D-Pipecolinic Acidyog ib qho tsis muaj kob lossis dawb crystalline hmoov uas zoo ib yam li cov khoom siv crystalline hauv tsos. Cov hniav nyiaj hniav ntsuab yog kwv yees li 129.15 g / mol, cas 1723-00-8, thiab cov mis roj ntsha yog C6h11NO2. Nws yog soluble nyob rau hauv dej thiab nws solubility yog cuam tshuam los ntawm kub thiab tus nqi. Nws cov dej solubility ntawm chav tsev kub yog kwv yees li 1g / 10ml. Tsis tas li ntawd, nws kuj tuaj yeem yaj nyob rau qee cov kuab tshuaj organic, xws li cawv, neeg muaj kev nyab xeeb, thiab cov khoom siv cov khoom siv. Nws lub qhov cub npau npau tsis tau tshaj tawm, raws li nws cov kev txiav txim siab kub yog qhov tsawg. Nws yog cov kab sib txuas khov kho nrog cov thermal decomposition kub siab dua nws lub taw tes melting. Txawm li cas los xij, cov khoom siv thermal decomposition xav tau kev tshawb fawb ntxiv thiab kev sim txiav txim. Nws yog chiral molecule nrog ob lub ecenerical isomers, D - thiab l -. Lub qhov muag hloov ntawm cov khoom yog [] d +8. 8 degree (siab 1, cov kuab dej). Nws muaj cov yam ntxwv nqus tau thiab tuaj yeem nqus cov teeb ultraviolet. Nws yog acidic thiab muaj pka tus nqi ntawm kwv yees li {13}}. Hauv dej, nws ionizes los ua hydrogen ions, ua cov tshuaj acidic. Nws muaj cov ntawv thov dav dav hauv cov liaj xws li cov tshuaj siv tshuaj yeeb, cov khoom siv tshuaj tua kab, cov khoom siv roj av, kev tshawb fawb txog kev tshawb fawb txog kev tshawb fawb, thiab kev tshawb fawb biochemical. Nws ntau haiv neeg thiab cov khoom siv sib txawv ua rau nws cov kev tshawb fawb tseem ceeb hauv ntau lub teb ntawm cov tshuaj lom neeg thiab tshuaj lom neeg.
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Tshuaj Cov Qauv |
C6h11No2 |
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Muaj pes tsawg leej |
129 |
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Molecular hnyav |
129 |
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m/z |
129 (100.0%), 130 (6.5%) |
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Kev Ntsuam Xyuas |
C, 55.80; H, 8.58; N, 10.84; O, 24.77 |
Cov ncauj lus kom ntxaws ntawm cov qauv molecular ntawmD-Pipecolinic Acid.
1. Tsib tug qauv Heterocyclic: Tus qauv tseem ceeb ntawm D-Pipecolic Acid yog ib tus qauv nitrogen atom, nthuav qhia ib puag ncig cov qauv zoo ib yam li ntawm Balaka Luav. Cov pa roj atoms thiab nitrogen atoms nyob rau hauv no heterocclic ntiv nplhaib tau npaj ua ntu zus los ntawm tus lej, nrog cov pab pawg sib txawv ntawm cov pa roj carbon atoms.
2. Cov pab pawg ua haujlwm tau:
-Carboxyl Group: D-pipecolinic Acid Molecule muaj cov pab pawg carboxyl (- cooh) nyob rau ntawm tus qauv heterocyclic. Cov pab pawg carboxyl yog tsim los ntawm cov pab pawg carbonyl (c {}}}} om, uas txuas nrog cov pa roj carbon aus los ntawm kev sib raug zoo.
-Amino pab pawg: hauv d-pipecolinic acid molecule, tseem muaj cov amino pab pawg (- NH2) nyob rau ntawm tus qauv Heterocyclic. Cov amino pab pawg yog tsim ntawm ib nitrogen atom thiab peb hydrogen atoms. Cov nitrogen atom txuas nrog cov pa roj carbon atom los ntawm kev sib khi sib khi.
-Thaum pab pawg Alkyl: Qhov thib ob cov pa roj hmab atom nyob rau hauv ib pab pawg acid, qhov twg ob pab pawg ua haujlwm txuas nrog los ntawm kev sib qhia cov pa roj carbon carbon ib leeg. Qhov no CIKyl pab pawg tuaj yeem ua cov pab pawg sib txawv, xws li methyl (ch3) lossis ethyl (C2h5).
3. Spatial configuration: Cov pa roj teeb thiab nitrogen atom nyob rau hauv heterocyclic acid yog ob lub ntiaj teb kev teeb tsa, uas yog, lawv cov kev sib koom tes ntawm tib neeg. Tsis tas li ntawd, cov pab pawg Cis Alkyl hauv D-Pipecolinic Acid Molecule nyob ntawm ib sab ntawm Heterocyclic dav hlau.
4. Muaj nuj nqi thiab cov khoom: D-pipecolinic acid yog cov acidic compound uas tuaj yeem tso cov yeeb yam (h +) los ntawm cov pab pawg carboxyl. Nws ua lub zog tseem ceeb hauv kev muaj sia nyob hauv cov tsiaj muaj sia, xws li yog ua ntej ntawm cov alkaloid thiab koom nrog protein synthesis, cov metabolism, thiab decomposition cov txheej txheem. Ib qho ntxiv, nws yuav muaj lwm cov kev muaj peev xwm muaj peev xwm thiab cov teebmeem.
D-Pipecolinic Acid(CAS naj npawb: {{{1723-00-8) yog qhov sib xyaw nrog cov qauv tshuaj xws li biochemistry, kev tshawb fawb thiab kev ua liaj ua teb. Nws cov mis molecular yog c ₅ h ₉ tsis ₂, nrog molecular hnyav ntawm 115.13. Nws zwm rau cov tsis muaj protein amino acids thiab yog qhov nruab nrab tseem ceeb hauv Lysine Metabolism txoj hauv kev. Hauv qab no yog nws cov kev siv tseem ceeb:
Kev Siv Kho Mob: Dual Nqi ntawm kev kho thiab kuaj mob
Nws cov tshuab kev ua hauv pyridoxine nyob rau kis mob vwm tau kawm. High qib ntawm d-pipecliced acid tuaj yeem cuam tshuam nrog cov metabolism hauv gamma aminobutyric acid (Gaba), ua rau muaj kev qaug dab peg ntau thiab ua rau qaug dab peg. Yog li ntawd, d-pipecliced acid tau dhau los ua lub hom phiaj tseem ceeb rau pyridoxine muaj feem ntau mob ntsim. Los ntawm inhibiting qhov kev ua si ntawm gamma aminobutytric acid transaminase (gaba-t) nyob rau hauv lub hlwb yog nce, yog li exerting ib tug antiepilepteptic nyhuv. Hauv kev teb rau cov metabolic kev txawv txav ntawm D-Pipecico acid, piv txwv li cas, xws li {4 4} hydrentration hauv lub cev thiab kev mob epileps. Nyob rau hauv xyoo tsis ntev los no, nrog rau kev kawm tob ntawm cov kev sib tw metabolic ntawm d-pipeclic acid, tshiab hom tshuaj tiv thaiv cov tshuaj tau tshwm sim tsis tu ncua. Piv txwv li, los ntawm kev tswj hwm cov metabolic enzymes ntawm d-pipecico acid, ntau yam kho cov teebmeem tuaj yeem ua tiav.
Kev tshawb fawb txog cov tshuaj tua kab mob
Ua ib nrab hauv nruab nrab hauv Lysine metabolism, nws cov kev sib tw metabolism yog ua ntej cov tshuaj tua kab mob, xws li cov kab mob bacteriocins. Los ntawm kev tswj hwm nws cov metabolism, cov tshuaj tua kab mob biosynthetic ntawm cov tshuaj tua kab mob tuaj yeem txhim kho, muab cov tswv yim tshiab rau kev txhim kho cov tshuaj tua kab mob. Cov kws tshawb fawb siv noob tshuab kho kom haum thev naus laus zis los tswj cov kab ke tseem ceeb, yog li piperidine reductase ntau lawm, yog li ua kom cov tshuaj tua kab mob loj loj. Raws li cov qauv txheej txheem ntawm D-Pipecico acid, cov kws tshawb nrhiav tau tsim ntau cov neeg tua kab tshiab. Cov neeg sawv cev tua kabmob uas tau ua rau lawv cov kabmob tshuaj tiv thaiv kab mob los ntawm kev cuam tshuam nrog cov kab mob ntawm tes lossis cov khoom siv protein. Nrog rau kev kawm tob ntawm cov teeb meem metabolic ntawm d-pipecic acid, nws yuav tau tsim kho tshiab hauv ntej, muab kev xaiv ntau rau kev kho mob.
Nws cov kev txawv txav metabolic yog ze rau qhov tshwm sim thiab kev loj hlob ntawm ntau yam kab mob metabolic. Piv txwv li, hauv phenylketonuria, cov neeg mob tau nce qib ntawm D-Pipecico acid nyob rau hauv lawv lub cev, ua rau muaj kev puas tsuaj ntawm neurological. Cov kws tshawb nrhiav tau tsim ntau yam cov tswv yim kho mob rau cov kab mob metabolic los ntawm kev tsis sib thooj ntawm cov kua txob d-pipecic. Piv txwv li, ntxiv rau cov vitamin B6 tuaj yeem txhawb cov metabolism hauv d-pipecliced acid, txo nws cov kev xav hauv lub cev, thiab muaj cov tsos mob ntawm cov kab mob. Tsis tas li ntawd, inhibitors lossis cov kev ua kom pom cov khoom siv metabolic tshwj xeeb kuj tseem tuaj yeem siv los tswj cov kev sib tw metabolic ntawm d-pipecico acid. Hauv kev kho mob phenylketonuria, txwv txoj kev nkag mus rau cov vitamin B6 tuaj yeem txo qis qib d-pipeclicated acid thiab txhim kho cov kev lag luam metabolic ntawm cov neeg mob.
Cov ntawv thov kev ua liaj ua teb: Cov kev cai ntawm kev cog ntoo thiab kev ntxhov siab tsis kam
Nws yog qhov tseem ceeb hauv lysine metabolism hauv cov nroj tsuag, thiab nws cov ntsiab lus yog tswj hwm los ntawm ntau yam kev ntxhov siab, suav nrog rau kev txhim kho theem. Kev tshawb fawb tau qhia tias D-Pipecico acid tau koom nrog hauv Nitrogen Metabolism Cov Pathways hauv cov synthesis ntawm cov amino acids, protein, thiab nucleic acids. Tsis tas li ntawd, raws li ib tug ua ntej ntawm cov metabolites thib ob, nws koom nrog synthesis ntawm cov nroj tsuag tiv thaiv xws li lignin thiab flavonoids. Nws tau kos duab molecular muaj nuj nqi nyob rau hauv tsob nroj lub cev, koom nrog txoj cai ntawm cov nroj tsuag kev loj hlob, kev txhim kho, thiab kev nyuaj siab teb. Piv txwv li, hauv cov txheej txheem xav tau - SAR), D-pipecliced acid ua hauj lwm raws li tus tseem ceeb piav qhia dav dav-}}} pipecic acid regulatory. Ib qho ntxiv, nws tseem koom rau hauv kev tswj cov nroj tsuag muaj kev tswj hwm kev ua haujlwm xws li cov phiajcim (sa) Raws li kev lom neeg muaj txiaj ntsig, nws tuaj yeem txhawb nqa cov nroj tsuag kev loj hlob, txhim kho kev ua kom muaj kev ua kom muaj txiaj ntsig zoo, thiab txhim kho kev nyuaj siab tiv thaiv. Nws tswj cov khoom siv metabolism, ua kom zoo dua lub zog ua haujlwm, thiab ua rau cov nroj tsuag kom muaj kev ua haujlwm nyob rau hauv cov kev tshwm sim hauv lub cev. Piv txwv li, exgenous application ntawm d-pipeclicated acid tuaj yeem txhawb nqa hauv paus txhim kho hauv paus, txhim kho cov antioxymant enzyme, yog li txhim kho tag nrho cov nroj tsuag kev ntxhov siab tiv thaiv.
Daim Ntawv Thov hauv Cog Kev Txhim Kho Kev Cai
Lub hauv paus system yog lub qhov khoom nruab nrog rau cov nroj tsuag kom nqus dej thiab cov as-ham, thiab nws txoj kev loj hlob cuam tshuam rau cov nroj tsuag kev loj hlob thiab kev ntxhov siab tsis kam. Kev tshawb fawb tau pom tias nws tuaj yeem txhawb cov ntsiab lus hauv paus ntawm tes thiab ua rau cov hauv paus cov plaub hau ntom ntom hauv paus, yog li txhim kho hauv paus nqus lub peev xwm. Piv txwv li, hauv cov noob taum noob, {{{}}. 5 hli d-pipeclic acid tuaj yeem nce germination tus nqi los ntawm 12% thiab cov noob tshiab tshiab ntawm 18%. Cov nyhuv no yuav cuam tshuam nrog nws cov kev cai ntawm cov nroj tsuag hormone tshuav nyiaj li cas, kev txhawb nqa ntawm tes faib thiab elongation. Photosynthesis yog cov txheej txheem tseem ceeb ntawm lub zog metabolism hauv cov nroj tsuag, thiab nws cov kev ua tau zoo cuam tshuam rau cov nroj tsuag kev loj hlob thiab tawm los. D-pipecliced acid tuaj yeem txhim kho cov khoom lag luam rub tawm los ntawm kev nce Rubrisco enzyme, txhawb nqa chlorophyl synthesis, thiab kev ua kom pom lub teeb hluav taws xob kev siv tau zoo. Piv txwv li, foliar txau ntawm 100 mg / l d-pipecic acid thaum lub txiv hmab paj tawg tuaj yeem nce ib leeg txiv hmab txiv ntoo muaj zog txog 18% thiab cov vitamin C Cov Ntsiab Lus los ntawm 22%. Cov nyhuv no yuav cuam tshuam nrog cov kev cai ntawm cov nroj tsuag carbon thiab nitrogen meatolism sib npaug thiab kev txhawb nqa ntawm assimilate kev sib txuam los ntawm D-Pipecico acid. Cov tshuaj hormones cog ua si ib lub luag haujlwm tseem ceeb hauv kev cog tsob ntoo, kev txhim kho, thiab cov lus teb muaj kev ntxhov siab.
Drought yog ib qho ntawm cov kev tsim txom loj uas txwv kev cog qoob loo thiab tawm los. Nws tuaj yeem txhim kho cov nroj tsuag tiv thaiv kev tiv thaiv los ntawm kev tswj hwm cov nroj tsuag roj metabolism, txhim kho cov kev sib txuam ua ke, thiab kev txhawb nqa ntawm cov tshuaj Osmoregulatory. Piv txwv li, cov nplej noob qoob loo ua ntej ua ntej nrog 100 μ m Cov nyhuv no yuav cuam tshuam nrog nws cov kev cai ntawm ABA taw qhia txoj hauv kev, kev nce qib ntawm kev kaw cov dej sib txawv, thiab txo cov dej ntawm cov dej evaporation. Ntsev kev ntxhov siab yog lwm qhov tseem ceeb tseem ceeb kev ntxhov siab uas cuam tshuam rau cov nroj tsuag kev loj hlob thiab tawm los. D-pipeclicic acid tuaj yeem txhim kho cov khoom ntsev txhim kho los ntawm kev tswj hwm tsob ntoo ion, txhim kho cov kev sib txuam ntawm osmegulatory tshuaj. Piv txwv li, cov txhuv kho nrog D-Pipecico acid nyob rau hauv ntsev kev nyuaj siab pom tias 30% nce rau biomass thiab 40% txo nyob rau hauv na + acpectulation. Cov nyhuv no yuav cuam tshuam nrog nws cov kev cai ntawm na + / k + thauj neeg, nce qib ntawm na + efflux, thiab k - nqus.
DAIM NTAWV THOV HAUV KEV UA HAUJ LWM RESHANCING
Tsis tshua muaj kev ntxhov siab kub tuaj yeem ua rau cov qauv kev puas tsuaj thiab kev ua haujlwm ntawm CL tsob nroj ntawm cov nroj tsuag mis, cuam tshuam rau cov nroj tsuag kev loj hlob thiab tawm los. Nws tuaj yeem txhim kho cov nroj tsuag txias tsis kam los ntawm kev sau qoob loo ntawm cov nroj tsuag membrane, txhim kho antioxidant enzyme kev ua si, thiab txhawb nqa cov ntsiab lus ntawm tus mob khaub thuas resistant noob. Piv txwv li, lws suav seedlings kho nrog D-Pipecico acid tau qhia txog MDA cov ntsiab lus thiab txo qis kev puas tsuaj rau cov kev ntxhov siab tsawg. Cov nyhuv no yuav cuam tshuam nrog nws cov kev cai ntawm cov khoom siv roj actilated tsis zoo, thiab txhim kho cell membrane tsis muaj peev xwm. Cov kab mob cog yog ib qho tseem ceeb cuam tshuam rau kev ua liaj ua teb. D-pipeclicated acid tuaj yeem txhim kho cov kab mob cog tsam los ntawm kev tswj cov khoom tiv thaiv cov khoom siv hluav taws xob pom zoo, thiab txhim kho lub zog ntawm phab ntsa zog. Piv txwv li, nws tuaj yeem tsim cov ntoo tsim los tsim cov tshuaj tiv thaiv xws li cov kab mob protein (preasins -s, thiab flimonoids, uas inhibit txoj kev loj hlob thiab kis tau tus kab mob ntawm pathogens. Ntxiv rau,D-Pipecolinic Acidtuaj yeem txhim kho cov nroj tsuag uas tau txais - sar) los ntawm kev tswj cov nroj tsuag muaj kev tawm tsam cov kev tawm tsam cov kev sib tw nrog SA, JA, thiab lwm yam.
Cim npe nrov: D-Pipecolinic Acid Cas {{}}}, cov chaw muag khoom, chaw tsim khoom, Hoobkas, yuav, nqe, loj, rau muag