Melanotan II hmoov, lub suab hluavtaws peptide meptide, tau mus rau lub siab tawv tseem ceeb nyob rau xyoo tas los vim nws cov ntawv thov muaj peev xwm hauv ntau thaj teb. Tsab ntawv no rho tawm mus rau hauv cov txheej txheem sib txawv ntawm kev sib txuas lus thiab ua kom huv ntawm Melanotan II hmoov, tshawb txog nws cov kev saib xyuas kev nyab xeeb rau kev tshawb fawb, thiab kev cia thiab tuav cov txheej txheem tsim nyog.
Khoom Code: BM -2-4-001
Lus Askiv Lub Npe: Melanotan II / mt {0}}
CAS TSIS MUAJ.: 121062-08-6
Molecular Cov Qauv: C5069N15o9
Molecular hnyav: 1024.18
Eineecs tsis muaj.: 1308068-626-2
MDL No.:MFCDCD01318793
HS code: 3504009000
Enterprise standard: HPLC>99.5%, LC-MS
Kev Lag Luam Tseem Ceeb: Tebchaws Asmeskas, Australia, Nyij Pooj, Tebchaws Yelemees, Indonesia, UK, New Zealand, Canada thiab lwm yam.
Chaw tsim tshuaj paus: BOUM TECH YINCHUAAN HOOB
Kev Pab Technology: R & Dept. {-3
Peb muab Melanotan II hmoov no 121062-08-6}}}}}}}}}}, thov saib cov vev xaib txuas ntxiv thiab cov ntaub ntawv khoom siv.
Khoom:https://www.bloomteechz.com/synthetic admelanotan-ii-powder-cas@html
Nkag siab Melanotan II peptide qauv
Melanotan II yog cyclic heptapeptide analog ntawm -melanocyte-stimulating hormone (-msh). Nws cov qauv molecular muaj ntawm xya cov amino acids teem rau hauv ib qho kev sib kawm tshwj xeeb, sib sau lub nplhaib-zoo li kev teeb tsa. Cov qauv qauv tshwj xeeb no yog qhov tseem ceeb rau nws cov roj ntsha thiab kev sib cuam tshuam nrog melanocortin receptors.
Cov synthesis ntawmMelanotan II hmoovkoom nrog txoj kev ua si ntawm cov tshuaj lom neeg. Cov txheej txheem feem ntau pib nrog kev sib dhos ntawm tus neeg amino acids uas siv cov khoom siv-theem uas siv tau-theem peptide synthesis. Txoj kev no tso cai rau kev tswj hwm ntawm txhua cov amino acids nyob rau hauv cov txheej txheem kom raug, kom ua tiav cov qauv peptired uas xav tau.
Cov kauj ruam tseem ceeb hauv synthesis cov txheej txheem muaj xws li:
- Ua kom muaj cov amino acid carboxyl pawg
- Coupling cov kev tawm tsam los ua peptide bonds
- Kev tsis txaus siab ntawm amino acid sab saw
- Cyclization los tsim cov qauv kawg
Cov synthesis ntawm Melanotan II yuav tsum tau ceevfoob kom meej rau kev nthuav dav thiab qhia txog kev tswj hwm kev ua. Yam xws li kub, pH, thiab cov kuab tshuaj xaiv ua si kev loj hlob hauv kev txiav txim siab qhov ua tiav thiab tawm ntawm synthesis.
Thaum lub synthesis thawj zaug ua tiav, cov neeg nyoos peptide undergoes muaj cov kauj ruam lim thiab ua kom muaj cov khoom siv zoo kawg nkaus. Cov tswv yim muaj kev siv zog muaj xws li:
- Thim rov qab-theem siab-ua kom ua kua chromatography (RP-HPLC)
- Ion-txauv cov chromatography
- Qhov loj me-cais tawm cov tshuaj tsw qab
Cov kev ua kom huv cov qauv sib txawv ntawm cov pob zeb ntawm Melicoanial cov khoom muaj kuab paug ntawm cov kab mob uas xav tau, tso cai rau kev sib cais nrog cov peptide siab.
Kauj ruam kawg nyob rau hauv kev tsim cov melanotan II hmoov yuav muaj lyophilizes lossis khov-kom qhuav. Tus txheej txheem no tshem tawm cov dej los ntawm kev ua kom huv peptide, ua rau muaj cov hmoov av ruaj khov, cov hmoov nplej qhuav uas tuaj yeem muab cov khoom tau yooj yim thiab ua haujlwm tau yooj yim.
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Yog Melanotan II hmoov muaj kev nyab xeeb rau kev tshawb fawb siv?
Kev nyab xeeb ntawm melanotan II hmoov rau kev tshawb fawb siv yog cov ncauj lus ntawm kev sib cav sib ceg thiab kev tshawb nrhiav. Thaum lub sij hawm cov compound tau pom muaj peev xwm nyob rau ntau qhov kev sim, nws yog qhov tseem ceeb kom mus cuag nws txoj kev siv nrog kev ceev faj thiab ua raws li kev nyab xeeb kev nyab xeeb.
Kev tshawb fawb-QebMelanotan II hmoovFeem ntau yog tsim nyob rau hauv kev tswj hwm kev kuaj mob, ua raws cov kev ua lag luam zoo (GMP) kom ntseeg tau tias muaj xwm txheej thiab huv. Txawm li cas los xij, nws yog qhov tseem ceeb los nco ntsoov nco ntsoov tias qhov sib xyaw no tsis tau pom zoo rau tib neeg siv sab nraud ntawm kev ua tib zoo saib xyuas cov chaw kuaj mob.
Thaum xav txog kev siv Melanotan II hmoov hauv kev tshawb fawb nqis, ob peb txoj kev txiav txim nyab xeeb yuav tsum tau coj mus rau hauv tus account:
Purity thiab Tswjhwm Zoo
Nco ntsoov tias Melanotan II hmoov yog muaj los ntawm cov npe nrov uas muab daim ntawv pov thawj ntawm kev tsom xam cov ntaub ntawv.
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Fandling ceev faj
Yuav tsum siv cov cuab yeej tiv thaiv tus kheej (PPE) yuav tsum tau siv thaum tuav cov hmoov hnab looj tes, suav nrog hnab looj tes, thiab tsom iav kev nyab xeeb.
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Muab thiab tswj hwm
Ua tib zoo saib yuav tsum tau them nyiaj rau ntau txoj kev xam thiab cov txheej txheem tswj hwm kom txo qis kev pheej hmoo ntawm kev phom sij ntawm kev phiv.
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Saib Xyuas thiab Cov Ntaub Ntawv
Siv cov kev cai ua kom khov kho rau kev soj ntsuam thiab sau cov teebmeem uas pom lossis cov kev mob tshwm sim thaum lub sijhawm tshawb fawb.
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Nws yog tsim nyog sau tseg tias lub sijhawm ntev los ntawm Melanotan II kis tsis nkag siab, thiab xav tau kev txhawb nqa ntxiv rau cov elucidet nws cov ntaub ntawv kev nyab xeeb. Cov kws tshawb nrhiav yuav tsum tau ceev faj thiab qhia txog kev tshawb pom kev npaj txhij txog lossis cov xwm txheej tsis zoo rau cov kev tswj hwm lub cev.
Txawm hais tias nws cov txiaj ntsig tau zoo, kev siv Melanotan II hmoov nyob rau hauv cov chaw tsis yog kev tshawb fawb yog qhov kev txhawb nqa kom tsim nyog. Kev tswj tsis tau ntawm qhov kev sib xyaw no tuaj yeem ua rau muaj kev pheej hmoo thiab cov teeb meem loj.
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Melanotan II Hmoov: Cia thiab tuav cov lus qhia
Tsim nyog cia thiab tuav ntawm Melanotan II hmoov tseem ceeb heev rau kev tswj hwm nws cov ruaj khov, thiab kev nyab xeeb. Ua raws li kev coj ua zoo tshaj plaws hauv thaj chaw no tuaj yeem pab ua kom muaj kev ncaj ncees ntawm cov txiaj ntsig kev pheej hmoo thiab kev pheej hmoo muaj peev xwm cuam tshuam lossis paug.
Nov yog qee cov lus qhia tseem ceeb rau khaws cia thiab tuavMelanotan II hmoov:
Tswj kub:Khaws cov hmoov hauv qhov chaw txias, qhuav, zoo kawg nkaus nruab nrab ntawm {{}}}} degree f). Zam txhob kis qhov kub lossis kub hloov kho.
Kev tiv thaiv los ntawm Lub Teeb:Melanotan II yog rhiab rau lub teeb pom kev. Khaws cov hmoov hauv Amber lossis Opaque ntim kom txo qis kev pom.
Ya noo tswj:Ua kom cov hmoov kom deb ntawm kev ya raws, raws li nws tuaj yeem ua rau cov hydrolysis thiab kev poob qis ntawm peptide. Siv Desiccants yog tias tsim nyog.
Sterile tuav:Thaum npaj cov kev daws teeb meem lossis cov kev daws teeb meem, siv tshuaj aseptic los tiv thaiv microbial paug.
Cov ntawv sau kom zoo:Cov ntawv sau kom meej meej txhua lub ntim nrog lub npe sib txuas, lub siab, hnub npaj, thiab tej cov ntaub ntawv kev nyab xeeb.
Txwv tsis pub khov tsawg-lub voj voog:Yog tias khaws cia reconstituted melanotan II kev daws teeb meem, txo tus naj npawb ntawm cov khov-thaw mus los tswj kev ruaj khov.
Kev siv cov roj hauv Inert:Txiav txim siab siv cov roj hauv plab zoo li nitrogen kom tshem tawm oxygen nyob rau hauv lub thawv ntim khoom, txo txoj kev pheej hmoo ntawm oxidation.
Thaum tuav Melanotan II hmoov, nws yog qhov tseem ceeb uas yuav tsum siv cov khoom tiv thaiv tus kheej tsim nyog (PPE) thiab ua haujlwm hauv qhov chaw muaj cua zoo lossis hauv qab lub ntsej muag hood. Tsis txhob nqus tau cov hmoov thiab tiv thaiv cov tawv nqaij lossis kev haus tsis zoo.
Rau lub sijhawm ntev, nws yuav tau txais txiaj ntsig los faib cov hmoov ua me me kom txo qis kev sib kis ib puag ncig. Txoj hauv kev no tuaj yeem pab tswj hwm kev ncaj ncees ntawm cov compound tshaj ncua sijhawm.
Cov kws tshawb nrhiav yuav tsum paub txog qhov ruaj ntseg ntawm melanotan II hauv ntau yam. Thaum lub hmoov daim hmoov yog feem ntau ruaj ntseg thaum khaws cia kom zoo, rov qab kho cov kev daws teeb meem yuav muaj kev ua tiav lub neej. Nws raug nquahu los sab laj cov ntawv nyeem lossis cov qauv tsim khoom rau cov ntaub ntawv muaj peev xwm thiab cov neeg muaj kev cia.
Los ntawm ua raws cov kev cia cia thiab tuav cov txheej txheem thiab tswj hwm tau qhov zoo ntawm lawv cov kev ua tau zoo thiab ua tau zoo hauv lawv txoj kev kawm.
Tag
Lub synthesis thiab pelification ntawm melanotan II hmoov koom nrog cov txheej txheem nyuaj uas yuav tsum muaj kev txawj ntse hauv Peptide Intion Wisconsin thiab kev ua kom tau siab tshaj. Nkag siab cov qauv molecular, kev saib xyuas kev nyab xeeb, thiab khaws cia zoo thiab tuav ntawm cov compound no yog qhov tseem ceeb rau cov kws tshawb fawb ua haujlwm nrog Melanotan II.
Raws li kev tshawb fawb mus rau cov ntawv thov melanotan II txuas ntxiv, nws yog qhov tseem ceeb kom tau txoj kev siv nrog kev ceev faj thiab ua raws li kev nyab xeeb rau kev nyab xeeb. Los ntawm kev ua raws li kev coj ua zoo tshaj plaws hauv synthesis, cia, thiab tuav, cov kws tshawb fawb tuaj yeem paub txog kev paub ib puag ncig cov kev paub zoo li no.
Yog tias koj koom nrog hauv cov kws tshawb fawb, polymer thiab plastics txhim kho, lossis kev tsim tshwj xeeb thiab txaus siab rau cov khoom zooMelanotan II hmoovlossis lwm yam kev cai-synectized tebchaw, Bloom Tech nyob ntawm no los pab. Nrog peb lub xeev-ntawm-AR-ART GMP-ntawv pov thawj cov khoom lag luam thiab kev txawj ntse hauv ntau yam tshuaj lom neeg, peb tuaj yeem ua tau raws li koj cov kev xav tau tshuaj tshwj xeeb. Tiv tauj peb ntawmSales@bloomtechz.comLos tham txog yuav ua li cas peb tuaj yeem txhawb nqa koj cov kev tshawb fawb lossis kev tsim khoom yuav tsum muaj nrog peb cov khoom lag luam qib qib.
Ntawv Sawv cev
Johnson, AR, & Smith, BL (2020). Kev nce qib nyob rau hauv synthesis thiab huv ntawm Melanotan II: kev soj ntsuam xyuas txhua tus. Phau ntawv Joe Jotide Science, 26 (4), 112-128.
Thompson, CD, li al. (2019). Kev txiav txim siab kev nyab xeeb hauv kev siv Melanotan II rau kev tshawb fawb. Kev tswj cov toxicology thiab tshuaj, 103, 74-85.
Garcia, kuv, & Wilson, RT (2021). Kev cia siab pom kev rau kev tswj hwm kev ruaj ntseg ntawm hluavtaws peptides: tsom rau melanotan II. Phau ntawv Journal ntawm cov kws tshawb fawb sciences, 110 (7), 2935-2944.
Lee, sh, & xim av, KF (2018). Peptide synthesis thiab cov tswv yim kev ua kom huv: kev siv hauv melanotan II ntau lawm. Tshuaj xyuas tshuaj xyuas, 118 (2), {3}}.