1-Naphthalene acetic acid,CAS C12H10O2 tus lej sau npe: 86-87-3, tshuaj npe: -naphthalene acetic acid, lub cev thiab tshuaj lom neeg: koob dawb siv lead ua los yog crystalline hmoov, tsw ntxhiab. Me ntsis soluble hauv dej txias thiab ethanol, yooj yim soluble hauv dej kub, acetone, ether, chloroform, benzene, acetic acid thiab alkali tov.
Naphthaleneacetic acid yog ib tug dav-spectrum cog kev loj hlob regulator, uas yuav txhawb cell faib thiab nthuav, induce tsim ntawm adventitious keeb kwm, nce txiv hmab txiv ntoo, tiv thaiv cov txiv hmab txiv ntoo poob, thiab hloov tus piv ntawm poj niam thiab txiv neej paj. Nws tuaj yeem nkag mus rau cov nroj tsuag los ntawm kev sib tw epidermis ntawm nplooj thiab ceg, thiab cov noob raug thauj mus rau tag nrho cov nroj tsuag nrog rau cov zaub mov txaus.
1-Naphthalene acetic acid (NAA) yog cov tshuaj tswj kev loj hlob ntawm cov nroj tsuag uas txhawb nqa cov nroj tsuag kev loj hlob thiab kev loj hlob. Ntxiv rau, 1-Naphthalene acetic acid muaj cov hauv qab no siv:
1. Cog kev loj hlob txhawb nqa: 1-Naphthalene acetic acid tuaj yeem siv los ua cov nroj tsuag kev loj hlob los txhawb cov nroj tsuag kev loj hlob thiab kev loj hlob, ua rau cov nroj tsuag loj hlob tuaj, thiab ua kom cov qoob loo nce ntxiv.
2. Txiv hmab txiv ntoo expansion agent: 1-Naphthalene acetic acid tuaj yeem siv los ua cov txiv hmab txiv ntoo nthuav tawm los txhawb cov txiv hmab txiv ntoo nthuav dav thiab nce cov txiv hmab txiv ntoo.
3. Txiv hmab txiv ntoo ripening tus neeg sawv cev: 1-Naphthalene acetic acid yuav siv tau raws li ib tug txiv hmab txiv ntoo ripening tus neeg sawv cev los txhawb cov txiv hmab txiv ntoo ripening thiab txhim kho txiv hmab txiv ntoo zoo.
4. Tar tshem tawm: 1-Naphthalene acetic acid tuaj yeem siv los ua cov tar tshem tawm kom tshem tawm cov tar hauv cov roj zoo thiab ua kom cov roj zoo du.
5. Pharmaceutical intermediates: 1-Naphthalene acetic acid tuaj yeem siv los ua cov tshuaj intermediates rau kev sib txuas ntawm qee cov tshuaj.
6. Dye intermediate: 1-Naphthalene acetic acid tuaj yeem siv los ua cov xim nruab nrab los ua ib co dyes.
7. Cov khoom siv hluav taws xob hluav taws xob: 1-Naphthalene acetic acid tuaj yeem siv los ua cov khoom siv hluav taws xob, xws li npaj cov khoom siv roj teeb.
Hauv kev xaus, 1-Naphthalene acetic acid muaj ntau yam kev siv hauv kev cog qoob loo, tshuaj, dyes thiab electrochemistry.
Synthesis ntawm Naphthalenacetic Acid:
Ntxiv 300Kg ntawm naphthalene thiab 100Kg ntawm chloroacetic acid rau lub reactor, ntxiv 2.5Kg ntawm hlau hmoov thiab 12Kg ntawm sodium bromide mus nqa tawm cov synthesis cov tshuaj tiv thaiv ntawm 210 degree, tom qab cov tshuaj tiv thaiv, ntxiv 600L dej thiab 85Kg ntawm 46 feem pua kua sodium hydroxide. mus rau lub reactor, nqa tawm cov tshuaj tiv thaiv ntawm 40 degree, kho tus nqi pH rau 10-11, pib chav distillation kom rov qab tau cov naphthalene unreacted, tom qab recovering cov naphthalene los ntawm distillation, twj tso kua mis aqueous tov uas muaj sodium naphthalene acetate rau hauv lub acidification tank. , thiab txias mus rau 40 DEG C, ntxiv qhov loj feem pua thiab yog 25 feem pua hydrochloric acid, kho pH tus nqi 5-6, tshem tawm cov impurity uas tsim nyob rau hauv cov tshuaj tiv thaiv hluavtaws, tom qab lim, ntxiv sodium chloride 180Kg hauv cov lim, ua kom cov ntsiab lus ntawm sodium chloride nyob rau hauv lub filtrate yog 20 feem pua (qhov loj piv ntawm sodium chloride thiab filtrate yog 20:80).
Tom qab txias mus rau 15 degree mus rau 20 degree rau 5 teev, thiab stirring rau lwm 3 teev, ib tug khoom precipitated thiab yog centrifuged. Cov filtrate tau los ntawm centrifugation yog sau rau tom ntej ntxiv thiab rov ua dua tom qab kev sib txuas ntawm naphthalene thiab chloroacetic acid tiav. Cov khoom tau txais tom qab centrifugation raug coj mus rau kev txheeb xyuas, thiab kev txheeb xyuas cov spectrum yog pom nyob rau hauv daim duab 3, thiab cov ntaub ntawv spectrum tau qhia hauv Table 1, thiab cov txiaj ntsig tau pom tias cov khoom yog sodium naphthalene acetate. Nqa cov khoom thiab evaporate cov dej kom qhuav rau hauv lub evaporating kettle, thiab tom qab ntawd pulverize kom tau 150Kg ntawm crude sodium naphthalene acetate nrog cov ntsiab lus ntawm 75 feem pua. Tom qab ntawd, naphthalenacetic acid tuaj yeem tau los ntawm acidification.
ua kom zoo:
Muab cov khoom nyoos ntawm naphthalene acetic acid rau hauv lub thoob hlau, ntxiv 50 zaug ntawm dej thiab 1 feem pua ntawm cov pa roj carbon activated (rau decolorization), thiab boil rau kub kub. Yog tias acidity txo qis, me ntsis acid tuaj yeem ntxiv kom pH ntawm 1-2. , Naphthalene acetic acid yog yaj nyob rau hauv dej kub, thiab tom qab me ntsis txias, ib tug dawb precipitate yog tau. Thaum nws precipitates, me ntsis roj dub tshwm nyob rau saum txheej ntawm cov tshuaj. Nws tseem muaj tshuaj yej acetic acid, thiab cov roj dub yog thawj zaug skimmed nrog rab diav. Thiab muab tso rau hauv lwm lub thoob hlau kom sov dua.
Lim cov tshuaj saum toj no thaum nws kub. Nws yog qhov zoo tshaj plaws kom sov ib txheej nyias ntawm cov paj rwb hauv qab daim ntaub lim kom tsis txhob muaj impurities los ntawm kev sib xyaw rau hauv cov khoom tiav. Cov filtrate crystallizes tom qab txias, thiab ces lim thiab dries (qis dua 70C') kom tau cov refined khoom ntawm naphthaleneacetic acid, uas yog dawb los yog liab me ntsis, nrog ib tug melting point ntawm 128-132 degree thiab ib txwm txias, nyob rau hauv cov duab ntawm koob. Cov muaju uas txias sai heev nrog dej khov yog cov hmoov me me.
Qee qhov tseem ceeb reactivity zog ntawm 1-Naphthaleneacetic acid (NAA) yog raws li nram no:
1. Acid-base neutralization cov tshuaj tiv thaiv: 1-Naphthalene acetic acid yog cov kua qaub uas tsis muaj zog, uas tuaj yeem nruab nrab nrog alkali los tsim cov ntsev sib xws.
2. Cov tshuaj tiv thaiv Esterification: 1-Naphthalene acetic acid tuaj yeem ua rau muaj cawv los tsim cov esters sib xws.
3. Cov tshuaj tiv thaiv carboxylic acid derivatives: 1-Naphthalene acetic acid tuaj yeem hnov mob nrog electrophilic reagents (xws li acylating reagents) los tsim cov carboxylic acid derivatives, xws li acid chlorides thiab esters.
4. Teb rau cov hlau ions: 1-Naphthalene acetic acid tuaj yeem tsim cov hlau ions (xws li Cu2 ntxiv), uas tuaj yeem siv los ua electrocatalyst rau cov tshuaj tiv thaiv electrochemical.
5. Carboxylate cov tshuaj tiv thaiv: 1-Naphthalene acetic acid tuaj yeem hloov pauv nrog cov organic nucleophiles (xws li imines thiab cawv) los tsim cov carboxylates sib xws.
Hauv cov ntsiab lus, qhov reactivity ntawm 1-Naphthalene acetic acid yog nplua nuj thiab muaj ntau haiv neeg, thiab cov tshuaj tiv thaiv no muab ntau txoj hauv kev rau kev npaj, synthesis, thiab hloov kho cov tshuaj lom neeg.