4- methoxyphphenylacetone, ib qho tshuaj organic nrog cov qauv molecular: C10H12O2, lub cev hnyav molecular yog 164.201, thiab tus lej acccession acccession naj npawb yog}. Nws qhov cub npau npau yog 268 degree, melting point yog {{}}} degree, thiab cov ntawv sau ua kom zoo nkauj yog 1.5251. Nyob rau hauv chav tsev kub thiab siab, nws yog cov kua daj uas yog insoluble hauv dej tab sis sollubs hauv cov etyl acetate, dihloromete, thiab chloroform. Qhov no compound ntawv nplua nuj hluav taws xob huab cua sov thiab tseem ceeb fluorescence cov qauv, ua rau nws cov ntaub ntawv tseem ceeb ntawm cov khoom siv hauv organic thiab kev npaj cov khoom siv Orgi.
Cov qauv no muaj cov alkyl hloov cov carbonyL chav tsev, uas muaj cov khoom siv hloov khoom zoo. Nws tuaj yeem yauv nucleophilic sib ntxiv nrog nucleophilic reagents xws li reagents reagents, thiab tseem tuaj yeem tiv thaiv kev sib xyaw nrog amine derivatives kom tau txais imine derivatives. Tsis tas li ntawd, metroxy, vim muaj zog electron tsis pub muaj cov pab pawg hluav taws xob, ua kom muaj kev sib txuas hluav taws xob, ua kom muaj kev sib txuas ua ke thiab ntau haiv neeg. Piv txwv li, nws tuaj yeem hloov kho los ntawm kev ua haujlwm hloov dua siab tshiab, xws li mexoxy tau oxidized rau cov carboxyl lossis txo rau hydroxyl, yog li synthesizing ntau hom phenylacetone compounds.

|
Tshuaj Cov Qauv |
C10H12O2 |
|
Muaj pes tsawg leej |
164 |
|
Molecular hnyav |
164 |
|
m/z |
164 (100.0%), 165 (10.8%) |
|
Kev Ntsuam Xyuas |
C, 73.15; H, 7.37; O, 19.49 |
|
|
|

4- methoxyphphenylacetoneYog lub teeb ci daj ntawm chav sov thiab lub zog, insoluble hauv dej tab sis soluble hauv cov etyl acetate, dihlorometaine, thiab chloroform. Vim muaj zog Electron pub nyiaj ntawm cov pab pawg methoxy, thiab muaj ntau cov kev siv hluav taws xob ntawm cov orgientthess chemistry thiab kev npaj ntawm cov ntaub ntawv muaj zog.
Methoxyphyphenylacetone muaj ntau cov ntawv thov, feem ntau yog cov tshuaj, tshuaj tua kab, ntshav, tshuaj pleev ib yam, thiab lwm yam, thiab lwm yam.

Tshuaj Nruab Nrab Hluav Taws Xob:
Methoxyphyphenylacetone yog qhov nruab nrab tseem ceeb rau cov lus ntawm ntau yam tshuaj. Piv txwv li, cov yeeb tshuaj formoterol, uas tuaj yeem siv los ua ke thiab kho mob ntsws, thiab lwm yam kev mob ntsws ua rau cov tshuaj prenylamine lactate, uas tuaj yeem siv los kho angina pectoris. Nws cov qauv tshuaj tshwj xeeb cov qauv thiab cov khoom ua rau Methoxyphyphenylacetone ib feem tsis tseem ceeb ntawm cov khoom siv hluav taws xob.
Organic synthesis:
Lub tsev carboryl hloov nrog ib pab pawg alkyl hauv cov qauv methoxyphenylacetone muaj cov tshuaj lom neeg hloov roj thiab muaj peev xwm hloov ntau yam kev hloov pauv. Piv txwv li, nws chav tsev carbonyl tuaj yeem txuas ntxiv nucleophilic reagents xws li cov tshuaj tiv thaiv condensation xws li amine ua ke kom tau txais imine derivatives. Ntxiv rau, methoxyphenylacetone kuj tuaj yeem hloov kho ntawm kev ua haujlwm hloov dua siab tshiab, xws li meTHEXY tau txais kev hloov pauv, oxidized rau carboxyl lossis txo rau hydroxyl. Cov kev tawm tsam no tuaj yeem siv los ua ke sib txawv phenylacetone tebchaw, nthuav lawv cov ntawv thov hauv Organi synthess thiab Orgernal cov ntaub ntawv ua haujlwm.
Cov txuj lom thiab cov khoom noj ntxiv khoom noj ntxiv:
Methoxyphyphenylacetone, vim nws cov cim aroma thiab tsw, tuaj yeem siv hauv cov txuj lom thiab cov zaub mov tshwj xeeb los muab cov khoom noj muaj ntxhiab tshwj xeeb thiab saj rau cov khoom noj, dej haus, thiab lwm yam khoom lag luam. Nws muaj kev nyab xeeb thiab cov yam ntxwv muaj txiaj ntsig thiab cov tshuaj lom li cas ua rau methoxyphenyphenyphenyl acetone muaj kev cia siab thov kev lag luam hauv kev lag luam khoom noj.

1. Kws ua teb
Cov synthesis ntawm Pentroerol:
Methoxyphyphenylacetone yog qhov nruab nrab tseem ceeb rau cov lus ntawm Picterol. Fumatrol yog ib tug neeg ua haujlwm ntev ntev tau siv los kho kev ua pa nyuaj los ntawm mob ntsws, thiab lwm yam mob. Los ntawm kev hloov kho cov tshuaj lom neeg thiab kev hloov pauv ntawm methoxyphphhylacetone, cov tshuaj ua kom muaj tshuaj tseem ceeb tau. Txoj kev synthess tshwj xeeb suav nrog alkration, hws, thiab lwm yam kev tawm tsam ntawm P-mex mexyphenylacetone mus rau thaum kawg tau txais Pysterol.
Synthesis ntawm lactic acid cyclidine:
Methoxyphyphyphenylacetone kuj tseem tshuav tseem ceeb hauv cov lus sib npaug ntawm LACTOFERRIN. Lactic acid ıgine yog calcium channel blocker siv los kho angina pectoris. Thaum lub sij hawm nws cov txheej txheem synthess, methoxyphenylacetone reacts nrog lwm yam tshuaj lom neeg tshuaj ntxuav, xws li thaum kawg tau txais cov tshuaj lactate cardiet.
2. Organic synthesis teb
Synthesis ntawm imine derivatives:
Lub CarbonyL chav ntawm methoxyphenylacetone tuaj yeem tsim nrog amine compounds kom tau imine derivatives. Cov tshuaj tseem ceeb no muaj cov ntawv thov tseem ceeb, xws li cov tshuaj catalysts, thiab lwm yam los ua cov txiv neej sib txawv.
Synthesis ntawm chiral cawv thiab chiral amine compounds:
Los ntawm kev siv cov khoom hloov pauv ntau yam ntawm CarboronyL pab pawg, methoxyphphenylacetone tuaj yeem siv los npaj chiral cawv thiab chiral amine compounds. Cov tebchaw muaj ntau cov kev siv nyob rau hauv cov qauv tshuaj, tshuaj tua kab, thiab lwm yam.
3. Txuj lom thiab zaub mov ntxiv
Tsiaj Txuj Ci:
Vim tias nws cov tshuaj tsw qab, P-methoxyphphenylacetone tuaj yeem siv cov ntxhiab tsw tshwj xeeb rau cov tshuaj tsw qab rau cov tshuaj tsw qab, etc. etcials thiab lwm yam kev nyab xeeb siv tau nyob rau hauv kev lag luam tus ntxhiab.
Cov Khoom Noj Ntxiv:
Methoxyphyphyphenylacetone kuj tseem siv tau ua khoom noj khoom haus ntxiv rau hauv cov dej haus, khoom qab zib, muab cov khoom noj tshwj xeeb thiab tsw. Nws cov cim aroma thiab tsw ua raws li methoxyphenyl acetone dav siv hauv kev lag luam khoom noj.

Synthesis txoj kev ntawm4- methoxyphphenylacetone:
Nws yog ib qho tseem ceeb kws tshuaj paus siv hauv kev tsim cov tshuaj ua pa ua pa, nrog rau cov tshuaj phenyris, thiab cov pa roj ntsha, cov tshuaj philes
Tam sim no, cov khoom lag luam tsis tau muaj peev xwm nyob hauv Suav teb, thiab nws txoj kev huv yog tsuas yog 95%, uas tsis tuaj yeem ua tau raws li kev xav tau lag luam. Raws li cov ntawv sau, peb tau kawm cov lus sib txawv ntawm kev lag luam, tshem tawm cov khoom siv dodillen, thiab tom qab ntawd ua rau cov khoom siv raw p-methoxydehdehde kom tau cov khoom tsim nyog. Cov txheej txheem tau yooj yim, cov khoom lag luam zoo yog txhim kho (kev coj dawb huv yog ntau tshaj li 98%), thiab cov txiaj ntsig yog ntau dua 80%. Nrog p-methoxybenhaldehyde li cov khoom siv roj hmab, sodium metrium carbonate catalonate catalteration los tsim lub nplhaib, thiab nruab nrab yog hydrolyzed tsis muaj kev sib cais kom tau txais cov khoom lag luam.

Ib qho tawm ntawm-ntawm-tank Electrochemical cov qauv ntawm P-methoxyphphenylacetone:
Nws belongs rau tom teb ntawm Electrochemical Technology. Hauv ob-chamber electrolytic cell, platinum xaim yog siv los ua cov ntaub ntawv me me, tshuaj activ ib leeg yog siv cov roj ntsha uas tsis muaj zog ntxiv los ua cov tshuaj electrolysis siv tau los ua cov khoom siv hluav taws xob ntxiv rau kev siv Tetraacetate. Tom qab electrolysis nres, cov hmoov txhuas tetraacetate tau txais yog ntxiv rau lub siab. Tom qab cov tshuaj tiv thaiv, uas yog organic cov khoom yog tau, uas yog hydrolyzed los ntawm cov sulfuric acid thiab muab rho tawm los ntawm ether kom tau cov khoom, p-methoxyphphenylacetone. Cov coj ua raws li tau txais tom qab kev kho mob tuaj yeem rov ua dua tshiab thiab rov siv dua. Cov txiaj ntsig ntawm cov txheej txheem synthess yog 52 ~ 62%. Lub tswv yim muaj qhov zoo ntawm kev yooj yim thiab yooj yim rau cov tshuaj tiv thaiv cov ntaub ntawv nyoos, kev ua haujlwm loj, muaj txiaj ntsig zoo thiab tus nqi qis. Nws yog tus nqi muaj nuj nqis ntxiv txoj kev.
Ib qho hauv-tank electrochemical synthesis txoj kev ntawm4- methoxyphphenylacetone:
Nws belongs rau tom teb ntawm Electrochemical Technology. Hauv ob-chamber electrolytic cell, platinum xaim yog siv los ua anode, acetic acid-acetic anhetate yog cov kuab tshuaj, thiab cov poov tshuaj acetate raws li kev txhawb nqa electrolyte. Ntawm qhov ntsuas kub, hauv catode chamber ntawm electrolytic off electrolysis, thaum lub sij hawm tsis tshua muaj hluav taws xob hloov kho ib txhij, tom qab txiav tawm electrolysis, tus Tau txais cov khoom muaj organic yog hydrolyzed los ntawm sulfuric acid thiab txuas ntxiv kho kom tau txais cov khoom, p-methoxyphphenylacetone. Lub tswv yim muaj qhov zoo ntawm kev yooj yim thiab yooj yim rau cov tshuaj tiv thaiv cov khoom nyoos, kev ua haujlwm loj, siab tus nqi, thiab yog tus nqi qis-ntxiv cov txheej txheem kev.
Cov Qauv Hluav Taws Xob
Muaj ob txoj kev tseem ceeb rau synthesizing methoxyphenylacetone: cov qauv kev npaj khoom lag luam thiab cov qauv hluavtaws hauv hluav taws xob ntsuab.
Tsoos kev npaj npaj:
Feem ntau, {3- hydroxyphenylacetone yog reacted nrog Ditethyl sulfate. However, this method has disadvantages such as high cost, multiple by-products, low yield, and high toxicity of dimethyl sulfate, which limits its industrial production.
Ntsuab hluavtaws qauv:
Txhawm rau hais txog qhov tsis txaus ntseeg ntawm cov txheej txheem ib txwm muaj, cov kws tshawb nrhiav tau npaj siab rau ib qho kev ua suab ntsuab synthesis. Cov qauv no cuam tshuam nrog kev ntxiv cov hmoov hlau magnesium thiab anhydrous aluminium trichloride rau cov reactor nruab nrog cov condenx condenser thiab kev poob siab. Los ntawm maj mam ntxiv cov tshuaj sib tov ntawm M-methopromobzene thiab tetrahydrofuran (qhov kub ntawm cov tshuaj tiv thaiv nruab nrab ntawm lub xeev {1} degree kom muaj kev tswj hwm me ntsis. Tom qab dentwise ntxiv, ua kom sov thiab reflux rau {}}}} Tom qab, maj mam ntxiv acetonitrile rau grampard reagent thaum stirent, thiab txuas ntxiv cov tshuaj tiv thaiv rau 1. {}}}}}. Tom qab cov tshuaj tiv thaiv tiav, 3Mol / l hydrochloric acid yog maj mam ntxiv dropwise nyob rau hauv ib tug dej txias da dej kom decompose ntxiv cov khoom. Tom qab distillation thiab lwm cov kauj ruam, P-methoxyphenylacetone thaum kawg tau txais. Hom qauv no muaj qhov zoo ntawm tus nqi qis, siab tawm los, thiab ib puag ncig kev ua phooj ywg, thiab yog qhov tsim nyog rau kev tsim khoom lag luam.
Cim npe nrov: 4- methoxyphenylacetone Cas 122-84-9, cov chaw muag khoom, chaw tsim khoom, yuav khoom, nqe, loj, rau muag




