Eriodictyol glycosidesyog ib qho flavonoid cais los ntawm txiv qaub. Nws yog flavone-7-O-glycoside ntawm flavonoid ursodiol thiab disaccharide rutose. Nws yog ib qho muaj zog antioxidant. Lub teeb daj hmoov, soluble hauv methanol, ethanol, DMSO, thiab lwm yam organic solvents, muab tau los ntawm txiv qaub thiab citrus txiv hmab txiv ntoo ntoo. Eriocitrin inhibits kev loj hlob ntawm hepatoma hlwb los ntawm upregulating p53, cyclin A, cyclin D3, thiab Cdk6. Eriocitrin ua rau apoptosis los ntawm kev ua kom muaj kev cuam tshuam hauv nruab nrog cev hauv mitochondria. Nws muaj ntau nyob rau hauv lemons. Nws yog feem ntau hu ua txiv qaub flavone los yog citrus flavone. Nws yog ib qho ntawm cov nroj tsuag pigments uas coj xim rau txiv hmab txiv ntoo thiab paj. Cov tshuaj tua kab mob no kuj tseem ceeb hauv peppermint infusion (38% hauv ib txoj kev tshawb fawb). Cov tshuaj muaj lipid-txo cov nyhuv hauv hepatocytes. Raws li kev noj zaub mov ntxiv, nws feem ntau yog siv ua ke nrog B, C vitamins, thiab lwm yam khoom siv hauv khw, tab sis tsis muaj kev siv tshuaj kho mob lossis FDA pom zoo daim ntawv thov ntawm cov khoom xyaw.
ERIOCITRIN Extracted chemicals Remark: Firstly, in China market, it haa not been widely used in China market, we are the largest manufacturer, and the general qty of per order is gram grade. We have two specifications on sale: (1)HPLC>95.0%, 100-120g in stock 100g, Unit price: $100/g, Total price: $10,000 1kg, if you confirm to purchase 1kg, we arrange our R&D Dept. calculate the cost for you. (2)HPLC>98.0%. HS Code: 2915709000 Cov khoom lag luam phom sij: Tsis muaj cov khoom lag luam Siv tau lub sijhawm hais lus: 7 hnub.
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C.F |
C27H32O15 |
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E.M |
596 |
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M.W |
597 |
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m/z |
596 (100.0%), 597 (29.2%), 598 (3.1%), 598 (2.7%), 598 (1.4% |
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E.A |
C, 54.36; H, 5.41; O, 40.23 |
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Melting point 161-190 ° C, boiling point 956.9 ± 65.0℃(Predicted), ceev 1.77, Cia tej yam kev mob Inert cua, 2-8 ° C, Acidity coefficient (pKa) 7.15 ± 0.40 (Predicted 3), 4 BRN cov lus qhia zoo 22-24 / 25 , WGK Germany 3 , F 10-21
Eriodictyol glycosidestuaj yeem tiv thaiv oxidative kev nyuaj siab raug mob los ntawm kev tawm dag zog hnyav hauv daim siab nas, thiab txo cov ntshav lipid. Lub peev xwm antioxidant ntawm saintoside muaj zog dua li ntawm hesperidin thiab naringin. Saintoside tuaj yeem tiv thaiv oxidative kev nyuaj siab raug mob los ntawm kev tawm dag zog hnyav hauv nas daim siab thiab txo cov ntshav lipid. Saintoside muaj zog antioxidant muaj peev xwm tshaj hesperidin thiab naringin. Txoj kev npaj ntawm saintoside suav nrog cov hauv qab no: cov tshuaj tiv thaiv demethylation, kev npaj cov khoom nyoos, thiab kev ua kom zoo. Hesperidin tau txais los ntawm hesperidin los ntawm demethylation. Txoj kev npaj ntawm Saint nyom glycosides yog ib qho - cov tshuaj tiv thaiv kab mob los npaj cov nyom nyom glycosides. Hesperidin yog demethylated los ntawm demethylation reagent kom tau txais cov nyom nyom glycosides. Cov khoom siv raw ntawm hesperidin yog pheej yig, cov kauj ruam demethylation cov tshuaj tiv thaiv tsawg dua, kev kho mob yooj yim, thiab cov txiaj ntsig thiab cov khoom zoo yog tsim rau loj - nplai ntau lawm.
Kev ua haujlwm tseem ceeb antioxidant tuaj yeem pab tshem tawm cov dawb radicals thiab txo qhov kev puas tsuaj ntawm oxidative kev nyuaj siab rau tib neeg lub hlwb. Eriocitrin yog ib qho kev sib txuas tsim los ntawm ester bonding ntawm Eriodictyol thiab qab zib molecules. Raws li cov nroj tsuag theem nrab metabolite nrog cov txiaj ntsig tshuaj muaj txiaj ntsig, Eriocitrin muaj kev siv dav hauv thaj chaw xws li tshuaj, khoom noj qab haus huv, thiab tshuaj pleev ib ce.
1. Anti-inflammatory kev ua:
Eriocitrin muaj cov tshuaj tiv thaiv zoo - inflammatory zog thiab muaj peev xwm inhibit inflammatory cov tshuaj tiv thaiv thiab tso tawm inflammatory mediators. Qhov no ua rau nws muaj cov khoom xyaw zoo tshaj plaws rau kev tsim tshuaj tiv thaiv - cov tshuaj tiv thaiv kab mob thiab cov khoom tu tawv nqaij.
2. Kev tiv thaiv kev ua xua:
Eriocitrin muaj cov tshuaj tiv thaiv kev ua xua thiab tuaj yeem txo cov kev tsis haum tshuaj thiab cov tsos mob. Nws yog dav siv nyob rau hauv kev tsim cov tshuaj tiv thaiv tsis haum tshuaj thiab allergen blockers.
Shengcao glycoside muaj cov tshuaj muaj zog pharmacological, feem ntau cuam tshuam hauv cov hauv qab no:
Antioxidant nyhuv
Shengcao glycoside yog ib qho antioxidant zoo uas tuaj yeem tshem tawm cov dawb radicals hauv lub cev thiab tiv thaiv cov hlwb los ntawm kev puas tsuaj oxidative. Nws lub peev xwm antioxidant muaj zog dua li lwm cov flavonoids xws li hesperidin thiab naringin. Yog li ntawd, sage glycoside yog dav siv los ua ib qho antioxidant hauv kev lag luam zaub mov thiab dej haus kom ntev lub neej txee thiab ruaj khov ntawm cov khoom.
Inhibit oxidative kev nyuaj siab puas
Kev tshawb fawb tau pom tias Shengcao glycoside tuaj yeem cuam tshuam oxidative kev nyuaj siab puas tsuaj los ntawm kev tawm dag zog hnyav hauv daim siab nas. Oxidative stress yog lub xeev pathological uas lub cev tsim tawm ntau dhau ntawm cov khoom siv molecules xws li cov pa oxygen reactive thiab reactive nitrogen hom thaum raug rau ntau yam teeb meem stimuli, ua rau muaj kev tsis txaus ntawm oxidative thiab antioxidant systems thiab ua rau cov ntaub so ntswg puas. Shengcao glycoside tuaj yeem txo oxidative kev nyuaj siab puas tsuaj thiab tiv thaiv kev ua haujlwm ntawm lub cev xws li daim siab los ntawm nws cov nyhuv antioxidant.
Cov nyhuv hypolipidemic
Shengcao glycoside kuj muaj cov nyhuv ntawm cov ntshav lipids. Hyperlipidemia yog hais txog kev nce qib ntawm cov roj cholesterol hauv plasma lossis triglycerides, uas yog qhov tseem ceeb ntawm kev pheej hmoo rau cov kab mob plawv xws li atherosclerosis thiab kab mob plawv. Shengcao glycoside tuaj yeem tiv thaiv qhov tshwm sim ntawm cov kab mob plawv los ntawm kev tswj cov lipid metabolism, txo cov roj cholesterol thiab triglyceride hauv plasma.
Eriodictyol glycoside muaj ntau yam kev siv hauv ntau lub teb vim nws cov tshuaj pharmacological tshwj xeeb.
Kev lag luam zaub mov thiab dej haus
Shengcao glycoside, raws li lub ntuj antioxidant, yog siv dav hauv kev lag luam zaub mov thiab dej haus. Nws tuaj yeem muab ntxiv rau ntau yam khoom noj, xws li roj, khoom noj nqaij, khoom noj siv mis, khoom ci, thiab lwm yam, kom ntev lub txee lub neej thiab ruaj khov ntawm cov khoom. Tib lub sijhawm, Shengcao glycoside tuaj yeem txhim kho xim thiab saj ntawm cov khoom noj, thiab txhim kho cov khoom zoo. Hauv kev lag luam dej haus, sage glycoside tuaj yeem siv los ua ib qho ntxiv hauv cov dej haus ua haujlwm, muab cov txiaj ntsig kev noj qab haus huv xws li antioxidant thiab lipid- txo cov teebmeem.
Kev kho mob teb
Shengcao glycoside kuj muaj peev xwm siv tau tus nqi hauv kev kho mob. Vim nws cov antioxidant thiab lipid - txo cov teebmeem, Shengcao glycoside tuaj yeem siv los kho cov kab mob ntsig txog oxidative stress thiab dyslipidemia. Piv txwv li, nws tuaj yeem siv los ua cov tshuaj pab kho mob rau kev tiv thaiv thiab kho cov kab mob plawv, ntshav qab zib, rog thiab lwm yam kab mob. Tsis tas li ntawd, Shengcao glycoside kuj tuaj yeem siv los ua cov khoom siv rau kev noj qab haus huv los tsim cov khoom noj qab haus huv nrog antioxidant thiab lipid- txo qis zog.
Kev lag luam tshuaj pleev ib ce
Shengcao glycoside kuj muaj ntau yam kev siv hauv kev lag luam tshuaj pleev ib ce. Vim nws cov nyhuv antioxidant, Shengcaoside tuaj yeem ntxiv rau ntau yam tshuaj pleev ib ce, xws li lub ntsej muag cream, qhov muag cream, lipstick, thiab lwm yam, los muab kev tiv thaiv - laus, ntxuav hniav dawb thiab lwm yam teebmeem. Tib lub sijhawm, Shengcao glycoside tuaj yeem txhim kho kev ruaj ntseg thiab kev nyab xeeb ntawm cov tshuaj pleev ib ce, thiab txhim kho cov khoom zoo.
Hauv kev ua liaj ua teb
Shengcao glycoside kuj muaj peev xwm siv tau tus nqi hauv kev ua liaj ua teb. Kev tshawb fawb tau pom tias Shengcao glycoside muaj qee yam cuam tshuam rau cov kab mob ntawm cov nroj tsuag, thiab yog li ntawd tuaj yeem siv los ua tus neeg saib xyuas kev noj qab haus huv rau cov kab mob nroj tsuag. Tsis tas li ntawd, Shengcao glycoside kuj tseem tuaj yeem ua tus tswj kev loj hlob ntawm cov nroj tsuag, txhawb kev loj hlob thiab kev loj hlob ntawm cov nroj tsuag, thiab txhim kho qoob loo thiab zoo.
Cov Khoom Siv Tshwj Xeeb Thiab Daim Ntawv Thov
Cov dej haus ua haujlwm
Shengcao glycoside tuaj yeem siv los ua ib qho ntxiv hauv cov dej haus, muab cov txiaj ntsig kev noj qab haus huv xws li antioxidant thiab lipid - txo cov teebmeem. Piv txwv li, qee cov dej haus ua kis las thiab cov dej haus muaj zog muaj cov sage glycosides los pab cov neeg ncaws pob txo kev qaug zog thiab txhim kho kev ua kis las. Nyob rau tib lub sijhawm, cov dej haus no tuaj yeem muab cov khoom noj nplua nuj xws li cov vitamins thiab minerals, ua kom tau raws li qhov xav tau ntawm lub zog ntawm cov neeg ncaws pob thaum lub sijhawm ua haujlwm.
Khoom noj khoom haus
Shengcao glycoside tuaj yeem siv los ua raw khoom rau cov khoom noj qab haus huv, thiab siv los tsim cov khoom noj qab haus huv nrog antioxidant thiab lipid- txo qis zog. Piv txwv li, qee cov tshuaj tiv thaiv - oxidation capsules, lipid txo cov tshuaj ntsiav thiab lwm yam khoom tau ntxiv Shengcaoside los pab tib neeg tiv thaiv kab mob plawv, ntshav qab zib thiab lwm yam kab mob. Cov khoom noj qab haus huv no feem ntau muaj qhov zoo ntawm kev nqa tau yooj yim thiab nqa tau yooj yim, haum rau cov neeg ntawm txhua lub hnub nyoog.
Tshuaj pleev ib ce
Shengcaoside tuaj yeem muab ntxiv rau ntau yam tshuaj pleev ib ce, xws li lub ntsej muag cream, qhov muag cream, lipstick, thiab lwm yam, los muab kev tiv thaiv -aging, whitening thiab lwm yam teebmeem. Piv txwv li, qee qhov siab - kawg lub ntsej muag qab zib thiab lub qhov muag cream tau ntxiv secoside los pab tib neeg txhim kho daim tawv nqaij so, wrinkles thiab lwm yam teeb meem, kom cov tawv nqaij ntau dua thiab du. Nyob rau tib lub sijhawm, cov tshuaj pleev ib ce no tseem tuaj yeem muab cov dej noo thiab cov txiaj ntsig zoo, ua tau raws li cov neeg xav tau kev saib xyuas ntawm daim tawv nqaij.
Cov tshuaj tiv thaiv kab mob cog
Shengcao glycoside tuaj yeem siv los ua tus neeg saib xyuas kev noj qab haus huv rau cov kab mob nroj tsuag, tiv thaiv thiab tswj ntau yam kab mob nroj tsuag. Piv txwv li, qee cov txiv hmab txiv ntoo thiab zaub siv sage glycosides hauv kev tiv thaiv kab mob thiab kev tswj hwm kom tsis txhob muaj kev loj hlob thiab kev loj hlob ntawm cov kab mob, txo qhov tshwm sim thiab kis kab mob. Tus neeg saib xyuas kev noj qab haus huv no muaj qhov zoo xws li kev tiv thaiv ib puag ncig thiab kev nyab xeeb, thiab tsis muaj kev phom sij rau ib puag ncig thiab tib neeg kev noj qab haus huv.
Kev Tshawb Fawb Thiab Kev Loj Hlob
Nrog rau kev txhim kho tas mus li ntawm tib neeg txoj kev nrhiav kev noj qab haus huv thiab lub neej zoo, daim ntawv thov kev cia siab ntawm Shengcao glycoside, raws li lub ntuj thiab noj qab nyob zoo, tau dhau los ua qhov dav. Nyob rau hauv lub neej yav tom ntej, kev tshawb fawb thiab kev loj hlob ntawm Shengcao glycoside yuav nthuav tawm cov hauv qab no:
Tam sim no, pharmacological mechanism ntawm Shengcao Ci glycoside tsis tob txaus. Nyob rau hauv lub neej yav tom ntej, nws yog ib qho tsim nyog yuav tsum ntxiv dag zog rau kev tshawb fawb ntawm nws cov tshuaj antioxidant thiab lipid- txo cov teebmeem, muab lub hauv paus rau kev txhim kho cov tshuaj tshiab thiab cov khoom noj qab haus huv.
Ntxiv nrog rau kev lag luam zaub mov thiab dej haus, kev lag luam tshuaj, kev lag luam tshuaj pleev ib ce, thiab kev lag luam ua liaj ua teb, yav tom ntej kuj tseem tuaj yeem tshawb nrhiav daim ntawv thov ntawm Shengcao Ci glycoside hauv lwm qhov chaw xws li kev lag luam pub noj thiab kev tiv thaiv ib puag ncig kom nthuav dav nws daim ntawv thov.
Tam sim no, tseem muaj qee qhov teeb meem nrog kev rho tawm thiab purification thev naus laus zis ntawm Shengcao glycoside, xws li cov extraction efficiency thiab nyuaj purification. Nyob rau hauv lub neej yav tom ntej, nws yog ib qho tsim nyog los txhim kho kev rho tawm thiab purification thev naus laus zis ntxiv txhawm rau txhim kho cov txiaj ntsig thiab purity ntawm Shengcao glycoside thiab ua tau raws li kev lag luam xav tau.
Raws li ib qho kev sib xyaw nrog cov ntawv thov dav dav, kev tshawb fawb thiab kev txhim kho ntawm Shengcao glycoside xav tau kev koom tes thoob ntiaj teb thiab kev sib pauv. Nyob rau hauv lub neej yav tom ntej, peb tuaj yeem ntxiv dag zog rau kev koom tes thiab kev sib pauv nrog cov phooj ywg thoob ntiaj teb los koom tes txhawb kev tshawb fawb thiab kev loj hlob ntawm Shengcao glycoside.
Peb yog cov chaw tsim khoomEriodictyol Glycoside.
Siv hesperidin (Eriodictyol) ua cov khoom siv raw, cov kauj ruam ntawm kev tsim cov tshuaj ntuj tsim tshuaj eriocitrin (Euxanthone) los ntawm txhuas trichloride-pyridine demethylation cov tshuaj tiv thaiv yog raws li nram no:
Hesperidin + 3AlCl3 + 3C5H5N → eriocitrin + 3HCl + 3C5H6N
Dissolve hesperidin nyob rau hauv qhuav organic hnyav, xws li dichloromethane los yog diethyl ether, los npaj cov tshuaj tiv thaiv substrate tov. Xyuas kom tseeb tias cov hesperidin yog tag nrho yaj hauv cov tshuaj.
Maj mam ntxiv aluminium trichloride (AlCl3) dropwise rau cov tshuaj hesperidin thaum ua kom qhov kub ntawm cov tshuaj tiv thaiv qis dua 0 degree. Aluminium trichloride yog cov catalyst rau cov tshuaj tiv thaiv no thiab tuaj yeem ua rau cov tshuaj tiv thaiv demethylation.
Tom qab lub dropwise ntxiv ntawm txhuas trichloride, txuas ntxiv maj mam ntxiv pyridine dropwise rau hauv cov tshuaj tiv thaiv substrate tov. Pyridine yog ib qho alkaline reagent uas neutralizes HCl tsim nyob rau hauv cov tshuaj tiv thaiv thiab muab alkaline tej yam kev mob.
Txuas ntxiv mus do cov tshuaj tiv thaiv sib tov thiab ua kom kub hauv qab 0 degree. Cov tshuaj tiv thaiv feem ntau yuav tsum tau nqa tawm nyob rau hauv qhov kub tsis tshua muaj kev kub ntxhov los tswj cov kev cuam tshuam sab ntawm cov tshuaj tiv thaiv thiab txhim kho cov purity ntawm cov khoom.
Tom qab cov tshuaj tiv thaiv tiav lawm, cov dej khov nab kuab tau maj mam ntxiv dropwise rau cov tshuaj tiv thaiv sib tov rau hydrolyze unreacted aluminium chloride thiab methylated khoom. Txuas ntxiv mus do cov tshuaj tiv thaiv sib tov kom ua tiav hydrolysis.
Cov txheej txheem organic thiab txheej txheej aqueous hauv cov tshuaj tiv thaiv sib xyaw tau sib cais los ntawm txoj kev rho tawm. Cov txheej txheem organic muaj cov khoom lag luam eriocitrin (Euxanthone), thaum cov txheej txheem dej muaj cov ntsev inorganic thiab lwm yam dej -soluble impurities.
Hloov cov organic txheej mus rau lub evaporator teb, tshem tawm cov organic hnyav thiab cia kom qhuav. Cov khoom tau tuaj yeem raug ua kom huv si ntxiv xws li kem chromatography, crystallization, thiab lwm yam.
Cov lus nug nquag
eriodictyol glycoside yog dab tsi?
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Eriocitrin (eriodictyol glycoside) yoga flavanone-7-O-glycoside ntawm flavanone eriodictyol thiab disaccharide rutinose. Nws feem ntau pom muaj nyob rau hauv txiv qaub thiab lwm yam txiv hmab txiv ntoo citrus. Nws yog colloquially hu ua txiv qaub flavonoid los yog citrus flavonoid, ib qho ntawm cov nroj tsuag pigments uas coj xim rau txiv hmab txiv ntoo thiab paj.
Cov zaub mov twg muaj eriodictyol hauv nws?
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Eriodictyol yog ib txwm tshwm sim flavonoid feem ntau pom hauvcitrus txiv hmab txiv ntoo, xws li txiv qaub, txiv kab ntxwv, thiab cov nroj tsuag zoo li yerba santa. Nws tau txais kev txaus siab rau kev tshawb fawb tseem ceeb vim nws lub zog antioxidant, tiv thaiv - mob, thiab cov teebmeem neuroprotective.
Cov kua txiv qaub puas muaj eriocitrin?
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Eriocitrin zoo faib nyob rau hauv tsev neeg citrus, tshwj xeeb tshaj yog nyob rau hauv txiv qaub peels thiab kua txiv hmab txiv ntoo.
eriodictyol 7 O glucoside yog dab tsi?
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Eriodictyol 7-O-beta-D-glucopyranoside yogib qho flavanone glycoside uas yog eriodictyol txuas nrog beta-D-glucopyranosyl residue ntawm txoj hauj lwm 7 ntawm kev sib txuas glycosidic. Nws yog Nrf2 activator thiab muab kev tiv thaiv tiv thaiv cisplatin-induced toxicity.
Cim npe nrov: eriodictyol glycoside cas 13463-28-0, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom