Zaj tshaj tawm
Peb tsis txhob muab txhua yam tshuaj ntawm piperidine series, txawm tias muaj peev xwm tau txais piperidine lossis piperidone chemcials!
Tsis muaj teeb meem nws txwv lossis tsis! Peb tsis muab!
Yog tias nws nyob hauv peb lub Webiste, nws tsuas yog rau xyuas cov ntaub ntawv ntawm cov tshuaj sib txuas.
Mar. 25 2025
1-} tert-butyl {2}}}}}}}} dicarboxylatePuas yog cov organic sib xyaw, cas {161491-24-3}}, nrog tshuaj lom neeg c11h17No4. Feem ntau nthuav tawm ua cov dawb lossis lub teeb daj daj. Nws yog yooj yim soluble hauv cov kuab tshuaj yeeb yaj kiab xws li Methanol thiab ethanol, tab sis muaj solubility qis hauv dej. Hauv kev coj ua peptide, nws tuaj yeem siv los ua qhov analogue ntawm cov amino acids kom synthesize peptides nrog cov kev sib tw tshwj xeeb. Vim nws ruaj khov 6 tus tswv cuab nplhaib koom ua ke, nws tuaj yeem ua kom tiav kev tsim ntawm Peptide daim ntawv cog lus thiab txhim kho kev ua tiav ntawm peptide synthesis. Nyob rau hauv daim teb ntawm kev kuaj kom muaj nkev thiab tsom xam, kev tsom xam tau ua tus cim lossis tshawb xyuas cov molecules lossis ions hauv cov piv txwv piv txwv. Piv txwv li, nws tuaj yeem khi rau qee cov protein lossis nucleic acids thiab muaj peev xwm txheeb xyuas los ntawm cov hau kev xws li cov tshuaj fluorescence lossis huab hwm coj.
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Tshuaj Cov Qauv |
C12h19No5 |
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Muaj pes tsawg leej |
25 |
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Molecular hnyav |
25 |
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m/z |
257 (100.0%), 258 (13.0%), 259 (1.0%) |
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Kev Ntsuam Xyuas |
C, 56.02; H, 7.44; N, 5.44; O, 31.09 |
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Morphological |
hmoov |
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Xim |
hmoov |
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Melting taw tes |
32-34 degree c |
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Kub taw tes |
35 {{0. {{{}} ± 42.0 Degree C (kwv yees) |
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Ceev |
1.175 {{0. 06 g / cm3 (kwv yees) |
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Kev Cia |
ntxig cov cua |
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Acidity Coefficient (PKA) |
11. {{0 6 ± 0.20 (kwv yees) |
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Daim ntawv thov ntawm1-} tert butyl {{}}}}}}}} dicarboxylateHauv peptide synthesis tseem ceeb heev. Raws li ib qho analogue ntawm cov amino acids, nws tuaj yeem siv los ua cov lus txhawb nqa peptides nrog cov kev sib tw tshwj xeeb.
Nruab nrab rau synthesizing peptides
Nws tuaj yeem raug siv los ua nruab nrab hauv peptide synthesis kom synthesize peptides nrog cov kev sib tw tshwj xeeb. Nyob rau hauv peptide synthesis, sab tes thiab cov pawg carboxyl ntawm cov amino acids tuaj yeem hloov kho lawv cov tshuaj thiab kev ua kom zoo. Sab saw hlau methyl thiab carbonyl pawg ntawm 1-}}}}}}}}}}} dicarboxylate tuaj yeem siv los hloov cov qauv thiab cov khoom ntawm peptides.
Txhim kho peptide synthesis efficiency
Nws tuaj yeem ua pab pawg tiv thaiv kom peptide synthesis, txhim kho cov efficiency thiab xaiv tau ntawm peptide synthesis. Kev xaiv thiab siv cov pab pawg tiv thaiv yog qhov tseem ceeb rau kev tswj hwm cov txheej txheem tshuaj tiv thaiv thiab tau txais cov tshuaj tiv thaiv zoo hauv peptide synthesis. Cov khoom tiv thaiv ntawm 1- ticarboxylate tuaj yeem tiv thaiv cov amino accts, tsis txhob muaj sab nraud tsis tsim nyog thaum lub sij hawm synthesis.
Txhawb nqa cov folding thiab ruaj khov ntawm peptides
Nws tuaj yeem ua haujlwm los hloov kho rau peptide synthesis, txhawb nqa peptide folding thiab ruaj khov. Kev xaiv thiab siv cov hloov kho hloov kho yog qhov tseem ceeb rau kev txhim kho kev ua haujlwm roj ntsha thiab kev ruaj ntseg ntawm peptide intstide synthesis. The side chain methyl of 1-tert Butyl 3-methyl-4-oxopiperidine-1 3-dicarboxylate can provide additional steric hindrance, which helps maintain the natural conformation of the peptide, improve its stability and biological activity.
Peb tuaj yeem muab cov ntsiab lus ntawm kev siv ntawm 1-}}}}}}}}}}} tert butyl {{{{}} Methyl -4- xiopiperididine -1 3- dicarboxylate) raws li nws cov qauv tshuaj thiab qeb.
- Cov Qauv Siv Tshuaj
Cov qauv ntawm 1-} trickiperidium {}}}}} piperidine nplhaib, thiab ob pawg dicarbox. Cov qauv txheem no tej zaum yuav tau txais nws nrog qee yam tshuaj lom neeg thiab cuam tshuam.
- Muaj peev xwm siv
Organic synthes intermediates
1-} Tert Butyl {}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} econ}}}}}}}}}}}} econcicteris rau synthesis ntawm ntau nyuaj orgonic teb. Cov pab pawg carboxylic thiab piperidone ntiv nplhaib hauv nws cov qauv yog cov khoom siv ua haujlwm hauv cov organic synthesis, uas tuaj yeem hloov dua siab tshiab los ntawm ntau yam tshuaj lom neeg.
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Tshuaj Kho Mob Tshuaj
Txawm hais tias tsis muaj pov thawj ncaj qha los qhia kom hais tias 1-}}}}}}}}}}}}}} eching cov khoom siv lossis theem nrab rau kev tsim tshuaj. Kws kho mob tej zaum yuav tsim cov tshuaj tshiab nrog kev kho mob cov chaw muag tshuaj los ntawm kev hloov kho thiab hloov lawv cov qauv.
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Cov ntaub ntawv kawm txuj ci
In the field of materials science, the specific structure and properties of 1-tert Butyl 3-methyl-4-oxopiperidine-1 3-dicarboxylate may enable it to play a role in the preparation of certain polymer materials, functional materials, or composite materials. Piv txwv li, nws tuaj yeem siv los ua tus neeg sawv cev hla, yas, lossis hloov kho kom txhim kho cov khoom siv lub cev lossis ua kom lawv tau txais txiaj ntsig tshiab.
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Kev Tshawb Fawb Biochemical
Due to the presence of functional groups such as carboxylic acid ester groups and piperidone rings in 1-tert Butyl 3-methyl-4-oxopiperidine-1 3-dicarboxylate, these functional groups may have certain reactivity in vivo. Yog li ntawd, 1-} tertine kev tshawb fawb raws li tus qauv ntawm biomoleculate kuj tseem siv tau rau hauv cov txheej txheem ntawm cov txheej txheem biomoleculate lossis tshawb txog cov txheej txheem ntawm cov tshuaj tiv thaiv biochemical.
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1-} tert butyl {{}}}}}}}} dicarboxylateyog qhov sib txuas nrog kev ua haujlwm tseem ceeb ntawm lub cev, yog li nws synthesis hauv chav kuaj yog qhov tseem ceeb ntawm qhov tseem ceeb.
Cov kauj ruam synthesis
(1) hnov mob tert tert betyl cawv nrog HCL los tsim tertate tlertide.
Ch3(Ch3) Ch2Oh + hc → ch3(Ch3) Ch2CL + H2O
(2) Kev tshwm sim tertinyl chloride nrog Ethyl Bromoacetate los tsim cov tert betyl {} bromo {2}} oxopiperididididation.
Ch3(Ch3) Ch2Cl + c2H5Tus yoov liab2Br → ch3(Ch3) Ch2CH (B) COOCH2Br + hbr
(3) Kev tshwm sim tert butyl 3- bromo {2} aiphe est xe x {}}} oxopiperidididididididididation.
Ch3(Ch3) Ch2CH (B) COOCH2Br + naoh → ch3(Ch3) Ch2Cooj2Cont - Nabr + h2O
(4) hnov mob tert butyl 3- ecopiperididium nrog pyridine los tsim cov tertin 3, {}} dioxopiperidine.
CH3 (CH3) CH2COCH2CONS +CONS + PY → CH3(Ch3) Ch2Cooj2Luam + Napy
(5) Kev tshwm sim tert butyl 3, 4- dioxipiperidine nrog H2O los tsim {4 4}}} dioxopiperidine chloride.
Cov txiaj ntsig zoo hauv Peptide synthesis:
Zoo tshuaj ruaj khov
Nws muaj cov tshuaj ruaj khov zoo thiab tuaj yeem tswj hwm nws cov qauv txheej txheem kev ncaj ncees thaum lub sij hawm peptide synthesis. Hauv cov txheej txheem peptide, cov saw hlau thiab cov pab pawg carboxyl ntawm cov amino acids yuav raug cuam tshuam los ntawm reagents xws li cov kua qaub thiab hauv paus, ua rau sab nraud. Txawm li cas los xij, nws muaj qhov ruaj khov zoo thiab tuaj yeem tiv thaiv cov cawv ntawm cov tshuaj reagents, ua kom cov synthesis du ntawm peptides.
Yooj yim rau kev khiav lag luam thiab ntxuav
Yooj yim ua haujlwm thiab ua kom huv hauv peptide synthesis. Kev xaiv thiab kev xaiv cov pab pawg tiv thaiv thiab cov qauv hloov kho yog qhov tseem ceeb rau kev ua haujlwm thiab cov txheej txheem purification hauv peptide synthesis. Ua ib pawg tiv thaiv thiab hloov kho, nws cov khoom ua kom nws yooj yim kom nws tau yooj yim nrog cov amino acids thiab lwmyam ntawm peptides hauv cov qauv tsim nyog.
Muab cov saw txuas ntxiv hauv qab
Vim tias muaj ntawm 1, {3- dicarborony bond kev cuam tshuam cov nyhuv ntawm peptides, txhim kho lawv cov kev ruaj ntseg, txhim kho lawv cov kev ruaj khov thiab roj ntsha. Tsis tas li ntawd, nws tseem muab txoj kev tswj tau zoo thiab ua tau zoo los cuam tshuam thiab hloov cov yam ntxwv ua haujlwm ntawm cov protein.
Yog li ntawd, cov compound no tau dav cov ntaub ntawv thov kev cia siab hauv protein engineering thiab tsim tshuaj.
- Kev cob qhia yav tom ntej
Although 1-tert Butyl 3-methyl-4-oxopiperidine-1,3-dicarboxylate has many advantages and application prospects in peptide synthesis, there are still many challenges that need to be addressed. Cov lus qhia yav tom ntej muaj xws li:
1. Txhim kho cov khoom siv hluav taws xob synthesis
Txuas ntxiv ua kom muaj kev ua kom zoo dua qub thiab cov kauj ruam los txhim kho kev ua tau zoo ntawm1-} tert butyl {{}} methyl -1 3- dicarboxylatehauv peptide synthesis. Qhov no tuaj yeem koom nrog kev tsim cov catalysts tshiab, txhim kho cov mob, lossis cov tswv yim zoo rau cov tswv yim peptide.
2. Tshawb xyuas cov ntawv thov tshiab
Applying 1-tert Butyl 3-methyl-4-oxopiperidine-1,3-dicarboxylate to other types of synthetic reactions, exploring its new applications in drug development, materials science, and other fields.
4-} Oxo-Piperidine {2}}} egehle} Txawm li cas los xij, raws li cov tshuaj tiv thaiv tshwj xeeb xws li cov tshuaj kub tsim nyog xws li cov tshuaj tiv thaiv kub, nws tuaj yeem koom nrog kev hloov pauv ntau yam thiab kev hloov kho kev hloov kho. Cov kev tawm tsam no tsis nthuav dav cov ntawv thov ntawm cov compound, tab sis kuj tseem muab tau rau synthesizing ntau txoj thiab ua haujlwm organic molecules.
Cov tshuaj ester hloov pauv yog ib qho kev tiv thaiv tseem ceeb uas tuaj yeem tshwm sim raws tshwj xeeb. Los ntawm Ester kev sib pauv, tus ester moiety nyob rau hauv cov compound tuaj yeem sib pauv nrog lwm tus ester compound los tsim cov khoom lag luam tshiab. Qhov tshuaj tiv thaiv no yog qhov tseem ceeb hauv cov organic synthesis thiab tuaj yeem siv los ua ke organic molecules nrog cov qauv tshwj xeeb thiab cov haujlwm.
Kev tso siab tau hais txog yog lwm qhov kev tawm tsam tseem ceeb uas cov lus sib txuas no tuaj yeem koom nrog. Thaum lub sij hawm cov txheej txheem taug kev, cov pab pawg carboxyl ntawm cov khoom tuaj yeem hnov mob nrog ammonia lossis amine compounds los tsim kev sib txuas lus uas kuv tau tsim. Qhov kev cog lus rau cov neeg sawv cev yog ib qho ntawm cov kev sib raug zoo ntawm biomolecules, yog li cov tshuaj tiv thaiv no muaj kev cia siab thov cov tshuaj thiab tshuaj tua kab.
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