Beta-Hydroxyisovaleric Acidyog ib qho tseem ceeb ntawm cov khoom siv ntuj tsim los ua ib feem tseem ceeb hauv cov ntaub ntawv biochemical sib txawv hauv tib neeg lub cev thiab muaj kev sib txawv ntawm ntau lub lag luam. Qhov no tshwm sim tiag tiag metabolite, ntxiv rau lub npe hu ua -hydroxyisovaleric corrosive los yog BHIVA, yog ib qho khoom ntawm leucine digestion system thiab ua haujlwm tseem ceeb biomarker rau qee yam kev cuam tshuam ntawm metabolic. Nrog rau qhov sib npaug ntawm atomic C5H10O3, qhov tsis muaj kob crystalline muaj zog yog tus cwj pwm los ntawm nws cov qauv zoo, uas suav nrog hydroxyl sib sau ua ke thiab carboxylic corrosive sib sau ua ke. Raws li lub hauv paus tseem ceeb ntawm txoj kev hauv ob peb txoj hauv kev metabolic, beta-Hydroxyisovaleric Acid tau sib sau ua ke los ntawm cov kws tshuaj ntsuam thiab cov lag luam ib yam nkaus, tshwj xeeb tshaj yog nyob rau hauv cov chaw muag tshuaj, nutraceuticals, thiab biotechnology. Nws nyob ze rau hauv cov txheej txheem organic thiab nws cov kev siv tau zoo hauv cov ntu sib txawv ua rau nws yog qhov tseem ceeb ntawm kev txaus siab thiab qhov tseem ceeb.
Peb muab beta-Hydroxyisovaleric acid, thov xa mus rau lub vev xaib hauv qab no kom paub meej cov lus qhia thiab cov ntaub ntawv khoom.
Khoom siv:https://www.bloomtechz.com/synthetic-chemical/organic-intermediates/hmb-powder-cas-625-08-1.html
Dab tsi yog cov khoom siv tshuaj ntawm beta-Hydroxyisovaleric Acid?
Cov qauv tshuaj ntawmbeta-Hydroxyisovaleric acidNws yog tus cwj pwm los ntawm nws cov kab txuas txuas, suav nrog hydroxyl sib sau ua ke (-Kev zoo) txuas nrog beta carbon molecule txheeb ze rau carboxylic corrosive pawg (-COOH). Qhov kev nthuav qhia ntawm kev ua haujlwm no pab txhawb rau nws cov tshuaj lom neeg thiab cov khoom siv organic. Cov compound muaj atomic hnyav ntawm 118.13 g / mol thiab tshwm sim raws li ib tug dawb crystalline muaj zog nyob rau hauv chav tsev kub. Nws cov ntsiab lus yaj yog kwv yees li 85-87 degree , whereas nws bubbling point nyob ib ncig ntawm 245-247 degree ntawm tus qauv huab cua hnyav. Nyob rau hauv cov nqe lus ntawm dissolvability, beta-Hydroxyisovaleric Acid yog tolerably hnyav nyob rau hauv dej thiab profoundly hnyav nyob rau hauv lub polar natural solvents xws li ethanol thiab methanol. Qhov profile dissolvability no yog qhov yooj yim rau nws cov kev siv sib txawv thiab nws tus cwj pwm hauv cov txheej txheem ntuj tsim. Qhov sib xyaw ua ke qhia tau hais tias mellow causticity vim nws cov carboxylic corrosive pawg, nrog rau pKa kev hwm ntawm ib ncig ntawm 4.5, tso cai rau nws txaus siab rau cov lus teb ntawm cov kua qaub thiab cov ntsev nrog cov cations sib txawv.
Reactivity thiab Stability
Lub reactivity ntawm beta-Hydroxyisovaleric Acid yeej txiav txim siab los ntawm nws cov utilitarian bunches. Carboxylic corrosive moiety tuaj yeem muaj cov lus teb ib txwm muaj xws li esterification, amide kev npaj, thiab txo qis. Cov hydroxyl sib sau ua ke, ua ib qho dej cawv, tuaj yeem oxidized rau ketone los yog koom nrog cov lus teb parchedness. Hauv qab cov xwm txheej zoo li no, qhov sib xyaw ua ke yog qhov ruaj khov tab sis tuaj yeem muaj oxidation thaum tsis pom cov neeg ua haujlwm oxidizing khoom lossis lwj ntawm qhov kub thiab txias. Hauv cov txheej txheem organic, beta-Hydroxyisovaleric Acid koom nrog cov lus teb sib txawv ntawm cov enzymatic, tshwj xeeb tshaj yog nyob rau hauv txoj kev leucine catabolic. Nws lub suab nrov hauv kev npaj dej yog pH-nyob, nrog ntau lub suab nrov tau saib nyob rau hauv me ntsis acidic rau cov xwm txheej tsis ncaj ncees. Cov cuab yeej no yog qhov tseem ceeb rau nws txoj hauv kev hauv cov ntaub ntawv metabolic thiab nws siv hauv kev siv tshuaj thiab biotechnological.
Beta-Hydroxyisovaleric Acid siv li cas hauv cov txheej txheem metabolic?
Lub luag haujlwm hauv Leucine Metabolism
Beta-Hydroxyisovaleric Acid plays ib feem tseem ceeb hauv catabolism ntawm qhov tseem ceeb amino corrosive leucine. Nyob rau hauv txoj kev metabolic no, leucine yog pib nrog transaminated rau -ketoisocaproic corrosive, uas yog nyob rau ntawm qhov chaw oxidatively decarboxylated rau thav duab isovaleryl-CoA. Ua li no, isovaleryl-CoA hloov mus rau beta-Hydroxyisovaleric Acid los ntawm kev npaj ntawm cov lus teb enzymatic nrog rau cov protein -hydroxyisobutyryl-CoA hydrolase. Qhov kov no yog qhov tseem ceeb rau kev rhuav tshem thiab siv cov leucine, uas yog qhov yooj yim rau cov protein sib xyaw thiab tsim muaj zog hauv lub cev. Qhov ze ntawm beta-Hydroxyisovaleric Acid nyob rau hauv cov kua los yog cov ntshav tuaj yeem ua tus biomarker rau qee qhov kev cuam tshuam ntawm metabolic, tshwj xeeb tshaj yog cov uas cuam tshuam cov ceg- saw amino corrosive digestion system. Nqa cov qib ntawm cov tshuaj no tuaj yeem pom cov mob xws li maple syrup pee mob lossis isovaleric acidemia, ua rau nws muaj txiaj ntsig zoo hauv kev kho mob.
Kev koom tes hauv Kev Tsim Hluav Taws Xob
Dhau nws ib feem hauv leucine catabolism,beta-Hydroxyisovaleric acidmuaj nyob rau hauv vitality tiam cov ntaub ntawv nyob rau hauv lub cev. Raws li ib nrab ntawm kev tawg ntawm cov saw hlau amino acids, nws tuaj yeem hloov mus rau hauv acetyl-CoA thiab lwm cov metabolites uas txhawb nqa rau hauv lub voj voog citric corrosive, pab txhawb rau ATP era. Lub kaum sab xis ntawm nws txoj kev zom zaub mov underscores nws qhov tseem ceeb hauv cellular vitality homeostasis, tshwj xeeb tshaj yog nyob rau hauv cov ntaub so ntswg nrog siab vitality thov xws li skeletal leeg. Tom qab kev tshawb fawb tau pom zoo rau qhov muaj peev xwm rau beta-Hydroxyisovaleric Acid hauv kev ua haujlwm mitochondrial thiab oxidative stretch control. Qee qhov kev txiav txim siab tau pom tias nws yuav muaj cov khoom antioxidant, muaj peev xwm ua kom cov hlwb los ntawm kev puas tsuaj oxidative. Qhov ob feem ntawm qhov tseem ceeb ntawm kev zom zaub mov thiab kev ruaj ntseg ntawm tes qhia txog qhov tseem ceeb hauv kev ua kom zoo thiab loj metabolic noj qab haus huv.
Kev siv ntawm beta-Hydroxyisovaleric Acid nyob rau hauv ntau yam lag luam
Hauv kev lag luam kws tshuaj, beta-Hydroxyisovaleric Acid tau txais kev saib xyuas rau nws cov kev siv tshuaj kho mob. Kev tshawb fawb txuas ntxiv mus tshawb nrhiav nws txoj kev siv los kho cov kab mob metabolic, tshwj xeeb yog cov uas cuam tshuam nrog cov kab mob sib txuas ntawm cov amino acid metabolism. Qee cov kev tshawb fawb tau tshawb xyuas nws lub peev xwm ua biomarker rau kev tshawb pom ntxov ntawm insulin tsis kam thiab ntshav qab zib hom 2, qhib txoj hauv kev rau kev tiv thaiv tshuaj thiab kev kho mob tus kheej. Lub nutraceutical sector kuj tau qhia kev txaus siab rau beta-Hydroxyisovaleric Acid vim nws txoj kev koom tes hauv lub zog metabolism. Qee cov khoom noj khoom haus suav nrog qhov sib xyaw no lossis nws cov precursors, thov cov txiaj ntsig zoo rau kev ua kis las thiab rov qab los. Txawm li cas los xij, nws tseem ceeb heev uas yuav tsum nco ntsoov tias kev tshawb fawb ntxiv yog xav tau los ua kom pom tseeb cov lus thov no thiab nkag siab txog cov txiaj ntsig ntev ntawm kev ntxiv.
Muaj thiab Biotechnological Applications
Tshaj nws txoj haujlwm lom neeg,beta-Hydroxyisovaleric acidpom cov ntawv thov hauv ntau cov txheej txheem kev lag luam. Hauv kev lag luam tshuaj, nws ua haujlwm ua ntej rau kev sib txuas ntawm lwm cov khoom tseem ceeb, suav nrog qee yam polymers thiab cov tshuaj tshwj xeeb. Nws cov qauv tshwj xeeb ua rau nws nthuav lub tsev thaiv kev tsim cov ntaub ntawv nrog cov khoom tshwj xeeb. Hauv biotechnology, beta-Hydroxyisovaleric Acid yog siv rau hauv kev tsim cov biosensors thiab cov cuab yeej kuaj mob. Nws muaj nyob rau hauv cov kua roj ntsha tuaj yeem kuaj pom thiab ntsuas, ua rau nws muaj txiaj ntsig zoo rau kev saib xyuas cov xeev metabolic lossis txheeb xyuas qee yam kab mob. Tsis tas li ntawd, cov txheej txheem metabolic tau raug kawm rau cov kev siv hauv cov txheej txheem metabolic, qhov twg cov kab mob tuaj yeem hloov kho los tsim cov tshuaj muaj txiaj ntsig lossis tshuaj.
Hauv kev xaus,beta-Hydroxyisovaleric acidyog ib tug multifaceted compound nrog lub luag hauj lwm tseem ceeb nyob rau hauv cov kab mob lom thiab ntau yam kev siv nyob rau hauv ntau yam industries. Nws qhov tseem ceeb hauv cov txheej txheem metabolic, ua ke nrog nws lub peev xwm hauv kev siv tshuaj, nutraceutical, thiab kev lag luam, ua rau nws muaj kev tshawb fawb thiab kev loj hlob tsis tu ncua. Raws li peb txoj kev nkag siab ntawm qhov sib xyaw no loj hlob tuaj, peb tuaj yeem cia siab tias yuav pom kev siv tshiab thiab cov ntawv thov tshwm sim yav tom ntej. Yog xav paub ntxiv txog nws thiab lwm yam khoom siv tshuaj, thov hu rau peb ntawmSales@bloomtechz.com.
Cov ntaub ntawv
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