Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov khoom lag luam thiab cov khoom lag luam ntawm 1,8-naphthalenediol CAS 569-42-6 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale mis muaj txiaj ntsig zoo 1,8-naphthhalenediol CAS 569-42-6 kev muag khoom ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
1,8-naphthhalenediol, tseem hu ua 1,8-dihydroxynthhalene, yog cov organic compound uas feem ntau tshwm li grey dawb tawv hmoov. Nws muaj qee qhov solubility hauv dej thiab yog yooj yim soluble hauv alkaline cov kev daws teeb meem thiab cov organic cov kuab tshuaj. Nws zwm rau chav kawm ntawm phenolic derivatives, nrog cov acidity acidity thiab muaj zog nucleophilicity. Nyob rau hauv Alkaline tej yam kev mob, ua rau hydrogen peroxide tsis zoo ions muaj peev xwm tsim tawm, uas muaj kev sib haum xeeb muaj peev xwm nrog kev hloov pauv hlau. Qhov khoom no muaj cov tshuaj lom neeg muaj kuab lom thiab tuaj yeem siv los ua hluavtaws cyclic tau muab los ntawm 1,8-naphleol los ntawm nws nucleophilicity. Nws kuj tseem tuaj yeem hnov mob nrog cov alkyl electrophilic reagents kom tau txais kev sib raug ether lossis ester organic teb. Nws yog qhov tseem ceeb hauv nruab nrab hauv cov khoom siv hluav taws xob organic, uas tuaj yeem siv los ua hluavtaws ntau yam, xws li Cyclicidal nquag Molecules thiab Cyclic cov tebchaw tau los ntawm 1,8-naphthol. Nyob rau hauv thaj teb tshuaj chemistry, nws tseem muaj qee tus neeg siv tus nqi thiab tuaj yeem siv los siv qee yam tshuaj lossis tshuaj nruab nrab.
Cov ntaub ntawv ntxiv ntawm kev sib txuas lus:
|
Tshuaj Cov Qauv |
C10H8O2 |
|
Muaj pes tsawg leej |
160.05 |
|
Molecular hnyav |
160.17 |
|
m/z |
160.05 (100.0%), 161.06 (10.8%) |
|
Kev Ntsuam Xyuas |
C, 74.99; H, 5.03; O, 19.98 |
|
Melting taw tes |
137-143 Qib |
|
Kub taw tes |
140 Qib (Nias: 10 Torr) |
|
Ceev |
1.33 |
|
Kev Cia |
2-8 degree |
|
|
|
1,8-naphthhalenediol, tseem hu ua 1,8-dhihydroxynthhalene, yog cov organic sib xyaw nrog cov qauv tshuaj tshwj xeeb thiab cov ntawv thov ntau. Cov hauv qab no yuav piav ntau ntxiv ntawm nws cov ntawv thov hauv ntau daim teb thiab tshawb xyuas nws cov kev txhim kho:
1,8-Dihydroxynthhalene muaj ob pab pawg phenhoxyl ntau pab pawg, uas txhim kho nws cov khoom siv hydrogen ntau thiab txhim kho nws cov tshuaj xws li. Nrog nws nucleophilicity, 1,8-dihydroxynthhalene tuaj yeem siv los ua ke ntau yam sib xyaw ua ke los ntawm 1,8-naphthol. Piv txwv li, 1,8-dihydroxynthhalene tuaj yeem hnov mob nrog phosphine trichhloride rau daim ntawv coj ua cov oxygen complexed chlorophosphine compounds. Cov tebchaw tseem ceeb tshaj plaws rau cov khoom siv hauv nruab nrog cev thiab tuaj yeem siv ntau dua los ntawm lwm cov}, 8-dihydrophilic reagents kom tau txais kev sib xyaw etherents lossis ester organic teb. Cov teb no yog ib qho tseem ceeb hauv cov organic synthesis thiab tuaj yeem siv rau kev siv tshuaj ntxiv, cov tshuaj tsw qab, tshuaj tsw qab, thiab lwm yam. Piv txwv li, los ntawm kev tiv thaiv kab ntsig, 1,8-dihydroxynthalene tuaj yeem hloov mus rau Eether Cov Zej Zog nrog cov haujlwm tshwj xeeb; Los ntawm cov tshuaj tiv thaiv esterification, Ester cov lus teb nrog cov qauv kev sib txawv tuaj yeem tau txais. Nws kuj tseem tuaj yeem ua rau cov hws hws uas tsis tuaj yeem, ntxiv rau lwm cov organic sib txuas los tsim cov qauv organic nrog cov qauv txheej txheem tshwj xeeb thiab cov haujlwm tshwj xeeb. Cov lwg me me no muaj cov ntawv thov tseem ceeb hauv cov qauv hauv nruab nrog cev thiab tuaj yeem siv los ua cov ntaub ntawv tshiab, tshuaj, thiab lwm yam.
Kws Tshuaj Kho Mob Hluav Taws Xob
1,8 {{{{4 4}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} Thov siv ua cov tshuaj nruab nrab rau ntau yam tshuaj. Nws cov qauv tshuaj tshwj xeeb thiab cuam tshuam nrog nws los koom nrog hauv cov txheej txheem kev tsim kho ntawm ntau yam tshuaj molecules. Piv txwv li, qee cov tshuaj lwg siv roj nrog cov tshuaj tua kabmob xws li cov tshuaj tua kab mob, thiab antioxidrant muaj cov txheej txheem ntawm 1,8-dhihydroxynthhalene. Los ntawm synthesizing cov tshuaj molecules no muaj 1,8-dihydroxynthhalene, cov kev xaiv tshuaj tshiab tuaj yeem muab rau cov kev tswj hwm uas muaj feem xyuam rau kev tsim kev tshuaj. Cov kws tshawb nrhiav tuaj yeem siv nws cov tshuaj tshwj xeeb tsim kho thiab ua hluavtaws cov qauv tshuaj tshiab uas muaj cov kev ua ub no. Los ntawm kev tshuaj ntsuam thiab ua kom zoo dua cov qauv siv yeeb tshuaj tshiab, muab cov tswv yim thiab cov tswv yim thiab cov qauv kev txhim kho tshiab.
1,8-Dihydroxynthhalene tuaj yeem siv los ua cov khoom ntxiv rau cov khoom siv ua haujlwm los txhim kho lawv cov kev ua tau zoo. Piv txwv li, ntxiv 1,8-dehydroxynthhalene mus txhim kho lawv cov khoom siv hluav taws xob thermal, cov khoom siv tshuab, thiab tshuaj lom neeg ua tsis taus. Tsis tas li ntawd, 1,8-dihydroxynthhalene tuaj yeem ua ke nrog lwm cov pab pawg ua haujlwm los ua cov khoom siv polymer nrog cov haujlwm tshwj xeeb. Cov ntaub ntawv no muaj feem cuam tshuam cov kev cia siab hauv liaj teb xws li hluav taws xob, OptoelectRonics, thiab hnov zoo}, 8-dihydroxyst tau siv los ua synthesize thiab pigments. Nws cov qauv tshuaj tshwj xeeb pub rau nws khi cov chromophores, ua zas xim molecules nrog cov xim qaim thiab cov xim zoo nkauj thiab cov xim zoo nkauj. Cov dyes thiab cov pigments muaj ntau cov kev siv hauv cov ntawv nyeem xws li cov ntawv sau, thiab lwm yam los ntawm cov xim sib txawv thiab cov khoom muaj peev xwm ua tau zoo sib xws.
1,8-naphthhalenediol tseem ua yeeb yam ntawm lub luag haujlwm tseem ceeb hauv cov nroj tsuag
1,8-naphthhalenediolyog cov phenolic phenolic compound nrog cov molecular cov kab mis C10H8o2, tsim los ntawm ob pawg Atoms atoms ntawm cov haujlwm 1 thiab 8 ntawm lub nplhaib naphthalene. Nws cov tshuaj lom neeg suav nrog:
Acidity thiab Nucleophilicity
Lub xub ntiag ntawm cov pawg hydroxyl muab nws cov acidity acidity, uas tuaj yeem tsim cov tsis zoo ions (O ⁻) nyob rau hauv alkaline tej yam kev mob, txhim kho nucleophilicity, thiab koom nrog ntau yam kev tawm tsam.
Muaj peev xwm ua haujlwm
Hydrogen peroxide tsis zoo ions tuaj yeem tsim ruaj ruaj nrog cov neeg sib tw me me, tooj, thiab zinc, thiab zinc, thiab zinc uas tuaj yeem koom nrog hauv kev tswj hwm hlau lossis enzyme kev ua haujlwm hauv Vivo.
Kev xav tau
Raws li nrab nruab nrab, 1,8-dhihydroxynthhalene tuaj yeem siv los ua cov lus qhia txog kev ua txhaum, thiab palmermeopal cp17 analoguan derivatives tau koom nrog synthesis ntawm cov tshuaj tiv thaiv kab mob.
Lub luag haujlwm ntawm cov metabolites hauv cov nroj tsuag tiv thaiv
Nroj tsuag tiv thaiv mathogens thiab cov kab ntawm cov kab ke ntawm cov kab ntawm cov metabolites thib ob xws li phenols, terpenes, thiab alkaloids. Cov metabolites tau muab faib ua ob pawg:
Kev Tiv Thaiv Kev Tiv Thaiv Me
Pre synthesized thiab khaws cia rau hauv cov nroj tsuag, ncaj qha inhibiting pathogens los yog kab.
Ntxias tiv thaiv metabolites
Tshwj xeeb tshaj tawm tom qab kev yuam kev, nrog ntau kev siv nyiaj ntau ntxiv, yog qhov tseem ceeb ntawm cov nroj tsuag tshuaj tiv thaiv.
1,8-dehydroxynthhalene tej zaum yuav yog ua ntej kev tiv thaiv kev tiv thaiv me me metabolites, thiab nws txoj kev tiv thaiv kev tiv thaiv, thiab nws muaj nuj nqi dealense kev sib txuas nrog kev sib txuas nrog cov kev ntsuas metabolism.
Muaj peev xwm lub luag haujlwm ntawm 1,8-dhihydroxynthhalene hauv cov kws muaj txuj ci cog
Raws li ib tug ua ntej rau melanin synthesis, nws txhim kho lub cev lub cev
Fungal Melanin Ntau Lawm: 1,8-dihydroxynthhalene yog ib qho tseem ceeb rau kev sib sau ua ke ntawm Dhnlanin (1,8-Dihydroxynthhalene Melanin). Dim Melanin yog ib qho tseem ceeb ntawm cov phab ntsa ntawm tes ntawm ntau cov pob zeb tawg (xws li UV tiv thaiv thiab enzymatic hydrolysis tsis kam).
Nroj Tsuag Tiv Thaiv Lub Tswv Yim: Nroj tsuag yuav sib tw los yog degrade 1,8-dihydrexynthhalene, thaiv lawv cov pathogenic fungi, thiab tsis muaj zog lawv kis tau. Piv txwv li, melanin degrading enzymes lossis chelating tus neeg sawv cev ua los ntawm cov nroj tsuag tuaj yeem cuam tshuam nrog fungal metabolism.
Cov Ntaub Ntawv Txhawb: Cov kev tshawb fawb tau pom tias cov nroj tsuag ua ke sib xyaw ua ke thaum muaj kab mob thaum muaj kab mob funganin deposition thiab txwv nws cov kev nthuav dav.
Synthesize kho cov kab mob antibacterial molecules kom ncaj qha inhogit pathogens
Dercthesis: 1,8-Dihydroxynthhalene tuaj yeem tsim cov tshuaj tua kab mob naphholehoquinone los ntawm oxidation, kev sib cav, thiab lwm yam kev tawm tsam. Cov derivatives no tuaj yeem ua kev puas tsuaj ntawm tes ntawm lub ntsej muag ntawm tes ntawm tes, inhibit ua pa ntxig, lossis cuam tshuam nrog DNA synthesis.
Cov pov thawj kev sim: Hauv cov kev sim vitro tau pom tias cov kab mob crecheróynthalas muaj cov teebmeem ntawm lub nroog CanderoTus), hais tias lawv tuaj yeem ua lub luag haujlwm zoo sib xws hauv cov nroj tsuag.
Cov koom haum metabolic: sib txuas nrog naphthalene xws li cov qauv (xws li cov kev xav uas 1,8-dihydroxyst ua haujlwm ua ntej rau cov tshuaj tiv thaiv.
Koom tes nrog cog microbe kev sib cuam tshuam thiab tswj cov paib tiv thaiv
Daim paib Kev Ua Haujlwm: 1,8-DihyDRoxynthhalene yuav ua raws li kev piav qhia txog kev piav qhia ntawm cov nroj tsuag tiv thaiv cov noob muaj feem. Piv txwv li, nws cov khoom siv oxidonic tuaj yeem ua kom lub jasmonic acid (ja) lossis salicylic acid (sa) kev txeeb chaw tsis kam tiv taus (SAR).
Microbial ua rau synthesis: kab mob los ntawm pathogenic bacogenia los ntawm cov kab mob hauv plab ntawm 1,8-dhihydroxynthhalene raws li lub teeb liab tiv thaiv hauv zos lossis systemic tiv thaiv. Piv txwv li, cov kab mob rhizosphere tuaj yeem txhawb cov synthesis ntawm phenolic tebchaw hauv cov cag ntoo, txhim kho cov kab mob tsis kam.
Kev Tshawb Nrhiav GAP: tam sim no, tsis muaj pov thawj ncaj qha los qhia txog kev sib txawv ntawm cov khoom siv tshuaj pleev ib ce xws li chlorogenic acid qhia txog qhov ua tau.
Ion Chelation Inhibits Pathogen enzyme kev ua si
Cov khoom lag luam hlau-tiv thaiv: Ntau pathogenic bacteria 'enzymes (xws li as-⁺ ⁺ ⁺, zn ⁺, zn ⁺) kom tau txais lawv cov haujlwm. Lub chaw ua haujlwm muaj peev xwm ntawm 1,8-dihydroxynthhalene yuav ua kom nws tau chelate cov ions thiab inhibit enzyme muaj nuj nqi.
Cov Ntaub Ntawv Tiv Thaiv Hlau: Nroj Tsuag Roj Av (xws li cov kab mob hlau uas tseem ceeb tshaj plaws
Kev sim ua kev sim: hluavtaws hlau chelating cov neeg sawv cev (xws li Edta) yog siv hauv kev ua liaj ua teb kom muaj cov neeg sawv cev (xws li 1,8-dhihdroxynthhalene) tej zaum yuav muaj kev ua haujlwm zoo sib xws.
Synergistic nyhuv nrog lwm cov kws muaj txuj ci
Synergistic nyhuv nrog phenolic tebchaw
1,8-Dihydroxynthhalene yuav cuam tshuam nrog lwm cov phenols (xws li chlorogenic acid thiab tannins) los txhim kho cov kev ua tau zoo. Piv txwv li, phenolic compounds tuaj yeem puas pathogen patogen matogen matoges, thaum 1,8-dihydrexynthhalene derivbatives yuav inhibit me ntsis kev kho lawv.
Compllyllyarity nrog terpenes
Terpenes (xws li phytohormones) feem ntau siv los ua cov tshuaj tiv thaiv kab mob, thaum 1,8 {2} {{{{{{{
Kev sib koom tes nrog kev thaiv lub cev
Los ntawm inhibitive synthesis ntawm cov kab mob melanin los ntawm cov kab mob pathogenic thiab ua haujlwm synetrate cov cav me me xws li Lignin Deposition.
Kev tshawb fawb cov xwm txheej thiab yav tom ntej cov lus qhia
Kev tshawb nrhiav tam sim no
Lub neej muaj sia thiab hluavtaws evhway ntawm 1,8-dhihydroxynthhalene hauv cov nroj tsuag tseem tsis tau paub meej, thiab cov kev tshawb fawb feem ntau tsom rau cov tshuaj lom hluav taws xob lossis hauv cov tshuaj vitro.
Tsis muaj nyob rau hauv Vivo ua haujlwm yam siv tau siv hauv cov nroj tsuag, xws li gene editing thiab metabolomics tsom xam.
Kev Tshawb Nrhiav Yav Tom Ntej
Metabolomics tsom xam: txheeb xyuas cov qauv sib txuam ntawm1,8-naphthhalenediolThiab nws cov derivatives hauv cov nroj tsuag kis tau tus kab mob uas muaj tus kab mob.
Kev Tshawb Fawb Ua Haujlwm Kev Tshawb Fawb: Knockpress Tawm lossis Overxpressing cuam tshuam ntsig txog cov noob hluav taws xob hluavtaws siv tau siv CrisP / Cas9 los soj ntsuam kev hloov pauv hauv kev tiv thaiv phenotypes.
Kev Sib Koom Tes Siv Hluav Taws Xob: Siv poov xab ob lub hybrid lossis txhaj tshuaj tiv thaiv kev txhaj tshuaj, tshuaj ntsuam cov tshuaj tiv thaiv lossis cov pathogen proteins uas khi rau 1,8-dhihydroxynthhalene.
Cim npe nrov: 1,8-naphthhalenediol CAS 569-42-6, cov chaw tsim khoom, chaw tsim khoom, chaw tsim khoom, lag luam, yuav, nqi, loj, rau muag