Lub compound tetracaine hydrochloride mucilageplays lub luag haujlwm zoo hauv kev kho mob.
Gastroscopy yog ib txoj hauv kev zoo rau kev kuaj mob ntawm cov kab mob plab sab sauv. Txawm li cas los xij, vim muaj cov hnoos qeev hauv txoj hlab pas thiab lub plab, thiab tus neeg mob tsis xis nyob nqos cov hnoos qeev uas tau muab ntxiv rau lub sijhawm kuaj, qhov pom kev tsis meej, uas cuam tshuam rau kev soj ntsuam thiab kev ua haujlwm. Txhawm rau txhim kho qhov tseeb ntawm gastroscopy thiab txo cov kev txom nyem ntawm cov neeg mob, cov neeg ua haujlwm kho mob tau ua ntau yam kev tshawb fawb txog kev siv tshuaj loog hauv zos thiab tshuaj tua kab mob hauv gastroscopy. Nws tau raug pov thawj hauv kev kho mob tias ntau qhov kev npaj rau gastroscopy uas ua ke nrog cov tshuaj loog hauv zos thiab cov tshuaj tua kab mob yog qhov zoo dua li cov tshuaj loog hauv zos lossis cov tshuaj tua kab mob ib leeg. Cov koom haum cuam tshuam tau tsim cov khoom sib xyaw tetracaine hydrochloride mucilage uas ua ke nrog tshuaj loog hauv zos, defoaming, thiab lubrication. Lub mucous daim nyias nyias ntawm lub caj pas yog anesthetized sai sai, cov nyhuv yog tseeb, thiab cov kev phiv tshwm sim yog me me, tab sis qee cov neeg mob muaj tsis zoo defoaming kev ua tau zoo, uas cuam tshuam rau endoscopy. Pom tau. Txawm hais tias dimethicone nyob rau hauv nws cov formulation muaj preliminary defoaming zog, nws dispersing zog yog tsis zoo, thiab nws yuav tsum tau uniformly dispersed thiaj li yuav exert ib tug zoo defoaming nyhuv. Ua ke nrog kev kho mob, cov mis raug tshuaj xyuas nrog defoaming tus nqi raws li qhov Performance index, cov txheej txheem kev npaj ntawm compound tetracaine hydrochloride mucilage tau optimized, nws defoaming kev ua tau zoo dua, thiab nws kuj muab cov ntaub ntawv siv rau txoj kev loj hlob ntawm nws cov tshiab dosage daim ntawv.
1. Kev npaj ntawm compound tetracaine hydrochloride mucilage
Take sodium carboxymethyl cellulose, add an appropriate amount of hot purified water, swell naturally, leave it overnight to completely dissolve, add dimethicone, glycerin, and polysorbate 80, stir evenly, heat to about 80 degree , use high shear Mixing emulsifier for 10 min to complete the emulsification; add tetracaine hydrochloride and citric acid, add purified water to dissolve, combine with the above solution, and stir well; add ethylparaben dissolved in an appropriate amount of ethanol, add purified water to 100 ml, stir well, and that's it.
2. Kev txiav txim siab ntawm defoaming tus nqi
Cov khoom defoaming ntawm cov tshuaj tau txiav txim siab los ntawm txoj kev kawm tiav lub tog raj kheej. Nyob rau hauv cov xwm txheej ntawm chav tsev kub thiab lub siab ib txwm, coj 100 ml lub tog raj kheej kawm tiav, ntxiv 20 ml ntawm cov kua foaming (0.031 moL / L octyl benzene polyol aqueous tov), ntsaws lub tog raj kheej tiav nrog ib lub cork nrog lub qhov, thiab co nce thiab nqis (oscillation amplitude 30-40 cm, co tus nqi 50-70 zaug / min), ua npuas ncauj ntim ncav cuag 60 ml cim, ntxiv 0.2 ml ntawm cov tshuaj ntsuam xyuas (xws li defoamer. ) raws li lub raj phab ntsa nrog lub hau yas, thiab kaw tom qab 30 feeb. Ua npuas ncauj ntim (V). Qhov me me ntawm qhov seem ntawm cov npuas dej, qhov ntau dua qhov defoaming tus nqi, qhia tau hais tias defoaming kev ua tau zoo ntawm cov compound tetracaine hydrochloride mucilage zoo dua. Defoaming tus nqi (v, ml / min)=(60 - V) / 30.
Yog tias koj xav paub ntau ntxiv txog tetracaine hydrochloride thiab lwm yam ntawm peb lub tuam txhab thiab cov khoom, thov koj xav tiv tauj peb, peb zoo siab los pab koj.