Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov khoom lag luam ntawm Tetravisc ua haujlwm 94-24-6 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale loj zoo tetravisc ua haujlwm 94-24-6 kev muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Khoom sivCAS 94-24-6. Ib qho ntxiv, nws tseem yog lwm lub npe rau tetracaine, tetrakaine, pontocaine. Tetracaine yuav detracaine yuav decompose hauv qab oxidative cua sov, kev ua co2thiab nitrides. Thawj qhov kev txiav txim siab pib yog 285℃C. Nws yog ib qho kev txiav txim siab vim huab cua, thiab av noo, yog li nws yog qhov tsim nyog los saib xyuas txij nkawm thaum siv thiab siv. Cov metabolism ceev hauv lub cev qeeb thiab yuav nthuav tawm hauv lub cev. Kev siv ntev ntev ntawm cov koob tshuaj loj yuav ua rau Hepatotoxicity lossis Neurotoxicity. Kev ua kom tau siab tshaj plaws yog 0.5%. Tom qab nqus tau ntawm daim tawv nqaij thiab cov plaub hau nyias nyias, nws yuav dhau metegolism thiab rub nws cov kev cuam tshuam hauv lub cev. Lub sijhawm zoo yog 2-4 teev. Zuag qhia tag nrho, tetracaine yog ib qho kev tshuaj loog hauv zos nrog kev ruaj ntseg tsis zoo, yog li ceev faj thiab ua raws li cov cai kev nyab xeeb yog tsim nyog thaum siv.
Pharmacological yam ntxwv:
Tshuaj loog Anesthicic:
Lub ntsiab muaj nuj nqi ntawmKhoom sivyog inhibit lub cooj ua hauj lwm ntawm cov leeg ua haujlwm ntawm cov hlab ntsha ntawm cov tshuaj loog, ua tiav kev ua kom loog, kev txhaj tshuaj mob, thiab txo kev hloov pauv.
Vasodilatory effect:
Tetracaine tuaj yeem tsim cov vasyodation los ntawm kev sib xyaw ua ke ntawm angiotensin, yog li txo cov ntshav siab thiab txo qis cov ntshav siab thiab txo cov ntshav siab.
Cov nyhuv tua kab mob:
Tetracaine muaj qee yam cuam tshuam ntawm cov tshuaj tua kab mob hauv ib qho kev siv tshuaj thiab muaj txiaj ntsig tawm tsam cov kab mob, fungi, thiab cov kab mob.
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Synthesis txoj kev catalyzed los ntawm polytetrosauruoroethylene:
Tsis ntev los no, ib tug neeg tau tshaj tawm txoj kev catalytic rau ncaj qha synthesizingKhoom sivCov. Tus yuam sij rau hom no yog siv polytetrosraethylene raws li catalyst kom hnov kom muaj 2- (4-aminobenyl) phenol nrog benzoyl chloride thiab isopropyl carbamate. Tetracaine nrog cov txiaj ntsig ntawm 90% tuaj yeem tau txais tsis pub dhau 3 teev. Qhov zoo dua ntawm cov qauv no nyob hauv nws cov kauj ruam yooj yim, siab tawm los, thiab nrawm nrawm, uas tuaj yeem txo tus nqi.
Cov kauj ruam ntxaws ntxaws thiab coj cov tshuaj sib txig sib luag ntawm cov qauv saum toj no yog raws li hauv qab no:
Cov kauj ruam ntxaws:
Cov Khoom Siv Khoom Raw:
Npaj 2- (4-aminobenyl) phenol, benzoyl chloride, thiab isopropyl carbamate los xyuas lawv txoj kev huv thiab dryness. Zom lub PTFE catalalyst mus rau hauv cov hmoov daim ntawv kom tau siv nws cov nyhuv catalytic.
Npaj kev tshaj lij hlab:
{{0 {{}} Xaiv cov kev sib tw tsim nyog, xws li ib puag ncig hauv qab lossis peb lub caj dab
-}}}}}}} Ntxiv PolytetraTrene catalyst mus rau lub nkoj uas tsim nyog thiab yaug nrog cov roj ntsha uas tsim nyog
Cov khoom siv nyoos ntxiv thiab cov tshuaj tiv thaiv pib:
{{0-}}}}}}}}} {-aminobenzyl) Penol nyob rau hauv tus nqi tsim nyog (xws li maj mam ntxiv rau kev tawm tsam hlab ntsha.
{{0- Tom Qab, Benzoyl Chloride thiab Isopropyl Carbamate tau tseem yaj nyob rau hauv cov kuab tshuaj organic thiab ua ntu zus mus rau lub nkoj tawm tsam.
{{0- thaum cov txheej txheem ntawm kev ntxiv cov ntaub ntawv raw, khaws cov tov khoom rau kom ntseeg tau tias nws cov khoom siv sib xyaw.
Cov txheej txheem tshuaj tiv thaiv kev tswj hwm:
- Tswj cov tshuaj tiv thaiv kub nyob rau hauv ib qho kev kub, feem ntau los ntawm chav kub mus rau kev kawm me ntsis rau cov tshuaj tiv thaiv.
{{0} Kev saib xyuas cov txheej txheem tshuaj tiv thaiv los ntawm kev txheeb xyuas cov twj tshuaj xyuas los ntawm kev siv cov khoom siv ntawm reactants thiab ntau tiam cov khoom lag luam.
Qhov kawg ntawm cov tshuaj tiv thaiv thiab kho cov khoom:
-}}}}}}}}}}}}} Thaum nws nce mus txog lub sijhawm ua ntej (xws li yuav luag 3 teev) lossis thaum yuav luag ua tiav cov khoom siv raw yog kuaj tau.
{{0} Lim cov tshuaj tiv thaiv sib xyaw kom tshem tawm polytetraToroethylene catalyst thiab lwm yam tsis huv.
{{0-}}}}} ine allingual thiab qhuav cov filltrate kom tau txais cov khoom nyoos.
Kawg no
Cov khoom lag luam nyoos yog cov txheej txheem sib cais ntxiv los ntawm kev sib cais thiab xws li crystallization, distillation, lossis chromatographic sib cais) kom tau txais tetaviscograph.
Cov tshuaj tiv thaiv catchalyzed los ntawm polytetrafluoroethylene:
Vim tias lub complex mechanism ntawm polytetrospaethylene raws li catalyst thiab qhov tseeb hais tias nws tseem tsis tau muab cov tshuaj tiv thaiv tseeb thiab hloov chaw nyob. Tab sis nws tuaj yeem ua kom yooj yim rau cov kab zauv hauv qab no los sawv cev rau nws cov nyhuv catalytic:
Catalyst (c2f4) n) {+2-} Am6h {18244n2o2+ lwm yam los ntawm-khoom
Cov kauj ruam tseem ceeb:
Txuj ci tshuaj tiv thaiv ntawm 2- (4-aminobenyl) phenol thiab benzoyl chloride:
2- (4-aminobenyl) Phenol + Benzoyl Chloride → 2- (4-benzoyl aminobenzyl) Phenol + HCL
2 {- (4-belzoylaminoblenthyl) Phorroopyl carbamate → c15h24n2o {}} lwm yam los ntawm-khoom
Kev sib tw kom zoo dua
Qhov zoo ntawm cov txheej txheem no dhau txoj hauv kev yog:
Ruam yooj yim:
Piv rau cov qauv ib txwm muaj, txoj kev no zam cov kauj ruam nruab nrab thiab cov khoom sib cais thiab cov txheej txheem ua kom yooj yim, yooj yim yooj yim rau cov txheej txheem ua haujlwm.
High tawm los thiab muaj txiaj ntsig zoo:
Nyob rau hauv catalytic action ntawm polytetrrafluoroethylene, cov tshuaj tiv thaiv ceev nrawm nrawm thiab cov qoob loo tshaj plaws ntau dua kev ua tau zoo.
Txo Nqi:
Vim cov kauj ruam yooj yim, nrawm nrawm nrawm, thiab muaj txiaj ntsig zoo, cov qauv no tuaj yeem txo cov nqi ntau lawm thiab txhim kho kev nyiaj txiag.
Kev ua phooj ywg ib puag ncig:
Los ntawm kev ua kom zoo cov kev tshwm sim thiab txo cov kev tshwm sim ntawm los ntawm - cov khoom lag luam, cov qauv no yuav pab txo cov pa hluav taws xob ib puag ncig thiab txhim kho cov khoom siv hluav taws xob ib puag ncig thiab txhim kho cov tshuaj lom neeg ntawm cov tshuaj synthesis.
Qhov qauv no ntawm ncaj qha tetracaine siv polytetrrafluoroethylene raws li catalyst zoo li qhov zoo tshaj plaws rau kev ua haujlwm ntawm cov tshuaj schthesis. Txawm li cas los xij, kev tshawb fawb ntxiv thiab sim ua pov thawj xav tau kom tau txais kev nkag siab tob ntawm cov kev tawm tsam thiab ua kom muaj kev cuam tshuam zoo ntawm cov qauv no. Lub caij no, hauv kev siv cov ntawv thov, kev saib xyuas yuav tsum tau them rau cov khoom siv raw, thiab kev tswj hwm ntawm cov tshuaj tiv thaiv ntawm cov tshuaj tiv thaiv thiab qhov zoo ntawm cov khoom.
Synthesis ntawm tetracaine los ntawm hydrogenation txo cov qauv, cov kauj ruam tshwj xeeb yog raws li hauv qab no:
(1) RESE 2-acetoamino 4-Methylfphenol nrog 3-actealloyl chloride hauv chloroform kom tau txais 3- (2-acetoamino 4-methylphenoxy) profionyl chloride.
(2) Cov khoom saum toj no thiab 2-}} penzloc acid kom tau txais}
(3) Cov khoom saum toj no yog hydrogenated thiab txo nrog txhuas oxide magnesium complex thiab ua pob txha actic acid nyob rau hauv lub xub ntiag ntawm isopropanol kom tauKhoom siv.
Cov neeg ua xua rau cov khoom lag luam no tsis pub. Cov neeg muaj kev tsis haum cai loj yuav tsum tsis pub. Kev Txiav Txim Siab, Lub Cev Tsis Txaus, Myasenia Gravis thiab lwm cov neeg mob yog contraindication. Infiltration ntawm cov tshuaj loog hauv zos ua kom zoo nkauj, txhaj tshuaj tiv thaiv thiab lub cev muaj zog yog contraindication. Lub zos tshuaj loog ntawm tetracaine tau ua tiav los ntawm kev cuam tshuam cov kev sib kis ntawm cov hlab ntshav ntawm cov hlab ntsha imactes. Cov hlab ntsha tsis sib haum yog cov teeb liab hluav taws xob uas taug kev raws li lub neuron axon. Cov ntsev ntsev ntawm lub axon yog ib txwm qhib. Thaum lub hlab ntsha tsis sib haum xeeb tshwm sim, sodium ions hla dhau ntawm cov channel, ua rau muaj kev hloov pauv ntawm sab hauv thiab sab nraud ntawm tes, uas nyob rau hauv lem coj mus rau kev sib kis ntawm cov hlab ntsha impulse. Thaum cov hlab ntsha tsis sib haum xeeb mus txog ib lub hlab ntsha synapse, nws tau tshaj tawm cov cim tshuaj lom neeg, uas cuam tshuam nrog cov dej qab zib tom ntej, uas txuas ntxiv mus xa cov paj hlwb impulse. Tetracaine cuam tshuam cov kev sib kis ntawm cov hlab ntsha im impulses los ntawm xaiv inhibiting inhibiting sodium ion raws, yog li ua ib qho tshuaj loog hauv zos.
Dab tsi yog cov kev phiv los ntawm no compound no?
Cov kev mob tshwm sim ntawm cov compound no feem ntau yog koom nrog nws txoj kev nyab xeeb thiab thev lav cov teeb meem hauv kev siv tshuaj kho mob. Cov hauv qab no yog cov ntsiab lus piav qhia ntxaws ntxaws ntawm nws cov kev phiv:
Cov tshuaj hauv zos
Kev tsis haum
Qee tus neeg mob yuav ua tsis haum rau cov duab no, ua kom tawv nqaij liab, khaus, urticaria, thiab lwm yam tsos mob. Thaum muaj mob hnyav, nws kuj tseem tuaj yeem ua rau Anaphylactic poob siab, uas yog lub neej kev phom sij uas yuav tsum muaj kev kho mob sai.
Kev Koom Tes Ua Haujlwm
Vim yog lub hauv paus hauv zos tshuaj loog hauv zos ua rau cov pa hluav taws xob no, xws li kev puas tsuaj hauv zos, xws li cov tawv nqaij necrosis, thiab lwm yam.
Cov kev coj ua
Cov tshuaj tiv thaiv neurological
Tom qab siv cov compound no, qee tus neeg mob yuav muaj cov tshuaj neuralological xws li kiv taub hau, mob taub hau, ntuav, thiab lwm yam tsos mob. Cov tsos mob no feem ntau yog me, tab sis kuj yuav cuam tshuam rau tus neeg mob lub neej thiab ua haujlwm txhua hnub.
Cov Tshuaj Tiv Thaiv Cardiovascular
Muaj qee kis, cov duab no yuav ua rau cov lus teb plawv xws li Tachycardia, Arthythmia, thiab lwm yam.
Kev hloov pauv
Qee tus neeg mob yuav muaj kev mob ua pa xws li ua pa nyuaj thiab laryngeal edema tom qab siv cov compound no. Cov kev tawm tsam no tuaj yeem raug mob rau tus neeg mob lub neej thiab xav tau kev mob kho mob sai thiab thaum muaj xwm ceev.
Lwm sab - cov teebmeem
OtoTOXICITY
Lub sijhawm ntev lossis ntau dhau ntawm qhov sib txuas no yuav ua rau tus neeg mob kev sib hais thiab ua rau cov khoom sib hais ntawm cov pob ntseg. Qhov kev coj ua no feem ntau yog tshwm sim xws li cov tsos mob xws li kev hnov lus ploj thiab tinnitus.
Mob siab puas
Txawm hais tias qhov no sib xyaw ua ke tsuas yog cov kev kho mob kho mob los ntawm kev ua yeeb yam hauv zos, ntev {}} lub sijhawm lossis ntau dhau yuav ua rau lub siab puas. Qhov kev puas tsuaj no yuav nthuav tawm tias cov tsos mob xws li kev ua haujlwm lub siab ua haujlwm thiab lub siab ua kom lub siab enzymes.
Kev sib cuam tshuam yeeb tshuaj
Qhov no sib xyaw no yuav cuam tshuam nrog lwm cov tshuaj thaum siv ib txhij, ua rau txo cov kev ua tau zoo lossis kev phiv ntau ntxiv. Yog li, thaum siv nws, cov kws kho mob yuav tsum paub txog lwm yam tshuaj lawv tab tom noj tam sim no kom lawv tuaj yeem kho lawv lub hom phiaj kho tshuaj.
Cov kev ceev faj
- Ua ntej siv cov compound no, nws yog ib qho tsim nyog los ua tib zoo to taub txoj kev siv kev siv thiab kev ceev faj ntawm cov tshuaj kom ntseeg tau tias siv tau.
- Yog tias muaj cov tsos mob tsis xis nyob tshwm sim, tsum tsis txhob noj cov tshuaj tam sim ntawd thiab nrhiav kev kho mob.
- Cev xeeb tub thiab lactating poj niam, nrog rau cov neeg mob uas muaj mob siab lossis mob siab, yuav tsum siv cov kev taw qhia ntawm tus kws kho mob.
- Zam kev siv nws ua ke nrog lwm cov tshuaj kom tsis txhob sib cuam tshuam.
Yuav tsum muaj kev ntsuam xyuas dab tsi ua ntej siv cov compound no?
- Xiam Kev Nug Keeb Kwm: Nug seb tus neeg puas muaj keeb kwm ua xua rau cov tshuaj noj kom muaj tshuaj rau cov tshuaj lossis lwm yam loog. Qhov no yog ib qho tseem ceeb heev vim tias muaj kev fab tshuaj uas tuaj yeem yog lub neej ({1}} kev hem.
- Kev kuaj mob hauv zos: Kos rau kis mob, mob, lossis lwm yam kev txawv txav hauv thaj chaw uas cov tshuaj siv. Yog tias cov xwm txheej no muaj nyob, nws yuav tsim nyog kom tau siv lossis coj lwm yam kev ntsuas.
- Tus Neeg Mob Kev Ntsuas: Ntsuas kev saib xyuas kev noj qab haus huv tag nrho ntawm tus neeg mob, suav nrog lub plawv, lub ntsws, thiab cov leeg ntshav. Txawm hais tias cov kev ntsuam xyuas no yuav tsis raug tsim tshwj xeeb rau nws, lawv yog lub hauv paus rau kom ntseeg tau tias cov neeg mob tuaj yeem txuas txoj kev kho mob.
- Tam sim no siv tshuaj yeeb tshuaj STsis siv puab cov tshuaj, tshwj xeeb yog cov uas yuav muaj kev cuam tshuam rau kev ua yeeb yam enseshesia lossis nce txoj kev pheej hmoo ntawm cov kev mob tshwm sim. Qhov no pab cov kws kho mob txiav txim siab seb nws yuav tsum tau kho cov tshuaj noj lossis nqa lwm cov kev tiv thaiv.
- Cov Lus Qhia Kho Mob Ua Ntej: Tseem ceeb tshaj plaws, cov neeg mob yuav tsum ua raws li tus kws kho mob cov lus qhia thiab ua ib qho kev kuaj xyuas lossis kev npaj raws li kws kho mob cov lus qhia
Cim npe nrov: Tetravisc CAS 94-24-6, Cov chaw muag khoom, chaw tsim khoom, Hoobkas, lag luam wholesale, yuav, nqe, loj, loj, rau muag