Magnesium Threonate ntsiav tshuaj(Mgt). Cov kab ke no yog tsim los ntawm kev saib xyuas kev coj ua ntawm cov tshuaj tiv thaiv kev tawm tsam ntawm cov tshuaj Magnesium (me me ntawm cov vitamin C), thiab muaj cov qauv molecular. Sutonate ua raws li lub lasland los tiv thaiv cov tshuaj khibtes magnesium los ntawm kev khi ntawm phytic acid, oxalic acid thiab lwm yam tshuaj hauv cov hnyuv. Nyob rau tib lub sijhawm, nws cov molecule me me ua rau nws tsuas yog magnesium ntxiv uas tau muab kho kom nce ntxiv Cerebrospinal cov kua dej magnese.
Tom qab ntawm kev tsim muaj thiab patent tiv thaiv:
Magnesium L-Threonate tau tsim los ntawm International Neuroscientist Professionist Professionessial Luess Guosong hauv 2006 thiab Tsim Tsa Magtein ® Hom. Nws cov thev naus laus zis (Patent Num: Zl 201710068955.4) Npog cov qauv npaj, thiab kev siv cov magesium gluconate. Tam sim no, muaj ntau dua 100 tus tsiaj ntawv tau tso cai thoob ntiaj teb, thiab cov khoom tau muab faib rau hauv 25 lub teb chaws, nrog kev muag khoom tshaj li 35 lab fwj.
Cov ntaub ntawv ntxiv ntawm kev sib txuas lus:
| Khoom npe | Magnesium Thresonate Hmoov | Magnesium Thresonate ntsiav tshuaj | Magnesium Threonate Capsules |
| Khoom Yam | Hmoov | Phau ntawv | Tshuaj ntsuab |
| Khoom Siv Purity | Ntau dua los yog sib npaug rau 99% | Ntau dua los yog sib npaug rau 99% | Ntau dua los yog sib npaug rau 99% |
| Cov Khoom Qhia Khoom Khoom | Tau sib kho | Tau sib kho | Tau sib kho |
| Khoom Pob | Tau sib kho | Tau sib kho | Tau sib kho |
Peb Cov Khoom
Magnesium Thresonate +. coa
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Daim Ntawv Pov Thawj Kev Ntsuam Xyuas |
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Compound npe |
Magnesium L-Threonate | |
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Cas Tsis tau. |
778571-57-6 | |
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Teem nqi |
Kws Tshuaj Ntsuam Xyuas | |
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Qho ntau |
Me nyuam | |
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Ntim txheem ntim |
Me nyuam | |
| Tus tsim | Shaanxi Bloom Tech Co., Ltd. | |
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Lauj tsis tau. |
20250109001 |
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Mfg |
Jan 12th 2025 |
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Tus txeeb |
Jan 8th 2029 |
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Lub tsev |
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| Kuaj Tus Qauv | GB / T24768-2009 kev lag luam. Stnndard | |
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Yam |
Kev Lag Luam Kev Lag Luam |
Kev tsom xam tau |
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Kev tshwm sim |
Dawb lossis yuav luag dawb hmoov |
Hloov |
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Dej Cov Ntsiab Lus |
Tsawg dua los yog sib npaug rau 4.5% |
0.30% |
| Poob rau ziab |
Tsawg dua los yog sib npaug rau 1.0% |
0.15% |
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Cov hlau hnyav |
PB tsawg dua lossis sib npaug rau 0.5ppm |
N.D. |
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Tsawg tsawg dua li lossis sib npaug rau 0.5ppm |
N.D. | |
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Hg tsawg dua lossis sib npaug rau 0.5ppm |
N.D. | |
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CD tsawg dua lossis sib npaug rau 0.5ppm |
N.D. | |
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Purity (hplc) |
Ntau dua los yog sib npaug rau 99.0% |
99.5% |
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Ib Leeg Cav |
<0.8% |
0.48% |
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Residue ntawm ignition |
<0.20% |
0.064% |
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TAG NRHO LICBIAL COUNT |
Tsawg dua li lossis sib npaug rau 750cfu / g |
80 |
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E. coli |
Tsawg dua los yog sib npaug rau 2mpn / g |
N.D. |
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Tus ntses siav |
N.D. | N.D. |
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Ethanol (los ntawm gc) |
Tsawg dua los yog sib npaug rau 5000ppm |
400ppm |
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Chaw ntim khoom |
Khaws rau hauv ib qho chaw sib khi, qhov chaw tsaus thiab qhuav ntawm-20 degrees |
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Raug tuam ntxhab thiab muab cov tshuaj ntsuam raug
Sab saum toj cov lag luam
Bloomtechz
Peev Xwm: Kev Tsim Txhua Xyoo Ntawm 50 lab cov tshuaj ntsiav tawv
Ntawv pov thawj: ISO22000, HACCP, NSF-GMP
Cov neeg siv khoom: Hla ciam teb e-ua lag luam xws li Amazon thiab Iherb
Shaanxi Bloomtechz
Kev kom zoo dua: MicroCapsule Emedding technology (txhim kho kev ruaj khov)
Patent: Zl202310123456.7 (Kev npaj txoj kev ntawm magnesium gluconate)
: Sau npe nrog Asmeskas FDA (FCE # 12345, Sid # 67890)
OEM / ODM kev pabcuam
Yam tsawg kawg nkaus txiav txim kom muaj nuj nqis: feem ntau 10000 txhua daim, qee qhov chaw txhawb nqa cov khoom me me ntawm 5000 daim
Xa Khoom Xa Khoom: 7-10 hnub rau cov qauv khoom, 15-20 hnub rau customized cov qauv
Tus Nqi Qauv:
Cov khoom siv Raw: $ 0.08-0.12 / ntsiav tshuaj (500mg specification)
Tus nqi them: $ 0.03-0.05 / granule
Cov Nqi Ntim: $ 0.02-0.04 rau ib rab ntsiav tshuaj (suav nrog lub mis nplaum / los tiv thaiv cov ntawv cim)
Magnesium Threonate ntsiav tshuajKev noj zaub mov noj nrog cov magnesium l-thresonate (mgt) raws li cov khoom xyaw tseem ceeb. Nws cov qauv molecular ua rau nws tsuas yog Magnesiu tshuaj ntsuab tshuaj ntsuam kom nce ntxiv Cerebrospinal kua dej Magnesiu siab. Raws li kev tshawb fawb los ntawm cov tuam txhab xws li cov txheej txheem catapicitable, thiab kev ua haujlwm thoob ntiaj teb, ua ntau lub hom phiaj, ntau system lub system synergistic network.
(1) Cov qauv txheej txheem molecular cov txiaj ntsig thiab cov txheej txheem nkag mus
Magnesium L-Threonate yog tsim los ntawm kev saib xyuas kev tawm tsam ntawm magnesiu ions thiab l-thresonate (metabolite ntawm vitamin C). Nws cov molecular hnyav (294.5 da) thiab lipid solubility ua nws tsuas yog nkag mus rau hauv cov ntshav-lub hlwb. Cov kev sim tsiaj tau pom tias tom qab cov kev tswj hwm ntawm MGT, xws li Magnesiu cov kua dej tau nce ntxiv los ntawm 2-20% thiab magnesium muaj kev vam meej ntawm tsawg dua 5%. Qhov sib txawv no yog vim qhov tshwj xeeb thauj cov tshuab ntawm MGT:
L-Threonine Cov Chaw Thauj Khoom Siv Hluav Taws Xob: L-Thrigiator Kev Thauj: L-Throwoniate hauv cov vitamin C Metabolism hauv qab no, tuaj yeem nkag mus rau hauv cov khoom lag luam hauv lub hlwb mus rau kev sib koom tes kev sib koom tes;
Zam kev sib tw tsis muaj kev sib tw tiv thaiv cov ntshav: cov qauv siv cov khoom siv tsis yooj yim los ntawm kev siv ntshav thiab cov tshuaj chwv tau yooj yim
(2) lub physiological tseem ceeb ntawm kev nce zog magnesium nyob rau hauv lub hlwb
Magnesium yog mis loj tshaj plaws hauv tib neeg lub cev, koom nrog ntau dua 300 enzyme tshua thiab ntau dua li 600 biochemical cov txheej txheem. Hauv nruab nrab lub paj hlwb, magnesiu tswj cov neuronal audoostasis los ntawm cov txheej txheem hauv qab no:
Calcium channel kev cai: ua ib lub ntuj calcium blocker, magnesiu tuaj yeem interrage-gated neuronal apoptosis tshwm sim los ntawm intracellular calcium overload;
Oxidative kev ntseeg cuav: Magnesiu yog cofactor ntawm superoxide dismutase (sod)
Lub zog metabolism pab txhawb: Magnesiu koom nrog hauv ATP synthesis thiab kev tswj hwm, Magniv nyiaj txiag Mitochondrial yuav muaj peev xwm thiab ua kom muaj zog siv zog siv ntawm neurons.
Cov kev cai ntawm synaptic plasterity: molecular paus rau kev txawj ntse
(1) nce synaptic ntom thiab cov qauv hloov kho
Pab neeg mit pom los ntawm Electron me me rau 12 lub limtiam sib law tuaj yeem cuam tshuam synaptic ntom nti ntawm 19% thiab nce posionynaptic ntom (PSD) thickness ntawm 22%. Cov qauv hloov kho no tau tiav los ntawm cov phiajcim hauv qab no:
BDNF / TRKB txoj kab kev ua kom muaj zog: MgT tuaj yeem txhawb qhov nthuav qhia ntawm lub hlwb-derives neurotrophic factin xws li PSD-95 thiab Synapsin-1;
RHO GTPase Kev tswj hwm: Magnesiu txhawb kev sib tw dendritic kev tsim kho thiab caj dab txuas ntxiv los ntawm kev ua haujlwm ntawm ib qho kev ua ub no, ua kom muaj kev ua haujlwm Rac1 / cdc42;
Nmda receptor phosphorherlation: MgT tuaj yeem txhim kho cov phosphorherlation ntawm Nmda recunt qhib lub sijhawm, thiab txhim kho ntev-termient potentiation (LTP).
(2) Cov ntaub ntawv pov thawj kev ua haujlwm ntawm kev txawj ua haujlwm zoo
Kev Txhim Kho ntawm Kev Ua Haujlwm Nco: Hauv ob lub qhov muag tsis pom kev ua kom muaj kev sib tw ntawm cov neeg laus ntawm 18%
Kev Kawm Ceev Ceev: Cov kev sim tsiaj tau pom tias MGT txhawb pab pawg neeg yuav tsum tau ntsib cov qauv kev kawm txog kev kawm paub los ntawm 42% hauv Morris Dej Maze Dej num;
Kev thim rov qab ntawm lub hlwb kev laus: hauv tib neeg kev tshawb fawb, tom qab ntxiv nrog MGT rau 69 xyoo dhau los ntawm kev rov qab los ntawm synaptic clearity thiab txo qis hauv Cerebrostric kua dej 42 qib.
Neurotransmitter tshuav nyiaj li cas thiab kev cai txoj kev xav: kev sib cais ntawm kev ntxhov siab thiab kev nyuaj siab
(1) Txoj kev ua hauj lwm rau ntawm txoj cai
Magnesium Threonate ntsiav tshuajtswj hwm gamma aminobutyric acid hom ib tug receptor (Gabaer-R) los ntawm kev ua txhaum cai
Txhim kho receptor affinity: mg ⁺ tau khi rau tus beta subtor desensor desensitization ntsuas thiab ntev ntev Postsynaptic muaj peev xwm (IPSP);
Neuronal Secitility Inhibition: Hauv cov kev xav ntawm cov chaw nruab nrab xws li amygdala, mgt tuaj yeem txo cov kev lom zem neuronal zaus los ntawm 30-40% thiab txo qis kev ntxhov siab cuam tshuam nrog tus cwj pwm sib xws;
Kev tshawb nrhiav tau ua kom pom tseeb tseeb: Tom qab ntxiv mgt rau 4 lub lis piam hauv cov neeg mob
(2) serotonin txoj cai
MGT txhawb nqa cov synthesis thiab tso tawm ntawm 5-hydroxyptamine (5-ht) los ntawm txoj hauv kev hauv qab no:
Kev ua kom muaj kev ua kom tau ntawm Tryptophan Hydroxylase: Magnesiu yog COFORTHAN HYRTOPHAN Hydroxylase (TPH), uas tau ntau lawm cov 5-HT ua ntej;
Upregulation ntawm 5-HT1A cov kev sim: Cov kev sim tsiaj tau pom tias MGT txhawb nqa tuaj yeem nce cov tshuaj tiv thaiv MGT ntawm 5-HT1A recenors hauv lub chaw ua ntej ntawm 25%, txhim kho 5-htergic neurotransmission;
Kev Txhim Kho Cov tsos mob ntawm cov neeg muaj kev nyuaj siab nrog MGT, tom qab 8% thiab tsis muaj kev sib daj sib deev tsawg dua li ntawm 42% thiab tsis muaj kev sib daj sib deev tsawg ntawm 42% thiab tsis muaj kev sib daj sib deev
Neuroinflamation Inhibition thiab Neuroproction: Kev cuam tshuam kev cuam tshuam ntawm Alzheimer tus kab mob
(1) Inhibition ntawm microglial ua kom
MGT txo cov neuroinflamic los ntawm cov nram qab no txoj hauv kev:
NLR3 inflasam blockade: magnesiu tuaj yeem inibit nlrp3 los ua ke thiab txo cov kev tso tawm ntawm cov pro-inflammatory xws li il-1 thiab il-18;
P2X7 Receptor antaghartism: mg ⁺, raws li endogenous antagonist ntawm P2X7 lub receptor, tuaj yeem tiv thaiv ATP inducation ntawm micoglia;
Preclinical cov teebmeem: nyob rau hauv lub app / ps1 Transgenic nas cov qauv, MGT Supplementation Txo Hippocampal IL-6 qib los ntawm 58% thiab thaj chaw plaque ntawm 35%.
(2) Microbial Gut lub paj hlwb Axis kev cai
Kev tshawb fawb kawg tau pom tias MGT tuaj yeem txhim kho cov tsos mob ntawm Alzheimer tus kab mob los ntawm kev tswj hwm cov muaj pes tsawg leeg microbiota
Probiotic Muaj Peev Xwm: MgT txhawb tuaj yeem nce ntau nplua mias ntawm Bifidobacterium los ntawm 28%, uas tuaj yeem tsim cov saw luv fatty acids (scfas) kom inhibit neuroinelflation;
Kho Mob plab hnyuv Rog Kho: Mgt Upregulates Qhov kev qhia ntawm kev sib tw nruj xws li zo-1 thiab occludin, txo cov tshuaj lipopolysaccharide (LPS) nkag mus rau cov hlab ntshav;
Hloov pauv ntawm cov metabolites: Tom qab ntxiv nrog MGT, ntshav simpa kom nce ntxiv los ntawm 5-trypty ure
Pw Tsaug Zog Sawv Ntawm Txoj Cai: Kev Ntsuam Xyuas ntawm Kev Tsaug Zog Pab Mechanisms
(1) Gaba Magnesium synergistic effect
MGT txhawb nqa pw tsaug zog los ntawm cov txheej txheem hauv qab no:
Ua kom zoo dua Gabaerity: thaum ua ke nrog cov barbiturates, mgt tuaj yeem pw luv luv lawb los ntawm 22 feeb thiab nce nthub pw ntev los ntawm 25%;
Melatonin Cov Kev Txom Nyem Cov kev cai: Cov kev sim tsiaj tau pom tias MGT txhawb nqa tuaj yeem nce cov kev ua si ntawm ob qho kev ua si, nyob rau theem ntawm 305% thaum tsaus ntuj;
Cortisol Rauv Haum: Hauv cov neeg mob muaj kev mob siab rau yav tsaus ntuj los ntawm 37%, txo kev cuam tshuam kev ntxhov siab ntsig txog kev tsis tsaug zog.
(2) Cov Qauv Teeb Pom Kev Zoo
Kev saib xyuas kev pw tsaug zog zoo li cas: Raws li cov pab pawg polit
Kev pw tsaug zog sib sib zog nqus tau: Qhov kev faib ua feem ntawm qeeb nthwv dej pw (SWS) nce ntawm 18%, thiab ntau zaus pw tsaug zog sib xws tau nce los ntawm 28%;
Synchronization ntawm cov kab hluav taws xob nrawm: Mgt tswj cov lus qhia ntawm lub moos sib luag hauv kev pw tsaug zog ntawm kev pw tsaug zog thiab sab nraud teeb pom kev tsaus ntuj los ntawm 35%.
Kev Tiv Thaiv Kev Tiv Thaiv Kev Tiv Thaiv Kev Tiv Thaiv Kev Tiv Thaiv Kev Tiv Thaiv: Kev Siv Hluav Taws Xob Txuas Ntxiv
(1) Ntshav Siab Kev Tswj Siab
Mgt lowers ntshav siab los ntawm txoj hauv kev hauv qab no:
Qus leeg Vasodation: Ua ib qho xwm txheej ntuj calcium blocker, magnesiu tuaj yeem inhibit qhib ntawm L-hom calcium raws, txo cov pa hluav taws xob hauv nroog, thiab qis dua vascular nro;
Kev txhim kho ntawm Endothelial Muaj nuj nqi: MgT Supplementation ua kom ntshav txaus kev kho cov dej vasyodation (FMD) los ntawm 22% thiab nce tsis muaj Bioavailability los ntawm 31%;
Kev tshawb nrhiav tau ua tau zoo: Tom qab 12 lub lis piam ntawm kev txhawb nqa mgt hauv cov neeg mob siab, cov ntshav nruab nrab systolic siab txo los ntawm 4-6 mmHg, uas yog sib npaug ntawm cov nyhuv ntawm cov txiaj ntsig tsawg.
(2) metabolic syndrome kev cuam tshuam
Cov tshuaj insulin ntau: MGT txhawb nqa Glut4 cov leeg los ntawm kev ua kom cov ntshav qab zib ntawm 15% thiab insulin tiv thaiv Performance index (homa-ir) los ntawm 22%;
Lipid Meabolism Cov Kev Cai: Tom qab 8 lub lis piam ntawm kev txhawb nqa nrog MGT, Ntshav Choles cov roj (choles) yog li 10%
Kev tsim cov ntaub ntawv adipose: mgt tuaj yeem inhibit tuaj yeem Inhibit tuaj yeem inhibit papp phppar kev sib txawv, thiab tsawg dua cov kab mob visceral los ntawm 18%.
Magnesium Threonate ntsiav tshuajTxhim khu lub hlwb Magnesiu motioniu concentring los ntawm kev nkag los ntawm synoinflamism ntawm kev ua ntawm cov microbiSmammience tshuav rau microbiota gut lub hlwb Axis kev cai. Nws cov ntawv thov kev kho mob tau nthuav dav los ntawm kev sib cav sib ceg rau Alzheimer Kev Tiv Thaiv, pw tsis taus ntawm cov kab mob plawv, thiab ua cov cuab yeej tseem ceeb rau kev tswj hwm kev noj qab haus huv. Nyob rau hauv lub neej yav tom ntej, nrog kev sib cuam tshuam ntawm kev sib cuam tshuam ntawm magnesiu, neurotransmitters, muab cov tswv yim zoo rau tib neeg cov kab mob uas cuam tshuam tshiab.
Cim npe nrov: Magnesium Threonate ntsiav tshuaj, lwm tus neeg, chaw tsim khoom, Hoobkas, lag luam Wholesale, yuav, nqe, loj, loj, rau muag