Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov khoom lag luam ntawm 4-bromo-1-indanone CASE 15115-60-3 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale ntau qhov zoo 4-bromo-1-indanone CASone 15115-60-3 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
4-bromo-1-indanoneyog cov tshuaj sib txuas nrog cov qauv sib txawv thiab cov khoom sib txawv. Cov molecule nta ib qho kev sib tw indanone, uas yog lub nplhaib benzene, uas yog Ketone Group (c}} o) Qhov sib ntxiv ntawm lub bromine atom ntawm 4-txoj hauj lwm ntawm Benzene Ring muab rau nws, paub qhov txawv ntawm lwm cov Indanone derivatives.
Qhov no compound nthuav tawm ntau yam ntxwv tsis muaj yam ntxwv. Nws lub xeev lub cev thiab melting taw tes tuaj yeem sib txawv nyob ntawm daim ntawv huv thiab crystalline, tab sis nws yog feem ntau yog cov khoom ntawm chav sov. Lub bromine hloov tau txhim kho kom tau nws cov kev cuam tshuam, ua rau nws muaj txiaj ntsig zoo hauv cov xwm txheej organic. Vim nws cov qauv kev ruaj khov thiab cov qauv hloov pauv tshwj xeeb, nws feem ntau yog cov khoom lag luam uas tau pib ua ke nrog cov xim hlau uas txuas nrog ib lub cyclopentanone scaffold.
Ntxiv mus, nws cov hluavtaws cov versatility tso cai rau kev qhia ntawm ntau txoj haujlwm ntawm cov molecule, pab pawg ntawm cov derivatives ntau. Cov ntawv thov ncua los ntawm kev lag luam kws tshuaj, uas nws yuav pab txhawb rau cov cuab yeej ntawm biological, uas nws cov kev tshawb fawb, uas nws cov kev tshawb fawb, uas nws cov kev tshawb fawb tau siv hauv kev txhim kho cov polymers tshiab lossis cov ntaub ntawv qib siab. Zuag qhia tag nrho, nws sawv cev rau cov chaw muaj txiaj ntsig zoo nrog cov peev xwm tseem ceeb hauv ob qho kev tshawb fawb thiab kev lag luam.
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Tshuaj Cov Qauv |
C9H7BRO |
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Muaj pes tsawg leej |
209.97 |
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Molecular hnyav |
211.06 |
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m/z |
209.97 (100.0%), 211.97 (97.3%), 210.97 (9.7%), 212.97 (9.5%) |
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Kev Ntsuam Xyuas |
C, 51.22; H, 3.34; Br, 37.86; O, 7.58 |
Organic Intermediate
Synthesis ntawm cov molecules complexules
4-bromo-1-indanoneUa hauj lwm ua qhov tseem ceeb hauv nruab nrab hauv cov hluavtaws ntawm ntau yam ua ke orgules. Nws cov qauv tshuaj tshwj xeeb, muaj lub nplhaib tsis pom tseeb, pab pawg hauv paus, thiab lub bromine atom hloov ntawm C-4 txoj hauj lwm, tso cai rau cov lus qhia txog ntau yam kev ua haujlwm tshwj xeeb los ntawm kev siv tshuaj lom neeg.
Kev daws zaum kawg
INDEN HLAU
Lub nplhaib tsis pom lub nplhaib muab lub moj khaum ruaj khov uas tuaj yeem yauv hloov ntau yam kev hloov pauv. Qhov kev pab cuam uas muaj ntxhiab hauv cov khoom siv ruaj khov thiab hloov chaw, yog li pab txhawb kev ua kom du.
Ketone Group
Ketone pab pawg (c =}} o) yog koom nrog ntau cov tshuaj lom neeg, xws li kev txo qis, ntxiv, thiab hws. Nws ua haujlwm ua tus kov rau kev qhia cov kev ua haujlwm tshiab lossis kev hloov kho uas twb muaj lawm.
Bromine hloov tau
Lub bromine atom hloov nyob rau ntawm c- 4 txoj hauj lwm qhia txog kev ua haujlwm halogen ua haujlwm lossis siv rau hauv kev sib txuas lus hla. Bromine cov kev cuam tshuam rau cov lus qhia ntawm cov neeg hloov ntau yam neeg hloov chaw, yog li nthuav dav cov hluavtilatility.
Kws Tshuaj Kho Mob
Cov compound no muaj cov ntawv thov yuav hauv kev lag luam tshuaj. Raws li Indanone deranone deranone derivative, nws yuav muaj kev ua haujlwm lom neeg muaj kev sib xyaw ua ke sib txuas, xws li anti-}} mob cancer lossis neuroprotive cov yam ntxwv. Txawm li cas los xij, cov ntaub ntawv tshwj xeeb cov ntaub ntawv xav tau kev tshawb fawb ntxiv thiab kev txhim kho.
Anti -} Cancer Khoom
- Ntau cov neeg hauv Indanone tau qhia tau cog lus nyob rau hauv inhibiting txoj kev loj hlob thiab proliferation ntawm cov kabmob kheesxaws. Cov txheej txheem tshwj xeeb ntawm kev nqis tes ua yuav cuam tshuam cov phiajcim ntawm cov phiajcim kev sib tw, lossis cuam tshuam cov txheej txheem celltosis (programmed cell tuag).
- Lub Bromine hloov chaw thiab pab pawg Ketone tuaj yeem cuam tshuam nrog roj ntsha macromolecules, xws li cov protein lossis DNA, ua rau} Cancer Cov teebmeem.
Neuroprotrive Cov Khoom Siv
- Qee qhov chaw sib txuas lus hauv Indanone tau ua rau muaj kev ntxhov siab neuroprotrotective, inshibing neuroinflaty cov txheej txheem, lossis modulating neurotransmitter tshuab.
- Lub nplhaib tsis pom lub nplhaib yuav tso cai rau nws hla cov ntshav -}}} lub hlwb lub hlwb, ua rau nws tus neeg sib tw rau cov kev lom zem neurological.
Kev Tshawb Fawb Ntxiv thiab Kev Loj Hlob
Kev Kuaj Mob
- Ua hauv Vitro thiab hauv Vivo kev tshawb fawb los ntsuas qhov sib txuas ua haujlwm tawm tsam cov hom phiaj roj ntsha thiab cov kab mob kab mob.
- Kev txiav txim siab qhov sib xyaw ua ke muaj cov tshuaj lom profile thiab cov khoom siv tshuaj ntsuam xyuas kom ntsuas nws txoj kev ua haujlwm rau kev txhim kho ntxiv.
Qauv - kev sib raug zoo (sar)
- Tshawb xyuas seb kev hloov kho rau cov4-bromo-1-indanoneTus qauv cuam tshuam rau nws cov haujlwm roj ntsha roj ntsha.
- Siv cov kev tshawb fawb ua kom zoo rau cov khoom ua kom zoo rau cov compound rau qhov zoo dua potency, xaiv, thiab cov khoom siv pharmrophetic.
Mechanism ntawm Kev Kawm Ua Haujlwm
- Elucidating qhov tshwj xeeb molecular txheej los uas muaj zog nws cov kev cuam tshuam roj ntsha.
- Kev txheeb xyuas cov tshuaj uas muaj peev xwm ua yeeb yam - Lub hom phiaj kev sib cuam tshuam thiab downstream signaling txoj kev cuam tshuam los ntawm qhov sib txuas.
Preclinical thiab kev kho mob
- Kev nce qib los ntawm kev tshawb fawb los ntawm kev tshawb fawb preclinical los tsim nws cov kev ua tau zoo thiab kev nyab xeeb hauv cov qauv tsiaj.
- Pib cov kev sim tshuaj ntsuam mob los ntsuas qhov kev nyab xeeb ntawm kev nyab xeeb thiab kev ua tau zoo hauv tib neeg, thaum kawg ua rau muaj feem tau cai kev tswj hwm kev pom zoo thiab kev ua lag luam.
Catalyst thiab khoom siv science
OLAIN POLYMERIZE CATALYST
Vim nws cov qauv tshuaj tshwj xeeb, tuaj yeem siv los ua ligand hauv ank polerances catalysts. Daim ntawv thov kev haus luam no nws muaj peev xwm cuam tshuam nrog hlau ions thiab ruaj khov lub chaw ua haujlwm catalytic nquag.
- Indanone derivatives tuaj yeem ua haujlwm ntau yam hauv kev tsim qauv hauv kev tsim qauv thiab cov khoom siv ntawm cov khoom ua kua roj tshiab.
- Qhov pom tau lub nplhaib cov qauv ntawm Indanone derivatives muaj kev sib npaug ntawm rigidity thiab yooj ntawm qhov xav tau qhov xav tau ntawm mesomorphic (ua kua crystalline) cov khoom.
- Cov lus qhia ntawm tshwj xeeb chaw, xws li bromine, cooking lub qhov muag thiab hluav taws xob ntawm cov khoom siv ua kua crystal.
- Cov khoom no yog qhov tseem ceeb rau kev siv cov lus qhia nyob rau hauv cov lus qhia, qhov uas zoo li Birperotropy, thiab kev txhuam khoom yuav tsum tau ua tib zoo tswj hwm.
- Indanone derivatives tuaj yeem pab txhawb rau qhov muaj kev ruaj khov ntawm ntau yam Mesomorphic theem, xws li nematic, smeces, thiab kab xej.
- Lub peev xwm los tswj cov theem mesomorphic tshwj xeeb yog qhov tseem ceeb rau kev ua tiav cov kev ua tau zoo hauv cov khoom siv ua kua crystal.
- Tus qauv tshuaj ntawm indanone derivatives yuav cuam tshuam cov molecular dlhos thiab xaj nyob rau hauv cov khoom ua kua crystal.
- Cov txheej txheem tsim nyog thiab cov kev txiav txim siab yog qhov tseem ceeb rau kev ua tiav siab- cov ncauj lus zoo nrog cov khaub ncaws hnav thiab qhov tsis zoo {1} dawb textures.
Lus Qhia
Txhim kho cov ntaub ntawv siv ua kua siv lead ua kua tuaj yeem ua rau muaj kev ua tau zoo hauv LCDs, xws li ntau dua cov sijhawm teb ntau dua, thiab saib dav dav.
Kho qhov chaw kho qhov muag
Ua kua crystal cov ntaub ntawv nrog cov khoom siv kho tshiab tuaj yeem siv nyob rau hauv kho kab ke rau kev sib txuas lus rau kev sib txuas lus thiab cov ntaub ntawv kev sib tham.
Optoelectronic li
Indanone -}} dered ua kua muaju tuaj yeem nrhiav tau cov ntawv thov hauv cov roj crystal, photonic muaju, thiab lwm cov thev naus laus zis.
Indanone derivatives, muaj cov sijhawm zoo rau cov qauv tsim thiab hluavtaws ntawm cov kua roj ua kua tshiab nrog cov khoom siv hluav taws xob tshwj xeeb. Cov ntaub ntawv no muaj peev xwm los hloov kho cov me nyuam, hloov kho kho qhov muag, thiab lwm yam khoom siv Optoelectronic. Txawm li cas los xij, kov yeej cov kev cov nyom ntawm synthesis, cov cuab yeej siv tau, thiab ruaj khov yuav tsum tau paub txog cov kev sib txuas no hauv cov khoom siv ua kua Crystal.
Ua kua muaju
Hauv thaj chaw ntawm cov kua muaj kua, indanone derivatives, tuaj yeem ua lub luag haujlwm ntawm cov qauv tsim thiab cov khoom siv ua kua tshiab uas muaj cov khoom siv hluav taws xob tshwj xeeb.
Birefringence: Indanone derivatives tuaj yeem cuam tshuam rau cov birgeas kua muaju ua kua, uas yog qhov tseem ceeb rau kev ua kua siv lcstal qhia (lcds). High Birefringence tuaj yeem ua rau ci dua thiab tau txais txiaj ntsig ntau dua.
Refronction Index: Lub chaw ntsuas cov kua roj ua kua muaj peev xwm tuaj yeem hloov kho los ntawm kev teeb tsa tshwj xeeb, los ua kom zoo rau cov khoom siv kho qhov muag ntawm cov khoom siv.
Dielectric anyotropy: Lub dielectric anisotropy ntawm cov kua muaju txiav txim siab lawv cov lus teb rau hluav taws xob teb. Indanone derivatives tuaj yeem tsim los txhim kho lossis hloov kho cov cuab yeej no, ua rau hloov sijhawm nrawm dua thiab kev siv hluav taws xob qis hauv LCDs.
Kev coj ua: Tailoring the conductivity of liquid crystals can be important for applications in organic electronics, such as organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs).
Indanone derivatives tuaj yeem tswj cov theem mesomorphic tshwj xeeb (nematic, smecter) ntawm cov kua muaj kua, uas yog qhov tseem ceeb rau cov khoom siv sib txawv thiab Optoelectronic khoom siv.
Tsim thiab Synthesis Saib Xyuas
Molecular qauv qauv
Lub nplhaib tsis pom tseeb ntawm Indanone derivatives muab cov scaffactives muab cov lus qhia ntxiv rau ntau yam uas tuaj yeem zoo {}} heev} sua cov khoom siv hluav taws xob thiab hluav taws xob.
Kev ua hauj lwm
Cov pab pawg ua haujlwm tau tuaj yeem txuas nrog Indanone Core Core los yuam cov khoom tshwj xeeb, xws li txhim kho solubility, thermal stability, lossis photoresponeneness.
Chairality
Cov lus qhia ntawm chairal chaw rau hauv Indanone derivatives tuaj yeem ua rau kev tsim cov lcs ua kua, uas yog qhov tseem ceeb rau kev siv hauv Ferrroelectric ua kua thiab lwm chairal -}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} Cov thev naus laus zis tshwj xeeb.
1
Txhim kho cov ntaub ntawv siv ua cov siv lead ua kua tuaj yeem ua rau kev txhim kho ntawm tom ntej no lcds nrog txhim kho lub ci ci, sib piv, thiab saib cov ces kaum.
2
Indanone -} dered ua kua muaju yuav pom cov ntawv thov hauv oleds hauv cov khoom siv hluav taws xob uas ua rau cov khoom siv hluav taws xob uas yog qhov tseem ceeb.
3
Cov khoom ua kua crystal nrog cov khoom siv kho tshiab tuaj yeem siv rau hauv photonic siv, xws li hloov kho qhov muag, modulators, thiab sensors.
Kev Tshawb Nrhiav thiab Kev Loj Hlob
Kev Tshawb Nrhiav Kev Tshawb Fawb
Ua ib tus tswv cuab ntawm tsev neeg Indanon, nws yog qhov txaus siab rau kev tshawb fawb mus rau nws cov kev ua haujlwm muaj peev xwm. Cov kev tshawb fawb yuav tsom rau nws cov kev cuam tshuam ntawm cov txheej txheem cellular, xws li muaj kev sib txawv, lossis ua kom muaj kev siv rau hauv kev kho mob ntawm cov kab mob.
Tshuaj Lom Tshuaj Synthesis
Cov kws tshawb nrhiav kuj tseem nyiam tshawb xyuas cov txheej txheem tshiab thiab txuag tau rau synthesis. Qhov no suav nrog cov tshuaj tiv thaiv zoo, xaiv cov catalysts tsim nyog, thiab txhim kho cov qoob loo thiab muaj kev nyab xeeb.
Cov qauv tshuaj thiab cov khoom
Tus lej lej: 15115-60-3
Molecular Cov Lus: C₉H₇BRO
Molecular hnyav: 211.06
Lub cev lub cev:
Zog: daj ntseg daj
Melting taw tes: 95-99 degree
Boint Taw tes: 304.1 Degree (760 MmHg)
Ceev: 1.608 g / cm³
Solubility: Tsis tau teev rau cov kuab tshuaj tshwj xeeb, tab sis cov khoom siv hluav taws xob organic feem ntau yuav tsum xaiv cov kuab tshuaj raws li cov neeg xav tau.
Core Manufacturing txheej txheem
Synthesis txoj kev
Txujctric:
Synthesis ntawm 3- (2-bromophenyl) prof acid:
Cov kauj ruam cov ntsiab lus: 3 {- (2-bromophenyl) prof acidizationization conditions conditions conditions ((xws li TrifluoromShanesulfonic Acid) los ua 4-brom-1-indone.
Tos: kwv yees li 77% (qee yam kev mob tuaj yeem cuam tshuam rau cov txiaj ntsig).
Synthesis ntawm 1-indone bromination tiv thaiv:
Cov Kauj Ruam: 1-indone yog brominated ntawm ib txoj hauj lwm tshwj xeeb (C-4) nrog brominating tus neeg sawv cev (xws li brominating tus neeg sawv cev (xws li brominating tus neeg sawv cev (xws li bromine) los tsim cov khoom lag luam.
Cov ntsiab lus tseem ceeb: Cov kev tawm tsam yuav tsum tau tswj kom tsis txhob muaj ntau {{brominary lossis isomer tsim.
Txheej txheem optimization cov ntaub ntawv
Microwave - pab synthesis:
Siv cov ntxhiab aldomatic aldehyde, 4- bromomethyl-3-}
Hom tau txais txiaj ntsig: Sij hawm luv luv (cov cua sov tsoos dej yuav tsum tau ob peb teev, microwave tsuas yog xav tau feeb) thiab siab tawm los.
Greenstage Txoj Kev:
Siv cov poov tshuaj ferrynide ua cov cyanide catalyst, 4-caladium catalyst, 4-cyanomethyl-1-cyanomethyl-1-Brom-1-indone) tau npaj tau zoo.
Hom tau txais txiaj ntsig: Yooj yim tshaj tawm - kev kho, siab tag nrho cov txiaj ntsig, tsim nyog rau kev tsim khoom lag luam.
Tswjhwm Thiab Cov Qauv
Yuav Tsum Purity:
Muaj Qib Kawm: Ntau dua lossis sib npaug rau 97%
Reachent qib: ntau dua los yog sib npaug rau 98% (qee tus neeg xa khoom muab 99% PURIE cov khoom lag luam).
Txoj kev kuaj pom:
Melting taw tes txiav txim siab: Txheeb xyuas cov kev coj dawb huv ntawm cov siv lead ua (tus qauv txheem: 95-99 degree).
Chromatographic tsom xam: saib xyuas cov ntsiab lus ntawm impurities siv HPLC lossis GC.
Kev txheeb xyuas theem pib: paub meej tias cov ntsiab lus ntawm C, H, Br, thiab o muaj txoj kab nrog theoretical qhov tseem ceeb.
Kev Nyab Xeeb Kev Nyab Xeeb thiab Kev Tiv Thaiv Kev Nyab Xeeb
Cov phom sij:
GHS kev faib tawm: Lus ceeb toom (H302: Kev noj khoom haus yog qhov muaj kev phom sij; H319: Ua rau lub qhov muag khaus loj me).
Yuav tsum muaj cov kev ua haujlwm:
Hnav cov hnab looj tes tiv thaiv kev tiv thaiv, tsom iav, thiab sim lub tsho loj.
Zam kev nqus plua plav lossis chav. Tsis txhob ua haujlwm thaum noj mov, haus, lossis haus luam yeeb.
Khib Nyiab:
Muab cov ntsiab lus pov tseg thiab ntim raws li cov cai hauv zos kom tsis txhob muaj kuab paug ib puag ncig.
Cim npe nrov: 4-Bromo-1-Is Nrias teb CASE 15115-60-3, cov neeg tsim khoom, chaw tsim khoom, Hoobkas, yuav, nqe, loj, rau muag