Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm azithromycin cas 83905-01-5 hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo azithromycin cas 83905-01-5 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Azithromycinyog tshuaj tua kab mob macrolide feem ntau siv los kho ntau yam kab mob. Nws lub ntsiab tivthaiv yog ib qho khoom siv hluav taws xob kaum tsib tus tswvcuab cyclic ester tshuaj tua kab mob, uas zoo nkaus li dawb los yog tawm dawb crystalline hmoov, tsis muaj ntxhiab, iab hauv saj, thiab me ntsis hygroscopic. Nws yog soluble hauv methanol, acetone, anhydrous ethanol, lossis dilute hydrochloric acid, soluble hauv acetonitrile, thiab yuav luag insoluble hauv dej. Nws cuam tshuam nrog cov protein synthesis ntawm cov kab mob rhiab heev los ntawm kev khi rau lawv cov 50s ribosome subunits, yog li inhibiting kab mob loj hlob thiab kev loj hlob. Cov tshuaj tua kab mob ntawm cov tshuaj no zoo ib yam li erythromycin, tab sis nws cov nyhuv ntawm qee cov kab mob xws li Haemophilus influenzae thiab Neisseria gonorrhoeae muaj zog dua erythromycin.
Cov ntaub ntawv ntxiv ntawm chemical compound:
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Tshuaj Formula |
C38H72N2O12 |
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Exact Mass |
748.51 |
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Molecular Luj |
749.00 |
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m/z |
748.51(100.0%),749.51 (41.1%), 750.52 (8.2%), 750.51 (2.5%), 751.52 (1.1%), 751.52 (1.0%) |
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Elemental Analysis |
C, 60.94; H, 9.69; N, 3.74; O, 25.63 |
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Melting point |
113-115 degree |
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Boiling point |
822.1 ± 65.0℃(Predicted) |
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Qhov ntom |
1.18 ± 0.1 g / cm3 (Tshaj tawm) |
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Cia tej yam kev mob |
2-8 degree |
Nws muaj qee yam tshuaj tua kab mob tiv thaiv kab mob Gram zoo, kab mob Gram tsis zoo, thiab qee cov kab mob anaerobic. Nws tuaj yeem kho ntau yam kab mob me me mus rau nruab nrab los ntawm cov kab mob microbial rhiab heev.
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Azithromycinyog tshuaj tua kab mob macrolide, uas muaj cov kab mob dav dav thiab cov yam ntxwv pharmacokinetic. Yog li ntawd, nws yog dav siv nyob rau hauv kev kho mob ntawm ntau yam kab mob nyob rau hauv kev kho mob. Cov hauv qab no yog cov lus piav qhia ntxaws txog nws lub hom phiaj:
antibacterial mechanism
Nws inhibits cov kab mob protein synthesis thiab tsim cov tshuaj tua kab mob los ntawm kev thaiv cov txheej txheem ntawm cov kab mob peptide hloov dua siab tshiab. Nws khi rau cov kab mob 50S ribosomal subunit, tiv thaiv kev txuas ntxiv ntawm peptide saw, ua rau cov kab mob loj hlob thiab tuag. Cov txheej txheem no ua rau azithromycin zoo tiv thaiv ntau yam kab mob Gram zoo, kab mob Gram tsis zoo, kab mob anaerobic, thiab lwm yam kab mob.
qhia
Cov kab mob ua pa thiab kab mob ntawm daim tawv nqaij thiab cov nqaij mos
Nws tuaj yeem siv los kho cov kab mob ua pa sab sauv xws li mob pharyngitis thiab mob tonsillitis tshwm sim los ntawm cov kab mob rhiab heev. Nws cov txiaj ntsig kho mob yog qhov tseem ceeb, thiab noj nws ib zaug ib hnub rau 3 hnub sib law liag tuaj yeem ua tiav cov txiaj ntsig kho mob ntawm kev noj lwm cov tshuaj tua kab mob rau 7-10 hnub. Nws muaj kev ua tau zoo thiab tshwj xeeb tshaj yog rau cov menyuam yaus. Nws yog ib qho tshuaj siv los kho cov kab mob ua pa qis xws li mob ntsws ntsws thiab mob ntsws.
Nws muaj kev ua haujlwm zoo tiv thaiv kab mob ua pa xws li Streptococcus pneumoniae, thiab tshwj xeeb tshaj yog haum rau kev kho mob hauv zej zog- kis mob ntsws. Tsis tas li ntawd, azithromycin feem ntau yog siv los kho cov kab mob ua pa qis hauv cov menyuam yaus uas muaj mycoplasma, chlamydia, lossis beta lactam resistant bacteria. Nws tau pom tias muaj txiaj ntsig zoo tiv thaiv cov kab mob ntawm daim tawv nqaij xws li Staphylococcus epidermidis thiab tuaj yeem siv los kho cov tawv nqaij thiab cov nqaij mos xws li cellulitis thiab pustules.
Kab mob sib deev & lwm yam kab mob
Azithromycin yog ib hom tshuaj uas nquag siv los kho cov kab mob sib deev xws li kab mob ntawm qhov chaw mos uas yooj yim los ntawm Chlamydia trachomatis thiab tsis yog gonococcal urethritis. Nws txoj kev kho ib zaug yog yooj yim heev thiab siv tau zoo hauv kev kho cov kab mob no. Nws kuj tseem siv tau los kho cov kab mob xws li mob otitis media thiab sinusitis. Azithromycin kuj tseem muaj qee qhov txiaj ntsig rau kev tiv thaiv qee yam kab mob, tshwj xeeb tshaj yog rau cov neeg mob uas muaj lub cev tsis muaj zog.
Kev siv hauv Otorhinolaryngological Infections (Nqa Otitis Media ua piv txwv)
Azithromycin yog ib hom tshuaj uas nquag siv rau kev kho cov kab mob ntawm cov kab mob otorhinolaryngological, nrog rau kev ua tau zoo ntawm kev tswj cov kab mob otitis media, tshwj xeeb tshaj yog rau cov mob suppurative otitis media hauv cov menyuam yaus thiab cov neeg laus. Mob otitis media feem ntau yog tshwm sim los ntawm kev kis tus kab mob xws liStreptococcus pneumoniaethiabHemophilus influenzae. Azithromycin siv nws cov tshuaj tua kab mob los ntawm inhibiting cov kab mob protein synthesis, thiab nws tuaj yeem nkag mus rau hauv nruab nrab pob ntseg mucosa kom ncav cuag cov kev kho mob zoo nyob rau hauv nruab nrab pob ntseg kab noj hniav, sai sai tshem tawm cov tsos mob xws li mob pob ntseg, aural fullness thiab otorrhea.
Hauv kev xyaum kho mob, cov qauv ntawm qhov ncauj tsim nyog rau cov neeg laus thiab cov menyuam yaus lub cev hnyav dua lossis sib npaug li 45 kg, suav nrog kev kho mob luv luv thiab ua raws cov neeg mob siab; koob tshuaj rau menyuam yaus yuav tsum tau kho raws li lub cev hnyav kom tsis txhob siv ntau dhau. Tsis tas li ntawd, azithromycin tuaj yeem siv los ua kev kho mob ntxiv rau lwm cov kab mob otorhinolaryngological. Piv txwv li, nyob rau hauv cov xwm txheej nyuaj nrog sinusitis los yog pharyngitis, nws dav - spectrum antibacterial nyhuv tuaj yeem npog cov kab mob pathogenic, txo qhov kev pheej hmoo ntawm kev kis kab mob thiab txhim kho cov txiaj ntsig kev kho mob.
Kev siv rau hauv enteritis thiab dysentery
Azithromycin muaj cov nyhuv inhibitory ntawm ntau yam kab mob hauv plab hnyuv thiab tuaj yeem siv los kho cov kab mob enteritis thiab kab mob plab los ntawm cov kab mob uas raug cuam tshuam, tshwj xeeb tshaj yog rau cov kab mob enteritis thiab bacillary dysentery. Enteritis thiab dysentery feem ntau yog tshwm sim los ntawm kev kis kab mob nrog cov kab mob xws liShigella, SalmonellathiabEscherichia coli, nrog rau kev kho mob tshwm sim nrog rau mob plab, raws plab, thiab mucopurulent thiab ntshav quav. Azithromycin tuaj yeem xaiv inhibit qhov kev loj hlob ntawm cov kab mob zoo li no thiab thaiv kev kis kab mob. Piv nrog rau lwm cov tshuaj tua kab mob, azithromycin yog nqus sai sai tom qab kev tswj hwm qhov ncauj thiab tuaj yeem tswj tau cov tshuaj siab hauv cov hnyuv mucosa, ua ncaj qha rau ntawm qhov chaw muaj kab mob nrog qhov pib sai.
Hauv kev siv tshuaj kho mob, chav kho mob yuav tsum tau hloov kho raws li qhov hnyav ntawm tus kab mob: 3-5 hnub rau cov kab mob me me, thiab tsim nyog ntev rau kev kis mob hnyav. Lub caij no, cov tshuaj yuav tsum tau kho kom haum rau kev txhim kho cov neeg mob cov tsos mob kom tsis txhob siv qhov muag tsis pom. Nws yuav tsum raug sau tseg tias azithromycin tsis muaj txiaj ntsig rau tus kab mob enteritis, thiab cov tshuaj muaj txiaj ntsig yuav tsum tau muab tshuaj tom qab kuaj pom tseeb ntawm etiology.
Kev phiv tshuaj
Azithromycinyog tshuaj tua kab mob macrolide, uas yog siv dav hauv kev kho mob ntawm ntau yam kab mob. Txawm li cas los xij, zoo li lwm yam tshuaj, azithromycin kuj tseem tuaj yeem ua rau muaj kev cuam tshuam tsis zoo thaum siv. Cov hauv qab no yuav piav qhia txog nws cov kev phiv tsis zoo, suav nrog lawv hom, cov txheej txheem ntawm qhov tshwm sim, qhov tshwm sim ntawm kev kho mob, kev kho mob, thiab kev tiv thaiv kev tiv thaiv:
Hom kev phiv tshuaj
Kev tsis zoo tshwm sim hauv plab hnyuv
Cov tsos mob: xeev siab, ntuav, mob plab, raws plab, plab zom mov, plab hnyuv plab, thiab lwm yam.
Mechanism ntawm qhov tshwm sim: Azithromycin tuaj yeem cuam tshuam kev loj hlob ntawm cov plab hnyuv microbiota, ua rau muaj qhov tsis txaus ntawm plab microbiota thiab tom qab ntawd ua rau cov tsos mob plab. Tsis tas li ntawd, azithromycin kuj tseem tuaj yeem ua rau mob plab hnyuv thiab ua rau lub plab tsis zoo.
Qhov tshwm sim: Cov tshuaj tiv thaiv kab mob plab yog qhov tshwm sim tsis zoo tshaj plaws ntawm azithromycin, nrog rau qhov tshwm sim ntau heev.
Kev tsis haum tshuaj
Cov tsos mob: tawm pob, khaus, urticaria, photosensitivity, angioedema, bronchospasm, anaphylactic shock, thiab lwm yam.
Mechanism ntawm qhov tshwm sim: Azithromycin belongs rau cov chav kawm tshuaj tua kab mob macrolide, thiab nws cov qauv molecular zoo ib yam li cov tshuaj tiv thaiv uas tsim los ntawm tib neeg lub cev tiv thaiv kab mob, uas tuaj yeem ua rau muaj kev tsis haum tshuaj.
Qhov hnyav: Kev tsis haum tshuaj tuaj yeem mob me lossis hnyav, thiab qhov mob hnyav tuaj yeem ua rau muaj sia nyob - hem.
Neurological tsis zoo tshwm sim
Cov tsos mob: kiv taub hau, mob taub hau, tsaug zog, vertigo, convulsions, hyperkinesia, qeeb teb, kev xav ntxhov siab, thiab lwm yam.
Mechanism ntawm qhov tshwm sim: Azithromycin tuaj yeem ua rau cov tsos mob ntawm lub paj hlwb los ntawm kev cuam tshuam kev sib kis ntawm neurotransmitters lossis cuam tshuam nrog kev ua haujlwm ntawm lub paj hlwb.
Kev tshwm sim: Cov kev tsis zoo ntawm lub paj hlwb yog qhov tsawg ntawm cov neeg siv azithromycin, tab sis thaum lawv tshwm sim, lawv yuav muaj kev cuam tshuam loj rau tus neeg mob lub neej zoo.
Cardiovascular system phiv tshuaj
Cov tsos mob: palpitations, mob hauv siab, hypotension, thiab ntsis twisting ventricular tachycardia.
Mechanism ntawm qhov tshwm sim: Cov tshuaj no tuaj yeem ncua sijhawm QT thiab ua rau muaj kev pheej hmoo ntawm arrhythmia. Rau cov neeg mob uas muaj kab mob plawv, qhov kev pheej hmoo no yuav siab dua.
Qhov hnyav: Cov tshuaj tiv thaiv kab mob plawv tsis zoo yuav ua rau muaj sia nyob - hem thiab yuav tsum tau saib xyuas thiab kho raws sijhawm.
Kev puas tsuaj rau lub siab thiab lub raum ua haujlwm
Cov tsos mob: Lub siab ua haujlwm tsis zoo (xws li nce transaminase, jaundice, thiab lwm yam), lub raum tsis ua haujlwm (xws li siab creatinine, proteinuria, thiab lwm yam).
Mechanism ntawm qhov tshwm sim: Cov tshuaj lom metabolites tuaj yeem tsim tawm thaum lub sijhawm metabolism hauv lub cev, uas yuav tsum tau tawm ntawm lub siab thiab ob lub raum. Lub sij hawm ntev lossis siab - kev siv tshuaj azithromycin tuaj yeem ua rau lub siab thiab lub raum ua haujlwm puas.
Kev tshwm sim: Lub siab thiab lub raum ua haujlwm tsis zoo yog qhov tsis tshua muaj ntawm cov neeg siv azithromycin, tab sis thaum nws tshwm sim, nws yuav muaj kev cuam tshuam loj rau cov neeg mob.
Kev tsis zoo tshwm sim hauv cov ntshav
Cov tsos mob: leukopenia, thrombocytopenia, neutropenia, thiab lwm yam.
Mechanism ntawm qhov tshwm sim: Azithromycin tuaj yeem cuam tshuam cov pob txha pob txha hematopoietic kev ua haujlwm, ua rau muaj qhov txawv txav hauv cov ntshav.
Kev tshwm sim: Cov kev tsis zoo tshwm sim hauv cov ntshav yog qhov tsawg ntawm cov neeg siv azithromycin, tab sis thaum lawv tshwm sim, kev saib xyuas ze thiab kho raws sijhawm yog qhov tsim nyog.
Dysbacteriosis
Cov tsos mob: Kev siv sijhawm ntev tuaj yeem ua rau dysbiosis ntawm plab microbiota, uas tuaj yeem ua rau muaj kab mob fungal xws li candidiasis.
Mechanism ntawm qhov tshwm sim: Nws inhibits kev loj hlob ntawm lub plab microbiota ib txwm, cuam tshuam qhov sib npaug ntawm plab microbiota, thiab muab txoj hauv kev loj hlob rau cov kab mob xws li fungi.
Kev tshwm sim: Microbial dysbiosis muaj ntau dua rau cov neeg mob uas tau siv azithromycin ntev.
Lwm yam kev tsis zoo tshwm sim
Cov tsos mob: qaug zog, txawv txav, qaug zog, tsis xis nyob, mob ntawm qhov chaw txhaj tshuaj, mob hauv zos, thiab lwm yam.
Mechanism ntawm qhov tshwm sim: Cov kev cuam tshuam tsis zoo no yuav cuam tshuam nrog cov tshuaj pharmacological, qhov sib txawv ntawm tus kheej, lossis kev tswj hwm ntawm azithromycin.
Kev tshwm sim: Cov kev phiv tshuaj no kuj tsis tshua muaj ntawm cov neeg siv azithromycin, tab sis kuj yuav ua rau tsis xis nyob rau cov neeg mob.
Kev ntsuas los daws cov teebmeem tsis zoo
Cov tsos mob me me
Gastrointestinal reactions: Rau cov tsos mob me xws li xeev siab, ntuav, mob plab, raws plab, thiab lwm yam, sim noj nws tom qab noj mov kom txo tau qhov mob ntawm plab hnyuv. Yog tias tsim nyog, cov tshuaj xws li omeprazole tuaj yeem noj raws li tus kws kho mob qhia kom txo cov tsos mob. Rau cov tsos mob me me xws li pob khaus thiab khaus khaus, kev siv cov tshuaj calamine hauv zos lossis kev siv tshuaj tiv thaiv qhov ncauj xws li loratadine tuaj yeem sim. Lub caij no, nws yog ib qho tseem ceeb uas yuav tsum tau saib xyuas cov kev hloov pauv ntawm cov tsos mob thiab nrhiav kev kho mob sai sai yog tias cov tsos mob hnyav zuj zus ntxiv. Rau cov kev phiv tshwm sim xws li qaug zog, txawv txav, thiab qaug zog, nws raug nquahu kom sim so, kho kev noj haus, thiab lwm txoj hauv kev los txo cov tsos mob. Yog tias cov tsos mob tshwm sim los yog hnyav zuj zus, nrhiav kev kho mob sai.
Kev phiv loj heev
Yog tias muaj kev fab tshuaj hnyav xws li ua pa nyuaj thiab anaphylactic shock tshwm sim, tshuaj yuav tsum tau nres tam sim ntawd thiab yuav tsum tau nrhiav kev kho mob. Cov kws kho mob yuav muab tshuaj xws li adrenaline thiab glucocorticoids rau kev kho mob xwm txheej ceev. Yog tias cov tsos mob xws li palpitations, mob hauv siab, thiab ntshav siab tsis tshua muaj tshwm sim, nrhiav kev kho mob tam sim ntawd thiab tau txais kev kuaj xyuas xws li electrocardiograms. Thaum tsim nyog, cov kws kho mob yuav muab tshuaj tua kab mob los yog ua lwm yam kev kho mob xwm txheej ceev. Yog tias cov tsos mob xws li lub siab ua haujlwm tsis zoo thiab lub raum tsis ua haujlwm tshwm sim, cov tshuaj yuav tsum raug tso tseg tam sim ntawd thiab yuav tsum nrhiav kev kho mob. Cov kws kho mob tuaj yeem kho cov phiaj xwm kho mob lossis muab cov phiaj xwm kev kho mob xws li kev tiv thaiv lub siab thiab kev khaws cia rau lub raum raws li cov txiaj ntsig kev kuaj mob.
Kev tiv thaiv kev tiv thaiv tsis zoo
Ua raws li tus kws kho mob cov lus qhia nruj me ntsis thaum noj tshuaj
Cov neeg mob yuav tsum ua raws li tus kws kho mob cov lus qhia nruj me ntsis txog kev noj tshuaj, lub sij hawm siv tshuaj, txoj kev tswj hwm, thiab lwm yam. Tsis txhob nce lossis txo qhov ntau npaum lossis hloov cov tshuaj ntawm koj tus kheej.
Nkag siab txog cov tshuaj contraindications thiab ceev faj
Ua ntej siv, cov neeg mob yuav tsum paub txog contraindications thiab ceev faj ntawm cov tshuaj. Piv txwv li, nws yog contraindicated rau cov tib neeg tsis haum rau azithromycin; Siv ceev faj rau cov neeg mob uas muaj lub siab ua haujlwm tsis zoo; Tsis txhob koom nrog kev tswj hwm nrog qee yam tshuaj xws li antacids, ergots, thiab lwm yam.
Ua tib zoo saib xyuas qhov tsis zoo tshwm sim
Thaum siv, cov neeg mob yuav tsum saib xyuas cov kev hloov pauv hauv lawv tus kheej cov tsos mob. Yog tias muaj cov tsos mob tsis xis nyob, nrhiav kev kho mob sai thiab qhia rau tus kws kho mob tiastshuaj azithromycinyog siv.
Tsis txhob siv sijhawm ntev - siv ntau
Kev siv lub sijhawm ntev tuaj yeem ua rau muaj kev pheej hmoo ntawm kev tsis zoo. Yog li ntawd, tshwj tsis yog tus kws kho mob qhia tshwj xeeb, yuav tsum zam kev siv sijhawm ntev -.
FAQ
Vim li cas azithromycin muab rau 3 hnub nkaus xwb?
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Feem ntau, cov koob tshuaj azithromycin ib txwm yog 500 mg ib hnub ib zaug rau 3 mus rau 10 hnub; cov kev tshawb fawb tau qhia tiasazithromycin yog cov tshuaj tua kab mob zoo tshaj plaws los kho cov kab mob me thiab nruab nrabTsis pub dhau 3 hnub thaum piv rau cov tshuaj tua kab mob ntxiv, xws li amoxiclav (amoxicillin thiab potassium clavulanate).
Kuv yuav tsum tsis txhob noj dab tsi thaum noj azithromycin?
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Ceev faj nrog lwm cov tshuajantacids rau plab zom mov. ergotamine los yog dihydroergotamine - rau migraine. warfarin, los pab tiv thaiv cov ntshav txhaws. ciclosporin lossis tacrolimus - cov tshuaj tiv thaiv koj lub cev tiv thaiv kab mob ntau dhau.
Nws siv sijhawm ntev npaum li cas azithromycin ua haujlwm?
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Macrolide tshuaj tua kab mob yog ob qho kev xaiv. Azithromycin pib ua haujlwm txog2 mus rau 3 teev tom qab koj thawj koob tshuaj. Erythromycin siv sijhawm li 1 teev los pib ua haujlwm. Nws feem ntau yuav siv li ob peb hnub ua ntej koj pib hnov zoo tom qab pib tshuaj tua kab mob macrolide.
Qhov twg daim ntawv tso cai ua lneed?
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304 stainless hlau ua tau raws li cov kev cai thoob ntiaj teb ntawm qib zaub mov, 316 stainless hlau tsis yog qib zaub mov lossis qib kho mob nkaus xwb. Txawm li cas los xij, kev siv qib kev kho mob no ua lub khob ntim khoom yuav tsis coj cov txiaj ntsig ntxiv rau txhua tus. Vim li cas thiaj hu 304 lossis 316? Qhov no feem ntau txhais raws li cov khoom muaj pes tsawg leeg . 316 stainless hlau tsis zoo li cov khoom siv ntxhia, tom qab siv tau tuaj yeem tso qee yam tshuaj los txhawb tib neeg kev nqus.
Cim npe nrov: Azithromycin CAS 83905-01-5, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom