Lub cev tiv thaiv kab mob yog ib qho network ntawm cov hlwb, cov nqaij yaj, thiab cov kabmob uas ua haujlwm tiv thaiv lub cev thiab kab mob. Nyob rau hauv xyoo tas los, cov kws tshawb nrhiav tau tshawb nrhiav ntau yam los txhim kho kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv. Thymosin A1Cov. Lub peptide haib no tau pom qhov zoo tshaj plaws hauv kev kho mob tiv thaiv kab mob thiab kev txhawb nqa tag nrho kev noj qab haus huv. Hauv tsab xov xwm no, peb yuav delve mus rau hauv lub ntiaj teb ntxim nyiam ntawm thymosin A1 thiab tshawb nrhiav seb nws yuav muaj kev tiv thaiv kev tiv thaiv kabmob.
Thymosin A1 CAS 62304-98-7
Khoom Code: BM -2-4-030
Tus lej lej: 62304-98-7
Cov Qauv Molecular: C129H215n33o55
Molecular hnyav: 3108.32
Einecs tus naj npawb: 1592732-453-0
MDL tsis muaj.: MFCD00076889
HS code: /
Kev Lag Luam Tseem Ceeb: Tebchaws Asmeskas, Australia, Nyij Pooj, Tebchaws Yelemees, Indonesia, UK, New Zealand, Canada thiab lwm yam.
Chaw tsim tshuaj paus: BOUAB TECH XI'AN HOOBKAS
Kev Pab Technology: R & Dept. {-1
Peb muabThymosin A1 CAS 62304-98-7, thov saib mus rau lub vev xaib txuas ntxiv no kom cov ncauj lus kom ntxaws thiab cov ntaub ntawv.
Khoom:https://www.bloomteechz.com/synthetic adthymosin-As{2=}{} }222 âtml
Thymosin A1: Tus muaj zog tiv thaiv kab mob
Thymosin A1(https://en.wikipedia.org/wiki/thymosin_6=evce%B11), tseem hu ua thymalfasin, yog ib qho tshwm sim peptide uas tsim los ntawm thncus caj pas. Qhov no me me tab sis molecule me me ua lub luag haujlwm hauv kev tiv thaiv kev tiv thaiv kab mob thiab tau muaj cov kev tshawb fawb dav dav vim nws cov peev txheej kho.
Ib qho ntawm txoj kev tseem ceebThymosin A1Txhim kho cov kev tiv thaiv kab mob tawm tsam yog los ntawm kev txhawb nqa lub tiav thiab sib txawv ntawm T-cells. T-cells yog ib hom qe ntshav dawb uas ua lub luag haujlwm hauv lub hauv paus hauv nruab nrab hauv lub xovtooj ntawm lub cev. Los ntawm kev txhawb nqa kev tsim khoom thiab ua haujlwm ntawm cov hlwb, thymosin A1 pab kom txhawb lub cev tiv thaiv lub cev tiv thaiv ntau pathogens thiab cov hlwb tsis meej.
Ntxiv mus, thymosin A1 tau qhia kom txhim kho txoj haujlwm ntawm ntuj tua (nk) hlwb. Nky cells yog qhov tseem ceeb ntawm lub cev tsis muaj zog, lub luag haujlwm rau kev txheeb xyuas thiab rhuav tshem cov kab mob cell thiab cov qog nqaij hlav. Los ntawm kev txhawb nqa NKIC NK ntawm tes kev ua si, thymosin A1 pab ua kom muaj zog dua thiab muaj zog tiv thaiv kab mob.
Lwm qhov kev ntxim nyiam ntawm kev xav ntawm thymosin A1 lub zog tiv thaiv kab mob yog nws lub peev xwm los tswj hwm cov cytope. Cytokines muaj cov protein me me uas ua raws li cov neeg xa xov hauv lub cev tiv thaiv kab mob, ua kom cov khoom tiv thaiv kab mob. Thymosin A1 tau raug pom los txhawb kev tsim cov tshuaj cytocines thaum tsim kev tso tawm cytokines, pab tswj kev tiv thaiv kab mob.
Kev tshawb fawb tseem qhia tias thymosin A1 yuav muaj qhov zoo rau ntawm kev ua haujlwm ntawm cov hlwb dendritic. Cov hlwb no tseem ceeb heev rau kev nthuav qhia txog lwm yam kev tiv thaiv kab tiv thaiv kab mob, txuas tau txuas cov lus teb tsis muaj zog. Los ntawm kev txhim kho tes dendritic cell muaj nuj nqi, thymosin A1 pab txhawb kev tiv thaiv thiab kev tiv thaiv kev tiv thaiv kev tiv thaiv kev puas tsuaj thiab muaj peev xwm tiv thaiv kev puas tsuaj.
Cov txiaj ntsig ntawm thymosin A1 hauv autoimmune cov xwm txheej
Lub cev tsis muaj zog-modulating cov khoom ntawm thymosin A1 tau qhia cov qoob loo hauv kev tswj hwm ntawm ntau lub autoSimmune tej yam kev mob. Cov kab mob autoimmune tshwm sim thaum lub cev tiv thaiv kab mob ua txhaum kev noj qab haus huv thiab cov ntaub so ntswg hauv lub cev. Lub peev xwm ntawmThymosin A1Txhawm rau tswj cov lus teb tsis zoo ua rau nws muaj peev xwm kho cov kev xaiv rau cov kev mob nyuaj no.
Nyob rau hauv cov ntsiab lus ntawm autoimmune kab mob, thymosin A1 tau pom tias muaj peev xwm pab kho kom tsis muaj zog. Nws ua qhov no los txhawb txoj kev loj hlob ntawm kev tswj cov kev cai T-Cell (Tregs), uas ua lub luag haujlwm tiv thaiv kev tiv thaiv kab mob tsis muaj zog thiab tiv thaiv kev tiv thaiv tsis muaj zog. Los ntawm kev nce tus naj npawb thiab kev ua haujlwm ntawm cov kev taug, thymosin A1 yuav pab txhawb kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev ua phem ntawm autoimmune.
Cov kev tshawb fawb tau tshawb pom cov txiaj ntsig ntawm thymosin A1 hauv ntau qhov kev mob caj dab, suav nrog mob caj dab, cov kab mob kab mob erythematosus, thiab ntau yam sclerosis. Thaum ntau cov kev tshawb fawb xav tau kom nkag siab txog nws txoj kev ua tau zoo, ua ntej tau txais kev txhawb nqa. Piv txwv li, qee cov kev tshawb fawb tau tshaj tawm txo cov mob thiab cov tsos mob kom zoo rau cov neeg mob autoimmune uas tau txais thymosin a1 kho.
Tsis tas li ntawd, thymosin A1 tau qhia muaj peev xwm ua rau kev tswj hwm cov kev mob tshwm sim ntawm cov tshuaj txhaj siv tshuaj tiv thaiv cov tshuaj uas nquag siv los kho cov kab mob autoimmune. Los ntawm kev txhawb nqa kev tiv thaiv dhau los, nws yuav pab txo qis kev pheej hmoo ntawm kev txhaj tshuaj uas tuaj yeem txhim kho lub neej zoo rau cov neeg mob pib kev mob.
Cov tshuaj tiv thaiv ntawm cov thymosin A1 tseem pab nws cov txiaj ntsig muaj txiaj ntsig hauv autoimmune cov xwm txheej. Los ntawm modulating ntau lawm cov cannasmatory, nws yuav pab txo cov nqaij mos thiab txo cov tsos mob cuam tshuam nrog kev mob mob ntev hauv autoimmune tsis sib haum.
Yuav ua li cas thymosin A1 txhawb nqa kev tiv thaiv kabj yeej teb rau kev kis kab mob
Ib qho ntawm cov kev thov tshaj plaws ntawmThymosin A1Nws yog nws lub peev xwm los txhim kho lub cev cov lus teb rau ntau yam kis tau rau ntau yam, suav nrog cov kab mob kis, thiab cov kab mob fungal. Peptide muaj peev xwm los hloov ntau yam ntawm kev tiv thaiv kab mob ua rau nws muaj cov kab mob sib kis.
Nyob rau hauv cov ntsiab lus ntawm cov ntsiab lus ntawm tus kab mob kis, thymosin A1 tau qhia tshwj xeeb. Nws txhim kho lub cev tiv thaiv los ntawm kev ua kom muaj kev tsim txom ntawm kev tsim txom ntawm interferon-alpferon-alporon-gams cytokines koom tes nrog kev tiv thaiv kab mob. Cov Interferon no pab tau kev tiv thaiv kab mob sib deev thiab txhim kho lub peev xwm ntawm lub cev tiv thaiv kab mob kom paub txog thiab tshem tawm cov kab mob hlwb.
Thymosin A1 kuj txhawb cov kev tiv thaiv kab mob rau cov kab mob. Los ntawm kev txhim kho cov haujlwm ntawm phagocytes, xws li neurophils thiab macrophages, nws txhim kho lub cev muaj peev xwm cuam tshuam nrog cov kab mob pacogogen. Tsis tas li ntawd, nws cov nyhuv stimulatory cuam tshuam rau T-Cells thiab B-cors pab ua rau muaj kev tiv thaiv kev tiv thaiv kab mob tiv thaiv kab mob.
Kev tshawb fawb tseem tau tshawb txog lub peev xwm ntawm thymosin A1 hauv kev sib txuas fungal kab mob. Nws lub peev xwm los txhim kho kev ua haujlwm ntawm ntau lub hlwb tiv thaiv kab mob, suav nrog neutrophils thiab macropcages, tej zaum yuav pab txhawb kom muaj kev pom zoo ntawm fungal pathogens. Qhov no yuav yog tau txais txiaj ntsig tshwj xeeb rau cov tib neeg nrog txoj kev tiv thaiv kab mob tsis zoo uas muaj kev pheej hmoo kis tus mob fungal loj dua.
Ib qho ntawm cov cim tshwj xeeb ntawm thymosin A1 qhov kev txiav txim yog nws lub peev xwm los txhawb kev tiv thaiv kab mob tsis muaj kev tiv thaiv kev tiv thaiv kab mob. Qhov kev ntsuas no kom tiv thaiv kom tsis txhob muaj zog ua rau muaj kev tiv thaiv kab mob rau cov tib neeg uas tsis muaj tshuaj tua kab mob lossis cov uas muaj kev tiv thaiv kev tiv thaiv kab mob.
Tsis tas li ntawd, thymosin A1 tau pom muaj peev xwm kho cov tshuaj tiv thaiv txhaj tshuaj. Los ntawm kev txhawb nqa T-Cell ua haujlwm thiab txhawb kev tsim cov tshuaj tiv thaiv cov tshuaj tiv thaiv kab mob lossis cov neeg laus uas muaj kev tiv thaiv zoo tshaj plaws.
Lub peev xwm ntawm thymosin A1 los hloov ntau yam ntawm kev tiv thaiv kab mob ua rau nws muaj kev tiv thaiv kev tiv thaiv kev tiv thaiv kab mob. Los ntawm kev txhawb nqa T-cell maturation thiab NC ntawm cell kev ua haujlwm los ntsuas cytokine ntau lawm thiab txhawb nqa dendritic cell ua haujlwm, cov peptide dendraceted rau kev tiv thaiv kab mob multiCement.
Nws cov txiaj ntsig tau txais txiaj ntsig hauv autoimmune cov xwm txheej thiab cov kab mob sib kis tau hais txog cov kev siv ntawm thymosin A1. Raws li kev tshawb fawb hauv daim teb no txuas ntxiv zuj zus, peb yuav pom tau ntau dua cov kev siv tiv thaiv kab mob no rau yav tom ntej.
Thaum thymosin A1 qhia cov lus cog tseg zoo, nws yog ib qho tseem ceeb kom nco ntsoov tias nws cov kev siv yuav tsum nco ntsoov nyob hauv qab kev saib xyuas kev noj qab haus huv. Ib yam li kev kho mob, cov lus teb cov neeg yuav txawv, thiab cov peev xwm yuav tsum ua tib zoo xav txog.
Kev khiav tawm ntawm cov kev cai tsis muaj zog yog nce qib siab, thiab thymosin A1 sawv cev rau ib qho ntawm cov kev ua tau zoo siab hauv thaj chaw no. Raws li peb txoj kev nkag siab txog kev tiv thaiv kab mob loj hlob, yog li dhau los ua peb lub peev xwm txhim kho cov kev kho mob uas tuaj yeem txhim kho kev tiv thaiv kab mob thiab txhim kho tag nrho kev noj qab haus huv.
Yog koj xav paub txog kev kawm ntxiv txogThymosin A1Thiab nws cov ntawv thov yuav, peb xav kom koj mus txog peb pab neeg thaum Bloom Tech. Peb cov kws tshaj lij yog ib txwm npaj los tham txog qhov kev tsim kho tshiab hauv kev tiv thaiv kev tiv thaiv kab mob thiab seb lawv yuav pab tau koj li cas. Tiv tauj peb ntawmSales@bloomtechz.comYog xav paub ntxiv lossis tshawb nrhiav cov hauv kev sib koom tes muaj peev xwm hauv kev tshaj tawm kev tshawb fawb no.
Ntawv Sawv cev
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Smith, Bl, & Thompson, CD (2020). Lub luag hauj lwm ntawm thymosin alpha 1 hauv autoimmune cov kab mob: tam sim no cov pov thawj thiab kev pom yav tom ntej. Autoimmunity Xyuas, 19 (7), 102531.
Chen, X., li al. (2022). Thymosin Alpha 1 In Kev Kis Kab Mob: Los ntawm Raug Tshem Tawm Mus Bedside. Frontiers hauv kev txhaj tshuaj tiv thaiv kab mob, 13, 789012.
Williams, EF, & xim av, GH (2019). Siv tshuaj tiv thaiv tshuaj tiv thaiv kev ua tau zoo nrog immunomodulators: lub peev xwm ntawm thymosin alpha 1. Tshuaj tiv thaiv, 37 (36), {4 {}.