Mupirocin hmoov, tseem hu ua pseudomonas acid lossis moxorubicin, yog cov tshuaj tua kab mob feem ntau siv los kho cov kab mob ntawm daim tawv nqaij los ntawm gram- zoo cocci. CAS 12650-69-0, Molecular formula C26H44O9, molecular yuag 500.622 g/mol, feem ntau muaj nyob rau hauv daim ntawv thiab tuaj yeem ua dawb los yog tawm dawb crystals. Nws muaj qee yam solubility hauv dej thiab feem ntau yog cov khoom siv hydrophilic xws li polyethylene glycol, uas pab nrog kev faib tawm thiab kev nqus ntawm mupirocin ntawm daim tawv nqaij. Nws yog ib qho zoo tshaj plaws ntawm daim tawv nqaij tiv thaiv kab mob kev npaj, launched los ntawm GlaxoSmithKline nyob rau hauv lub lag luam lub npe "Bactroban" nyob rau hauv 1985. US FDA tau pom zoo cov tshuaj rau kev ua lag luam nyob rau hauv lub tebchaws United States nyob rau hauv 1987, thiab Tuam Tshoj tau pom zoo rau zus tau tej cov tshuaj los ntawm Sino American Square Pharmaceutical nyob rau hauv 1993. Feem ntau yog siv rau kev tiv thaiv thiab kev kho mob ntawm daim tawv nqaij cov kab mob xws li cov kab mob Gramci. raws li pustules, boils, folliculitis, thiab lwm yam kab mob ntawm daim tawv nqaij xws li eczema, ulcers, thiab raug mob. Lub ntsiab mechanism ntawm antibacterial nyhuv yog inhibit protein synthesis nyob rau hauv cov kab mob.
|
|
|
|
Tshuaj Formula |
C26H44O9 |
|
Exact Mass |
500.30 |
|
Molecular Luj |
500.63 |
|
m/z |
500.30 (100.0%), 501.30 (28.1%), 502.31 (2.7%), 502.30 (1.8%), 502.31 (1.1%) |
|
Elemental Analysis |
C, 62.38; H, 8.86; O, 28.76 |
Mupirocin hmoov, tseem hu ua Pidebung ointment, yog cov tshuaj tua kab mob tshuaj pleev ib ce nrog dav -spectrum antibacterial kev ua haujlwm. Nws tsuas yog inhibits cov kab mob protein synthesis, yog li tiv thaiv kab mob loj hlob thiab kev loj hlob. Mopirocin muaj cov tshuaj tua kab mob muaj zog rau ntau yam kab mob Gram zoo thiab qee cov kab mob Gram tsis zoo, xws li Staphylococcus aureus, Streptococcus, Escherichia coli, thiab lwm yam. Raws li dav -spectrum tshuaj tua kab mob nrog cov tshuaj tua kab mob tseem ceeb, nws yog dav siv rau kev kho mob thiab tiv thaiv ntau yam kab mob los ntawm cov kab mob.
Pustular rwj:
Pustular ulcer yog kab mob ntawm daim tawv nqaij purulent los ntawm Staphylococcus aureus. Mopirocin ointment tuaj yeem siv ncaj qha rau thaj chaw cuam tshuam, tua cov kab mob, txo qhov mob thiab mob, txhawb nqa pustule regression thiab kho qhov txhab.
Folliculitis:
Folliculitis yog ib qho mob purulent ntawm cov hauv paus plaub hau thiab cov ntaub so ntswg ib puag ncig, feem ntau tshwm sim los ntawm kev kis tus kab mob Staphylococcus aureus. Mopirocin tshuaj pleev tuaj yeem nkag mus tob rau hauv cov hauv paus plaub hau, tua cov kab mob, txo qhov mob, thiab txhawb kev txhim kho kab mob.
o:
o yog ib qho mob suppurative mob ntawm cov hauv paus plaub hau thiab lawv cov ntaub so ntswg ib puag ncig, feem ntau tshwm sim los ntawm tus kab mob Staphylococcus aureus. Mopirocin ointment tuaj yeem txo qhov mob thiab o ntawm lub plab, txhawb cov kua paug tawm thiab kho qhov txhab.
Paronychia:
paronychia yog ib qho mob purulent ntawm cov ntaub so ntswg ncig ntawm cov rau tes, feem ntau tshwm sim los ntawm kev kis tus kab mob Staphylococcus aureus. Mopirocin tshuaj pleev tuaj yeem nkag mus tob rau hauv cov ntsia hlau zawj, tua cov kab mob, txo qhov mob thiab mob, thiab txhawb kev kho qhov txhab.
Eczema complex nrog kab mob:
Eczema yog ib hom kab mob ntawm daim tawv nqaij, thiab thaum ua ke nrog cov kab mob, tus mob yuav ua rau tsis zoo ntxiv. Mopirocin ointment tuaj yeem tua cov kab mob hauv eczema nyuaj nrog kev kis kab mob, txo qhov mob thiab khaus, thiab txhawb kev daws teeb meem ntawm eczema.
Hlawv qhov txhab kab mob:
Tom qab qhov kub hnyiab, qhov txhab ua rau muaj kab mob, uas tuaj yeem ua rau tus mob hnyav dua. Mopirocin ointment tuaj yeem tua cov kab mob ntawm qhov txhab hlawv, tiv thaiv kab mob, thiab txhawb kev kho qhov txhab.
Kev phais mob incision:
Tom qab kev phais, qhov chaw incision yog nquag mus rau kab mob, ua rau tsis zoo qhov txhab. Mopirocin ointment tuaj yeem siv los tiv thaiv kev kis kab mob thiab kho kev phais mob, txhawb kev kho qhov txhab.
4. Kev kho mob ua pa
Mopirocin tuaj yeem siv tsis tau tsuas yog rau kev kho mob thiab tiv thaiv kab mob ntawm daim tawv nqaij, tab sis kuj rau kev kho mob ntawm qee yam kab mob ua pa. Txawm hais tias nws tsuas yog siv los kho cov kab mob ntawm daim tawv nqaij, qee zaum, xws li kab mob ua pa sab saud, kab mob ua pa hauv qab, thiab lwm yam, mupirocin tuaj yeem siv rau qhov ncauj lossis tso rau hauv kev kho mob ntawm cov kab mob ua pa los ntawm cov kab mob rhiab heev. Txawm li cas los xij, nws yuav tsum raug sau tseg tias daim ntawv thov ntawm mopirocin hauv kev kho cov kab mob ua pa yog qhov txwv thiab yuav tsum tau muaj kev taw qhia los ntawm kws kho mob.
Kev npaj ntawm daim tawv nqaij ua ntej kev phais
Ua ntej kev phais, kev siv tshuaj pleev mupirocin rau ntawm daim tawv nqaij ntawm qhov chaw phais tuaj yeem txo cov kab mob ntawm daim tawv nqaij thiab txo qhov kev pheej hmoo ntawm kev kis mob tom qab phais. Daim ntawv thov no tau txais kev lees paub dav dav thiab suav tias yog ib qho txiaj ntsig zoo ntawm kev tiv thaiv kab mob ntawm qhov chaw phais.
Kev tiv thaiv kab mob hauv qhov txhab hlawv
Rau cov neeg mob kub hnyiab, siv tshuaj pleev mupirocin rau lub qhov txhab kub hnyiab tuaj yeem tua cov kab mob ntawm lub qhov txhab, tiv thaiv kev kis kab mob, thiab txhawb kev kho qhov txhab. Daim ntawv thov no tseem ceeb heev rau kev kho mob thiab rov kho cov neeg mob kub hnyiab.
Lwm yam kev siv
1. Kho cov tawv nqaij khaus
Mopirocin ointment muaj cov tshuaj tiv thaiv - mob thiab tiv thaiv khaus khaus, uas tuaj yeem txo cov tsos mob khaus los ntawm kab mob ntawm daim tawv nqaij. Rau qee yam kab mob ntawm daim tawv nqaij xws li eczema thiab urticaria, mupirocin ointment kuj tuaj yeem muab qee yam kev pab. Daim ntawv thov no tseem ceeb heev rau kev txhim kho lub neej zoo thiab kev nplij siab ntawm cov neeg mob.
2. Moisturize ntawm daim tawv nqaij
Mopirocin ointment tuaj yeem moisturize ntawm daim tawv nqaij thiab txo cov tsos mob xws li dryness thiab flaking.
Mopirocin ointment muaj qee yam kev kho mob rau cov kab mob ntawm daim tawv nqaij qhuav xws li tes thiab ko taw tawg, cheilitis, thiab lwm yam.
3. Adjuvant therapy
Qee zaum, mupirocin tuaj yeem siv los ua cov tshuaj kho mob ntxiv. Piv txwv li, hauv kev kho mob ntawm qhov chaw mos, mupirocin tuaj yeem siv los ua cov tshuaj kho mob ntxiv los pab txo cov tsos mob thiab txhawb kev txhim kho ntawm tus mob. Txawm li cas los xij, nws yuav tsum tau muab sau tseg tias mupirocin tsis yog qhov kev kho mob tseem ceeb rau qhov chaw mos, thiab nws txoj kev ua tau zoo thiab kev nyab xeeb yuav tsum tau soj ntsuam raws li kev qhia ntawm tus kws kho mob.
Lub ntsiab mechanism ntawm cov nyhuv antibacterial ntawmmupirocin hmoovyog cov txheej txheem nyuaj thiab nyuaj, uas feem ntau ua tiav cov kab mob bactericidal lossis bacteriostatic los ntawm inhibiting cov synthesis ntawm cov kab mob proteins. Cov hauv qab no yog cov lus piav qhia ntxaws txog qhov mechanism:
Mupirocin yog ib hom tshuaj tua kab mob uas muaj dav -spectrum antibacterial activation. Nws los ntawm ib yam khoom uas tsim los ntawm kab lis kev cai nruab nrab ntawm Pseudomonas fluorescens, uas yog Pseudomonas A. Cov tshuaj tua kab mob no tuaj yeem ua rau muaj cov kab mob tua kab mob ntawm qhov tsis tshua muaj siab, thaum nws tuaj yeem ua rau cov kab mob bactericidal ntawm qhov siab.
Cov tshuaj tua kab mob ntawm mupirocin feem ntau yog ua tiav los ntawm kev thim rov qab khi nrog isoleucine hloov RNA (tRNA) synthase. Cov txheej txheem no tuaj yeem muab faib ua cov kauj ruam hauv qab no:
Kev khi nrog cov enzymes: Mopirocin tuaj yeem xaiv khi rau isoleucine hloov RNA synthase hauv cov kab mob hlwb. Qhov kev khi no thim rov qab, txhais tau hais tias nyob rau hauv cov xwm txheej tsim nyog, mupirocin tuaj yeem cuam tshuam los ntawm enzyme.
Tiv thaiv kev nkag mus ntawm isoleucine: Los ntawm kev khi rau isoleucine hloov RNA synthase, mupirocin tuaj yeem tiv thaiv kev nkag mus ntawm isoleucine. Isoleucine yog ib qho tseem ceeb amino acids rau cov kab mob protein synthesis, yog li ntawd, tiv thaiv nws infiltration yuav ncaj qha cuam tshuam rau cov kab mob protein synthesis.
Suspension ntawm protein synthesis: Vim tsis muaj isoleucine, cov synthesis ntawm cov protein uas muaj isoleucine nyob rau hauv cov kab mob hlwb yuav raug ncua. Thaum lub sij hawm tus txheej txheem no, mupirocin yeej exerts nws antibacterial nyhuv los ntawm kev cuam tshuam cov kab mob metabolic dab.
Mopirocin muaj cov tshuaj tua kab mob rau ntau yam kab mob, tshwj xeeb tshaj yog muaj kev cuam tshuam rau ntau yam gram -cov cocci zoo cuam tshuam rau cov kab mob ntawm daim tawv nqaij, xws li Staphylococcus thiab Streptococcus. Tsis tas li ntawd, nws kuj muaj qee yam tshuaj tua kab mob rau qee yam kab mob Gram tsis zoo xws li Escherichia coli, Haemophilus influenzae, thiab Neisseria gonorrhoeae. Txawm li cas los xij, nws tsis nkag siab rau feem ntau cov kab mob anaerobic thiab cov tawv nqaij microbiota.
Raws li nws cov tshuaj tua kab mob thiab spectrum, Mopirocin feem ntau yog siv los kho cov kab mob ntawm daim tawv nqaij los ntawm ntau yam kab mob, tshwj xeeb tshaj yog Gram zoo cocci, xws li pustules, boils, folliculitis, thiab lwm yam. Tsis tas li ntawd, nws kuj tseem siv tau rau kev kho mob ntawm cov kab mob thib ob raws li eczema, dermatitis, ntau yam kab mob thiab ulcers.
Kev piav qhia ntxaws txog cov teebmeem pharmacological
Cov tshuaj no, raws li ib tug tshuaj tua kab mob, yog los ntawm ib tug tshwj xeeb tshuaj uas tsim nyob rau hauv lub kab lis kev cai nruab nrab ntawm Pseudomonas fluorescens thiab yog hu ua Pseudomonas A. Nws tshwj xeeb antibacterial mechanism nyob rau hauv nws muaj peev xwm mus reversibly khi nruj nreem rau lub isoleucine hloov RNA (tRNA) synthase nyob rau hauv cov kab mob hlwb. Cov txheej txheem khi no tsis tsuas yog tiv thaiv kev nkag mus zoo ntawm isoleucine, ib qho tseem ceeb amino acid, tab sis tseem cuam tshuam txoj kev sib txuas ntawm cov protein uas muaj isoleucine hauv cov hlwb, yog li ua tiav cov kab mob bactericidal lossis bacteriostatic los ntawm cov kab mob.
Nws yog ib qho tsim nyog sau cia tias cov tshuaj no tuaj yeem nthuav tawm cov kab mob tseem ceeb ntawm qhov tsis tshua muaj siab, thiab thaum lub concentration nce, nws tuaj yeem ua rau muaj zog bactericidal. Qhov kev siv tshuaj tiv thaiv kab mob no ua rau cov tshuaj no hloov tau yooj yim thiab siv tau zoo hauv kev kho mob ntawm daim tawv nqaij.
Nyob rau hauv cov nqe lus ntawm antibacterial spectrum, cov tshuaj no nthuav dav rhiab heev rau ntau yam kab mob. Tshwj xeeb tshaj yog rau gram-cov cocci zoo muaj feem cuam tshuam nrog cov kab mob ntawm daim tawv nqaij, xws li Staphylococcus thiab Streptococcus, cov tshuaj no nthuav tawm qhov rhiab heev. Tsis tas li ntawd, rau cov tshuaj -resistant Staphylococcus aureus, cov tshuaj no kuj muaj cov tshuaj tua kab mob tseem ceeb, uas tseem ceeb heev rau kev kho cov kab mob ntawm daim tawv nqaij los ntawm cov tshuaj tiv thaiv kab mob - cov kab mob.
Tib lub sijhawm, qhov nomupirocin hmoovkuj muaj qee yam tshuaj tua kab mob rau qee yam kab mob gram-cov kab mob tsis zoo, xws li Escherichia coli, Haemophilus influenzae, thiab Neisseria gonorrhoeae. Txawm li cas los xij, rau feem ntau cov kab mob anaerobic thiab ib txwm tawv nqaij microbiota, qhov rhiab heev ntawm cov tshuaj no kuj tsawg, uas yuav pab txo qis kev cuam tshuam ntawm daim tawv nqaij microbiota thiab txo qhov kev pheej hmoo ntawm kev tsis zoo.
Tsis tas li ntawd, kev sim hauv vitro tau pom tias qhov zaus ntawm cov tshuaj - cov tshuaj tiv thaiv kab mob tshwm sim los ntawm cov tshuaj no tsawg heev. Qhov no txhais tau hais tias thaum lub sijhawm kho, qhov muaj peev xwm ntawm cov kab mob txhim kho cov tshuaj no kuj yog me me, yog li ua kom lub sijhawm ntev - kev ua tau zoo thiab kev nyab xeeb ntawm cov tshuaj no hauv kev kho mob ntawm daim tawv nqaij. Cov tshuaj no tau dhau los ua ib qho kev xaiv zoo tshaj plaws rau kev kho cov kab mob ntawm daim tawv nqaij vim nws cov tshuaj tiv thaiv kab mob tshwj xeeb, cov kab mob tua kab mob dav dav, kev ua haujlwm ntawm cov kab mob muaj zog, thiab cov tshuaj tsis tshua muaj tshwm sim - cov tshuaj tiv thaiv kab mob. Txawm li cas los xij, thaum siv cov tshuaj no, nws tseem yuav tsum tau ua raws li tus kws kho mob cov lus qhia, ua tib zoo saib xyuas cov tshuaj ntau npaum li cas, txhawm rau kom ua tiav nws cov txiaj ntsig zoo thiab txo qhov kev pheej hmoo ntawm kev phiv tshuaj.
FAQ
Mupirocin tshuaj pleev siv rau dab tsi?
Mupirocin tshuaj pleev ib ce yog siv los kho qhov mob thib ob ntawm daim tawv nqaij raug mob vim yog cov kab mob tshwj xeeb. Mupirocin tshuaj pleev yog sivkho impetigo. Cov tshuaj no ua haujlwm los ntawm kev tua cov kab mob lossis tiv thaiv lawv txoj kev loj hlob. Cov tshuaj no tsuas muaj nyob nrog koj tus kws kho mob cov tshuaj.
Yuav ua li cas yog tias koj muab mupirocin rau ntawm qhov txhab qhib?
Qhov kev pheej hmoo uas mupirocin tau nkag mus rau hauv lub cev thiab ua rau C. Cov kab mob sib txawv ntau dua yog tias cov tshuaj siv rau ntawm daim tawv nqaij puas. Tus kab mob no tuaj yeem kis tau zoo heev, ua rau raws plab, thiab ua rau lub neej - hem lub cev qhuav dej.
Puas yog mupirocin tsuas yog neosporin?
Mupirocin yog tshuaj tua kab mob uas tuaj yeem ua tshuaj pleev thiab tshuaj pleev. Cov kws kho mob tau sau nws los kho qee yam kab mob ntawm daim tawv nqaij.Neosporin thiab bacitracin yog cov tshuaj tua kab mob uas koj tuaj yeem yuav hauv lub txee yam tsis tas yuav tshuaj.. Lawv tuaj raws li cream thiab tshuaj pleev.
Kuv puas tuaj yeem thov mupirocin rau ntawm kuv lub ntsej muag?
Yog lawm, koj tuaj yeem siv mupirocin rau ntawm koj lub ntsej muag. Tab sis tsis txhob siv cov tshuaj nyob ze koj ob lub qhov muag. Qhov no pab tiv thaiv kev ua xua. Yog tias koj tau txais mupirocin hauv koj ob lub qhov muag, ntxuav lawv nrog dej tam sim ntawd.
Qhov twg koj yuav tsum tsis txhob siv mupirocin?
Medicianz MUPIROCIN Ointment yuav tsum tsis txhob siv los kho cov kab mob hauv lossis ze ntawm lub qhov muag, qhov ntswg (hauv cov menyuam mos) lossis qhov ncauj. Yog tias Medicianz MUPIROCIN Ointment yog siv rau lub qhov muag, ntxuav lub qhov muag kom huv si nrog dej.
Cov tshuaj pleev zoo tshaj plaws rau cov kab mob ntawm daim tawv nqaij yog dab tsi?
Cov tshuaj pleev no tuaj yeem siv ncaj qha rau ntawm daim tawv nqaij thiab pab tiv thaiv thiab kho cov kab mob ntawm daim tawv nqaij me me ntawm kev txiav me me, abrasions, scrapes, thawj -℃kub hnyiab thiab stitched phais qhov txhab.NEOSPORIN®, POLYSPORIN®, thiab Bacitracinyog peb hom tshuaj tua kab mob uas nrov tshaj plaws
Cim npe nrov: mupirocin hmoov cas 12650-69-0, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom