2-Chloronicotinic Acid CAS 2942-59-8

Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm 2-chloronicotinic acid CAS 2942-59-8 hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo 2-chloronicotinic acid cas 2942-59-8 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.

2-Chloronicotinic acidyog ib qho organic compound nrog CAS 2942-59-8 thiab tshuaj formula C6H4ClNO2. Nws yog dawb crystalline hmoov. Lub solubility hauv dej yog qhov tsawg, txog 0.9 grams ib 100 milliliters dej. Thaum kub hnyiab hauv huab cua, tshuaj lom nitrogen oxide gases raug tsim. Nws muaj zoo solubility nyob rau hauv cov organic solvents xws li ethanol, acetone, thiab dimethyl sulfoxide. Nws yog cov organic acid nrog cov kua qaub aqueous thiab pH tus nqi qis dua 7. Nws yog ib qho asymmetric molecule thiab yog li ntawd muaj chirality. Nws tuaj yeem muaj ob lub chiral isomers, uas yog sab laug thiab sab xis.

Melting point 42-45? C , Boiling point 109.7℃C , Ceev 1.25 ( 14 % aq. ), Refractive index n20 / D 1.378 , Cia txias txias , Acidity coefficient ( pKa ) -4.06 ± 0.40 ( Predicted ). Incompatible nrog muaj zog oxidizing neeg sawv cev. , Hazardous mark C, N, T, Xn , Hazard qeb code 34-43-50-20 / 21 / 22-50 / 53-23 / 24 / 25-42 / 43 , Kev nyab xeeb cov lus qhia 26-36 / 37 / 39-45-60-23-23s , Kev nyab xeeb ntawm 26-36 / 37 / 39-45-60-27-23-s No.UN 1760 8 / PG 2 , WGK Lub Tebchaws Yelemees 1 , RTECS NX8156850 , HazardClass 8, Packing Group III.

2-chloronicotinic acid(tshwj xeeb lub npe: 2-chloro-3-pyridinecarboxylic acid) yog ib qho tseem ceeb zoo tshuaj nruab nrab, uas muaj ntau yam kev siv nyob rau hauv ntau yam xws li tshuaj tua kab, tshuaj, dyes, thiab lwm yam vim nws cov cim tshuaj thiab physiological kev ua si.

Tshuaj tua kab

 

1. Tshuaj tua kab mob
Fipronil: ib qho tseem ceeb nruab nrab rau kev sib txuas ntawm sulfonylurea herbicide Fipronil. Nicotine sulfometuron yog ib qho ua tau zoo, tsis muaj tshuaj lom, thiab dav -spectrum tshuaj tua kab mob dav siv hauv cov qoob loo xws li pob kws thiab nplej, uas tuaj yeem tswj tau ntau yam nroj tsuag txhua xyoo thiab txhua xyoo.
Pifluoroacetamide: Nws kuj yog ib qho tseem ceeb nruab nrab ntawm amide herbicide Pifluoroacetamide. Pifluoroacetamide muaj intrinsic absorption conductivity thiab tuaj yeem nqus tau los ntawm cov hauv paus hniav thiab nplooj ntawm cov nroj tsuag, cuam tshuam nrog lawv cov photosynthesis thiab ua tiav kev tswj cov nroj tsuag.

 

Lwm yam tshuaj tua kab mob: Lawv kuj tuaj yeem siv los tsim lwm hom tshuaj tua tsiaj, xws li fluazinam, uas ua lub luag haujlwm tseem ceeb hauv kev ua liaj ua teb.

Synthesis ntawm fungicides
Imidacloprid: tuaj yeem siv los tsim cov tshuaj amide fungicides xws li Imidacloprid. Imidacloprid yog ib qho dav -spectrum, cov kab mob fungicide uas muaj kev tswj xyuas zoo rau ntau yam kab mob xws li grey pwm thiab rot.
Lwm cov kab mob fungicides: Nws cov derivatives kuj tuaj yeem siv los tsim lwm hom fungicides, muab kev tiv thaiv kab mob rau cov qoob loo.
Qhov zoo ntawm cov tshuaj tua kab intermediates

 

Efficiency: Cov khoom siv tshuaj tua kab hluavtaws feem ntau muaj cov yam ntxwv ntawm kev ua haujlwm siab, tsis muaj tshuaj lom, thiab dav spectrum, uas tuaj yeem ua tau raws li cov kev cai ntawm kev ua liaj ua teb niaj hnub rau kev ua haujlwm ntawm cov tshuaj tua kab.

Environmental friendliness: Nrog rau kev paub txog kev tiv thaiv ib puag ncig, cov kev xav tau rau kev ua phooj ywg ib puag ncig ntawm cov tshuaj tua kab kuj nce siab thiab siab dua. Cov khoom siv tshuaj tua kab hluavtaws feem ntau muaj qhov cuam tshuam rau ib puag ncig tsawg thiab ua tau raws li qhov yuav tsum tau muaj ntawm kev txhim kho kom ruaj khov.
Kev lag luam xav tau kev loj hlob: Nrog rau kev loj hlob ntawm kev ua liaj ua teb thoob ntiaj teb, qhov kev thov rau cov tshuaj tua kab zoo thiab ib puag ncig tus phooj ywg tseem nce ntxiv. Raws li cov tshuaj tua kab nruab nrab, nws cov kev xav tau ntawm kev lag luam tseem tab tom qhia txog kev loj hlob.

Kev kho mob teb

 

1. Tshuaj tiv thaiv AIDS
Nevirapine yog ib qho tseem ceeb nruab nrab rau kev sib txuas ntawm HIV rov qab transcriptase inhibitor Nevirapine. Nevirapine tuaj yeem ncua kev nce qib ntawm AIDS los ntawm inhibiting qhov rov qab transcriptase kev ua haujlwm ntawm tus kab mob HIV thiab tiv thaiv tus kab mob replication.
Lwm cov tshuaj tiv thaiv AIDS: nws cov derivatives kuj tuaj yeem siv los tsim lwm hom tshuaj tiv thaiv AIDS, muab ntau txoj kev kho mob rau cov neeg mob AIDS.

2. Cov tshuaj tiv thaiv kev nyuaj siab
Mirtazapine: tuaj yeem siv los tsim cov tshuaj tiv thaiv kev ntxhov siab Mirtazapine. Mirtazapine txhim kho cov tsos mob ntawm kev nyuaj siab thiab txhim kho cov neeg mob lub neej zoo los ntawm kev tswj cov qib neurotransmitter.

 

Lwm cov tshuaj tiv thaiv kev ntxhov siab: Nws cov derivatives kuj tuaj yeem siv los ua ke rau lwm hom tshuaj tiv thaiv kev ntxhov siab kom tau raws li kev kho mob ntawm cov neeg mob sib txawv.
3. Cov tshuaj tiv thaiv - mob thiab cov tshuaj analgesic
Niflufenamic acid: ib qho tseem ceeb nruab nrab rau synthesis ntawm nonsteroidal anti-inflammatory thiab analgesic tshuaj Nifluamic acid. Niflufenamic acid exerts anti-inflammatory thiab analgesic teebmeem los ntawm inhibiting prostaglandin synthesis, thiab yog dav siv nyob rau hauv kev kho mob ntawm cov kab mob xws li mob caj dab rheumatoid thiab osteoarthritis.
Pralofen: Nws kuj tuaj yeem siv los tsim cov tshuaj tiv thaiv -Pralofen. Pralofen muaj tshuaj tiv thaiv -inflammatory, antipyretic, thiab analgesic teebmeem, thiab feem ntau yog siv los kho mob nyob rau hauv ophthalmology, otolaryngology, thiab lwm yam teb.

 

Lwm cov tshuaj tiv thaiv - mob thiab tshuaj tua kab mob: Lawv cov kab mob biology kuj tuaj yeem siv los ua ke rau lwm hom tshuaj tiv thaiv - mob thiab tshuaj tua kab mob, muab cov kev kho mob zoo rau cov neeg mob.
4. Lwm yam khoom siv tshuaj
Tsiaj tshuaj tiv thaiv-cov tshuaj tiv thaiv kab mob, xws li flunixin meglumine, kuj tuaj yeem siv los ua cov tshuaj tiv thaiv tsiaj los tiv thaiv -cov tshuaj tiv thaiv kab mob, muab cov tshuaj tseem ceeb rau kev yug tsiaj.

 

Qhov zoo ntawm cov tshuaj intermediates:
Kev sib txawv: Muaj ntau yam khoom siv kho mob, suav nrog ntau yam xws li tshuaj tiv thaiv AIDS, tshuaj tiv thaiv kev ntxhov siab, tshuaj tiv thaiv - mob thiab tshuaj tua kab mob, ua tau raws li kev kho mob ntawm cov kab mob sib txawv.
Innovation: Nrog kev txhim kho txuas ntxiv ntawm cov cuab yeej siv tshuaj, qhov kev thov rau cov tshuaj tshiab yog nce ntxiv. Raws li kws tshuaj nruab nrab, nws muab cov ntaub ntawv tseem ceeb rau kev txhim kho cov tshuaj tshiab.
Kev ua lag luam muaj peev xwm: Nrog kev loj hlob ntawm cov pej xeem thoob ntiaj teb thiab kev siv zog ntawm kev laus, qhov kev thov rau cov khoom siv tshuaj tseem nce ntxiv. Raws li cov kws kho mob nruab nrab, nws txoj kev lag luam muaj peev xwm loj heev.

Dye field

 

Dye intermediates: kuj tseem siv tau los ua cov xim intermediates rau kev sib txuas cov dyes tshwj xeeb. Cov dyes muaj ntau yam kev siv hauv textile, luam ntawv thiab dyeing industries, muab nplua nuj xim xaiv rau cov khoom.
Qhov zoo ntawm dye intermediates:
Xim nplua nuj: Cov khoom siv hluavtaws muaj cov xim ci thiab muaj ntau haiv neeg, uas tuaj yeem ua tau raws li cov xim xav tau ntawm kev lag luam sib txawv.
Kev ruaj ntseg: Cov dyes feem ntau muaj kev ruaj ntseg zoo thiab tuaj yeem tuav cov xim zoo nkauj hauv qhov chaw sib txawv, txuas ntxiv cov khoom siv lub neej.

Lwm yam teb

 

Cov hlau ligands: lawv cov derivatives xws li 2,2 '- diselenino nicotinic acid tuaj yeem siv los ua hlau ligands thiab muaj cov ntawv thov tseem ceeb hauv kev ua haujlwm ntawm cov hlau organic chemistry thiab kev sib koom ua ke chemistry.
Kev tshawb fawb thiab kev qhia: 2-chloronicotinic acid, uas yog ib qho tseem ceeb ntawm cov tshuaj nruab nrab, kuj tuaj yeem siv rau hauv kev tshawb fawb thiab kev qhia, muab cov ntaub ntawv tseem ceeb rau kev tshawb fawb tshuaj.

Peb yog cov chaw tsim khoom ntawm cov khoom.

Lus Cim: BLOOM TECH (Txij li xyoo 2008), ACHIEVE CHEM-TECH yog peb lub koom haum ntawm peb.

Nws tuaj yeem raug tsim los ntawm 3-cyanopyridine (2) los ntawm oxidation, chlorination, thiab hydrolysis tshua.

C₆H₄N₂ (2)+H₂O₂+ NaOH + CuCl₂+5HCl → C₆H₄ClNO₂+CuCl+2H₂O + NH₄Cl + Na

Ib tug sib tov ntawm2-Chloronicotinic acidthiab 2-chloro-5-methylpyridine tuaj yeem npaj los ntawm cov kauj ruam hauv qab no:

1. React 3-methylpyridine nrog hydrogen peroxide los tsim n-oxo-3-methylpyridine. Cov tshuaj tiv thaiv no yog cov tshuaj tiv thaiv oxidation, uas yog hydrogen peroxide ua oxidant rau oxidize 3-methylpyridine rau n-oxo-3-methylpyridine. Cov kauj ruam no tuaj yeem siv cov tshuaj tiv thaiv sib txawv thiab cov oxidants kom ua tiav cov txiaj ntsig zoo tshaj plaws thiab purity.

C₆H₇N+H₂O₂ → C₆H₇TSIS MUAJ

2. Cyclically chlorinate n-oxo-3-methylpyridine nrog phosphorus oxychloride kom tau txais kev sib xyaw ntawm 2-chloro-5-methylpyridine thiab 2-chloro-3-methylpyridine. Cov tshuaj tiv thaiv no yog cov tshuaj tiv thaiv chlorination, uas phosphorus oxychloride ua cov tshuaj chlorinating, hloov cov pawg hydroxyl hauv n-oxo-3-methylpyridine nrog cov tshuaj chlorine atom los tsim cov sib xyaw ntawm 2-chloro-5-methylpyridine thiab 2-chloro-3-methylpyridine. Cov kauj ruam no yuav tsum tau tswj cov tshuaj tiv thaiv kab mob, xws li kub, tshuaj tiv thaiv lub sij hawm, thiab concentration, kom ua tiav qhov zoo tshaj plaws yield thiab purity.

C₆H₇TSIS + PCl₃ → C₆H₆ClN + C₆H₆ClN

3. Nyob rau hauv lub xub ntiag ntawm acid binding tus neeg saib xyuas diisopropylamine, ib tug sib tov ntawm 2-chloro-5-methylpyridine thiab 2-chloro-3-methylpyridine yog siv los ua ib tug chlorinating tus neeg sawv cev rau crystallization thiab distillation. Lub hom phiaj ntawm cov kauj ruam no yog cais 2-chloro-5-methylpyridine thiab 2-chloro-3-methylpyridine los ntawm crystallization thiab distillation. Cov xwm txheej rau crystallization thiab distillation tuaj yeem hloov kho raws li cov xwm txheej tshwj xeeb los txhim kho cov txiaj ntsig thiab purity.

4. Hloov 2-chloro-3-methylpyridine rau 2-chloro-3-trichloromethylpyridine los ntawm sab saw chlorination. Cov tshuaj tiv thaiv no yog cov tshuaj tiv thaiv kab mob chlorination sab, uas cov roj chlorine ua cov tshuaj chlorinating, hloov cov saw ntawm 2-chloro-3-methylpyridine nrog chlorine atom los tsim 2-chloro-3-trichloromethylpyridine. Cov kauj ruam no yuav tsum tau tswj cov tshuaj tiv thaiv xws li kub, siab, thiab concentration kom ua tiav cov txiaj ntsig zoo tshaj plaws thiab purity.

C₆H₆ClN + Cl₂ → C₆H₅Cl₃N

5. Hydrolyze 2-chloro-3-trichloromethylpyridine kom tau 2-chloro-3-pyridinecarbonyl chloride los yog 2-chloro-3-pyridinecarboxylic acid. Cov tshuaj tiv thaiv no yog cov tshuaj tiv thaiv hydrolysis, uas cov dej ua cov tshuaj tiv thaiv reagent, hloov peb chlorine atoms hauv 2-chloro-3-trichloromethylpyridine nrog hydroxyl pawg los tsim 2-chloro-3-pyridinecarbonyl chloride lossis 2-chloro-3-pyridinecarboxylic acid. Cov kauj ruam no yuav tsum tau tswj cov tshuaj tiv thaiv xws li kub, pH, thiab concentration kom ua tiav cov txiaj ntsig zoo tshaj plaws thiab purity.

C₆H₅Cl₃N+H₂O → C₆H₄ClNOCl/C₆H₄ClNO₂

Cim npe nrov: 2-chloronicotinic acid CAS 2942-59-8, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom