Tetracaine hydrochloride, feem ntau hu ua Tetracaine HCl, yog ib qho tshuaj loog muaj zog hauv zos uas tau siv dav hauv ntau daim ntawv thov kev kho mob tau ntau xyoo. Qhov ntau yam sib xyaw ua ke no ua lub luag haujlwm tseem ceeb hauv kev tswj qhov mob thiab tau dhau los ua cov cuab yeej tseem ceeb hauv kev lag luam kho mob. Hauv phau ntawv qhia dav dav no, peb yuav tshawb txog kev siv, cov txiaj ntsig, thiab kev txiav txim siab ntawmTetracaine HCl hmoov, tso lub teeb ntawm nws qhov tseem ceeb hauv cov tshuaj niaj hnub.
Peb muab tetracaine hydrochloride, thov xa mus rau lub vev xaib hauv qab no kom paub meej cov lus qhia thiab cov ntaub ntawv khoom.
Khoom siv:https://www.bloomtechz.com/synthetic-chemical/api-researching-only/tetracaine-hcl-cas-136-47-0.html
Kev Tshawb Fawb Tom Qab Tetracaine HCl: Nws Ua Haujlwm Li Cas
Tetracaine hydrochloride (HCl), ib qho tshuaj sedative nyob ze, muaj peev xwm los ntawm kev txiav txim siab biochemical kom muaj kev cuam tshuam los ntawm kev tsis xis nyob. Tetracaine's ester linkage, tshwj xeeb yog 2-(dimethylamino)ethyl 4-butylaminobenzoate qauv, yog dab tsi ua rau nws muaj zog ester-hom tshuaj loog. Thaum thov, tetracaine HCl nkag mus rau hauv lub cev thiab hla cov yeeb yaj kiab ntawm tes vim nws qhov lipophilic xwm. Thaum nyob rau hauv cov paj hlwb, tetracaine siv nws cov khoom los ntawm kev tsom mus rau thiab txwv tsis pub muaj hluav taws xob-gated sodium diverts nyob rau hauv cov txheej txheem neuronal. Cov kab hluav taws xob sodium no yog qhov tseem ceeb rau kev sib kis ntawm kev ua ub no, kev txhawb zog hluav taws xob uas sib txuas lus cov ntaub ntawv pom tau, suav nrog kev tsim txom, los ntawm cov hlab ntsha mus rau lub focal sensory system.
Tetracaine muaj peev xwm tswj tau cov sodium channel hauv lawv lub xeev tsis muaj zog vim tias nws muaj kev sib raug zoo tshwj xeeb rau lawv. Nws muaj txiaj ntsig zoo tiv thaiv sodium ions, uas tsim nyog rau kev ua haujlwm muaj peev xwm lub sijhawm depolarization, los ntawm kev nkag mus rau ntawm tes. Qhov tsim nyog ionic flux uas pib thiab propagates paj hlwb impulses yog tiv thaiv los ntawm thaiv cov channel. Yog li, cov paj hlwb nyob rau hauv qhov chaw uas tetracaine siv tsis tuaj yeem sib txuas lus torment cim rau lub paj hlwb, yog li muab kev txwv tsis pub muaj kev tsis xis nyob. Neuronal excitability thiab paj hlwb impulse tiam thiab kev sib kis yog ob qho tib si txo qis thaum sodium channels raug thaiv.
Tetracaine's siab affinity rau sodium raws thiab nws lub peev xwm los thaiv cov channel txawm nyob rau hauv tsawg concentrations account rau nws potency. Nws lub sijhawm ntev ntawm kev txiav txim yog ua tau los ntawm nws cov potency siab, uas yog qhov zoo rau cov txheej txheem uas yuav tsum tau siv tshuaj loog ntev. Txawm li cas los xij, cov khoom zoo heev uas ua rau tetracaine ua tiav zoo ib yam yuav tsum tau ceev faj kom tsis txhob muaj kev phom sij hauv paus. Thaum siv kom haum, tetracaine muab cov khoom zoo thiab nthuav dav los ntawm kev tsis xis nyob nrog cov txiaj ntsig tsis zoo tom qab. Tsis tas li ntawd, nws qhov kev pib sai sai ua rau nws tsim nyog rau ob qho tib si luv luv thiab ntev lub zog hauv zej zog sedation. Hauv cov chaw kho mob, tetracaine yog siv rau hauv ntau daim ntawv thov, suav nrog cov txheej txheem ophthalmic, tshuaj dermatological, thiab ua tus pab cuam hauv ntau hom kev sedation, qhia txog nws qhov kev hloov pauv thiab muaj peev xwm hauv kev saib xyuas kev tsim txom. Hauv qhov no, kev tshawb fawb tom qab tetracaine HCl qhia txog nws txoj haujlwm raws li qhov muaj txiaj ntsig zoo nyob ze sedative, siv nws cov kev koom tes biochemical nrog cov chaw noj tshuaj sodium los nthuav qhia kev mob siab rau thiab ncua qhov mob.
Kev Siv Kho Mob: Qhov twg Tetracaine HCl ci
Tetracaine HCl hmoovpom daim ntawv thov hauv ntau cov txheej txheem kho mob thiab kev kho mob. Nws cov versatility thiab kev ua tau zoo tau ua rau nws mus rau kev xaiv rau cov kws kho mob hauv ntau qhov chaw. Cia peb tshawb xyuas qee qhov kev siv tseem ceeb ntawm qhov sib xyaw zoo kawg no:
Ophthalmology:
Tetracaine HCl feem ntau yog siv rau hauv qhov muag tee rau cov txheej txheem xws li tonometry ( ntsuas qhov siab ntawm lub qhov muag) thiab kev phais qhov muag me. Nws muab ceev thiab zoo loog ntawm lub cornea thiab conjunctiva, tso cai rau kev soj ntsuam zoo thiab kev cuam tshuam.
01
Kev kho hniav:
Hauv kev kho hniav, Tetracaine HCl hmoov feem ntau yog siv los ua tshuaj loog ua ntej txhaj tshuaj lossis cov txheej txheem me. Nws pab txo qhov tsis xis nyob cuam tshuam nrog kev kho hniav, ua rau kev kho mob ntau dua rau cov neeg mob.
02
Otolaryngology:
Cov kws kho mob pob ntseg, qhov ntswg, thiab caj pas siv Tetracaine HCl rau ntau cov txheej txheem, suav nrog kev kuaj qhov ntswg, laryngoscopies, thiab kev phais me hauv cov cheeb tsam no. Nws muaj peev xwm ua rau cov mucous membranes ua rau nws muaj txiaj ntsig tshwj xeeb hauv daim teb no.
03
Dermatology:
Tetracaine HCl yog ua haujlwm nyob rau hauv cov txheej txheem dermatological xws li daim tawv nqaij biopsies, kho laser, thiab kev phais me. Nws pab txo qhov mob thiab tsis xis nyob thaum cov kev cuam tshuam no.
04
Pain Management:
Qee zaum, Tetracaine HCl hmoov yog siv rau hauv cov tshuaj pleev ib ce rau kev tswj cov mob ntev, muab kev pab hauv zos yam tsis muaj kev phiv tshuaj.
05
Kev siv ntau yam qhia tau hais tias muaj ntau yam thiab qhov tseem ceeb ntawm Tetracaine HCl hmoov hauv cov tshuaj niaj hnub. Nws lub peev xwm los muab cov hom phiaj, kev siv tshuaj loog zoo tau hloov pauv ntau txoj kev kho mob, txhim kho cov neeg mob kev nplij siab thiab pab txhawb kev cuam tshuam ntau dua.
Kev txiav txim siab txog kev nyab xeeb thiab muaj peev xwm cuam tshuam
Thaum Tetracaine HCl hmoov feem ntau suav hais tias muaj kev nyab xeeb thiab siv tau zoo thaum siv raws li qhia, nws yog qhov tseem ceeb kom paub txog cov kev mob tshwm sim thiab kev saib xyuas kev nyab xeeb. Raws li nrog rau txhua yam tshuaj, kev siv kom raug thiab kev saib xyuas kev tshaj lij yog qhov tseem ceeb kom txo qis kev pheej hmoo thiab ua kom cov txiaj ntsig zoo.
Qee qhov kev mob tshwm sim ntawm Tetracaine HCl tuaj yeem suav nrog:
Kev khaus hauv zos lossis kub hnyiab ntawm qhov chaw thov
Kev tsis haum tshuaj (tsis tshua muaj, tab sis tuaj yeem tshwm sim hauv cov tib neeg rhiab heev)
Methemoglobinemia (ib qho tsis tshua muaj tab sis mob hnyav cuam tshuam rau cov ntshav oxygen qib)
Systemic toxicity yog absorbed nyob rau hauv ntau ntau
Txhawm rau kom muaj kev nyab xeeb sivTetracaine HCl hmoov, cov kws kho mob yuav tsum:
Nws tsim nyog sau cia tias Tetracaine HCl yuav tsum tsuas yog siv raws li kev saib xyuas ntawm cov kws kho mob uas tau kawm. Kev tswj hwm tus kheej lossis siv tsis raug tuaj yeem ua rau muaj teeb meem loj thiab yuav tsum zam.
Xaus
Hauv kev xaus, Tetracaine HCl hmoov sawv ua lub hauv paus hauv kev siv tshuaj loog hauv zos, muab cov kev mob hnyav thiab ua kom muaj ntau yam kev kho mob. Nws versatility, pib sai sai, thiab ntev ntev ua rau nws yog ib qho tseem ceeb indispensable cuab tam nyob rau hauv kev kho mob. Los ntawm kev tshuaj xyuas qhov muag mus rau cov txheej txheem kho hniav thiab kev cuam tshuam dermatological, Tetracaine HCl txuas ntxiv ua lub luag haujlwm tseem ceeb hauv kev txhim kho cov neeg mob kev nplij siab thiab txhawb kev kho mob.
Raws li kev tshawb fawb hauv chaw muag tshuaj thiab kev tswj xyuas qhov mob tau nce mus, peb yuav pom cov ntawv thov tshiab thiab cov qauv ntawm Tetracaine HCl tshwm sim, ntxiv nthuav nws cov txiaj ntsig hauv tshuaj. Txog tam sim no, qhov sib xyaw zoo kawg no tseem yog ib feem tseem ceeb hauv arsenal ntawm cov kws kho mob thoob ntiaj teb, pab ua kom cov txheej txheem kho mob yooj yim dua thiab tswj tau rau cov neeg mob suav tsis txheeb txhua hnub.
Yog tias koj yog ib tus kws kho mob lossis kws tshawb fawb xav paub ntxiv txogTetracaine HCl hmoovthiab nws cov ntawv thov, tsis txhob yig tiv tauj mus rau cov chaw muag khoom muaj koob npe kom paub ntau ntxiv. Nrog rau kev siv thiab kev nkag siab zoo, Tetracaine HCl tuaj yeem ua rau muaj kev cuam tshuam tseem ceeb hauv kev siv tshuaj loog hauv zos thiab kev tswj xyuas qhov mob.
Cov ntaub ntawv
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Heavner, JE (2007). Local tshuaj loog. Kev xav tam sim no hauv Anaesthesiology, 20(4), 336-342.
Malamed, SF (2019). Phau ntawv ntawm tshuaj loog hauv zos. Elsevier Health Sciences.
Rosenberg, PH, Veering, BT, & Urmey, WF (2004). Qhov siab tshaj plaws pom zoo koob tshuaj loog hauv zos: lub tswv yim multifactorial. Regional Anesthesia & Pain Medicine, 29(6), 564-575.
Tetzlaff, JE (2000). Pharmaology ntawm lub zos tshuaj loog. Lub Tsev Kho Mob Tshuaj Kho Mob ntawm North America, 18(2), 217-233.