Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam thiab cov chaw muag khoom ntawm 2-dimethylropyl chloride CAS 4584-49-0 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale loj zoo 2-dimethylropyl chloride hydrochloride CAS ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
2-dimethylascoisopropyl chloride hydrochloride, tseem hu ua 2 {-} chloro {2} n, ch3) ch2nc (ch3) ch2584-49-0. Nws yog cov hmoov nplej dawb uas yog rhiab rau lub teeb thiab huab cua. Nws yog soluble hauv cov kuab tshuaj organic xws li dej, methanol, ethanol, acetone, chloroform, thiab daim ntaub pua chaw dichroomethane. Raws li cov ntsev ntawm hydrogen chloride, nws muaj cov khoom acidic. Nyob rau hauv cov cua kub, qhov compound ua yeeb yam zoo thermal stability. Raws li ib qho tseem ceeb hauv cov organic nruab nrab, nws muaj cov ntaub ntawv dav dav hauv cov tshuaj, tshuaj tua kab, cov ntaub ntawv txuj ci, kev lag luam, thiab kev tshawb fawb ib puag ncig. Nrog kev txhim kho kev kawm txuas ntxiv thiab thev naus laus zis thiab kev tshawb nrhiav daim ntawv thov daim ntawv thov, nws cov kev siv yuav txuas ntxiv mus nthuav dav thiab enrich.
|
Tshuaj Cov Qauv |
C5h13Cl2n |
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Muaj pes tsawg leej |
157 |
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Molecular hnyav |
158 |
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m/z |
157 (100.0%), 159 (63.9%), 161 (10.2%), 158 (5.4%), 160 (3.5%) |
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Kev Ntsuam Xyuas |
C, 37.99; H, 8.29; Cl, 44.85; N, 8.86 |
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Morphological |
hmoov |
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Xim |
Dawb rau lub teeb cream |
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Ceev |
Khw hauv qab + 30℃c |
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Kev Cia |
Khw hauv qab + 30℃c |
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Solubility H2o |
2000g / L |
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|
|
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2 {- dimethylamine isopropyl chloride hydrochloride (DMAP CL) yog ib qho kev txwv qaib ammonium ntsev reagent nrog ntau yam kev siv. Piv txwv li, nws tuaj yeem siv ua alkylation thiab nucleophilic reaicents rau cov tshuaj ammonium, ntxiv rau qhov uas tsis sib xws rau qee yam tshuaj. Nws tuaj yeem tau txais los ntawm cov tshuaj tiv thaiv ntawm n, n-deegylproporanediamine thiab Ethyl Hydrochlorite. Cov tshuaj tiv thaiv no yuav tsum tau ua raws li cov nroj tsuag catalyy los ntawm trichhloride. Cov kauj ruam tshwj xeeb yog raws li hauv qab no:
Tshuaj Muaj Tshuaj:
C5H14N2{{0 {}} hcl + sbcl3 → C5H13Kwj Cl2N + sbclcl5
C6H16NCLIH HLL =} C6h16ncl2+H2O
Nco tseg: Sbcl5Nyob rau hauv qhov sib npaug saum toj saud yog ib qho los ntawm brepododuct uas tuaj yeem tso tseg thaum sib cais cov theem organic.
Khoom siv:
N. N {{{- dimethylpropanediamediamediamediamine (DMAE, Kev Ntsuam Xyuas Cov Ntshiab)
Albiation Trichhloride (Sbcl3, Kev Ntsuas Cov Pauv)
Txuj Ci Hydrogen Chlorate (HCRETT, Kev Ntsuam Xyuas Cov Phaj)
Anhydrous ether (analytical ntshiab)
Acetone (analytical ntshiab)
Sodium hydroxide (naoh, analytical ntshiab)
Dej (dej nyab lossis dej distilled)
Npaj cov reagents no cais rau cov kev tawm tsam tom ntej.
Kauj ruam:
1.
Ntxiv 15 ml ntawm anhydrod ether, 6 mL ntawm n, n - dimethylpropanediamedia rau ib lub raj mis qhuav.
2.
Do kom txog thaum muaj trichyloride yog tag nrho cov sib tov, ua kom sib xyaw.
3.
Maj mam ntxiv 10 ml ntawm ethyl chanorate rau cov tshuaj tiv thaiv sib tov, thaum ntxiv cov hlau nplaum me me, thiab txuas ntxiv nplawm rau 30 feeb. Thaum lub sij hawm cov txheej txheem cov tshuaj tiv thaiv, cov khib nyiab dawb yuav precipitate tawm.
4.
Hloov cov tshuaj tiv thaiv sib xyaw rau ib qho qhuav 500 ml cais funnel thiab cais cov kuab cov kuab tshuaj organic rau hauv qab txheej.
5.
Ntxuav ob zaug nrog sodium hydroxide tov, thiab neutralize txhua zaus nrog 50 ml ntawm cov kua aqueous.
6.
Tshem tawm cov kuab tshuaj los ntawm theem organic kom tau txais cov khoom lag luam dawb ntawm 2-dimethylamine isopropyl chloride hydrochloride.
7.
Lim cov khoom poob ntawm cov ntawv lim thiab ntxuav nws nrog acetone.
8.
Lub dmap - CL cov khoom tau los ntawm kev ziab tau los ntawm kev siv lub tshuab nqus tsev kom qhuav.
Cov lus hais: Bloom Tech (Txij xyoo 2008), ua tiav chem - tech yog cov neeg pabcuam ntawm peb.
2-dimethylascoisopropyl chloride hydrochlorideyog ib qho nruab nrab ntawm cov tshuaj xws li Yantongjing, imipramine, deepene cawv rau hauv lub siab, thiab lwm yam. 1-dimethylaminoprofr-3-Cawv Los ntawm WHERBOK rau 14 tshuaj lom neeg rau 9-10H kom tau cov khoom tiav ntawm 1-dimethylamino-3-chloropropane hydrochloride.
2-dimethylropyl chloride yog cov organic compound nrog ntau yam siv. Ntxiv rau nws cov ntawv thov nyob rau hauv cov qauv tshuaj, tshuaj tua kab, cov ntaub ntawv kev tshawb fawb, thiab kev lag luam, thiab kev lag luam tseem ceeb hauv kev tshawb fawb ib puag ncig.
1. Wastewater extractant
Nws muaj cov pab pawg hydrothobic, uas tuaj yeem siv ua ib qho extractant rau kev kho kom dej khib nyiab. Tom qab complexing los yog adsorbing nrog organic paug, organic paug yuav ua tau zoo sib cais los ntawm cov dej qias neeg tuaj yeem ua tiav lub hom phiaj ntawm kev ua kom huv lub hom phiaj. Txoj kev kho mob no yog tsim tshwj xeeb rau kev kho kom muaj wastewater muaj cov hlau hnyav thiab cov organic paug.
2. Cov dej ntws tawm
Nws tuaj yeem raug siv los ua cov flocculant rau kev kho kom dej khov. Los ntawm kev sib xyaw colloidal precoipitates nyob rau hauv dej lwg, tshem tawm cov khib nyiab, cov hlau hnyav, thiab cov organic paug tsis tuaj yeem tshem tawm. Piv nrog rau lwm cov flocculants, nws tau zoo dua Frocculation Effect thiab kev mob tshwm sim qis dua, ua rau nws muaj kuab tshuaj kho kom zoo tshaj plaws.
3. Av remediation
Nws tuaj yeem siv rau kev kho av. Los ntawm cov nyom lossis adsorbing hnyav hlau ions hauv cov av, yog li kev txo qhov kev cuam tshuam ntawm cov rog hnyav ntawm cov av ecosystem. Txoj kev no yog tshwj xeeb rau kev kho av tsis huv nrog cov hlau hnyav.
4. Cov av nkos av
Nws tuaj yeem siv tau rau txoj kev ua kom av. Los ntawm kev sib sau cov zaj duab xis hydrophobic nyob rau saum npoo av thiab av muaj kuab paug los tiv thaiv kom tsis txhob muaj kuab paug los ntawm cov av sab nraum cov av. Hom no yog tshwj xeeb rau kev kho kom zoo rau cov av tsis huv.
Zuag qhia tag nrho, nws muaj cov ntawv thov dav hauv thaj teb ntawm kev tshawb fawb ib puag ncig. Nrog kev txhim kho kev tiv thaiv ib puag ncig thiab kev txuas ntxiv mus rau ib puag ncig kev tswj hwm thev naus laus zis, nws daim ntawv thov kev cia siab yuav yog dav dav. Yav tom ntej, nws muaj peev xwm ntxiv nthuav tawm nws daim ntawv thov hauv kev tshawb fawb ib puag ncig los ntawm kev tswj hwm ib puag ncig ntawm kev ua haujlwm thiab ua kom zoo dua nws daim ntawv thov.
Nyob rau hauv lub dav dav ntawm ib puag ncig cov pa paug dav hlau tswj, kev ua si hauv av yog ib qho teeb meem tshwj xeeb thiab nyuaj. Nrog rau kev nrawm nrawm ntawm kev lag luam thiab hauv nroog, cov av muaj kuab paug hauv av tau dhau los ua kev hem thawj rau cov tsiaj txhu thiab tib neeg kev noj qab haus huv. Yog li ntawd, tshawb thiab txhim kho cov av ntawm cov av hauv av hauv av loj tshwj xeeb yog ib qho tseem ceeb. Ntawm lawv, 2 {- dimethyloride hydrochloride) tau qhia qee yam peev xwm thiab thov kev cia siab hauv av tshwj xeeb.
Daim Ntawv Thov Kev Sau Npe ntawm DMAIpc Hydrochloride Hauv Cov Av Dej
Daim ntawv thov ntawm DMAIPC Hydroporide hauv cov av tsis muaj tshuaj lom neeg thiab cov tshuaj tiv thaiv nrog cov kuab paug. Tshwj xeeb, nws tuaj yeem txhawb kev kho mob hauv av paug los ntawm cov txheej txheem hauv qab no:
Redox cov tshuaj tiv thaiv:
DMAIPC Hydrochloride lossis nws cov khoom siv hydrolysis thiab muaj peev xwm koom nrog cov kuab paug liab, hloov lawv cov tshuaj lom lossis tsis muaj kev puas tsuaj. Cov txheej txheem no yog tshwj xeeb rau kev kho cov dej hauv av uas muaj cov kua ntses hydrocarbons thiab chlorinated ntxhiab tsw qab hydrocarbons organic pollutants.
Adsorption thiab complexation:
DMAIPC hydrochloride lossis nws cov derivativatide lossis nws cov tshuaj zoo adsorption thiab adsorb hnyav hlau, thiab muaj cov orgidater hnyav thiab diffenus hauv av. Ib qho ntxiv, DMAIPC Hydrochloride kuj tseem yuav khi nrog qee cov hlau ions los ntawm kev sib tw ua kom ruaj khov, ntxiv txo nws cov tshuaj lom thiab tsis muaj txiaj ntsig.
Txhawb bioodegradation:
Txawm hais tias DMAIPC Hydroploride nws tus kheej tsis yog siv ncaj qha rau kev txhim kho microbial ntawm cov av muaj kuab lom thiab muab cov khoom siv hluav taws xob. Cov tshuab no yuav tsum tau ua ke nrog cov cuab yeej siv tshuab Bioremediation kom ua tiav cov txiaj ntsig zoo dua.
Cov piv txwv thov thiab cov zeem muag
Tam sim no, kuj muaj ob peb daim ntawv thov ncaj qha ntawm DMAIPC Hydroporide hauv cov teb av tau muaj feem ntau yog tas li. Piv txwv li, cov kws tshawb nrhiav tuaj yeem siv DMACHLOR Hydrochloride ua cov txheej txheem tshuaj lom neeg (xws li cov kev kho kom haum rau kev ua kom zoo dua qub thiab kev ua haujlwm hauv av. Nyob rau yav tom ntej, nrog hauv- qhov tob txhim kho ntawm cov kuab paug ntawm ib puag ncig kev cai thiab kev ua haujlwm tsim tawm tshiab, kev thov kev pab cuam ntawm2-dimethylascoisopropyl chloride hydrochlorideHauv av hauv av kev kho yuav yog qhov dav. Nyob rau tib lub sijhawm, cov xim yuav tsum tau them nyiaj rau nws cov teeb meem kev nyab xeeb thiab kev nyab xeeb kom ntseeg tau tias nws tsis muaj kev noj qab haus huv thiab tib neeg kev noj qab haus huv thaum siv.
Kev Kuaj Xyuas Kev Kuaj: Kev Ua Tau Zoo Ua Kua Chromatography (HPLC)
Lub ntsiab lus
Lub hom phiaj sib txuas thiab kev tsis sib thooj tau sib cais siv C18 rov qab -}} theem chromatography sab. Lub purity yog quantatively tau txheeb xyuas los ntawm ultraviolet ntes (210 nm). Txoj kev no tau ua tiav los ntawm kev siv qhov sib txawv hauv kev faib cov coefficient ntawm cov compound ntawm chaw nyob ruaj ruaj thiab cov mobile theem.
Kev Siv Kauj Ruam
Kev Npaj Qauv: hnyav kwv yees li 10 mg ntawm cov qauv, yaj nws hauv methanol thiab ua kom lub ntim mus txog 10 ml. Lim thiab npaj mus nrog qhov ntsuas.
Chromatographic mob:
Txawb theem: acetonitrile - dej (muaj 0.1% trifluoroacetic acid), gradient elove nce los ntawm 20% mus rau 80%).
Flow Rate: 1.0 ml / min.
Sab kub: 30 degree.
Kev Ntsuam Xyuas Quantalitative: Lub purity tau suav siv txoj kev coj ua ib txwm muaj. Qhov yuav tsum tau muaj ntau dua los yog sib npaug rau 99% (impurity tsawg dua los yog sib luag rau 0.5%, tag nrho cov impurity tsawg dua los yog sib npaug rau 1%).
Qhov Zoo
High rhiab (nrog rau kev kuaj pom kev txwv ntawm 0.01%), muaj peev xwm ntawm ib txhij selterating ntau impurities.
Haum rau kev tswj kom zoo ntawm qhov siab - purity raw cov ntaub ntawv (xws li APIS).
Cov Txheej Txheem Qhia Ntawv: Nuclear Sib Nqus Revering Remonce Hydrogen Spectroscopy (1h- NMR)
Lub ntsiab lus
Los ntawm kev tshuaj xyuas cov tshuaj hloov pauv, txuas ntxiv thaj chaw ntawm hydrogen atoms nyob rau hauv cov compound, cov qauv molecular thiab cov haujlwm ntawm cov pab pawg ua haujlwm tau pom zoo.
Kev Siv Kauj Ruam
Kev Npaj Qauv: Hnov li 5 mg ntawm cov qauv thiab yaj nws nyob rau hauv 0.5 ml ntawm kev ua txhaum cai chloroform (cdcl3) lossis deuterated dej (D2O).
Kuaj mob:
Ntsuas: 400 MHz nuclear sib nqus resonance spectrometer.
SCANNING SIJHAWM: 16 zaug.
Kub: 25 degree.
Kev txhais lus saib xyuas:
Paub meej tias lub methyl proton cov cim ntawm lub dimethylamino pab pawg ({0}} n (ch3) 2 (}} ppm).
Tshawb xyuas cov methylene thiab methyl proton cov cim ntawm isopropyl pab pawg ({0}} {ppm thiab} {4 4}} ppm).
Sib piv nrog cov qauv saib pom spectrum lossis cov ntaub ntawv ntaub ntawv kom ntseeg tau cov qauv txheej txheem.
Qhov Zoo
Tsis - Kev sim puas tuaj yeem muab cov molecular {{}}} Cov ntaub ntawv theem qauv qauv.
Nws yog siv rau cov qauv txheej txheem ntawm cov hluavtaws nruab nrab thiab cov khoom lag luam kawg.
Impurity tswj: roj chromatographyrographyau - huab tais loj spectrometry (gc {{1 ms)
Lub ntsiab lus
Kev sib cais ntawm kev sib cais muaj peev xwm ntawm cov roj chromatography nrog kev ntsuas qhov zoo ntawm cov roj hluav taws xob tsis txaus ntseeg (xws li {{} cov khoom lag luam) yog nqa tawm.
Kev Siv Kauj Ruam
Qauv Npaj: hnyav kwv yees li 20 mg ntawm cov qauv, yaj nws hauv dichhloromshane thiab ua kom lub ntim mus txog 10 ml. Lim thiab npaj mus nrog kev tsom xam.
Chromatographic mob:
Kab hom: DB-5ms capillary kem (30 m × 0.25 μm).
Qhov kev pab kub: Pib kub 50 degree, tuav tau 2 feeb, tom qab ntawd nce ntawm 10℃/ min txog rau 5 feeb.
Cov cab kuj roj: Helium (1.0 ml / min).
Pawg Spectrometry:
Ionization hom: hluav taws xob cuam tshuam los (EI, 70 EV).
Scan Litt: M / Z 40-500.
Kev Ntsuam Xyuas Zoo: Paub meej tus qauv ntawm impurities los ntawm txuam nrog nist mass spectrometry tsev qiv ntawv.
Kev Ntsuam Xyuas Quantitative: suav cov ncauj lus uas tsis tawg siv cov txheej txheem sab hauv (xws li rhuav tshem dhuav).
Qhov Zoo
Kev siab siab (PPB theem), muaj peev xwm ntes tau trace impurities.
Haum rau kev tswj hwm ntawm cov khoom siv volatile (vocs).
Kev Ntsuam Xyuas Kev Ruaj Ruaj: Thermogravetric tsom (TGA) thiab kev ntsuas calorimetry (DSC)
Thermogravetric tsom (TGA)
Lub hauv paus ntsiab lus: ntsuas qhov loj hloov ntawm cov qauv thaum lub sijhawm ua cua sov los ntsuas qhov hluav taws xob thermal.
Cov kauj ruam siv:
Nqus kwv yees li 5 mg ntawm cov qauv thiab muab tso rau hauv ib lub alumina crucible.
Qhov Cua Kub: 10℃/ min, Kub ntau: 30-700 degree.
Cua: nitrogen (50 ml / min).
Kev Ntsuam Xyuas:
Paub meej tias qhov kev txiav txim siab kub (piv txwv li, ntau dua lossis sib luag rau 200℃qhia tau zoo thermal stability).
Laij cov ntsiab lus residue (piv txwv li, tsawg dua los yog sib luag rau 0.5% qhia tsis muaj kev txiav txim siab tseem ceeb).
Kev ntsuas cov calorimetry (DSC)
Lub hauv paus ntsiab lus: ntsuas cov cua sov sib txawv ntawm cov qauv thiab cov khoom siv los txiav txim siab melting point thiab theem hloov pauv kub.
Cov kauj ruam siv:
Hnyav kwv yees li 2 mg ntawm cov qauv thiab muab tso rau hauv txhuas crucible.
Tus Ntaus Cua Sov: 5 Qib / Min, Kub Ntau Yam: 30-250 degree.
Cua: nitrogen (50 ml / min).
Kev Ntsuam Xyuas:
Paub meej tias lub poelting point (piv txwv li, 187-190 degree, zoo ib yam nrog cov ntawv muaj nuj nqis).
Ntes polymorphs lossis theem kev hloov pauv kev hloov pauv (piv txwv li, tsis muaj kev nkag siab ntxiv / exototmic peaks qhia cov ntawv siv lead ua ruaj khov).
Qhov Zoo
Muab cov ntaub ntawv thermodynamic los qhia kev cia cov xwm txheej cia (piv txwv li, pom zoo tsawg dua lossis sib npaug rau 30℃rau qhuav cia).
Haum rau kev kawm kev nyab xeeb ntawm cov ntaub ntawv raw thiab npaj.
Kev ntsuas kev ntsuas thiab kev lag luam kev lag luam
Txheej Txheem Xaiv Kev Xaiv
Kev Kuaj Xyuas Kev Kuaj: HPLC yog hom qauv uas nyiam, ntsib cov kws ua tshuaj ua noj ua ke (xws li USP, EP).
Tus qauv cim: 1h-} Nmr yog tus qauv kub, haum rau kev siv tau ntawm cov txheej txheem hluavtaws.
Impurity tswj: GC {- ms yog haum rau cov tsis txaus ntseeg, thiab hplc {1} {{volatile impurities.
Kev Ntsuam Xyuas Kev Ruaj Ruaj: TGA thiab DSC yog siv ua kev sib xyaw ua ke kom thiaj li ntsuas kev nkag siab ruaj khov.
Kev Lag Luam Daim Ntawv Thov Kev Ua Haujlwm
Kws Kev Lag Luam: Siv rau kev tswj hwm cov khoom nruab nrab hauv cov hluavtaws ntawm cov tshuaj antihistamines (xws li promethazine), loog hauv zos (xws li procaine).
Tshuaj tua kab kev kev lag luam: raws li ib qho alkylation reagent rau synthester rau cov tshuaj tua kab mob (xws li d butyl ester), nruj tswj ntawm impurities yog qhov tsim nyog kom tsis txhob phytotoxicity.
Cov ntaub ntawv tshawb fawb: siv rau cov synthesis ntawm polyurethane catalysts, ntsuas kev ntsuas hluav taws xob thermal kom ntseeg tau kev nyab xeeb.
Yav Tom Ntej
Siab - daws teeb meem loj tshaj (HRMS): Xws li cov qauv uas tsis raug ntsej muag thiab cov isotope faib).
Supercritical kua chromatography (SFC): Hloov cov khoom siv HPLC, ua tiav ntsuab sib cais (xws li txo qhov kev siv cov organic cov kuab tshuaj).
Cov txheej txheem tshawb hauv online: ua ke nrog Pat (txheej txheem tshuaj xyuas tshuab), ua tiav tiag {} lub sij hawm tswj tau.
Cim npe nrov: 2-dimethylropyl chloride hydrochloride CAS 4584-49-0, tus lwm tus neeg, chaw tsim khoom, chaw tsim khoom, yuav khoom, rau muag