Idra 21 Hmoov(Idra -21 hmoov) yog hmoov dawb dawb nrog lub npe tshuaj lom neeg 7-}}}}}}}}}}}}}} dioxide {}} nws zoo nkaus li ib tug dawb kom tawm dawb crystalline hmoov, uas tsis muaj qhov sib txawv ntawm 259 mm) hauv dmo thiab me ntsis soluble hauv dej (0}} 93 g / l, 25℃) {{{{{. Nws tuaj yeem khaws cia rau 3 xyoos nyob rau hauv hmoov xeev ntawm-20 degree; Khw ntawm 4℃rau 2 xyoos; Khaws rau hauv lub xeev hnyav ntawm -80℃rau 6 lub hlis; -Tsy-}.}}}} Tus txiv neej zoo siab, thiab yog li ua tau zoo tshaj plaws Synaptic kis tau zoo nkauj ( Idra -21 Tseem dav txhim kho cov haujlwm uas muaj hnub nyoog li ntawm 34% ntxiv rau cov pab pawg sib luag (thiab tom qab ua haujlwm sib txuam Cov laus liab liab yog qhov tsis muaj zog, tab sis ib tus neeg rhiab siab dua. Nws yuav txo cov neuronal kev puas tsuaj los ntawm kev tswj hwm cov glutamatergic system, tab sis cov txheej txheem tshwj xeeb tseem xav tau kev tshawb fawb ntxiv.
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| Khoom npe | Idra 21 Hmoov | IDRA 21 Capsules |
| Khoom Yam | Hmoov | Tsoom qab |
| Khoom Siv Purity | Ntau dua los yog sib npaug rau 99% | Ntau dua los yog sib npaug rau 99% |
| Cov Khoom Qhia Khoom Khoom | 100g / 1kg / etc . | 5mg / 25mg / 50mg |
| Khoom daim ntawv | Organic Synthesis | Noj ib leeg |
IDRA 21 Hmoov Coa
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Idra 21 Hmoov, raws li ib tug xaiv siab ampe kev txhim kho tus nqi, tab sis kev ua kom zoo dua ntawm kev siv tshuaj tiv thaiv kev nyab xeeb, thiab kev tshuaj xyuas kev nyab xeeb ntev, thiab kev qhia meej txog kev ua haujlwm ntev xav tau los txhawb nws txhais lus los ntawm kev tshawb fawb los ntawm kev tshawb fawb txog kev kho mob.
Cov tub ntxhais tseem ceeb ntawm idra -21 cov hmoov yog ua tus muaj txiaj ntsig zoo, uas tau txais txiaj ntsig zoo, muaj txiaj ntsig zoo hauv kev tshawb nrhiav kev tsis taus Kev kho mob, thiab Neuroprot. ampa recaptatory synaptic muab kwv yees li 70% kev sib haum xeeb, ua rau kev kaw hluav taws xob, ua rau kev kaw mus kuaj thiab teeb liab Kev cuam tshuam . idra-21}}}}}} Piv txwv, hauv Vitro Hippocampal Neuron sim, Idra -21 ({}}}} {{} Tau muaj zog dua ntawm Am1} muaj zog ne} muaj zog dua cov ntshav siab, thiab qis neurotoxicity {14. kev sim tsiaj tau pom tias muaj koob tshuaj lom neeg yuav luag tsis muaj kev tuag
Kev Txawj Ntse Kev Txhim Kho: Los ntawm cov kev sim tsiaj rau cov kev tshawb fawb ua ntej
Kev Tshawb Fawb Txog Idra -21 Nyob rau hauv lub tshav pob ntawm kev txawj ntse yog ib qho ntawm cov txiaj ntsig muaj txiaj ntsig, tshwj xeeb} {}} ({6}} MG / kg, ib zaug txhua peb hnub, rau 3 lub lis piam dhau los ua haujlwm, feem ntau yog qhov ua haujlwm ntev (thiab tom qab kev nkag siab ntev) Liab: Txawm hais tias idra-21 (nyob rau hauv tib cov neeg muaj zog, thiab cov neeg laus yog rhiab rau cov tshuaj me, uas ua rau lub luag haujlwm luv luv latency.
Qhov no qhia tau tias idra -21 muaj peev xwm hloov kho kev txawj ntse {4}6-24 {4} tawm tswv yim nws cov peev xwm neuroprotrotive txoj kev raug mob {}} Txawm li cas los xij Ntev ntev ntawm kev ua . Txoj Haujlwm Kev Txhim Kho ntawm Rhesthe Anesent, txo qhov kev pab cuam thiab kev txhim kho kev ua kom tsis nco qab.
Cov Cuab Yeej Tshawb Fawb Neuroscience: Mechanism tshawb nrhiav thiab hom phiaj tsim nyog
Idra 21 Hmoov, raws li ib tug xaiv siab ampa receptor PAM, yog dav siv nyob rau hauv cov pa hluav taws xob hauv synaptiation (LTD) {{{i6 4 4}} tuaj yeem txhim kho LTP InductIicy los ntawm lub sijhawm ua haujlwm ampa kom muaj zog, hauv Hippocampal dos siab, qhia lub luag haujlwm ntawm AMPA receptor desensitization hauv synapic plyi kev tswj hwm . Cov kab ke ntawm idra, tab sis txhim kho cov txiaj ntsig ntawm cov kev ua kom pom tseeb ntawm txoj kev teeb tsa ntawm GlutamaterGic system, uas tuaj yeem paub qhov sib txawv ntawm Kev txhim kho lub cev sib txawv ntawm kev txhim kho ncaj qha thiab kev ua kom pom tseeb ntawm cov tsiaj txhu (rhas} Xyaum .
Raws li nws cov kev ua kom haum thiab kev ua kom muaj txiaj ntsig zoo hauv cov kab mob AMPACH) Ampa receptor muaj nuj nqi {. Cov ntaub ntawv pov thawj tom qab nkag mus rau qhov kev nco txog kev ua haujlwm, tab sis kev sib tw ntawm kev ua haujlwm lub hlwb, tab sis kev nkag siab nrog cov kab mob tsis txaus, uas cuam tshuam nrog cov kab mob tsis txaus prefontex {{{}} idra-21 Cov qoj ib ce ampra Kev ntsuas . Cov xwm txheej ne3}} Tus qauv siv hluav taws xob tau cuam tshuam nrog kev cuam tshuam nrog kev cuam tshuam nrog kev cuam tshuam ntawm amazeopia, tab sis nws yog ib qho tsim nyog kom sib npaug nrog cov peev xwm neurotoxicity Kev phom sij .
Kev Nyab Xeeb Kev Nyab Xeeb thiab Dose Kev Tswj Xyuas: Kev ceev ceev thaum lub sijhawm tshawb xyuas
Txawm hais tias idra -21 Tau qhia kev nyab xeeb tsiaj, nws daim ntawv thov tseem yuav ua rau tswj hwm cov tshuaj thiab kev sim:
Koob tshuaj-nyob twj ywm neurotoxicity
Nyob rau hauv cov kev sim vito pom tias idra -21 ({} {} {} {}}}}}}}} {} mg / kg) kom tsis txhob neurotoxicity .
Kev ua kom zoo ntawm solubility thiab ruaj khov
Idra -21 yog soluble me ntsis hauv DMSo (25 mg / ml, 107. 44 mm). Txhawm rau txhim kho Bioavailability, nws yog qhov tsim nyog los ua kom zoo rau kev kho cov tshuaj peg300, kaum ntsawj - - Cd) thiab se}}
Kev Noj Tshuaj Rau Lwm Tus
Older animals are more sensitive to Idra-21 and require dosage adjustments based on age, weight, and genotype. For example, elderly rhesus monkeys have weaker reactions at the same dose, but individual differences are greater, and treatment plans need to be optimized through pharmacological monitoring.
Yav Tom Ntej Prospaps: Txoj Kev Hloov Pauv Los Ntawm Kev Tshawb Fawb rau Chaw Kho Mob
Kev sivIdra 21 HmoovTau nthuav tawm los ntawm kev tshawb fawb yooj yim rau cov neeg yuav kho tau cov teb, tab sis nws cov kev tshawb fawb soj ntsuam tseem yuav tsum tau kov yeej cov khaub ncaws hauv qab no:
Kev Ntsuam Xyuas Kev Nyab Xeeb Kev Nyab Xeeb
Nyob rau tam sim no, kev tshawb fawb feem ntau yog qhia rau lub sijhawm luv luv (tsawg dua lossis sib npaug ntawm 3 lub lis piam) kev nyab xeeb, thiab lub zog tiv thaiv kev nyab xeeb, thiab cov khoom siv tsis tau zoo {}}
Kws Tshuaj Kho Mob
Txawm hais tias idra -21 muaj qhov ncauj ntawm kev tso tawm los yog xav tau kev siv lub sijhawm luv luv (txog {{{}}
Yog qhov muab cov kev qhia ntawm kev kuaj mob
Raws li nws ob qhov sib txawv ntawm kev txawj ntse thiab kev tsis sib haum xeeb, tsis muaj kev sib cav sib ceg, thiab lwm yam kab mob ua kom zoo dua li cov tub ntxhais hluas nyiam
Cim npe nrov: Idra 21 hmoov, cov chaw muag khoom, chaw tsim khoom, Hoobkas, lag luam wholesale, yuav, nqe, loj, loj, rau muag