Methylene xiavfeem ntau yog siv los ua tshuaj tua kab mob thiab feem ntau yog siv los cawm cov tshuaj lom hauv tsev kho mob.
1. Nws yog ib qho oxidant uas nws qhov kev txiav txim muaj kev sib raug zoo nrog nws cov concentration. Ntawm qhov tsis tshua muaj siab, methylene xiav thiab dawb methylene xiav tuaj yeem hloov mus rau ib leeg dua. Cov txheej txheem hloov pauv kuj tseem nrog cov tshuaj tiv thaiv redox, uas tuaj yeem cuam tshuam cov lus teb ntawm methemoglobin los cawm cov tshuaj lom. Ntawm qhov siab siab, methylene xiav feem ntau ua lub luag haujlwm ntawm oxidation, uas tuaj yeem oxidize ib txwm hemoglobin rau hauv methemoglobin. Methemoglobin tuaj yeem ua ke nrog cyanide los cawm cyanide lom. Clinical methylene xiav tuaj yeem siv los khaws cov neeg mob uas muaj nitrite lom, lom aniline, tshuaj lom cyanide thiab lwm yam tshuaj lom. Thaum siv methylene xiav, them sai sai rau qhov sib thooj concentration.
2. tseem hu ua methylene xiav, nws yog tsuas yog siv rau cov neeg mob uas muaj nitrite lom. Nitrite lom kuj tseem hu ua entheogenic cyanosis. Vim yog cov nitrite noj los ntawm tib neeg lub cev, tib neeg lub cev methemoglobin yog oxidized rau methemoglobin, uas poob lub peev xwm los ua ke nrog oxygen, ua rau cov tsos mob hnyav ntawm hypoxia. Tus neeg mob pom cov tsos mob xws li cyanosis ntawm daim di ncauj, cyanosis ntawm ceg thiab hypoxia. Lub sijhawm no, nws tuaj yeem kho nrog methylene xiav. Vim tias methylene xiav tuaj yeem txo cov methemoglobin mus rau methemoglobin, rov ua kom muaj peev xwm ua ke nrog oxygen thiab rov ua kom cov pa oxygen ntawm tib neeg lub cev, lub luag haujlwm tseem ceeb ntawm methylene xiav yog los kho methemoglobinemia los ntawm ntau yam, tshwj xeeb tshaj yog methemoglobinemia tshwm sim los ntawm nitrite. Nyob rau tib lub sijhawm, methylene xiav piv tuaj yeem siv los kho cov tshuaj lom cyanide.
Qhov no yog ib qho oxidant feem ntau siv los kho methemoglobinemia los ntawm cov tshuaj lom neeg xws li nitrite thiab nitrate lossis tshuaj (acetaminophen thiab phenacetin). Nws toxicity tuaj yeem ncua ib ntus qhov tshwm sim ntawm mob cyanide lom. Txawm li cas los xij, nws yuav tsum raug sau tseg tias cov khoom no muaj txiaj ntsig zoo rau ferrihemoglobinemia tshwm sim los ntawm cov tshuaj xws li nitrite, nitrate, aniline, nitrobenzene, trinitrotoluene, benzoquinone, phenylhydrazine thiab cov tshuaj uas muaj lossis tsim cov tshuaj tsw qab (acetanilide, acetaminophen, phenacetin, thiab lwm yam). . Nws muaj kev cuam tshuam tsis zoo ntawm methemoglobinemia los ntawm qhov tsis muaj peev xwm ntawm cov pyridine diphosphate nucleoside methemoglobin reductase. Nws tsis zoo rau qhov txawv txav hemoglobin m nrog methemoglobinemia. Nws tuaj yeem ncua kev toxicity ntawm tus mob cyanide lom ib ntus.
Ntxiv nrog rau kev siv los ua tshuaj tua kab mob hauv tsev kho mob, methylene xiav kuj tuaj yeem siv rau lwm yam:
1. Methylene xiavtseem tuaj yeem siv rau kev kho mob analgesia, feem ntau hauv kev phais mob hemorrhoid. Donkey nkaum gelatin tuaj yeem ua rau cov paj hlwb xaus. Tom qab siv tshuaj, nws tuaj yeem ua ke los tsim cov nyhuv tuag tes tuag taw los txo qhov mob.
2. Kev kho cov zis calculi: methylene xiav tuaj yeem yaj lub zais zis pob zeb kom nws tuaj yeem siv rau cov zis calculi. Nws muaj txiaj ntsig zoo rau cov pob zeb calcium oxalate. Tsis txhob noj zaub mov muaj calcium ntau thaum lub sijhawm kho, haus dej ntau dua, thiab ua kom cov zis diluted.
3. Kho obliterative vasculitis.
4. Kev kho mob neurodermatitis: Cov khoom no muaj kev sib raug zoo nrog cov paj hlwb. Kev txhaj tshuaj hauv zos ntawm cov tshuaj tuaj yeem ua rau cov hlab ntsha xaus thiab ua rau cov hlab ntsha peripheral medulla. Lub medulla tshiab yuav raug kho tom qab li 30 hnub. Nyob rau hauv kev kho mob neurodermatitis, compound tov ntawmMethylene xiavtxhaj tshuaj hauv zos hauv ntau qhov chaw. Muaj mob ntau tom qab txhaj tshuaj. Tom qab li 4 teev, qhov mob maj mam hloov mus rau hauv loog loog. Nyob rau lub sijhawm no, cov hlab ntsha medulla puas lawm vim yog kev txhawb nqa ntawm cov hlab ntsha peripheral. Tom qab li ntawm 30 hnub, medulla tshiab hlob tuaj, thiab qhov kev xav tuaj yeem rov qab mus rau qhov qub. Qee qhov xwm txheej yuav rov zoo dua, tab sis qib ntawm daim tawv nqaij qhov mob tsawg dua li ua ntej.