Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm pentagastrin txhaj tshuaj hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo siab pentagastrin txhaj rau muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Raws li cov khoom siv hluavtaws peptide,pentagastrin txhaj tshuajNws muaj peb lub luag haujlwm tseem ceeb: kev tswj hwm endocrine, qog muaj feem cuam tshuam rau kev tshawb nrhiav, thiab ectopic mucosal imaging. Peb lub luag haujlwm no muaj kev ywj pheej ntawm ib leeg thiab muaj lawv tus kheej daim ntawv thov kev kho mob, ua ke tsim nws cov ntawv thov tseem ceeb. Cov hauv qab no muab cov ncauj lus kom ntxaws ntawm peb txoj haujlwm no los ntawm ntau qhov kev xav.
Khoom Description
Pentagastrin COA
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| Certificate of Analysis | ||
| Compound npe | Pentagastrin | |
| Qib | Pharmaceutical qib | |
| CAS Nr. | 5534-95-2 | |
| Ntau | 36g | |
| Ntim txheem | PE hnab + Al foil hnab | |
| Chaw tsim tshuaj paus | Shaanxi BLOOM TECH Co., Ltd | |
| Ntau No. | 202501090097 | |
| MFG | Peb 9, 2026 | |
| EXP | Peb 8, 2029 | |
| Qauv |
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| Yam khoom | Enterprise txheem | Kev txheeb xyuas qhov tshwm sim |
| Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov | Ua raws |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 5.0% | 0.54% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.42% |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 0.5ppm | N.D. |
| Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Hg Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Cd Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Purity (HPLC) | Ntau dua lossis sib npaug li 99.0% | 99.98% |
| Ib qho impurity | <0.8% | 0.52% |
| Tag nrho microbial suav | Tsawg dua lossis sib npaug li 750cfu / g | 95 |
| E. Coli | Tsawg dua lossis sib npaug li 2MPN / g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (los ntawm GC) | Tsawg dua lossis sib npaug li 5000ppm | 500ppm ua |
| Cia | Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab -20 degree | |
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| Tshuaj Formula | C37H49N7O9S | |
| Exact Mass | 767.33 | |
| Molecular Luj | 767.90 | |
| m/z | 767.33 (100.0%), 768.33 (40.0%), 769.34 (5.1%), 769.33 (4.5%), 769.34 (2.7%), 769.34 (1.8%), 768.33 (1.8%), 770.33 (1.8%) | |
| Elemental Analysis | C, 57.87; H, 6.43; N, 12.77; O, 18.75; S, 4.18 | |
Multidimensional yam ntxwv ntawm endocrine activation
Cov nyhuv ntawm endocrine activation ntawmpentagastrin txhaj tshuajmuaj lub hom phiaj meej thiab qhov tshwj xeeb, thiab nws cov ntsiab lus yog los txhawb kev tso tawm cov tshuaj hormones los ntawm kev tswj hwm kev ua haujlwm ntawm lub hom phiaj. Qhov no tuaj yeem txheeb xyuas los ntawm peb qhov loj me:
Kev qhia txawv ntawm histamine thiab serotonin tso tawm
Muaj ib qho kev xaiv tseem ceeb hauv qhov induction thiab tso tawm ntawm histamine thiab serotonin. Kev tso tawm histamine feem ntau tshwm sim sai tom qab kev tswj hwm, uas qhia tau tias muaj txiaj ntsig sai thiab poob sai sai tom qab ncav cuag nws lub ncov, thaum serotonin tso tawm qhia tau hais tias qeeb qeeb thiab poob qis, nrog lub ncov tshwm sim tom qab histamine, thiab qhov tso tawm ntau npaum li cas ntawm ob yog cuam tshuam rau txoj kev tswj hwm. Cov qauv kev tso tawm sib txawv no zoo sib xws rau lawv cov luag haujlwm sib txawv hauv kev tswj hwm lub cev ntawm lub cev thiab muab lub ntsiab lus nkag tshwj xeeb rau kev kawm txog cov txheej txheem physiological cuam tshuam.
Cov koob tshuaj -nyob ntawm cov yam ntxwv ntawm calcitonin tso tawm
Kev ua tau zoo ntawm kev ua kom muaj kev tso tawm ntawm calcitonin los ntawm cov thyroid C hlwb qhia pom tseeb koob - nyob ntawm kev sib raug zoo. Kev siv tshuaj tsawg tsawg tsuas tuaj yeem ua rau me me ntawm calcitonin tso tawm. Thaum cov koob tshuaj nce mus txog qhov pib, tus nqi ntawm calcitonin tso tawm nce ib kauj ruam zuj zus, thiab lub sijhawm tso tawm tseem nyob ruaj khov nyob rau hauv ib qho tshwj xeeb, uas txawv heev ntawm lub cev basal tso tawm suab ntawm calcitonin. Qhov koob tshuaj no-dependent feature muab kev txhawb nqa tseem ceeb rau kev tswj xyuas qhov tseeb, thiab cov txiaj ntsig no tuaj yeem koom nrog kev tswj tsis ncaj ntawm postprandial calcium homeostasis.
Kev kho kom haum xeeb tshwj xeeb ntawm txoj kev tswj hwm
Nws cov txiaj ntsig ua kom endocrine nyob ntawm receptor dependent signaling pathways, uas tshwj xeeb khi rau cov receptors sib raug zoo ntawm lub hom phiaj hlwb, pib intracellular signaling cascades, thiab induce tso tawm cov tshuaj hormones. Cov txheej txheem no tsis tso siab rau kev koom tes ntawm lwm yam kev tswj hwm exogenous thiab muaj lub hom phiaj siab xaiv, tsuas yog tsom rau cov thyroid C hlwb thiab histamine thiab serotonin secretion ntsig txog hlwb, tsis cuam tshuam nrog kev ua haujlwm ntawm lwm cov endocrine hlwb.
Qhov chaw ntawm cov ntaub ntawv:
Emine Kartal Baykan, Mehmet Erdogan. Basal thiab pentagastrin- txhawb nqa calcitonin txiav- tawm qhov tseem ceeb hauv kev kuaj mob ua ntej medullary thyroid cancer. Turkish Journal of Medical Sciences, 2021, 51: 650-656.
Li Juan, Wang Hao Kawm txog kev tswj xyuas cov txiaj ntsig ntawm pentagastrin ntawm kev tso tawm ntawm calcitonin los ntawm cov thyroid C cells Suav Phau Ntawv Qhia Txog Kev Tshawb Fawb, 2021, 25 (3): 412-415
Kev soj ntsuam kev ua tau zoo ntawm pentagastrin stimulation test
Covpentagastrin txhaj tshuajstimulation test tau dhau los ua cov cuab yeej tseem ceeb rau kev kuaj mob qog nqaij hlav thiab kev saib xyuas tom qab phais vim nws qhov tshwj xeeb stimulation nyhuv. Nws qhov kev ua tau zoo tuaj yeem txheeb xyuas los ntawm plaub qhov loj: kev sim tshuab, cov yam ntxwv ntawm kev ua haujlwm, kev tshawb pom qhov zoo, thiab kev saib xyuas tus nqi.
Lub core triggering mechanism ntawm kev sim.
Lub hauv paus ntsiab lus tseem ceeb ntawm qhov kev sim stimulation no yog tias pentapeptide gastric secretin tuaj yeem ua kom lub cev tso tawm ntawm cov thyroid C hlwb.
Txawm tias thaum ntxov lossis occult kab mob tuaj yeem raug ntxias kom tso tawm cov calcitonin txaus, yog li tawg los ntawm cov kev txwv ntawm basal xeev calcitonin nrhiav kom pom thiab nthuav tawm qhov txawv txav ntawm cov kab mob, muab cov teeb liab pom tseeb rau kev kuaj pom qhov txhab.
Cov nodes tseem ceeb ntawm kev sim ua haujlwm.
Kev ua raws li qhov kev sim yuav tsum ua raws li cov txheej txheem kev khiav hauj lwm nruj, thiab txoj kev tswj hwm feem ntau yog txhaj rau hauv cov hlab ntsha. Cov koob tshuaj yog tswj nyob rau hauv ib qho kev nyab xeeb tshwj xeeb, thiab cov ntshav coj mus kuaj ntshav tau raug teeb tsa ntawm 2-5 feeb thiab 30 feeb tom qab tswj hwm. Los ntawm kev kuaj ntshav ntawm ntau lub sijhawm cov ntsiab lus, kev tshawb pom qhov yuam kev tuaj yeem txo qis kom ntseeg tau tias muaj kev ntseeg siab thiab rov ua dua ntawm cov txiaj ntsig kev sim. Nyob rau tib lub sijhawm, nws yuav tsum tau nqa tawm ntawm lub plab khoob kom tsis txhob cuam tshuam los ntawm kev noj haus ntawm cov tshuaj hormones tso tawm.
Kev tshawb nrhiav kom zoo dua ntawm thaum ntxov / zais MTC.
Piv nrog rau kev sim calcitonin hauv paus, qhov kev sim no tuaj yeem txhim kho qhov kev tshawb pom ntawm MTC thaum ntxov thiab occult, tshwj xeeb tshaj yog rau cov neeg mob uas cov qib calcitonin yog qhov tseem ceeb. Nws tuaj yeem paub qhov txawv ntawm benign hyperplasia los ntawm cov kab mob malignant, txo qhov kev kuaj mob ploj mus, thiab nws qhov kev kuaj pom muaj txiaj ntsig zoo dua li lwm txoj hauv kev sim, muab kev txhawb nqa tseem ceeb rau kev cuam tshuam ntxov ntawm MTC.
Kev saib xyuas tus nqi ntawm kev rov ua haujlwm tom qab rov ua haujlwm tom qab- nce.
Hauv kev saib xyuas ntawm kev rov ua haujlwm tom qab rov ua haujlwm hauv MTC, qhov kev sim no tuaj yeem ua haujlwm raws li cov cuab yeej ntsuas tseem ceeb. Yog tias qhov kev ntsuam xyuas tom qab ua haujlwm tseem tuaj yeem ua rau muaj kev nce ntxiv hauv calcitonin, nws qhia tau tias muaj cov qog nqaij hlav los yog rov tshwm sim dua, thiab qhov loj ntawm calcitonin nce siab yog qhov cuam tshuam zoo nrog lub nra hnyav; Yog tias qhov kev kuaj mob tom qab phais tsis tuaj yeem ua rau muaj kev nce ntxiv hauv calcitonin thiab cov theem pib calcitonin nyob rau hauv qhov ib txwm muaj, nws qhia tau tias qhov kev phais phais tau zoo dua. Nyob rau tib lub sijhawm, qhov kev ua tau zoo ntawm kev phais thiab kev pheej hmoo rov qab tuaj yeem raug tshuaj xyuas los ntawm cov txiaj ntsig ntawm qhov sib txawv ntawm lub sijhawm tom qab kev phais.
Qhov chaw ntawm cov ntaub ntawv:
Pasquali D, et al. Prognostic tus nqi ntawm thaum ntxov postoperative calcitonin theem nyob rau hauv medullary thyroid carcinoma. Phau ntawv Journal of Endocrinological Investigation, 1994, 17(4): 301-305.
Labor Nordlab. Calcitonin-Testimulationstest (Pentagastrin-Test). Nordlab Cov Lus Qhia, 2020.
Cov yam ntxwv ntawm kev siv tshuaj kho mob nuclear hauv Meckel's diverticulum
Daim ntawv thov ntawm pentagastrin nyob rau hauv cov tshuaj nuclear imaging ntawm Meckel's diverticulum yog tsuas yog ua tiav los ntawm stimulating ectopic gastric mucosa mus nrhiav qhov txhab. Nws cov yam ntxwv ua haujlwm tuaj yeem txheeb xyuas los ntawm plaub qhov ntev: kev ntsuas kev ntsuas, kev ua tau zoo, cov yam ntxwv ua tau zoo, thiab cov xwm txheej siv tau.
Lub ntsiab induction mechanism ntawm kev loj hlob. Nws cov txheej txheem ntawm kev txiav txim hauv kev tshuaj ntsuam xyuas tshuaj nuclear yog txhawm rau txhawm rau txhawm rau ua kom cov ntaub so ntswg ectopic gastric mucosal hauv Merkel diverticulum, txhim kho nws lub peev xwm los txhawb nqa cov isotopes radioactive, thiab tsim cov duab sib txawv ntawm ectopic mucosa thiab ib puag ncig lub plab hnyuv mucosa, yog li ua tiav qhov tseeb hauv cheeb tsam ntawm cov kab mob. Cov nyhuv induction no muaj cov ntaub so ntswg tshwj xeeb thiab tsuas yog ua haujlwm ntawm ectopic gastric mucosa.
Technical adaptability ntawm nuclide duab. Cov txheej txheem imaging yuav tsum tau siv cov technetium-99m sau npe imaging agent.Tom qab kev tswj hwm ntawmpentagastrin txhaj tshuaj, kev soj ntsuam dynamic yog ua los ntawm kev siv lub tshuab ntsuas hluav taws xob.Cov duab ntawm ectopic gastric mucosa feem ntau tshwm sim nyob rau lub sijhawm tshwj xeeb tom qab kev tswj hwm, thiab qhov kev siv tshuaj ntsuam xyuas tau zoo cuam tshuam nrog thaj tsam thiab kev ua ntawm ectopic mucosa. Nws tuaj yeem nthuav qhia meej txog morphology, qhov loj me, thiab qhov chaw ntawm ectopic mucosa, muab cov ntaub ntawv pov thawj intuitive rau kev kuaj mob.
Qhov tshwj xeeb zoo ntawm kev txhim kho efficiency.Piv rau cov kev siv tshuaj pleev ib ce, cov txheej txheem imaging no muaj ntau dua qhov tshwj xeeb thiab rhiab heev, tshwj xeeb tshaj yog rau occult Meckel's diverticulum.Nws tuaj yeem pab tau zoo rau cov kev txwv ntawm endoscopy thiab cov pa CT kuaj, txo qhov tshwm sim ntawm kev kuaj tsis tau, thiab yooj yim rau kev khiav lag luam thiab cov neeg mob tsawg heev. leej twg intolerant mus kuaj endoscopic.Tim hom ntawv thov scenarios.
Txoj kev ntsuas no yog qhov tsim nyog rau cov neeg mob uas muaj kev ntseeg siab ntawm Meckel's diverticulum hauv kev kho mob tab sis tsis muaj qhov pom tseeb ntawm kev kuaj mob niaj hnub, tshwj xeeb tshaj yog rau cov neeg mob uas tsis tau piav qhia txog kev mob plab hnyuv thiab mob plab. Nws tuaj yeem siv los qhia meej qhov chaw ntawm qhov txhab thiab muab lub hauv paus tseeb rau kev txhim kho kev kuaj mob thiab kev npaj kho mob. Nws kuj tseem siv tau rau kev soj ntsuam kev ua haujlwm tom qab ntawm Meckel's diverticulum.
Qhov chaw ntawm cov ntaub ntawv:
Gagel RF, thiab al. Kev sib piv ntawm Ob Qhov Kev Ntsuas Kev Ntsuas rau Calcitonin hauv Medullary Thyroid Carcinoma: Omeprazole vs Pentagastrin. Clinical Chemistry, 2002, 48(9): 1505-1511.
Cov ntaub ntawv
Salvador Treves, Richard J. Grand, Angelo J. Eraklis. Pentagastrin Stimulation of Technetium-99m Uptake los ntawm Ectopic Gastric Muscosa hauv Meckel's Diverticulum. Radiology, 1978, 128(3): 711-714.
Lub Koom Haum ntawm Nuclear Tshuaj thiab Molecular Imaging. Cov Txheej Txheem Qhia Txog Kab Mob Ntshav Qab Zib thiab Meckel's Diverticulum Scintigraphy. Phau ntawv Journal of Nuclear Medicine, 2009, 40(7): 1226-1236.
Persson B, Lulhman C. Studies on Pentagastrin-Induced Hypocalcemia in Lactating Cows. Acta Veterinaria Scandinavica, 1976, 17(2): 127-136.
A. Izzat, NG Waton. Tso tawm 5-Hydroxytryptamine los ntawm Pentagastrin thiab Nws Lub Luag Haujlwm hauv 'Fade' ntawm Stimulated Gastric Secretion hauv Miv. Phau ntawv Journal of Physiology, 1978, 283(3): 491-502.
FAQ
Pentagastrin siv rau dab tsi?
Pentagastrin yog ib qho gastrin-zoo li molecule siv los ua kev kuaj mob rau kev soj ntsuam ntawm gastric acid secretory function, gastric hypersecretion, thiab Zollinger-Ellison qog. Ib tug hluavtaws pentapeptide uas ua raws li cov kev ua ntawm endogenous gastrin thaum muab parenterally.
Dab tsi yog pentagastrin stimulation test?
Lub hom phiaj ntawm qhov kev sim no yog los pab peb paub seb puas muaj cov tshuaj calcitonin ntau dhau los ntawm koj cov thyroid caj pas. Kev tsim cov tshuaj calcitonin ntau dhau yuav qhia tau tias muaj qee yam qog nqaij hlav qog noj ntshav tsawg. Kev npaj rau koj qhov kev xeem.
Cim npe nrov: pentagastrin txhaj tshuaj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom