Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm 2-chloro-4,6-dimethoxypyrimidine cas 13223-25-1 nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo 2-chloro-4,6-dimethoxypyrimidine cas 13223-25-1 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
2-Chloro-4,6-dimethoxypyrimidineyog ib qho organic compound nrog cov mis mos Molecular ntawm C6H7ClN2O2, CAS 13223-25-1, thiab molecular hnyav ntawm 174.58 g / mol. Nws yog dawb crystalline khoom. Lub melting point ntau yog feem ntau ntawm 70 thiab 74℃C. Soluble nyob rau hauv ib co organic solvents nyob rau hauv chav tsev kub, xws li ethanol, methanol, Dimethyl sulfoxide, thiab lwm yam. Relatively ruaj nyob rau hauv cov pa kev sim tej yam kev mob. Nws tuaj yeem khaws cia rau lub sijhawm ntev hauv qhuav, tsaus, thiab ntim ntim. Nws muaj ntau yam kev siv hauv ntau yam ntawm electrochemistry.
Nws ua lub luag haujlwm tseem ceeb hauv thaj chaw xws li cov khoom siv hluav taws xob, electrocatalysts, electrolytes, sensors, electroanalysis, thiab electrochemical synthesis. Los ntawm kev tsim thiab ua kom zoo dua cov ntaub ntawv thiab cov txheej txheem, kev tsim cov tshuab hluav taws xob hluav taws xob tuaj yeem txhawb nqa, txhawb kev nce qib hauv kev hloov hluav taws xob, kev saib xyuas ib puag ncig, thiab biomedical fields.
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C.F |
C6H7ClN2O2 |
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E.M |
174 |
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M.W |
175 |
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m/z |
174 (100.0%), 176 (32.0%), 175 (6.5%), 177 (2.1%) |
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E.A |
C, 41,28; H, 4.04; 20,31, 20; N, 16.05 Nws. 18.33 Nws |
2-chloro-4,6-dimethoxypyrimidine(CAS naj npawb: 13223-25-1), tseem hu ua 4,6-dimethoxy-2-chloropyrimidine, yog ib yam khoom tseem ceeb hauv thaj chaw tshuaj tua kab. Raws li cov tshuaj tua kab nruab nrab, nws ua lub luag haujlwm tseem ceeb hauv kev sib txuas ntawm cov tshuaj tua kab mob uas muaj txiaj ntsig zoo thiab tsis tshua muaj tshuaj tua kab mob.
Taw qhia
Cov tshuaj tua kab ua lub luag haujlwm tseem ceeb hauv kev ua liaj ua teb, vim tias lawv tuaj yeem tswj cov nroj tsuag, kab tsuag, thiab kab mob zoo, thiab txhim kho qoob loo thiab zoo. Txawm li cas los xij, cov tshuaj tua kab ib txwm muaj teeb meem xws li kev mob toxicity siab thiab lub sij hawm ntev residue, ua rau muaj kev hem thawj rau ib puag ncig thiab tib neeg kev noj qab haus huv. Yog li ntawd, txoj kev loj hlob ntawm kev ua tau zoo, tsis muaj tshuaj lom, thiab cov tshuaj tua kab hauv ib puag ncig tau dhau los ua ib qho ntawm cov hotspots hauv thaj chaw ntawm tshuaj tua kab chemistry.As ib qho tseem ceeb ntawm cov tshuaj tua kab nruab nrab, nws tau pom muaj peev xwm loj hauv kev tsim cov tshuaj tua kab tshiab vim nws cov qauv tshuaj lom neeg thiab cov khoom siv tshwj xeeb.
Los ntawm kev hloov kho thiab hloov kho nws cov qauv, cov khoom sib txuas nrog cov txheej txheem sib txawv ntawm kev ua.
Thiab kev tswj cov nroj tsuag muaj txiaj ntsig zoo tuaj yeem npaj tau, muab kev txhawb zog rau kev ua liaj ua teb.
Synthesis ntawm Salicylic Acid Pyrimidine Series herbicides
Salicylic acid pyrimidine series herbicides yog ib chav kawm ntawm cov tebchaw nrog kev tswj cov nroj tsuag zoo, uas ua tiav kev tswj cov nroj tsuag los ntawm kev cuam tshuam nrog kev loj hlob ntawm cov nroj tsuag.
Raws li ib qho tseem ceeb nruab nrab ntawm kev sib txuas ntawm salicylic acid pyrimidine herbicides, nws qhov tseem ceeb yog nws tus kheej - pov thawj.In the synthesis process of salicylic acid pyrimidine herbicides, compounds with herbicides are formed by specific chemical reactions with salicylic acid or its derivatives. Cov tebchaw no tsis yog tsuas yog muaj kev ua haujlwm zoo tshuaj ntsuab xwb, tab sis kuj yog ib puag ncig tus phooj ywg, nrog lub sijhawm luv luv thiab cuam tshuam tsawg kawg rau kev loj hlob qoob loo.
Kev npaj tshuaj tua kab mob xws li bisoprolol
Diclofenac yog ib qho tshuaj tua kab mob uas muaj txiaj ntsig thiab tsis tshua muaj toxicity feem ntau yog siv rau kev cog qoob loo. Nws tuaj yeem cuam tshuam kev loj hlob ntawm cov nroj tsuag thiab muaj kev cuam tshuam me me rau kev loj hlob ntawm nplej. Ua lub luag haujlwm tseem ceeb hauv cov txheej txheem synthesis ntawm bisoprolol.
Thaum synthesizing bisoprolol, nws thawj zaug reacts nrog cov cawv tshwj xeeb los tsim cov khoom nruab nrab. Tom qab ntawd, cov khoom lag luam nruab nrab tau dhau los ntawm cov tshuaj lom neeg thiab thaum kawg hloov mus rau hauv dicotyledonous ether.
Txoj kev sib xyaw no tsis yog tsuas yog yooj yim rau kev khiav lag luam, tab sis kuj muaj cov txiaj ntsig zoo thiab cov khoom ruaj khov, muab cov tshuaj zoo rau kev tswj cov nroj tsuag hauv cov nplej.
Synthesis ntawm herbicides xws li azoxystrobin
Azoxystrobin yog ib qho dav -spectrum thiab muaj txiaj ntsig zoo tshuaj tua kab mob feem ntau yog siv los tswj ntau yam dav - tawm cov nroj tsuag thiab cov nyom nyom. Nws tuaj yeem ua tiav kev tswj cov nroj tsuag los ntawm inhibiting photosynthesis ntawm cov nroj tsuag. Nws kuj ua lub luag haujlwm tseem ceeb hauv kev sib txuas ntawm azoxystrobin.Thaum ua kom cov azoxystrobin.
Nws thawj zaug reacts nrog tshwj xeeb thiol tebchaw los tsim sulfide bonds.Tom qab ntawd, los ntawm ib tug series ntawm cov tshuaj tiv thaiv, thioether daim ntawv cog lus yog hloov dua siab tshiab rau hauv ib tug compound nrog herbicidal kev ua si.
Txoj kev sib xyaw no tsis yog tsuas yog muaj cov yam ntxwv ntawm kev ua haujlwm siab thiab tsis muaj tshuaj lom, tab sis kuj tuaj yeem xaiv cov nroj tsuag sib txawv ntawm cov nroj tsuag, txhim kho cov nroj tsuag tswj cov nyhuv.
Synthesis ntawm herbicides xws li azoxystrobin
Maicao Ke yog ib qho tshuaj tua kab mob uas muaj txiaj ntsig thiab tsis muaj tshuaj lom uas yog siv los tswj cov nroj tsuag hauv thaj av. Nws tuaj yeem ua tiav kev tswj cov nroj tsuag los ntawm kev cuam tshuam nrog kev loj hlob ntawm cov nroj tsuag. Nws kuj tseem ua lub luag haujlwm tseem ceeb hauv cov txheej txheem synthesis ntawm azoxystrobin.Thaum synthesizing glyphosate, nws reacts nrog cov amine tebchaw tshwj xeeb los tsim cov tebchaw nrog cov tshuaj ntsuab. Cov tshuaj no tsis tsuas yog muaj kev tswj cov nroj tsuag zoo xwb, tab sis kuj muaj kev cuam tshuam me ntsis rau kev loj hlob ntawm cov qoob loo thiab yog ib puag ncig tus phooj ywg.Yog li ntawd, glyphosate tau siv dav hauv kev ua liaj ua teb.
Synthesis ntawm herbicides xws li pyrimidine oxime herbicide
Pyrimidine oxime herbicide yog ib qho tshiab, ua tau zoo, thiab dav -spectrum tshuaj tua kab mob tsuas yog siv los tswj cov nroj tsuag hauv teb nplej. Nws tuaj yeem ua tiav kev tswj cov nroj tsuag los ntawm inhibiting kev loj hlob ntawm cov nroj tsuag. Nws kuj ua lub luag haujlwm tseem ceeb hauv cov txheej txheem synthesis ntawm pyrimethanil.Thaum synthesizing pyrimethanil, nws thawj zaug reacts nrog oxime tebchaw los tsim cov tebchaw nrog herbicidal kev ua. Qhov kev sib xyaw no tsis yog tsuas yog muaj kev ua haujlwm zoo tshuaj ntsuab xwb, tab sis kuj muaj kev cuam tshuam me ntsis rau kev loj hlob ntawm cov nplej thiab yog ib puag ncig tus phooj ywg. Yog li ntawd, pyrimethanil tau siv dav hauv kev tswj cov nroj tsuag hauv cov nplej.
Qhov zoo ntawm cov tshuaj tua kab intermediates
Raws li qhov nruab nrab ntawm cov tshuaj tua kab, cov tshuaj tua kab hluavtaws muaj cov tshuaj tua kab mob zoo. Cov tshuaj tua kab mob no tuaj yeem cuam tshuam cov nroj tsuag kev loj hlob, txhim kho qoob loo thiab zoo. Nyob rau tib lub sijhawm, lawv muaj kev cuam tshuam me ntsis rau kev loj hlob ntawm cov qoob loo thiab tsis ua rau phytotoxicity.
Synthetic herbicides muaj cov yam ntxwv ntawm kev xaiv cov nroj tsuag. Lawv tuaj yeem xaiv cov nroj tsuag sib txawv ntawm cov nroj tsuag nrog me ntsis cuam tshuam rau cov qoob loo loj hlob.
Qhov kev xaiv tswj cov nroj tsuag no muaj txiaj ntsig zoo rau kev txhim kho kev tswj cov nroj tsuag, txo kev siv tshuaj tua kab, thiab txo cov nqi ua liaj ua teb.
Raws li cov tshuaj tua kab nruab nrab, nws txoj kev sib txuas yog qhov yooj yim thiab yooj yim rau kev khiav lag luam.
Lub caij no, cov tshuaj tua kab mob no kuj yooj yim rau kev ua thiab khaws cia, ua kom yooj yim rau kev siv hauv kev ua liaj ua teb.
Txheej txheem cej luam ntawm cov synthesis ntawm2-Chloro-4,6-dimethoxypyrimidinesiv Malononitrile, methanol thiab monocyandiamide:
Ua ntej, npaj ob cov tshuaj pib, Malononitrile (CH3C ∨ N) thiab methanol (CH3OH). Lawv feem ntau tuaj yeem yuav los ntawm cov chaw muag khoom lag luam lossis cov khoom sib txuas uas siv cov txheej txheem sib xyaw ua ke.
(1) Kev npaj cov tshuaj reactants: sib tov Malononitrile thiab methanol hauv ib qho kev faib ua feem los tsim cov tshuaj tiv thaiv.
(2) Ntxiv cov catalyst: Ntxiv qhov tsim nyog ntawm sodium cyanide (NaCN) rau cov tshuaj tiv thaiv raws li catalyst.
Cov tshuaj tiv thaiv no feem ntau yog ua los ntawm cua sov thiab nplawm. Cov tshuaj tiv thaiv kub thiab lub sijhawm tuaj yeem hloov kho raws li kev kuaj mob tshwj xeeb thiab kev tswj xyuas cov tshuaj tiv thaiv.
Cov txheej txheem synthesis no suav nrog ntau- cov tshuaj tiv thaiv kab mob. Cov hauv qab no yog ib qho piv txwv yooj yim ntawm Chemical equation, uas tsuas yog siv los piav txog cov txheej txheem tshuaj tiv thaiv. Cov tshuaj tiv thaiv tiag tiag yuav koom nrog ntau cov khoom nruab nrab thiab cov kauj ruam:
C3H2N2+CH3OH+NaCN → Cov khoom nruab nrab 1
Cov khoom nruab nrab 1+CH3OH + HCl → Cov khoom nruab nrab 2
Cov khoom nruab nrab 2+CH3OH + HCl → C6H7ClN2O2+H2O + NaCl
Thov nco ntsoov tias qhov no tsuas yog ib qho piv txwv yooj yim ntawm Chemical equation, thiab cov tshuaj tiv thaiv tiag tiag yuav koom nrog ntau tus neeg nruab nrab thiab kev ua kom zoo ntawm cov tshuaj tiv thaiv. Ua ntej ua qhov kev sim, thov nco ntsoov xa mus rau cov ntaub ntawv tshawb fawb tshiab thiab cov lus qhia txog kev sim kom paub meej ntxiv thiab raug.
2-Chloro-4,6-dimethoxypyrimidine(2-chloro-4,6-di Methoxy pawg pyrimidine) yog cov organic compound, nws cov mis mos Molecular yog C7H8ClN2O2, thiab nws cov txheeb ze molecular hnyav yog 182.60. Los ntawm cov lus piav qhia ntawm nws cov qauv molecular, peb tuaj yeem nkag siab zoo dua nws cov khoom siv tshuaj lom neeg thiab kev siv.Cov qauv molecular ntawm nws muaj ib lub nplhaib pyrimidine thiab ob pawg Methoxy (- OCH3) pawg. Ntawm lub nplhaib pyrimidine, cov khoom hloov pauv nyob ntawm carbon atoms 2 thiab 6, thaum muaj cov tshuaj chlorine atom (Cl) ntawm carbon atom 2.
Cov chlorine atom no tau txais los ntawm kev hloov cov hydrogen atom ntawm lub nplhaib pyrimidine.Ntxiv, ob pawg Methoxy pawg hauv cov khoom tau txuas nrog carbon atoms 4 thiab 6.Cov pab pawg Methoxy yog tsim los ntawm ib qho carbon atom thiab peb hydrogen atoms ntawm methyl (- CH3) thiab ib qho pa atom ntawm Methoxys pawg (O). cov qauv molecular, lub nplhaib pyrimidine muaj tsib carbon atoms thiab ib tug nitrogen atom, txhua tus uas tsim ib tug Covalent daim ntawv cog lus nrog cov nyob ib sab carbon atoms thiab nitrogen atoms.
Cov pa roj carbon atoms 2 thiab 6 ntawm lub nplhaib pyrimidine txuas nrog cov pab pawg hloov pauv los ntawm ib daim ntawv cog lus.To suav nrog, cov qauv molecular ntawm cov khoom tuaj yeem piav qhia luv luv raws li hauv qab no: carbon atoms 2 thiab 6 ntawm lub nplhaib pyrimidine yog hloov los ntawm ib qho chlorine atom thiab ob pawg Methoxy pawg. Cov qauv no ua rau nws muaj txiaj ntsig tseem ceeb hauv kev lag luam xws li tshuaj tiv thaiv electrochemical, electrocatalysis, thiab electrochemical tsom xam.
Cov lus nug nquag
Vim li cas nws thiaj suav hais tias yog ib qho zoo tshaj plaws electrophilic reagent rau tsim chiral chaw hauv asymmetric synthesis?
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Cov tshuaj chlorine atom ntawm txoj hauj lwm 2 yog ib pab pawg uas muaj zog heev, thaum ob pawg methoxy ntawm txoj haujlwm 4 thiab 6 yog cov pab pawg muaj zog electron pub dawb. Cov qauv hluav taws xob no muab nws txoj haujlwm 2-txoj haujlwm carbon muaj zog electrophilicity, tab sis tib lub sijhawm, nws yog "mos" thiab yooj yim rau kev xaiv SNAR (aromatic nucleophilic hloov pauv) cov tshuaj tiv thaiv nrog ntau yam nucleophiles, suav nrog chiral nucleophiles.
Nws ua li cas ua tus yuam sij "choj" molecule thaum tsim "pyrimidine fused heterocycles"?
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Nws tuaj yeem ua tus electrophilic reagent thiab undergo cyclic condensation nrog bifunctional nucleophiles (xws li ortho phenylenediamine) los tsim fused nplhaib systems xws li quinazolines hauv ib kauj ruam; Xwb, nws tuaj yeem cuam tshuam nrog nucleophilic reagent ua ntej, thiab cov pab pawg methoxy lossis chlorine ntxiv tuaj yeem ua rau lub voj voog txuas ntxiv kom ua tiav cov qauv thiab cov kauj ruam - los ntawm - kauj ruam kev tsim kho ntawm txoj kev heterocycles.
Puas muaj qhov sib txawv ntawm qhov reactivity ntawm nws ob pawg methoxy?
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Yuav ua li cas mus cuag xaiv deprotection los yog hloov dua siab tshiab? Feem ntau, vim yog symmetry, cov haujlwm ntawm ob pawg methoxy yog sib npaug. Txawm li cas los xij, nyob rau hauv cov xwm txheej tshwj xeeb (xws li muaj zog Lewis acid catalysis lossis kev qhia txog cov pab pawg loj steric hindrance ua ntej), xaiv demethylation lossis hloov pauv ntawm ib qho ntawm cov methoxy pawg tuaj yeem ua tiav los ntawm steric hindrance lossis hluav taws xob sib txawv, muab kev muaj peev xwm rau cov kev sib txawv tom ntej.
Vim li cas nws yog "lub hnub qub" nruab nrab rau kev tsim cov tshuaj tua kab mob zoo heev (xws li sulfonylureas) hauv tshuaj tua kab?
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Vim hais tias nws zoo kawg nkaus integrates cov tshuaj tiv thaiv qhov chaw tseem ceeb uas yuav tsum tau rau kev hloov kho tom ntej: chlorine atoms pab txhawb kev qhia txog nitrogen-muaj heterocycles; Methoxy tuaj yeem hydrolyzed rau hauv pawg hydroxyl, uas tuaj yeem muab tau los rau hauv sulfonylurea bridging bonds. Qhov no ua rau txoj hauv kev rau kev sib txuas cov tshuaj tua kab kawg los ntawm nws ua cov khoom pib luv luv, ua haujlwm tau zoo, thiab kev lag luam atomically.
Vim li cas nws thiaj hais tias muaj feem ntau tsis pom kev ruaj ntseg txaus ntshai hauv kev cia thiab kev ua haujlwm?
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Txawm hais tias ruaj khov dua li aliphatic chlorinated tebchaw, lawv cov tshuaj chlorine atoms tseem muaj qee yam reactivity. Tej zaum yuav maj mam hydrolyze nyob rau hauv qhov chaw ntub dej; Lub sij hawm ntev raug rau huab cua los yog lub teeb yuav ua rau darkening ntawm cov xim thiab txo purity. Yog li ntawd, nws yuav tsum tau muab khaws cia rau hauv qhov chaw qhuav, tsaus, kaw ntom nti, thiab yuav tsum tsis txhob tso tseg rau lub sijhawm ntev.
Cim npe nrov: 2-chloro-4,6-dimethoxypyrimidine cas 13223-25-1, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom