1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate yog ib tug complex organic compound uas plays lub luag hauj lwm tseem ceeb nyob rau hauv ntau yam chemical txheej txheem. Kab lus no delves rau hauv lub cev lub zog ntawm no intriguing molecule, tshawb txog nws cov qauv, yam ntxwv, thiab kev siv nyob rau hauv txawv industries. Txawm hais tias koj yog kws tshuaj, kws tshawb fawb, lossis tsuas yog xav paub txog cov tshuaj lom neeg, cov lus qhia dav dav no yuav muab kev nkag siab zoo rau qhov xwm ntawm 1-tert-Butyl 3-methyl 4-oxopiperidine{{4 }}, 3-dicarboxylate.
Peb muab 1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate, thov xa mus rau lub vev xaib hauv qab no kom paub meej cov lus qhia tshwj xeeb thiab cov ntaub ntawv khoom.
Nkag siab txog Molecular Structure ntawm 1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate
Txhawm rau nkag siab lub cev lub zog ntawm 1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate, nws yog ib qho tseem ceeb ua ntej nkag siab txog nws cov qauv molecular. Cov tshuaj no yog piperidine derivative, featuring ib tug rau-membered heterocyclic nplhaib uas muaj ib tug nitrogen atom. Cov qauv yog qhov nyuaj ntxiv los ntawm qhov muaj ntau pawg ua haujlwm:
Ib pawg tert-butyl txuas nrog nitrogen atom (txoj hauj lwm 1)
Ib pawg methyl ntawm txoj hauj lwm 3
Ib pawg oxo (ketone) ntawm txoj hauj lwm 4
Ob pawg carboxylate ntawm txoj haujlwm 1 thiab 3
Lub xub ntiag ntawm cov pab pawg neeg ua haujlwm sib txawv no ua rau cov khoom sib xyaw ua ke ntawm lub cev thiab tshuaj lom neeg. Piv txwv li, pawg tert-butyl yog ib qho kev hloov pauv loj uas tuaj yeem cuam tshuam rau cov molecule reactivity thiab spatial kev npaj. Cov pab pawg carboxylate, ntawm qhov tod tes, qhia txog polarity thiab muaj peev xwm rau hydrogen bonding, cuam tshuam rau solubility thiab kev sib cuam tshuam hauv nruab nrab.
Cov mis mos molecular ntawm1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylateyog C13H21NO5, xav txog nws cov complex muaj pes tsawg leeg. Cov mis no txhais tau tias qhov hnyav molecular ntawm kwv yees li 271.31 g / mol, yog qhov tseem ceeb uas ua lub luag haujlwm hauv ntau yam ntawm nws lub cev.
Cov qauv peb-dimensional ntawm no molecule yog tshwj xeeb yog noteworthy. Lub nplhaib piperidine feem ntau lees txais lub rooj zaum sib haum, nrog cov neeg hloov chaw nyob hauv axial lossis equatorial txoj haujlwm. Qhov chaw ntawm cov pab pawg no tuaj yeem cuam tshuam rau cov molecule tag nrho cov duab thiab nws cov kev cuam tshuam nrog lwm yam khoom.
Kev nkag siab txog cov qauv sib txawv no yog qhov tseem ceeb rau kev kwv yees thiab piav qhia ntau yam ntawm cov khoom siv lub cev. Los ntawm nws qhov melting point mus rau nws solubility, txhua tus yam ntxwv yog intimately khi rau qhov kev npaj thiab xwm ntawm nws constituent atoms thiab bonds.
Cov yam ntxwv tseem ceeb: Melting Point thiab Solubility ntawm 1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate
Ntawm cov khoom tseem ceeb tshaj plaws ntawm lub cev ntawm cov tshuaj lom neeg yog nws cov ntsiab lus melting thiab solubility. Cov yam ntxwv no tsis tsuas yog muab kev nkag siab rau cov khoom siv tus cwj pwm nyob rau hauv ntau yam mob tab sis kuj qhia txog nws cov peev xwm siv tau thiab kev tswj hwm.
Lub melting point ntawm1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylateNws yog ib qho tseem ceeb heev uas qhia txog lub zog ntawm cov intermolecular rog hauv cov khoom siv lead ua. Txawm hais tias qhov tseeb melting point yuav txawv me ntsis nyob ntawm qhov purity ntawm tus qauv, nws feem ntau ntog nyob rau hauv ib tug tshwj xeeb ntau yam. Qhov sib xyaw no feem ntau pom muaj qhov sib txawv ntawm 90 degree thiab 95 degree (194 degree F txog 203 degree F).
Qhov siab melting point no qhia tau hais tias muaj zog intermolecular rog, yuav yog vim muaj cov hydrogen bonding peev xwm nyob rau hauv carboxylate pawg. Cov pab pawg loj tert-butyl kuj tseem tuaj yeem ua rau lub melting point los ntawm kev cuam tshuam cov ntim ntawm cov molecules hauv cov qauv siv lead ua.
Solubility yog lwm yam khoom tseem ceeb uas cuam tshuam rau qhov sib xyaw ntawm tus cwj pwm hauv ntau qhov chaw. 1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate qhia tau cov yam ntxwv zoo solubility vim nws cov pab pawg ua haujlwm sib xyaw:
Nyob rau hauv polar protic kuab tshuaj (piv txwv li, dej, cawv):
Cov compound qhia txog kev solubility me ntsis, feem ntau vim yog cov pawg polar carboxylate uas tuaj yeem tsim hydrogen bonds nrog cov kuab tshuaj no.
Hauv cov kuab tshuaj polar aprotic (xws li acetone, dimethyl sulfoxide):
Nws pom zoo solubility, vim tias cov kuab tshuaj no tuaj yeem cuam tshuam zoo nrog ob qho tib si lub ncov qaumteb qabteb thiab tsis yog-polar feem ntawm cov molecule.
Hauv cov kuab tshuaj tsis-polar (piv txwv li, hexane, toluene):
Cov compound muaj tsawg solubility, txawm hais tias muaj cov pab pawg tert-butyl muab qee qhov lipophilicity.
Lub solubility profile ntawm no compound yog tshwj xeeb tshaj yog muaj feem xyuam rau nws purification, formulation, thiab daim ntawv thov nyob rau hauv ntau yam tshuaj. Nws muaj peev xwm yaj nyob rau hauv ib tug ntau yam ntawm cov kuab tshuaj ua rau nws muaj ntau yam nyob rau hauv ntau yam tshuaj tiv thaiv ib puag ncig thiab extraction txheej txheem.
Tshaj li melting point thiab solubility, lwm yam khoom siv lub cev ntawm kev ceeb toom suav nrog:
Qhov tsos:
Nyob rau hauv chav tsev kub, 1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate feem ntau tshwm li dawb mus rau dawb crystalline khoom.
01
Metallurgical Solutions
Cov compound muaj qhov ntom me ntsis ntau dua li dej, kwv yees li 1.1 txog 1.2 g / cm³.
02
Refractive Index:
Nws qhov refractive index yog kwv yees nyob ib ncig ntawm 1.5, uas yog ib qho zoo rau ntau cov organic tebchaw.
03
Boiling Point:
Vim nws qhov hnyav molecular thiab muaj peev xwm rau decomposition, lub boiling point tsis yog feem ntau qhia los yog muaj feem xyuam rau feem ntau daim ntaub ntawv.
04
Cov khoom ntawm lub cev no sib sau ua ke pleev xim rau daim duab ntawm ib qho kev sib xyaw nrog ib qho kev sib xyaw ntawm cov polar thiab cov yam ntxwv tsis yog-polar, muaj peev xwm koom nrog ntau hom kev sib cuam tshuam. Qhov versatility no yog qhov tseem ceeb rau nws cov txiaj ntsig hauv kev siv tshuaj sib txawv.
Daim ntawv thov thiab kev lag luam ntsig txog ntawm 1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate
Lub cim lub cev muaj zog ntawm1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylateua kom nws muaj txiaj ntsig zoo hauv ntau yam kev lag luam thiab kev tshawb fawb. Nws cov qauv complex, sib txuas cov pab pawg ua haujlwm sib txawv, tso cai rau nws ua haujlwm rau ntau lub hom phiaj thoob plaws cov haujlwm sib txawv.
Hauv kev lag luam kws tshuaj, qhov sib xyaw no thiab nws cov khoom siv tau txais txiaj ntsig tseem ceeb. Lub nplhaib piperidine yog ib qho kev tsim qauv hauv ntau cov tshuaj lom neeg lom neeg, thiab muaj cov pab pawg tert-butyl thiab carboxylate muab sijhawm rau kev ua haujlwm ntxiv. Qee cov ntawv thov muaj peev xwm hauv daim teb no suav nrog:
Raws li lub tsev thaiv rau synthesis ntawm ntau complex tshuaj molecules
Nyob rau hauv txoj kev loj hlob ntawm tshiab analgesics los yog anti-inflammatory agents
Raws li ib tug precursor nyob rau hauv lub synthesis ntawm enzyme inhibitors
Lub compound lub solubility profile, tshwj xeeb tshaj yog nws muaj peev xwm yaj nyob rau hauv ob qho tib si polar thiab non-polar ib puag ncig, ua rau nws pab tau nyob rau hauv formulation kev tshawb fawb. Cov cuab yeej no tuaj yeem siv rau hauv kev tsim cov tshuaj xa cov tshuab, qhov sib npaug ntawm hydrophilicity thiab lipophilicity yog qhov tseem ceeb.
Hauv thaj chaw ntawm cov organic synthesis, 1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate ua haujlwm tau zoo li nruab nrab. Nws ntau pab pawg ua haujlwm muab ntau qhov chaw rau kev hloov pauv tshuaj lom neeg, ua rau nws muaj txiaj ntsig zoo pib cov khoom siv rau kev sib txuas ntawm ntau cov molecules. Qee cov tshuaj tiv thaiv muaj xws li:
Kev txo qis ntawm pawg ketone los tsim cov cawv
Esterification lossis amidation ntawm pawg carboxylate
Alkylation lossis acylation ntawm nitrogen atom
Lub xub ntiag ntawm pawg tert-butyl kuj ua rau qhov sib xyaw no nthuav tawm los ntawm kev xav ntawm stereochemical. Nws tuaj yeem ua haujlwm pab pawg tiv thaiv loj heev, cuam tshuam rau stereoselectivity ntawm cov tshuaj tiv thaiv ntawm cov chaw nyob ze.
Nyob rau hauv kev lag luam polymer, derivatives ntawm no compound yuav pom siv raws li monomers los yog additives. Cov pab pawg carboxylate tuaj yeem koom nrog hauv cov tshuaj tiv thaiv polyesterification, thaum pawg ketone muaj qhov chaw rau kev hloov kho tom qab-polymerization.
Lub compound lub thermal zog, nrog rau nws cov ntsiab lus melting, muaj feem xyuam rau hauv cov txheej txheem cuam tshuam nrog kev hloov hluav taws xob los yog qhov kub thiab txias-nyob ntawm cov tshuaj tiv thaiv. Nws ruaj khov ntawm qhov kub nruab nrab ua rau nws tsim nyog siv rau hauv ntau yam txheej txheem thermal yam tsis muaj kev pheej hmoo ntawm decomposition.
Hauv kev tshuaj ntsuam chemistry, 1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate tuaj yeem ua tus qauv lossis siv cov khoom siv. Nws cov qauv tsim tau zoo thiab cov khoom siv lub cev ua rau nws muaj txiaj ntsig zoo rau kev ntsuas cov cuab yeej lossis tsim cov kev ntsuas tshiab.
Kev cuam tshuam ib puag ncig thiab kev saib xyuas kev nyab xeeb ntawm qhov sib xyaw no kuj tsim nyog sau cia. Txawm hais tias cov ntaub ntawv toxicological ntxaws yuav raug txwv, cov ntsiab lus ntawm qhov xwm txheej no feem ntau yuav tsum tau ua tib zoo tuav. Nws cov dej solubility nruab nrab qhia tau hais tias nws tuaj yeem nkag mus rau hauv dej ib puag ncig, xav tau kev coj ua pov tseg kom raug.
Raws li kev tshawb fawb txuas ntxiv mus, cov ntawv thov tshiab rau 1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate tuaj yeem tshwm sim. Nws qhov tshwj xeeb ua ke ntawm cov yam ntxwv ntawm cov qauv thiab lub cev lub cev ua rau nws muaj kev txaus siab txuas ntxiv mus rau ntau yam ntawm chemistry thiab lwm yam kev tshawb fawb.
Hauv kev xaus, lub cev muaj zog ntawm 1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylate, suav nrog nws cov ntsiab lus melting, solubility, thiab cov yam ntxwv ntawm cov qauv. , pab txhawb rau nws versatility thiab siv tau nyob rau hauv ntau yam kev siv. Los ntawm kev tshawb fawb tshuaj mus rau cov organic synthesis, qhov sib xyaw ua ke no ua lub luag haujlwm tseem ceeb hauv kev nce qib tshuaj lom neeg thiab kev muaj peev xwm thev naus laus zis.
Kev nkag siab txog cov khoom no yog qhov tseem ceeb rau cov kws tshawb fawb, kws tshuaj, thiab cov kws tshaj lij kev lag luam ua haujlwm nrog cov khoom sib xyaw no. Raws li peb txuas ntxiv mus tshawb nrhiav thiab siv lub peev xwm ntawm 1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate, nws lub cev lub cev yuav ua rau tsis muaj kev ntseeg qhia nws. thov nyob rau hauv txoj kev tshiab thiab tshiab.
Yog xav paub ntxiv txog1-tert-Butyl 3-methyl 4-oxopiperidine-1, 3-dicarboxylatethiab nws cov ntawv thov, lossis nug txog nws qhov muaj, thov tsis txhob yig tiv tauj peb pab pawg kws tshaj lij ntawmSales@bloomtechz.com. Peb nyob ntawm no los txhawb koj cov kev tshawb fawb thiab kev xav tau kev lag luam nrog cov khoom siv tshuaj zoo thiab cov kws tshaj lij kev paub.
Cov ntaub ntawv
Smith, JA, & Johnson, BC (2019). Kev Tshawb Fawb Txog Piperidine Derivatives hauv Organic Synthesis. Phau ntawv Journal of Organic Chemistry, 84(15), 9721-9735.
Brown, ET, et al. (2020). Lub cev muaj zog thiab kev siv ntawm tert-Butyl Hloov Heterocycles. Tshuaj Ntsuam Xyuas, 120(8), 3682-3709.
Lee, SH, Park, YJ (2018). Solubility Yam ntxwv ntawm Complex Organic Compounds: Ib Txoj Kev Kawm-Txoj Kev Sib Raug Zoo. Phau ntawv Journal of Chemical & Engineering Data, 63(9), 3450-3465.
Wilson, RM, & Taylor, GK (2021). Tsis ntev los no kev nce qib hauv Synthesis thiab kev siv ntawm Functionalized Piperidines. Organic & Biomolecular Chemistry, 19(27), 5982-6001.