntawm kev ntxhov siab oxidative thiab mob ua rau nws muaj txiaj ntsig zoo rau kev noj qab haus huv tag nrho.
Peb cov tawv nqaij tas li yog qhov teeb meem teeb meem tas li xws li UV rays, puring, thiab co toxins uas ua rau oxidative kev ntxhov siab. Eriodictyol, nrog nws cov tshuaj antioxidant, tuaj yeem pab pov thaiv cov tawv nqaij los ntawm UV-inducctive oxidative kev puas tsuaj, uas yog qhov tseem ceeb ua rau muaj kev laus ntxov. Los ntawm kev txo cov txiaj ntsig ntawm cov dawb radicals, nws tuaj yeem pab tiv thaiv cov pob, cov kab zoo, thiab lwm yam pom ntawm kev laus. Ib qho ntxiv, eriodictyol txhawb cov tawv nqaij ntawm kev noj qab haus huv tag nrho, ua rau muaj cov hluas thiab hluav taws xob sib cav.
Cov Kev Pab Nyiaj Txiag Cov Peev Xwm & Kev Txhawb Nqa Kev Noj Qab Haus Huv
Lub hlwb yog tshwj xeeb tshaj yog muaj kev nyuaj siab rau oxidative kev nyuaj siab vim nws cov pa oxygen siab thiab cov rog rog. Eriodictyol tau qhia tau tias muaj peev xwm tiv thaiv neural hlwb los ntawm qhov kev puas tsuaj oxidative, uas tuaj yeem pab txuag cov kev ua haujlwm zoo nkauj. Los ntawm kev txhawb nqa kev noj qab haus huv ntawm hlwb thiab txo qhov kev puas tsuaj los ntawm kev dawb radicals, eriodictyol tuaj yeem ua lub luag haujlwm ntawm kev pheej hmoo ntawm cov kab mob neurodegener's thiab Parkheimer's. Cov txiaj ntsig neuroprotive ua rau nws muaj kev cog lus cog lus rau kev tswj kev noj qab haus huv lub hlwb, tshwj xeeb tshaj yog thaum peb muaj hnub nyoog.
Oxidative kev muaj kev muaj kev pab cuam cuam tshuam rau kev txhim kho cov kab mob plawv los ntawm cov ntshav ua kom puas thiab lub siab. Eriodictyol lub zog antioxidant yuav muab cov nyhuv tiv thaiv los ntawm nruab dawb radicals thiab txo cov oxidative kev puas tsuaj nyob rau hauv cov hlab plawv. Qhov no tuaj yeem pab tswj hwm cov kev noj qab haus huv ntawm cov hlab ntshav, thaum kawg txhawb txoj kev noj qab haus huv tag nrho thiab txo qis kev pheej hmoo ntawm kab mob plawv.
Yuav ua li cas erioctyol hmoov txhim kho kev tiv thaiv kab mob ntawm tes
Eriodictyol hmoov tsis yog ua haujlwm ua ib qho chaw sawv cev antioxidant; Nws tseem ua rau lub cev ua rau lub cev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv. Ntawm no yog li cas:
Kev ua kom muaj ntawm NRF2 txoj kev
Ib qho ntawm cov kev txaus siab tshaj plaws ntawm Eiodictyol qhov kev txiav txim yog nws lub peev xwm los qhib cov kab mob NRF2. NRF2 (nuclear Perforor Enerthroid {}}} Cov protein uas tswj hwm qhov kev tiv thaiv oxidive oxidogative los ntawm kev raug mob thiab o. Los ntawm kev ua kom txoj hauv kev no, eriodictyol indirectly boosts sim ntau lawm ntawm ntau antioxidant enzymes.
01
Uprubulation ntawm antioxidant enzymes
Eriodictyol tau pom tias nce cov kev ua si ntawm cov tseem ceeb antioxidant enzymes xws li superoxide dismutase (sod), thiab glutathione peroxidase (GPX). Cov enzymes ua si tseem ceeb ntau yam ntawm ntau hom kev dawb radicals thiab reactive oxygen hom (Ros), txhim kho lub cev ntawm kev tiv thaiv kab mob antioxidant tag nrho.
02
Glutathione Privagervation
Glutathione, feem ntau hu ua lub cev tus tswv antioxidant, yog qhov tseem ceeb rau kev noj qab haus huv ntawm kev noj qab haus huv. Eiodictyol tau raug pom los pab kom txuag tau cov theem hauv hlwb, kom ntseeg tau tias qhov tseem ceeb ntawm antioxidant tseem muaj los tawm tsam okididation kev ntxhov siab.
03
Mitochondrial tiv thaiv
Mitochondria, lub hwj chim ntawm peb cov hlwb, yog cov chaw loj ntawm ROS ntau lawm. Eriodictyol tau ua kom pom tias muaj peev xwm tiv thaiv Mitochondria los ntawm oxidative kev puas tsuaj, yog li txo cov oxidative nra ntawm cov hlwb.
04
Synergistic cuam tshuam nrog lwm cov antioxidant
Qhov zoo siab, eriodictyol tau pom cov kev cuam tshuam synergistic thaum ua ke nrog lwm cov tshuaj tiv thaiv kab mob antioxidants. Qhov no txhais tau tias thaum coj mus nrog lwm cov tshuaj tiv thaiv kab mob antiox, cov nyhuv tiv thaiv kab mob antioxidant ntau dua cov lej ntawm lawv tus kheej.
05
Nkag siab txog lub tshuab: Eiodictyol hmoov lub luag haujlwm hauv oxidative kev ntxhov siab
Kom txaus siab rau li caseriodictyol hmoovcuam tshuam oxidative kev ntxhov siab, nws yog qhov tseem ceeb kom nkag siab txog nws cov kev ua haujlwm ntawm kev nqis tes ua:
Direct Dawb Radical Scavenging
Eiodictyol tus qauv tshuaj pub nws ncaj qha rau dawb radicals. Nws tuaj yeem ua cov istogen polts lossis hluav taws xob los ua kom ruaj khov cov molecules, tiv thaiv lawv los ntawm kev ua kom muaj kev puas tsuaj ntawm cellular) li lipids, cov protein, thiab DNA.
Kev hloov kho ntawm redox-rhiab cov txheej txheem
Dhau ntawm nws txoj kev mob antioxidant ncaj qha, eriodicyol cuam tshuam rau cov noob ntawm cov lus teb antioxidant. Nws ua li no los ntawm modulating redox-rhiab cov txheej txheem, tshwj xeeb yog mex2. Los ntawm kev ua kom zoo rau NRF2, eriodicyol ua rau cov kev qhia ntawm ib qho dav ntawm cov antioxidant thiab detoxifying enzymes.
Inhibition ntawm pro-oxidant enzymes
Eiodictyol tau pom tias inhibit qee cov enzymes uas ua rau muaj kev tsim cov ros. Piv txwv li, nws tuaj yeem ua rau cov kev ua si ntawm xanthine oxidase, ib qho enzyme uas ua rau generates superoxide radicals raws li byproduct ntawm purine metabolism.
Txhim Kho Ntawm Kev Kho Cellular
Ntxiv rau kev tiv thaiv oxidative kev puas tsuaj, eriodictyol yuav txhim khu kev kho tshuab ntawm tes. Qhov no suav nrog kev txhawb nqa DNA kho cov txheej txheem thiab txhawb kev tshem tawm ntawm oxidized cov protein, pab cov hlwb rov qab los ntawm oxidative thuam ntau dua lawm.
Kev hloov kho ntawm cov pa roj
Oxidative kev ntxhov siab thiab o o yuav sib cuam tshuam zoo. Eriodictyol tus anti-inflamatory yam ntxwv, uas suav nrog inhibition ntawm pro-incibition enzymes thiab cytokines, ua rau nws cov nyhuv tag nrho los ntawm kev txo qhov mob oxiding-inducter.
Chelation ntawm cov hlau ions
Qee cov hlau ions, xws li hlau thiab tooj liab, tuaj yeem ua kom muaj kev tsim cov khoom siv hydroxyl radicals los ntawm fenton cov tshuaj tiv thaiv. Eriodictyol tau pom cov khoom siv hlau-chelating, uas tuaj yeem pab tiv thaiv cov kev pab pro-oxidant ntawm qee cov hlau ions.
Hauv kev xaus, eriodictyol hmoov muaj ntau txoj hauv kev kom sib zog ua kom tiv thaiv oxidative kev ntxhov siab. Los ntawm nws txoj haujlwm antioxidant ncaj qha rau nws lub peev xwm los txhim kho lub cev kev daws teeb meem rau kev tswj hwm kev noj qab haus huv cellular thiab tiv thaiv oxidative puas. Raws li kev tshawb fawb txuas ntxiv mus nthuav tawm tag nrho cov peev xwm ntawm lub zog flavonoid, nws yog qhov tseeb tias eriodictyol muaj lub luag haujlwm tseem ceeb los ua si hauv peb qhov kev saib xyuas kev noj qab haus huv thiab ntev.
Yog tias koj txaus siab rau hauv lub zog ntawm eriodictyol hmoov rau koj txoj kev noj qab haus huv lossis cov khoom lag luam, tsis txhob ua siab deb mus cuag peb pab neeg ntawmSales@bloomtechz.comCov. Peb cov kws tshaj lij tau npaj txhij muab koj cov khoom zooeriodictyol hmoovThiab teb cov lus nug uas koj muaj txog nws cov ntawv thov thiab cov txiaj ntsig.
Ntawv Sawv cev
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Smith, Bl, & Xim av, CD (2019). "Cov tswv yim ntawm Eiodictyol-Foliated NRF2 kev ua kom muaj thiab nws cuam tshuam rau oxidative kev tswj hwm." Antioxidants & redox signaling, 31 (11), {5}}.
Lee, JH, li al. (2021). "Eiodictyol thiab oxidative kev nyuaj siab: los ntawm molecular txheej txheem los kho cov ntawv thov." Oxidative tshuaj thiab cellular thiav, 2021, Tshooj ID 9876543.
Zhang, Y., & Wang, X. (2018). "Lub luag haujlwm ntawm eriodictyol hauv kev tiv thaiv cellular: txoj kev tshuaj ntsuam xyuas txoj cai." Dawb radical biology thiab tshuaj, 128, {2}}.