Teb ntawm cov kev kho mob regenerat thiab kev mob metabolic muaj kev kho mob sai, uas tau tsav los ntawm kev tawg hauv peptide {{}}} raws cov kev kho mob. Ntawm cov no,Nasc, Tus kab mob, thiabBPC157tau tawm raws li kev cog lus sib tw vim lawv cov txheej txheem tshwj xeeb ntawm kev ua thiab ntau yam kev siv cov ntawv thov sib kho. Cov ntawv no tshawb txog cov txheej txheem molecular, kev kho mob muaj peev xwm, thiab kev nyab xeeb tshaj plaws ntawm cov nqaij mos, thiab anti- kev cuam tshuam kev cuam tshuam.
Cov txheej txheem ua lag ua luam
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MOTSC: Ib qho mitochondrial - derived peptide rau cov teeb tsa metabolic
Tshawb Nrhiav thiab Molecular yam ntxwv
MOTSC (Mitochondrial qhib nyeem ntawv ncej ntawm kaum ob s c {{} {{5} {{1} - acid peptide los ntawm mitochondyred genome. Tshawb pom nyob rau hauv 2015, nws sawv cev rau ib chav tshiab ntawm mitochondrial {{7} Muab cov pa roj meptolism thiab cov lus teb kev ntxhov siab. Tsis zoo li ib txwm muaj cov protein-motsc yog synthesized nyob rau hauv cytopondria thiab tso tawm mus rau hauv cytoplasm, uas nws modulates tseem ceeb meatolic pathways.
► Cov tshuab ua
MOTSC nthuav nws cov teebmeem los ntawm ntau txoj kev:
Ampk ua kom: nws txhim kho amp - ™ activ່ວນ} agnase ™ activ່ວນ ™ activ່ວນ ດ່ວນ activ activ activ (AMPK) Kev piav qhia ntawm lub zog thivpostasis. Qhov no txhawb nqa cov kua dej qab zib thiab cov roj ntsha thiab cov roj ntsha oxidation, txhim kho cov insulin rhiab.
Folate -}} Txheem Folate thiab Poloscthentesis, tseem ceeb rau Nucleotide kev tsim thiab DNA kho.
Kev Tiv Thaiv Kev Nyuaj Siab: Nyob rau hauv kev ntxhov siab oxidative, motscidative kev ntxhov siab, motscurc upregulates antioxidant enzymes (piv txwv, sod2), txo cov sod2), txo qis cellular puas tsuaj.
Anti {-} Kev ua kev kub ntxhov: Kev tshawb nrhiav tsiaj qhia tias MotSC txuas ntxiv power1 thiab PGC-1, cov noob uas txuas nrog kev ua neej ntev.
Encial daim ntawv thov
Ntshav qab zib thiab kev rog: MOTSC txhim kho cov kua pleevzos -}} Cov miv liab los ntawm kev txhim kho pob txha pob txha taub hau. Tib neeg cov kev sim siab yuav soj ntsuam nws txoj kev ua tau zoo hauv Metabolic Syndrome.
Kev qoj ib ce: Motsc
Kev Tiv Thaiv Kev Tiv Thaiv Kev Tiv Thaiv Kev Tiv Thaiv Kev Tiv Thaiv Kab Mob
► Kev Nyab Xeeb thiab Txwv
MOTSC zoo nkaus li zoo -}}}}}}}}}}}}}}}}}}}}} Tsis muaj tus qauv tsiaj, uas tsis muaj qhov tseem ceeb toxicity qhia. Txawm li cas los xij, tib neeg kev tshawb fawb tau txwv, thiab ntev - lub sij hawm kev nyab xeeb tseem tsis tau hloov. Kev tswj xyuas hurdles mob hnyav vim nws cov keeb kwm mitochondor, uas ua rau cov txheej txheem pom zoo no.
TB500: Ib qho thymosin tawg rau cov ntaub so ntswg kho
► Keeb kwm thiab qauv
TB500 yog cov hluavtaws peptide derived los ntawm thymosin beta {}} 4 (tb4), muaj 43-amino acid protein ib txwm ua los ntawm thymic epithelial cells thiab ntau cov ntaub so ntswg. TB500 khaws cia TB4 cov cheeb tsam nquag (AC-LKKTETQ), ua kom nws kho kom lub qhov txhab zoo thiab cov ntaub so ntswg.
► Cov txheej txheem ntawm kev ua
TB500's Regenerative Cov Khoom Muag Los Ntawm:
Angiogenesis: Nws pab txhawb cov hlab ntsha los ntawm kev ua siab ntev vegf thiab FGF, txhim kho ntshav rau thaj chaw raug mob.
Kev tsiv teb chaws Kiv teb chaws: TB500 txhim kho keratinocyte thiab endothelial cell lub zog, nrawm txhab qhov ntshai kaw.
Collagen Tso Npe: Nws txhawb nqa collagen synthesis, ntxiv dag zog txuas cov ntaub so ntswg sib txuas hauv cov tonsons, ligaments, thiab cov leeg.
Anti {-}} Kev txo cov lus (piv txwv li, tnf -
Encial daim ntawv thov
Cov leeg raug mob: TB500 yog dav siv hauv kev ua kis las kho mob los kho cov leeg nyhav, cov leeg leeg, thiab cov leeg leeg ua kom nruj. Anecdotal Cov Ntawv Tshaj Tawm qhia nws lub sijhawm luv sijhawm los ntawm 30-50%.
Kev mob khaub thuas: Cov mob ntshav qab zib thiab lub siab sores qhia tau zoo dua tus nqi kho mob nrog TB500, yuav zoo rau lub Angiogenesis.
Cov plaub hau kev loj hlob: Cov Kev Tshawb Fawb Txog TB500 yuav rov qab Androgenetic alopecia los ntawm kev txhawb nqa dermal papilla cell proliferation.
► Kev nyab xeeb thiab kev sib cav
Thaum TB500 feem ntau suav hais tias muaj kev nyab xeeb, nws cov kev cai tswj hwm yog tsis meej xwm. Hauv Asmeskas, nws tau faib ua kev tshawb fawb tshuaj, tsis pom zoo rau tib neeg siv los ntawm FDA. Cov kev mob tshwm sim muaj tsawg heev tab sis yuav suav nrog kev txhaj tshuaj -} kev khaus khaus lossis mob siab rau mob taub hau lossis mob siab rau mob taub hau lossis mob siab mob taub hau lossis mob siab rau mob taub hau. Cov neeg ncaws pob yuav tsum nco ntsoov tias TB500 yog txwv los ntawm Wada vim nws qhov kev ua tau zoo - kev txhim kho muaj peev xwm.
BPC157: lub plab peptric peptide nrog cov qauv nruab nrab
Tshawb Nrhiav thiab Muaj pes tsawg leeg
BPC157 (Lub Cev Tiv Thaiv Cov Compound-157) yog 15-amino acid peptide muab tau los ntawm cov kua txiv cov kua txiv protein BPC. Thaum pib cais nyob rau xyoo 1990, tau pom tias ua kom nrawm nrawm kho cov pa roj carrotric hauv nas, ua rau kev tshawb fawb dav rau hauv nws qhov kev cuam tshuam dav.
► Cov txheej txheem ntawm kev ua
BPC157's Regenerative cov khoom yog multifaceted:
Kev Loj Hlob Qhov Tseeb: nws nce vegf, FGF, thiab EGF qhia, txhawb kev ua haujlwm loj angiogenesis thiab nqaij kho.
Fak - paxecin txoj kev: BPC157 activ activ activ activ activ activ activ activ activ activ activ ((Fak), txhawb nqa ntawm tes nplaum thiab tsiv teb tsaws chaw thiab khiav teb chaws.
Anti -} inflammolatory: nws downregulates nf {}} κ} κb, txo qhov mob plab (IBD) thiab qauv mob caj dab.
Neuroproction: BPC157 tiv thaiv tus txha caj qaum raug mob thiab mob stroke los ntawm modulating glutamate thiab oxidative kev ntxhov siab.
Encial daim ntawv thov
Cov plab zom mov: BPC157 Health -}}}}}}}}}} Cov neeg mob mob hauv Crohn's Cov Neeg Mob, Feem ntau hauv lub lis piam.
Orthopedic kev raug mob: nws nrawm nrawm nrawm nrawm thiab txo qhov mob hauv osteoarthritis los ntawm kev txhawb nqa pob txha mos lug ntxiv.
Cov kev mob neurological: Cov kev tshawb fawb tsiaj qhia pom BPC157 yuav txhim kho cov tsos mob hauv Parkinson tus kab mob thiab ntau yam kev sim siab tsis muaj.
Kev tiv thaiv lub siab: nws mitigates lub siab puas tsuaj los ntawm dej cawv lossis hluav taws xob thiab preservia renal ua haujlwm tom qab {} {}} reperfusion raug mob.
► Kev Tshawb Fawb Kev Nyab Xeeb thiab Kev Tshawb Nrhiav
BPC157 tsis yog - kev lom nyob rau hauv cov qauv tsiaj, tsis muaj cov kev tsis zoo ntawm cov koob tshuaj. Txawm li cas los xij, tib neeg cov ntaub ntawv muaj tsawg, thiab nws cov tshuab ntawm kev ua tseem muaj kev nkag siab. Cov koom haum tswj hwm zoo li FDA tsis tau pom zoo nws rau kev siv cov chaw kho mob, txwv nws qhov kev nrhiav tau los tshawb nrhiav chaw.
Kev Tshaj Tawm Kev Tshawb Fawb thiab Cov Peev Xwm Synergistic
Thaum MOTSC, TB500, thiab BPC157 ACT los ntawm cov kev sib txawv, lawv cov kev siv ua ke yuav muab cov txiaj ntsig synergistic:
Cov metabolic thiab regenerative synergy: motorsc tuaj yeem txhim kho cov metabolism hauv TB500 lossis BPC157, txhim kho cov txiaj ntsig los ntawm tus mob ntshav qab zib lossis cov lus rov qab los ntawm kev phais mob rov qab.
Anti -} mob ua ke: {{the antrulation BPC157 Kev coj ua phem rau BPC157 qhov kev cog lus ntawm kev tiv thaiv kab mob tsis zoo xws li IBD.
Neuroprotection: BPC157 cov khoom neuroregenenenathererenateries yuav muaj kev ntxhov siab rau cov kab mob nevodegenerative.
Txawm li cas los xij, kev kho mob kev siv tau ntawm cov kev sib txuas ua ke, uas xav tau kev sib txuas ua ke, raws li kev sib txuas lus peptide thiab kev sib txuas lus rau kev siv tshuaj ib zaug.
Cov Lus Qhia Yav Tom Ntej thiab cov nyom
Lub peev xwm kho tau ntawm cov peptides yog loj heev, tab sis ntau txoj kev cov nyom yuav tsum raug hais tias:
1) Tib neeg tib neeg: Cov kev kawm nyuaj theem II / iii kev tshawb fawb yog qhov tseem ceeb kom paub meej tias kev ua tau zoo thiab kev nyab xeeb hauv ntau haiv neeg.
2) Cov kev cai khiav tawm sai: Peptides muab tau los ntawm tsis yog-}}} Cov kua txiv ntoo, cov kua txiv ntoo) ntsej muag) ntsej muag.
3) Cov Tshuab Xa Khoom: Tsim cov qauv ruaj khov (piv txwv li, qhov ncauj muaj kev hloov pauv) tuaj yeem txhim kho tus neeg mob ua raws li kev txhaj tshuaj.
4) Kev txhawj xeeb zoo: Off {- ntawv lo rau kev ncaws pob thiab anti {{{ove}}}}} Cov tsev kho mob muaj kev phom sij, tsim nyog qhia kev cai.
MOTSC, TB500, thiab BPC157 sawv cev rau cov frontier tshiab hauv Peptide Kho, tso cov kab mob tshiab, cov nqaij mos, thiab neurodegenerative. Thaum cov ntaub ntawv preclinical yog cog lus, lawv txhais lus rau cov kev tshawb fawb xav tau kev cai lij choj, kev nyab xeeb, thiab kev muaj kev sib tw. Raws li kev tshawb fawb tau nce zuj zus, cov peptides yuav rov qab kho cov tshuaj kho dua tshiab, muab kev nyab xeeb dua rau cov kev kho mob ntxiv.