Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov chaw tsim khoom thiab cov khoom lag luam lactulose qhov ncauj 4618-18-2 hauv Suav teb. Txais tos rau kev lag luam wholesale ntau cov lactulose qhov ncauj ua 4618-18-2 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Lactulose qhov ncauj dawsyog cov kua dej hypertonic ntawm laculose (lub suab hluavtaws rho tawm polymerose ntawm galactose thiab fructose). Nws yog feem ntau tsis muaj xim rau lub teeb xim av ntshiab thiab kua mis nrog lub qab zib me ntsis. Raws li ib qho suab thaj tsis muaj qab hau uas tsis yog nqus tau los ntawm tib neeg txoj hnyuv: So muag cov quav, ua kom nws muaj zog, thiab txhawb cov hnyuv peristalsis, yog li ua tiav cov txiaj ntsig laxative. Nws yog tsuas yog siv los kho cov mob ntev lossis kev quav ntsej, tshwj xeeb yog tsim rau cov poj niam laus, cov menyuam cev xeeb tub, thiab menyuam mos. Ib qho ntxiv, nws tuaj yeem txhawb kev hloov dua siab tshiab ntawm Ammooria hauv cov quav ua ke, yog li nws tseem yog ib qho tshuaj tseem ceeb rau kev kho mob hepatic encephalopathy thiab txo cov ntshav ammonia.
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Tshuaj Cov Qauv |
C12H22O11 |
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Muaj pes tsawg leej |
342 |
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Molecular hnyav |
342 |
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m/z |
342 (100.0%), 343 (13.0%), 344 (2.3%) |
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Kev Ntsuam Xyuas |
C, 42.11; H, 6.48; O, 51.41 |
Lactulose yog ib qho khoom siv nrog ntau lub zog muaj zog, feem ntau yog synthesized los ntawm d - galactose thiab fructose. Hauv qab no yog cov haujlwm tseem ceeb ntawm lactulose:
Txhawb cov hlab ntsha hlwb: lactulose tuaj yeem muag cov quav los ntawm kev nce cov osmotic ntawm cov hnyuv sab nrauv, nyiam cov dej mus rau hauv cov hnyuv. Lub caij no, nws kuj tseem tuaj yeem raug fermented los ntawm cov kab mob tau txais txiaj ntsig hauv kev ua haujlwm rau hlab ntsha
Kev tswj hwm cov plab me microbiota: lacterulose yog ib hom ntawm cov kab mob uas muaj txiaj ntsig zoo, yog li tswj hwm cov plab zom mov microbiotau thiab tswj kev noj qab haus huv.
Txo cov ntshav qab zib:Lactulose qhov ncauj dawsMuaj qis dua qab zib thiab tsis zom lossis tsis zom lossis nqus tau hauv tib neeg lub cev, yog li nws tuaj yeem siv los ua cov khoom qab zib tsawg. Nyob rau tib lub sijhawm, lactulose tuaj yeem txo cov khoom noj glycemic ntawm cov zaub mov thiab pab cov neeg mob ntshav qab zib tswj cov ntshav qab zib tswj ntshav qab zib.
Antioxidant: LACTULOSE muaj qee cov nyhuv antioxidant, uas tuaj yeem tshem dawb radicals hauv lub cev, txo kev ntxhov siab oxidative, thiab cov hlwb los ntawm oxidative kev puas tsuaj. Qhov no pab kom ua kom qeeb cov txheej txheem kev laus thiab tiv thaiv oxidative kev nyuaj siab {}}} tej yam kab mob xws li cov kab mob plawv.
Txhim kho cov hnyuv ib puag ncig: tuaj yeem txo cov kab mob hnyav, txo cov khoom siv ammonia, thiab qis dua lub siab ris nra. Ib qho ntxiv, nws tuaj yeem txhim kho txoj kev thaiv txoj sia ntawm txoj hnyuv, txo qhov nqus cov toxins thiab cov ntxeem tau ntawm pathogens.
Kev kho mob ntxiv rau daim siab tus kab mob: Kev kho mob hepatic enceptopathy los ntawm kev tsim cov protein degrading cov kab mob thiab nqus cov tshuaj lom neeg xws li ammonia. Lactulose plays ib qho tseem ceeb ntawm lub luag haujlwm hauv cov neeg mob hepatic encephanathy, hepatic coma, thiab ua ntej coma.
Lactulose qhov ncauj daws, tseem paub tias yog cuv me, lactrose, lossis cov fraccharide tsim los ntawm -1,4-glycosidic sib khi ntawm galactose thiab fructose. Xyoo 1929, isomerized lactose, tseem hu ua laculose, tau xub tshawb pom hauv cov mis nyuj rhuab. LACTULIBE feem ntau tsis muaj nyob rau hauv qhov thiab yog ib qho khoom siv hluav taws xob ua ke. Nws yog cov hmoov nplej dawb uas yooj yim soluble hauv dej thiab muaj lub qab zib ntau dua li lactose.
1. Tshuaj lom neeg
Cov kab ke no tsuas yog siv sodium hydroxide, poov tshuaj hydroxide, potassium carbonate, thiab tertiary amine ua catalysts, thiab tus nqi hloov zuj zus ntawm lactulose ib puag ncig 20%. Hom kev ua yeeb yam alkaline ntawm cov lactose, ua rau nws ua txhaum thiab tsim cov laculose. Txawm li cas los xij, nws tseem ua rau cov khoom txiav txim siab xws li galactose thiab fructose, uas nyuaj rau cais thiab feem ntau muaj xim tsaus. Kev tsim khoom ntawm {{4 4}} cov khoom lag luam thiab cov pigments tsis tsuas yog txo cov txiaj ntsig, tab sis kuj tseem muaj teeb meem rau kev ua kom huv si thiab crystallization ntawm phoov.
Qhov system no cuam tshuam ntxiv boric acid rau cov tshuaj tiv thaiv. Nyob rau hauv Alkaline tej yam kev mob, boric acid tuaj yeem ua rau laculose borate compilate, hloov chaw sib luag ntawm cov kev tshwm sim ntawm cov kev coj ua kom haum rau laculose ntau lawm. Qhov tsim ntawm cov complexes thiab kev hloov ntawm cov tshuaj tiv thaiv sib npaug sib npaug ntawm cov khoom lag luam rau qhov loj tshaj plaws tau. Tsuas yog ib feem me me ntawm lactrulose yuav hloov mus rau hauv los ntawm {} cov txheej txheem thaum ub cov kev hloov pauv ntawm 70% thiab ntau tshaj ntawm 75%. Tom qab cov kev hloov dua siab tshiab yog ua tiav, lub hom tshuaj tiv thaiv hloov pauv mus rau acidic, thiab cov complex yuav tsum tau tsim lactulose thiab borate. Tom qab tshem lub borate, cov lactulose ntshiab tuaj yeem tau txais. Vim yog qhov tseeb uas borate yog cov khoom lag luam acid tsis muaj zog, xav tsis muaj peev xwm tshem tawm nws hauv qab cov qauv sib pauv, uas tau tshem tawm cov khoom lag luam acid, uas yog kim. Kev npaj ntawm lactulose los ntawm cov kua qaub- cov khoom siv ntawm lactulose, thiab muaj txiaj ntsig zoo rau kev ua kom huv thiab ua kom zoo dua ntawm lactrulose. Qhov no tseem yog txoj kev tseem ceeb rau kev lag luam laculose tam sim no.
Lub tshuab ntawm kev ua ntawm cov kab ke no zoo ib yam li cov boric acid. Cov tshuaj tiv thaiv sopium tuaj yeem dhau los ua cov kev tawm tsam nrog cov tshuaj tua kab mob uas tsim los ntawm isomerization cov tshuaj tiv thaiv, thiab tus ntsuas kev hloov pauv ntawm lacterulose yog li 60%; Txawm li cas los xij, feem ntau, tus nqi ntawm tus nqi ntawm - Cov khoom hauv cov tshuab alkinate yog siab tshaj qhov uas nyob hauv Aluminium ions yog qhov nyuaj dua. In recent years, some scholars have used heterogeneous catalysts including zeolite, sepiolite, eggshell powder, oyster shell powder, etc. to prepare lactulose, and found that a conversion rate of 20% of lactulose can be obtained at a dosage of 15g/L and 90℃; Siv cov hmoov av qe ua ke raws li kev sib cav sib ceg ntawm 18% -21% ntawm lacterulose tau tau tom qab 120 feeb nrog kev siv tshuaj ntawm 12G / l. Txawm hais tias catalysts xws li Zeolite, sepiolite, qe plhaub hmoov, thiab oyster plhaub hmoov ntau rau lactulose, lawv nyob hauv lub xeev ruaj khov thiab raug tshem tawm yooj yim los ntawm kev pom. Yog li ntawd, kev npaj ntawm lactrose siv heterogeneous catalysts muaj peev xwm muaj peev xwm txhim kho.
2. Kev cai lij choj lom neeg
Enzyymatic txoj kev yog txoj kev tseem ceeb rau kev tsimLactulose qhov ncauj dawsLos ntawm kev siv roj ntsha, thiab cov enzymes siv feem ntau -} galactosidase. Nws cov ntsiab cai yog rau hydrolyze lactose rau hauv galactoss thiab hloov galactosidase, thiab hloov galactosidase, thiab hu ua {- D -}} galactosyllassact qhov kev ua si, tab sis kuj muaj qhov kev ua haujlwm siab hauv hydractose kev ua si nyob rau hauv kev hloov galactose kom muaj recuctors. Cov kev tshawb fawb thaum ntxov tau pom tias lub chaw ua haujlwm ntawm {}} pawg ntawm cov pab pawg ntawm cov kab ke thiab cov pab pawg ua haujlwm tseem ceeb hauv kev ua haujlwm ntawm cov lactose los ntawm {}}} galactosidase. Nws yog speculated hais tias cov neeg Sulphur pab pawg tuaj yeem ua raws li cov pa hluav taws xob dav hlau rau cov pa roj av ntawm cov pa roj molyen Tom qab pab pawg imidazole yog cleaved, cov thiol anion rho tawm ib qho proton los ntawm dej molecule, sib sau}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} Xws li cov kab mob acids lactic, bacillus coli, Streptococilus thermophilus, thiab roj ua cov kab mob hnyuv hnyuv; Aspergillus eyzae, aspergillus niger, ryukyu aspergillus, penicillium flavum, hluav taws xob aspergillus, thiab lwm yam hauv fungi; Crispy Walled Kruve cov poov xab, lactic acid kruve cov poov xab, tropida, thiab lwm yam hauv cov poov xab; Streptomyces coelicolor thiab lwm yam kev ua yeeb yam - galactosidase. Vim yog cov kabmob txheeb raws roj ntsha ntawm kev loj hlob sai thiab cov metab graphisms ntawm cov microorganisms tau sib piv ntawm cov kab mob me ntawm cov lej muaj nuj nqis; Cov kev lag luam enzyme feem ntau yog feem ntau yog qhov kev nyab xeeb tshaj plaws, ua raws li los ntawm Aspergillus Niger. Ntawm tam sim no, vim qhov kev ua haujlwm tsawg ntawm {21} galactosidase hauv transglycosidge thiab kev hloov pauv ntawm biological hauv kev npaj lactulose txwv. Qee cov kws tshawb fawb nyob hauv tsev thiab txawv teb chaws tau tshawb nrhiav cov microbial transain nrog kev ua haujlwm siab transglycosylation ua si ntau li ntau tau. Siv tus cwj pwm hloov pauv hloov kho cua sov- tiv taus lactase, lactose thiab fructose thiab fructose tau siv los tsim 50mg / mL lactulose tom qab 6 teev ntawm cov tshuaj tiv thaiv ntawm 80 degree. Vim yog qhov tseeb uas enzymatic npaj ntawm lactulose tuaj yeem kov yeej cov qauv tshuaj, thiab cov txiaj ntsig siab ntawm cov txheej txheem sib cais, nws muaj cov kev sib cais thiab cov tswv yim muaj zog. Qhov no yog ib qho tseem ceeb rau kev txhim kho yav tom ntej ntawm kev npaj lactulose.
Lactulose qhov ncauj daws, tseem paub tias yog cais lossis laciological ua haujlwm xws li kev tswj hwm plab me microbiota, txhim kho cov metabolism, thiab txhim kho cov metabolism. Nws kuj tseem tuaj yeem txo cov ntshav ammonia thiab raws plab, thiab siv rau kev tiv thaiv thiab kho cov kab mob ntawm cov leeg. Hais txog cov zaub mov, nws tuaj yeem siv los ua qhov qis calorie sweetener thiab ua haujlwm zaub mov ntxiv. Nws yog ib qho kev ua haujlwm oligosacinta uas tuaj yeem siv rau tshuaj thiab khoom noj. Nyob rau hauv xyoo tsis ntev los no, nws tau siv dav hauv daim teb thiab kev noj qab haus huv.
Txhua txhua xyoo, lub ntiaj teb tau txais 4 lab tons ntawm cov lactose los ntawm cheese ntau lawm, tab sis tsuas yog 25% ntawm nws tuaj yeem siv ntxiv. Qhov seem 3 lab tons ntawm lactose yog nkim thiab ua cov teeb meem papution ib puag ncig. Ntxiv mus, kwv yees li 70% ntawm cov neeg hauv ntiaj teb muaj cov teeb meem tsis txaus, uas tuaj yeem ua rau cov teeb meem plab zom mov tom qab siv lactose. Qhov txiaj ntsig zoo ntawm cov lactose tau dhau los ua cov teeb meem maj uas yuav tsum tau daws. Qhov tshwm sim ntawm lactrose tau ua tiav daws cov teeb meem no. Cov neeg hloov mus rau lactulose los ntawm kev txwv thiab lwm txoj kev yuav tsis tuaj yeem siv tau, thiab tsis txhob siv cov tshuaj pleev tsis zoo rau hauv ib puag ncig, uas tuaj yeem ua rau ib puag ncig cov pa paug thiab cov chaw pov tseg.
Ua tsaug rau nws cov xeeb ceem zoo heev ntawm lub cev thiab ib puag ncig, lacreulose tau nce zuj zus los ntawm cov tuam txhab hauv cov lag luam biopharmaceutical thiab zaub mov noj. Nws tau siv dav hauv kev kuaj mob hauv lub vijtsam, thiab hauv kev lag luam thiab khoom tsiaj ua khoom noj khoom haus noj qab haus huv. Tam sim no, lactulose phoov yog siv los ua tshuaj nyob hauv kev ua lag luam los kho ntau yam kab mob plab thiab mob hepatic encephalitis. Nws kuj yog siv nyob rau hauv kev lag luam khoom noj hauv Nyij Pooj, xws li cov zaub mov ua haujlwm.
Qhov ob tug loj tshaj plaws ntawm lactulose hauv ntiaj teb yog lub tuam txhab Dutch solvay thiab lub tuam txhab Japanese Morinaga mis los. Solvay yog qhov chaw ua haujlwm ntxov tshaj plaws hauv ntiaj teb kom koom rau hauv laculose ntau lawm, nrog ib lub keeb kwm ntau lawm ntawm 50 xyoo thiab kev lag luam sib koom ntawm 50%. Nws cov khoom lag luam yog siv nyob rau hauv kev lag luam kev lag luam kws tshuaj thiab muaj ob lub ntiaj teb lactulose ntau lawm cov tuam txhab hauv Tebchaws Netherlands thiab Canada; Senyong Cov tuam txhab ua haujlwm Senyong tsuas yog siv cov lactrose rau kev lag luam khoom noj khoom haus thiab kev lag luam tsiaj.
Lub ntiaj teb txhua xyoo thov rau kev laculose hauv kev kho mob yog li 6000 tons, tab sis txhua xyoo kev phatulose tsuas yog 27 tons. Tuam Tshoj tau pib lig nyob rau hauv kev tshawb fawb thiab kev tsim cov lactulose, uas tseem tso siab rau txoj kev tshuaj lom neeg thiab tsim cov kua txiv lactulose qis dua. Medecinal qib siab - Purity laculose tseem tso siab yuav luag tag nrho ntawm cov khoom lag luam. Kev tsim lactulose hauv Suav pib kuj lig thiab dhau lawm thiab tseem tsis tau muaj loj- nplai lactulose ntauenerprose kev lag luam.
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