Hauv tshav pob ntawm biomedicine,BPC 157thiabNad +yog ob qho tshuaj yeeb zoo nrog cov haujlwm tshwj xeeb. Lawv ua haujlwm ua ke dhau los ntawm multi - hom phiaj kho thiab lub zog me me ntawm cov ntaub so ntswg, thiab anti- kev tshawb fawb. Cov kev ntsuas hauv qab no yog ua los ntawm peb qhov ntev: molecular mechanism, cov txiaj ntsig kev noj qab haus huv, thiab cov kev tshawb nrhiav kev tshawb fawb.
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Compllyarity ntawm molecular txheej txheem
BPC 157: tus kws kho mob ntawm tes "rau ntau -} hom phiaj kho
BPC 157 yog 15 {- amino -} acid peptide muab los ntawm cov kua txiv plab zom mov. Nws cov tub ntxhais lub cev ntawm kev nqis tes ua kecompasses angiogenesis, anti-inflammatory, thiab kev tiv thaiv ntawm tes.
Angiogenesis:Los ntawm kev ua siab phem ntawm vascular endothelial kev loj hlob qhov tseem ceeb (FAMF), BPF), BPF), BPF), BPF), BPF), BPF), BPF), BPC 157 tuaj yeem txhawb kev tsim cov ntshav tshiab hauv cov ntaub so ntswg tshiab. Piv txwv li, hauv cov qauv tshuaj ntsuab, kev txhaj tshuaj hauv zos tau ua rau muaj 30% ua tsaug rau hauv kev ua haujlwm zoo nkauj, uas tau txhawb nqa tev ntawm tes thiab collagen synthesis.
Anti -} mob thiab tiv thaiv kab mob:BPC 157 tuaj yeem inhibit qhov kev tso tawm pro -}}}}}}}}} Hauv kev sim ntau yam sclerosis qauv, nws tau tswj xyuas t cell muaj nuj nqi, thiab kho cov kev ua haujlwm lub cev muaj zog.
Kev tiv thaiv ntawm tes:BPC 157 tuaj yeem tiv thaiv enzymatic degradation, tswj nws cov kev ua haujlwm roj ntsha thaum haus cawv, yog li kev haus cawv los ntawm kev haus cawv lossis tsis yog}} roj (NSAID). Ib qho ntxiv, nws tuaj yeem txo qis malabsorption hauv cov neeg mob uas muaj cov plab zom mov (SBS) los ntawm qhov siab tshaj plaws ntawm txoj hnyuv, txhawb kev mob plab hnyuv siab.
NAD +: Tus "tseem ceeb Hub" ntawm lub zog metabolism thiab cov noob chiv keeb
NAD + (Nicotinamide Adenine Tinucleotoide) Ua raws li lub luag haujlwm coenzyme thiab plays lub luag haujlwm tseem ceeb hauv kev kho mob cellular, thiab kev hloov chaw.
Lub zog metabolism:NAD + yog cov tseem ceeb tivthaiv ntawm lub cellular txoj saw hlau, hloov cov zaub mov rau hauv ATP los ntawm Redox Reds. Hauv Aerobic kev ua pa, nws koom nrog hauv TrricarboxLic acid ncig thiab mitochondrial ua pa ntxig, tau txais thiab tso cov electrons; Hauv cov metabolic metabolism, nws txhawb nqa kev tsim cov lactic acid thiab cawv.
DNA kho:NAD + tej kev ua raws li lub substrate rau parp (poly adp -}}}}}} kev kho kom haum kom tswj tau cov ruaj khov. Ib qho ntxiv, nws ua kom muaj cov noob qes ntev los ntawm kev tswj hwm cov kev ua si ntawm sirt1 protein, ncua kev ncua ntawm kev laus.
Kev hloov teeb liab:Nad + Koom Nrog Rau Txoj Cai Regulating Crafadian, Tus Kab Mob Tawm Tsam, thiab Neuroprotection. Piv txwv li, hauv cov kab mob muaj kab mob xws li cov kab mob lupus erhematosus, nce NAD + qib tuaj yeem txhim kho Tell muaj nuj nqi thiab txhawb nqa kev tiv thaiv cell.
Molecular lub hauv paus ntawm cov nyhuv synergistic
Cov nyhuv synergistic ntawm BPC 157 thiab NAD + yog tshwm sim ntawm cov qib hauv qab no:
Lub zog muab khoom thiab kho kom zoo:BPC 157 txhawb nqa cov ntaub so ntswg uas yuav tsum muaj lub zog loj npaum li cas. Nad + Zoo Mitochondrial muaj nuj nqi thiab muab kev txhawb nqa ATP rau kev sib tw ntawm tes thiab collagen synthesis. Piv txwv li, hauv kev ua kom nrawm dua, NAD + tuaj yeem ua kom nrawm angiogenesis ntawm pob txha neej qhov chaw, ua tiav cov nyhuv osteeogenic nyhuv ntawm BPC 157.
Anti -} mob thiab tiv thaiv kab mob:BPC 157 inhibits qhov kev tso tawm ntawm pro-}}} {{{{{-}}} {}}}} {}} {}}}}}} {{}} {}} Kev tsis muaj zog syndrome.
Antioxidant kev nyuaj siab:BPC 157 Upregulates Qhov kev qhia Enzymes enzymes (xws li Sod) rau undeviate neuronal kev puas tsuaj tom qab cerebral ischemia; NAD + pab Nadh los txhim kho lub cell qhov tsis kam mus rau oxidative kev ntxhov siab, kev tiv thaiv kev muaj sia nyob ntawm cov hlab ntsha hlab ntsha.
Multi -} seem qhov chaw nthuav dav ntawm cov txiaj ntsig kev noj qab haus huv
Cov Tshuaj Ua Si Ntaus: Ua kom nrawm dua kev kho mob thiab txhim kho kev ua kom ntev
Tendon thiab Ligament Kho: BPC 157 tuaj yeem luv lub sijhawm rov qab rau cov neeg ncaws pob nrog cov txha hniav txiav thiab hom kab mob. Piv txwv li, hauv cov qauv nas ntawm nruab nrab ntawm collateral lignament kev hloov pauv, tshaj tawm hauv BPC 157 ua rau muaj zog hauv Biomechanical (ntau tshaj plaws load, piv rau pawg tswj. Nad + Zoo Mitochondrial muaj nuj nqi los muab lub zog rau cov txheej txheem kho, txuas ntxiv nrawm nrawm dua.
Kev Kho Mob Raug Mob: BPC 157 txhim kho fibroblast kev ua si thiab txhawb nqa cov leeg kua muag kho; NAD + ua haujlwm tau cov ampk txoj kev los txhim kho cov leeg hluav taws xob metabolism thiab txo cov posts - rog qaug zog.
Cov metabolism thiab kev txhim kho kev thev naus laus zis: BPC 157 txhim kho txoj hnyuv uas muaj ntshav nqus, thaum NAD + txhim kho cov khoom noj pa oxygen. Kev sib xyaw ua ke ntawm ob qho tib si tuaj yeem txhim kho kev ua kis las txoj kev ua tau zoo.
Neuroproction: Kho kev puas tsuaj thiab txo cov kab mob sib txawv
Kev raug mob pob txha caj qaum thiab mob stroke: bpc 157 txhawb kev ua haujlwm thiab txhim kho kev ua haujlwm lub cev; NAD + unceviates hippocampal ischemia- Reizodenes Txom Nyem thiab Angiogenesis- kev txhawb nqa cov tshuab. Piv txwv li, nyob rau hauv lub ntiaj teb Cerebral CreatBral qauv, sib xyaw siv ob leeg tuaj yeem nce ntau tus neeg neurons los ntawm 2.5 zaug txo cov oxidative kev tawm tsam cim (MDA).
Neurodegenerative Kab mob: BPC 157 txhua tus qauv hauv Parkinson cov qauv kab mob, thaum NAD Dirt3 los txo cov Mitochondrial fragmentation thiab tiv thaiv dopamininergico neurons.
Anti -}}}} Kev Laus thiab Kev Tswj Xyuas Kab Mob
Daim tawv nqaij thiab Kho Kom Zoo: BPC 157 accelerates zoo kho kom zoo los ntawm kev kub hnyiab thiab raug mob. Nad + txhawb Collagen synthesis thiab txo qhov tsim ntawm wrinkles. Kev sib xyaw ntawm ob qho tib si tuaj yeem thov hauv anti -} kev laus tawv nqaij tu.
Cov mob metabolic syndrome: BPC 157 txhim kho kev ua haujlwm hnyav plab hnyuv ua haujlwm, thiab kev tswj hwm kev pheej hmoo ntawm cov kab mob metabolism xws li cov rog thiab mob ntshav qab zib.
BPCе Kev Kho Mob: BPC 157 Txhua Qhov Boos 157 Txhua Yam Kev Ua Phem, thiab NAD + tswj hwm cov tshuaj lom neeg siv tshuaj rau cov hlwb ib txwm muaj.
Tshawb nrhiav cov zeem muag thiab cov nyom
Muaj peev xwm rau kev tshawb fawb hauv tsev kho mob
Kev mob me me |- Nplog Tib Neeg Cov Kev Tshawb Fawb: Interta- articular txhaj tshuaj Kev txhaj tshuaj ntawm BPC 157 rau kev kho mob cystStitial citystitis tau ua rau cov tsos mob ua tiav rau 10 ntawm 12 tus neeg mob.
NAD + pab txhawb: NMN (Nicotinamide Mononucleotide) lossis NRONICINAMIDIDE RIBSIDE) Raws li NAD - {} {}} kev nyab xeeb xav tau kev nyab xeeb ntxiv.
Kev Kho Mob: Cov nyhuv synapor ntawm BPC 157 thiab NAD + yog muaj txiaj ntsig hauv cov qauv tsiaj, thiab kev tswj hwm kev sib txuas, cov neurodegenerative tuaj yeem tshawb nrhiav yav tom ntej.
Kev Tshawb Nrhiav Kev Tshawb Nrhiav thiab Cov Lus Qhia
Cov ntaub ntawv tsis txaus ntseeg tib neeg: Tam sim no, kev tshawb fawb tshaj plaws ntawm BPC 157 yog txwv rau kev sim tsiaj. Loj -} teev cov kev sim kho mob xav tau los txheeb xyuas nws txoj kev ua tau zoo thiab kev nyab xeeb.
Txo cov tshuab: kev txheeb xyuas ntxiv yuav tsum kom nkag siab txog cov molecular kev sib cuam tshuam ntawm BPC 157 thiab NAD +. cuam tshuam kev txhim kho ntawm BPC 157 los ntawm kev tswj hwm sirt1.
Ntev -} Kev Ntsuam Xyuas Kev Nyab Xeeb Kev Nyab Xeeb: Qhov tshwm sim ntawm BPC 157 (xws li tsis xis nyob ntawm qhov chaw txhaj tshuaj) yuav tsum tau saib xyuas lub sijhawm ntev; Qhov cuam tshuam ntawm nad + pab ntawm cov metabolism tseem yuav tsum tau nyob hauv - qhov tob tshawb.
Kev Coj Zoo thiab Kev Txiav Txim Siab
Kev tshawb fawb kev txwv: Feem ntau cov tebchaws tsuas pub BPC 157 rau kev tshawb fawb. Cov neeg ncaws pob yuav tsum paub txog anti - doping cov cai.
FDA Cov Txheej Txheem Pom Zoo: BPC 157 tseem tsis tau pom zoo los ntawm FDA. Nws cov ntawv thov kev kho mob yuav tsum ua raws cov txheej txheem nruj med.
Tag
Cov nyhuv synergistic ntawm BPC 157 thiab NAD + muab ib qho paradigm tshiab rau kev tshawb fawb biomedical. Cov kev txhawb nqa yav dhau los cov ntaub so ntswg los ntawm ntau- lub hom phiaj kho kev kho tshuab, thaum lub tom kawg tswj hwm ntawm cov kev cai metabolism hauv hluav taws xob. Ob qho tib si muaj kev cia siab rau cov tshuaj kis las hauv kev ua kis las, neuroprotection, thiab anti - kev laus teb. Txawm li cas los xij, nws cov kev tshawb fawb soj ntsuam tseem yuav tsum tau kov yeej cov teeb meem tseem ceeb xws li cov ntaub ntawv tsub zuj zuj, thiab kev ntsuas kev nyab xeeb. Yav tom ntej, nrog kev tshawb fawb ntxiv, kev sib sau ua ke ntawm BPC 157 thiab NAD + yuav tsum los ua ib lub tswv yim tseem ceeb rau kev txhim kho tib neeg kev noj qab haus huv.