Cov tshuaj sib txuas nrog kev siv ntau yam,N-carbetoxy -4- piperidoneyog qhov tseem ceeb hauv nruab nrab hauv ntau cov txheej txheem hluavtaws sib txawv. Qhov qauv moleecule, nrog nws cov qauv qauv thiab reactrityity, muaj lub nkoj tseem ceeb heev rau hauv cov teb ntawm cov organic chemistry thiab kev tsim kho tshuaj. Hauv txoj kev tshawb nrhiav no, peb yuav delve rau hauv cov ntawv thov, tseem ceeb, thiab cov txiaj ntsig ntawm n-carbetidone ua qhov tseem ceeb hauv kev siv tshuaj thiab kev pom zoo nkauj niaj hnub.
Khoom Code: BM -2-1-349
Tus lej lej: 29976-53-2
Molecular Cov Qauv: C8H13No3
Molecular hnyav: 171.19
Einecs tus naj npawb: 249-984-5
MDL tsis muaj.: MFCD00006188
HS code: 29333999
Analysis items: HPLC>99. {{0%, lc-ms
Kev Lag Luam Tseem Ceeb: Tebchaws Asmeskas, Australia, Nyij Pooj, Tebchaws Yelemees, Indonesia, UK, New Zealand, Canada thiab lwm yam.
Chaw tsim tshuaj paus: BLOOM Tech Changzhou Hoobkas
Kev Pab Technology: R & Dept. {-4
Peb muab n-carbethoxy -4- Piperidone, thov saib mus rau lub vev xaib hauv qab no rau cov ncauj lus qhia ntxaws ntxaws thiab cov ntaub ntawv cov ntaub ntawv.
Cov ntawv thov ntawm n-carbethoxy -4- piperidone hauv synthesis
N-carbethoxy -4- Piperidone yog qhov tseem ceeb tshaj plaws uas yog lub tsev tseem ceeb thaiv nyob rau hauv cov synthesis ntawm ntau cov complex organic molecules. Nws tus nqi nyob hauv cov pab pawg muaj txiaj ntsig zoo nkauj thiab muaj cov carbetoxy moami, uas ua rau nws tau pib ua tau zoo tshaj plaws rau ntau yam tshuaj hloov tshuaj. Cov pab pawg ua haujlwm no muab ntau lub sijhawm rau kev ua haujlwm thiab kev hloov kho, ua rau n-carbetidone Ib qho kev kawm tseem ceeb hauv kev kawm thiab kev lag luam tshuaj lom neeg thiab kev lag luam synthesis.
Ib qho ntawm cov ntawv thov tseem ceeb tshaj plaws ntawmN-carbethoxy -4- Piperidone (https://www.sigmaoaldrich.com/de/de/sasach/}? Fole {3} } Cov Khoom & Nplooj =1 {{5} {{{{}}} {9}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} yog nyob rau hauv synthesis ntawm heterocyclic teb. Piperidone ntiv nplhaib ua ua scaffold ruaj khov, pub cov kws kho mob los tsim cov qauv sib txawv thiab ua kom muaj kev ua haujlwm tshiab. Qhov no ua rau nws tshwj xeeb tshaj nyob hauv kev tsim cov alkaloids, uas yog nitrogen-muaj cov organic sib txuas nrog kev ua haujlwm tseem ceeb. Ntau cov alkaloids, suav nrog cov uas muaj peev xwm ntawm n-carbethoxy {2}} Piperidone, ua rau nws tseem ceeb hauv kev tshuaj thiab tshuaj chemistry.
Tshaj li heterocyclic synthesis, n-carbethoxy -4- piperidone yog instrumental nyob rau hauv kev tsim ntawm ntau pawg ua haujlwm. CarboronyL pab pawg yog reactive heev thiab tuaj yeem yuc getoSophilic ntxiv thiab tuaj yeem txuas ntxiv nrog ntau ntawm nucleophiles, saib xyuas cov lus qhia ntawm cov neeg hloov chaw sib txawv. Tsis tas li ntawd, pab pawg carbetoxy carbetoxy muaj cov avenues ntxiv rau kev ua haujlwm. Piv txwv li, nws tuaj yeem yog hydrolyzed los ua cov roj carboxylic lossis txo kom muaj cawv, muab cov tshuaj tua kab mob, muab cov tshuaj lom neeg nrog kev xaiv dav ntawm cov qauv ntawm cov qauv.
Lwm qhov tseem ceeb tshaj plaws ntawm n-carbethoxy -4- Piperidone yog nws daim ntawv thov hauv cov kev cuam tshuam ntau. Cov kev tawm tsam no muaj feem cuam tshuam cov synthesis ntawm cov molecules hauv ib kauj ruam, sib txuas ua ke los tsim cov khoom xav tau. Lub nplhaib piperidone yog cov kev hloov siab heev hauv cov txheej txheem zoo li no, uas ua rau n-carbetoxy {3}} paeridone ib feem muaj txiaj ntsig hauv kev txhim kho molecular. Cov tsev qiv ntawv no tseem ceeb rau kev tshuaj pom kev, raws li lawv tau muab ntau cov neeg muaj peev xwm sib tw rau kev ntsuam xyuas ntxiv hauv kev ntsuas roj ntsha.
Zuag qhia tag nrho, n-carbethoxy -4- Piperidone yog qhov kev tsim cov khoom siv hluavtis muaj txiaj ntsig zoo, tshwj xeeb hauv cov tshuaj kho mob thiab tshuaj pom tshuaj. Nws cov tshuaj lom neeg tshwj xeeb thiab cov khoom siv rau nws ua rau muaj qhov tsis tseem ceeb ntawm cov kws tshawb nrhiav thiab cov kws tsim khoom sib xws.
N-carbetoxy -4- Piperidone lub luag haujlwm hauv kev tsim kho
Cov kev lag luam kws tshuaj tau lees paub txog qhov muaj peev xwm ntawmN-carbetoxy -4- piperidoneRaws li qhov tseem ceeb hauv nruab nrab hauv cov tshuaj synthesis. Nws cov qauv tsim ua kom nws muaj kev ntxim nyiam pib rau kev txhim kho ntawm ntau yam kev kho mob.
Ib qho ntawm cov kev koom tes tseem ceeb tshaj plaws ntawm n-carbethoxy {1}} Piperidone rau cov kws tshawb fawb tshawb fawb lus dag hauv nws lub luag haujlwm hauv cov synthesis ntawm analgesics. Lub nplhaib piperidine, uas ua rau cov tseem ceeb ntawm cov txheej txheem nruab nrab no, yog ib qho kev siv tshuaj uas muaj ntau yam tshuaj mob-releving. Los ntawm kev siv n-carbethoxy {4}} Piperidone, chemists tuaj yeem tsim cov khoom tshiab uas muaj peev xwm txhim kho kev ua tau zoo thiab txo cov kev mob tshwm sim.
Tshaj li kev tswj hwm qhov mob, qhov no feem ntau qib nrab tau pom cov ntawv thov hauv kev txhim kho antihizertensive cov neeg sawv cev. Lub peev xwm los ua haujlwm piperide ntiv nplhaib tso cai rau cov kws tshawb fawb zoo, ua rau lawv cov kev sib cuam tshuam nrog kev sib txuam ntawm cov ntshav siab.
N-carbethoxy -4- Piperidone tseem ua lub luag haujlwm tseem ceeb hauv kev sib koom tes ntawm cov tshuaj tiv thaiv kev ntxhov siab thiab kev ntxhov siab. Cov Piperidine Scaffold yog tam sim no nyob rau hauv ntau cov tshuaj muaj kev lag luam tsom iav kev mob hlwb. Los ntawm kev ua haujlwm nruab nrab no, kws kho mob tuaj yeem tshawb xyuas cov chaw tshiab thiab tsim cov lus sib txuas tshiab nrog kev txhim kho kho cov ntaub ntawv kho mob.
Tsis tas li ntawd, cov nqi hluav taws xob ntawm N-Carbethoxy {1}}} piperidone txuas rau lub realm ntawm antimicrobial kev tshawb fawb. Nws cov kev cuam tshuam rau kev sib koom tes ntawm ntau pawg neeg ua haujlwm uas tuaj yeem muab cov tshuaj tua kab mob lossis cov tshuaj tiv thaiv kab mob rau cov molecules. Cov versatility no ua rau nws muaj txiaj ntsig zoo hauv kev sib ntaus sib tua tiv thaiv kab mob sib kis thiab kev hem thawj ntawm kev tiv thaiv antimicrobial.
Cov txiaj ntsig tseem ceeb ntawm kev siv n-carbethoxy {1}}} piperidone hauv tshuaj lom neeg cov tshuaj tiv thaiv
Cov thoob plaws kev saws me nyuam ntawmN-carbetoxy -4- piperidoneRaws li nrab hauv nruab nrab hauv cov synthic synthesis tuaj yeem yog ob peb cov txiaj ntsig tseem ceeb nws muab rau cov kws kho mob thiab cov kws tshawb nrhiav:
Lub xub ntiag ntawm ob qho tib si reactive carboronyl pawg thiab carbetoxy moiety muab ntau cov ntsiab lus rau kev ua haujlwm. Qhov kev hloov pauv no tso cai rau cov neeg siv tshuaj tua hluav taws xob hluavtaws hluavtaws thiab nkag mus rau ntau hom kev sib tw ntawm cov khoom pib.
Piperidone Ring ua haujlwm ua ib qho scaffold uas tuaj yeem yog elaborated los tsim cov lus sib txuas nrog cov qauv peb-seem. Qhov kev tsim qauv no yog muaj txiaj ntsig tshwj xeeb hauv kev tshuaj yeeb tshuaj, qhov twg tshawb xyuas cov duab molecular sib txawv tuaj yeem ua rau cov cim ntawm cov neeg tshiab cov tebchaw.
N-carbethoxy -4- Piperidone muaj cov hauv kev rau kev hloov pauv ntawm kev ua kom tiav. Lub peev xwm los tswj cov kev sib tw ntawm cov kev tawm tsam yog qhov tseem ceeb hauv kev saib xyuas ntawm atoms tuaj yeem cuam tshuam ntau lub compound kev ua haujlwm biological.
Cov kev hloov kho nruab nrab no yog qhov zoo rau cov txheej txheem hluavtaws niaj hnub, suav nrog kev hloov tsheb hlau-catalyzed, organocatalysis, thiab cov tshuaj chemical. Nws cov kev sib raug zoo nrog cov txheej txheem siab tshaj plaws txhim kho nws cov nqi hluav taws xob ua cov chaw kawm thiab kev lag luam.
N-carbethoxy -4- Piperidone tuaj yeem npaj tau cov khoom siv khoom siv tau, kom muaj kev ntseeg tau rau cov txheej txheem kev tsim khoom. Qhov kev ntsuas ntsuas ntsuas no yog qhov tseem ceeb rau kev ua lag luam ntau lawm ntawm cov kws tshuaj thiab lwm yam tshuaj zoo.
Tag
Hauv kev xaus, n-carbethoxy -4- Piperidone sawv tawm raws li ib qho kev sib txuam zoo thiab muaj txiaj ntsig nruab nrab hauv cov organic synthesis. Nws cov ntawv thov ncua los ntawm kev tsim cov hetercycycles rau kev txhim kho cov kws tshuaj ntsuam lub neej. Qhov tshwj xeeb cov txheej txheem nta thiab reactivity ntawm no compound ua rau nws tsis tseem ceeb ntawm cov kws lij choj ntawm cov khoom siv ntau yam nrog cov qauv ntau ntawm cov neeg muaj ntau yam.
As research in organic chemistry and drug discovery continues to advance, the role of N-Carbethoxy-4-piperidone as an intermediate is likely to expand further. Nws muaj peev xwm los pab kho cov kev tshawb fawb ntawm qhov chaw tshuaj lom neeg thiab pab txhawb rau kev txhim kho kev kho cov neeg sawv cev tshiab uas tsis muaj kev kawm thiab kev teeb tsa chaw. Los ntawm harnessing lub peev xwm ntawm cov neeg sib txuas no, cov kws tshawb fawb tuaj yeem sib thawb cov ciaj ciam ntawm cov khoom siv hluav taws xob hluavtaws thiab tsav tsheb tshiab hauv kev lag luam.
Koj puas xav paub txog lub peev xwm ntawm n-carbethoxy {1}}} Piperidone rau koj kev tshawb fawb lossis kev siv cov khoom siv? Peb pab neeg ntawm cov kws tshaj lij ntawm Bloom Tech nyob ntawm no los pab koj. Nrog peb cov kev paub ntau hauv kev cai synthesis thiab teev-nce ntau lawm, peb tuaj yeem muab cov zooN-carbetoxy -4- piperidonethiab cov feem sib xyaw sib xyaw ua kom haum rau koj cov kev xav tau tshwj xeeb. Tiv tauj peb ntawmSales@bloomtechz.comLos tham txog yuav ua li cas peb tuaj yeem txhawb nqa koj cov phiaj xwm kev ua haujlwm thiab pab coj koj cov tswv yim rau fruition.
Ntawv Sawv cev
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Lee, MH, li al. (2019). N-carbethoxy -4- Piperidone ua tus tseem ceeb hauv nruab nrab hauv kev txhim kho cov tshiab analgesics. Kev tshawb fawb tshuaj xyuas cov tshuaj, 28 (6), {5 5}}.
Zhang, Y., & Wang, Q. (2021). Tsis ntev los no kev hloov kho hauv kev siv N-Carbethoxy {2}} Piperidone rau cov hluavtaws ntawm cov sib txuas ua ke. Tshuaj xyuas tshuaj xyuas, 121 (15), 9287-9320.
Rodriguez, Al, Thompson, CM (2018). Cov kev hloov pauv tsis sib xws ntawm n-carbethoxy {2}} Piperidone: Cov ntawv thov nyob rau hauv tag nrho Synthesis. AngewandTe Chemie International Edition, 57 (22), {5}}.