Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov chaw muag khoom ntawm n {}} piperidone CAS 98977-34-5 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale mis siab zoo n-boc-3-carboetoxy-4-piperidone CAS 98977-34-5 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Zaj tshaj tawm
Peb tsis txhob muab txhua yam tshuaj ntawm piperidine series, txawm tias muaj peev xwm tau txais piperidine lossis piperidone chemcials!
Tsis muaj teeb meem nws txwv lossis tsis! Peb tsis muab!
Yog tias nws nyob hauv peb lub Webiste, nws tsuas yog rau xyuas cov ntaub ntawv ntawm cov tshuaj sib txuas.
Mar . 25 th 2025
N - boc-3-carboetoxy-4-piperidoneyog ib cov organic ntau ntau rau cov piperidones, muaj cov pab pawg ua ke uas tso ua ke nrog cov khoom siv hluav taws xob uas muaj txiaj ntsig zoo hauv cov khoom siv hauv Suav thiab cov tshuaj tua hluav taws xob. Cov molecule yog tus cwj pwm los ntawm lub nplhaib piperidine, uas yog rau- Nws tau muab tso rau ntawm cov leeg ua ke nrog ib qho kev sib tw ntawm cov qib siab. Pawg pab pawg BOC, feem ntau yog siv los ua pab pawg tiv thaiv hauv cov organic kev siv tshuaj chemistry, muab cov khoom ruaj khov thiab ua raws li cov tshuaj lom neeg ntxiv.
Qhov 3-txoj hauj lwm ntawm Piperidine nplhaib bears carboetoxy (Ethyy Ester cov haujlwm uas tuaj yeem nthuav tawm ntau yam kev hloov pauv estericy, ester txauv, lossis txo kom dej cawv. Meanwhile, 4-txoj hauj lwm yog nyob ntawm pab pawg Ketone, ib lub chaw muag khoom uas tuaj yeem cuam tshuam rau kev haus cawv, aldol hws, lossis Michael ntxiv.
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Tshuaj Cov Qauv |
C13h2no5 |
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Muaj pes tsawg leej |
271.14 |
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Molecular hnyav |
271.31 |
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m/z |
271.14 (100.0%), 272.15 (14.1%), 273.15 (1.0%) |
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Kev Ntsuam Xyuas |
C, 57.55; H, 7.80; N, 5.16; O, 29.48 |
N - boc-3-carboetoxy-4-piperidone, tseem hu ua 1 {{- boc-4-oxo-3-piperidinecarboxylic acid Nws cov qauv kev tshwj xeeb ua rau nws muaj txiaj ntsig zoo rau cov hluavtaws ntawm ntau cov chaw sawv cev. Hauv qab no yog qee cov piv txwv ntawm cov tshuaj lossis cov chav kawm tshuaj uas tuaj yeem ua cov khoom siv siv:
- Nyob rau hauv synthesis ntawm trypsin inibitors, uas muaj txoj haujlwm raws li anti {{ Cov neeg inhibitors no pab txo qis hauv ntau yam kev mob, suav nrog cov uas muaj kev cuam tshuam ntau dhau trypsin kev ua si.
- Qhov sib xyaw ua ke kuj tseem muaj txiaj ntsig tseem muaj txiaj ntsig zoo nkauj ntawm Matrix Metalloproteinase (MMP) Inhibitors thiab Farnesylartorses inhibitors, ob leeg yog cov chav kawm tseem ceeb ntawm cov tshuaj antitumor. MMP inhibitors inhibit qhov kev tsis txaus siab ntawm extracellular matrix cov protein, uas feem ntau cuam tshuam nrog cov ncauj lus mob qog thiab metastasis. Cov neeg tsis muaj kev tiv thaiv Five
Ntxiv nrog rau nws siv hauv anti - cov tshuaj antive, nws cov tshuaj antitumorators, nws cov tshuaj antitumorators, nws cov derivatators tau raug kaw rau cov lus qhia txog cov molecules ntau, suav nrog:
- Gaba (- Aminobutyric Acid) Ruptors Acid) Ruptors, Uas tau siv los kho ntau yam kev neurological thiab kev puas hlwb.
- Kev Loj Hlob Hormone zais zais zais cia, uas txhawb qhov kev tso tawm ntawm kev loj hlob tuaj ntawm lub qog pituitary.
- Cov tshuaj muaj plawv, uas hom phiaj ntau yam ntawm kev tiv thaiv kev tiv thaiv kab mob plawv thiab kab mob.
- Notropic cov tshuaj tiv thaiv (ntse tshuaj), uas txhim kho kev txawj ntse thiab kev nco.
- Anti {- Cov tshuaj ua npaws, uas cuam tshuam cov kab mob npaws cuam tshuam tus kab mob.
- Cov tshuaj rau cov kab mob pob txha, xws li cov uas txhawb cov pob txha kev loj hlob lossis txwv tsis pub cov pob txha rov qab.
- Muab nws cov kev siv dav dav, nws txuas ntxiv mus nyiam cov kws tshawb fawb hauv kev lag luam kws tshuaj. Kev tshawb nrhiav txuas ntxiv yuav tshem tawm cov kev siv ntxiv kev siv rau cov ntsiab lus no lossis nws cov derivatives.
Yuav ua li cas kom cov kev hloov kho ntawm cov tebchaw uas twb muaj lawm
1. Nkag siab txog cov qauv sib xyaw thiab cov khoom
- Kev Ntsuas Cov Qauv: Pib nkag siab cov qauv molecular ntawm lub hom phiaj sib txuas, suav nrog nws pawg ua haujlwm, piv txwv li kev sib raug zoo (piv txwv li, hydrogen tsev, ionic sib khi).
- Kev soj ntsuam cov cuab yeej: Txheeb xyuas cov khoom siv lub cev thiab tshuaj lom neeg ntawm cov compound, xws li melting taw tes, solubility, solubility, stability, thiab roj ntsha, thiab roj ntsha.
2. Txhais lub hom phiaj
- Lub hom phiaj kom meej meej lub hom phiaj ntawm kev hloov kho, txawm hais tias nws yog txhawm rau txhim kho cov cuab yeej tshwj xeeb, hloov cov txheej txheem ntawm kev ua, lossis tsim daim ntawv thov tshiab.
3. Txheeb xyuas cov tswv yim txhim kho
- Cov qauv kev ua haujlwm: Hloov cov pab pawg ua haujlwm los ntawm kev hloov chaw, ntxiv rau, lossis kev tshem tawm cov kev tawm tsam. Qhov no suav nrog kev hloov pauv ntawm polarity, hydrophobicity, lossis reactivity ntawm cov molecule.
- Yog dab neeg: Tshawb nrhiav cov qauv sib txawv ntawm cov ntawv sib txuas ntawm cov compound kom pom yog tias lawv pom cov khoom xav tau.
- Polymerization lossis oligomerization: Ua ke ntau cov koog ntawm cov compound los ua cov polymers lossis oligomers, hloov nws lub xeev thiab cov khoom.
- Ntsev Kev Tsim: Daim ntawv sau cov kua qaub nrog cov kua qaub lossis hauv paus txhawm rau txhim kho solubility lossis ruaj khov.
- Nyuaj: Daim ntawv sib xyaw nrog hlau ions lossis lwm yam liigands los hloov cov compound cov khoom.
- Chairality Tswj: Kho lub Subteochemistry kom muaj kev cuam tshuam txog kev muaj roj ntsha lossis kev pheej hmoo.
4. Tsim thiab npaj cov txheej txheem hloov kho
- Txoj Kev Soj Ntsuam: Tsim cov ncauj lus ntxaws ntxaws uas qhia txog cov kauj ruam tsim nyog kom ua tiav qhov kev hloov kho uas xav tau.
- Reagent xaiv: Xaiv cov tshuaj reagents tsim nyog thiab catalysts uas tau sib txuas nrog lub hom phiaj sib txuas thiab cov kev xav tau hloov tshiab.
- Cov xwm txheej ua kom zoo: Kev sim nrog cov tshuaj tiv thaiv kab mob (piv txwv li, kub, siab, muaj kuab tshuaj) kom pom kev zoo, thiab ua haujlwm.
5. Ua kom hloov kho
- Ua cov synthesis nyob ib puag ncig tswj, raws li tsim kev nyab xeeb kev nyab xeeb kev nyab xeeb.
- Saib xyuas cov tshuaj tiv thaiv kev nce qib siv cov txuj ci kev ntsuas xws li TLC, HPLC, NMR, lossis MS.
6. Cov xeeb ceem thiab kev tshuaj xyuas
- Cwj pwm hloov kho cov compound siv ntau txoj kev tshawb nrhiav kom paub meej tias nws cov qauv thiab kev coj dawb huv.
- Txheeb xyuas nws cov khoom thiab kev ua tau zoo piv rau cov ntawv sib txuas qub.
- Kev ua raws roj ntsha lossis ua haujlwm tau yog tias muaj peev xwm ntsuam xyuas cov txiaj ntsig xav tau.
Qhov kev tshawb pom thiab kev loj hlob ntawmN - boc-3-carboetoxy-4-piperidone, muaj ntau cov organic sib xyaw, muaj cov chaw nres tsheb tseem ceeb hauv cov duab tshuaj chemistry, hluavtaws cov organic orgistry, thiab cov khoom siv tshuaj ntsuam. Keeb kwm los ntawm kev nrhiav cov scaffolds tshiab rau kev tsim tshuaj, qhov no tau paub txog lawv cov kev kawm ntau yam thiab muaj peev xwm ua si.
BOC (tert - butoxycarbonyl) tiv thaiv pawg tau qhia meej thiab tso cai rau kev ua haujlwm ntxiv yam tsis muaj kev sib cuam tshuam cov qauv tseem ceeb. Qhov sib ntxiv ntawm carboetoxy moiental ntawm 3-txoj hauj lwm tsis tsuas yog nce cov molecular plhuav tab sis tseem qhia cov chaw muaj tshuaj lom zem ntxiv lossis kev sib txuam.
Kev tshawb fawb tshawb fawb nyob ib puag ncig nws tau muaj ntau yam multifaceted. Ib qho tseem ceeb tau tshawb xyuas nws lub peev xwm los ua lub tsev sib tsoo hauv cov synthesatis ntawm bioaction molecules lossis enzymes koom nrog cov txheej txheem kab mob. Cov kws tshawb fawb kuj tseem tab tom tshawb xyuas nws siv ua ib nrab nyob rau hauv kev npaj ntawm ntau dua heterocyclic tshuab heterocyclicies, uas feem ntau nthuav qhia cov khoom ntiag tug thiab kev siv.
Ntxiv mus, nrog kev txaus siab loj hlob hauv Green Chemistry thiab cov kws tshawb nrhiav tau tshawb nrhiav cov kev kawm ib puag ncig rau kev npaj thiab nws cov derivatives. Qhov no suav nrog kev txhim kho cov tshuab catalytic uas txhawb nqa high loo nrog cov khib nyiab tsawg.
Hauv kev xaus, qhov kev tshawb pom thiab kev txhim kho txuas ntxiv ntawmN - boc-3-carboetoxy-4-piperidoneSawv cev rau txoj kev nce qib tseem ceeb hauv thaj chaw Organic synthesis, qhib tshiab txoj kev tshiab rau tshuaj nrhiav pom, cov ntaub ntawv kev tsim kho, thiab cov txheej txheem kev txhim kho.
Raws li cov organic sib xyaw, qhov ruaj khov ntawm n - boc {4 4}} 3-piperidone yog feem ntau cuam tshuam los ntawm nws cov qauv tshuaj. Cov compound no yuav muaj cov pab pawg ua haujlwm, xws li amino (tiv thaiv los ntawm n-boc), carbonyl, thiab cov pab pawg neeg estr. Cov kev ua ntawm cov pab pawg ua haujlwm hauv pab pawg tau txiav txim siab txog qhov ruaj ntseg tag nrho ntawm cov compound.
N {- boc tiv thaiv pawg yog ib feem ntau siv amino tiv thaiv pawg uas tuaj yeem tiv thaiv cov pab pawg neeg uas tsis ruaj khov los ntawm kev ua cov pa roj carbon nitrogen ruaj khov. Cov pab pawg tiv thaiv no tuaj yeem nyob tsis ruaj khov nyob rau hauv acidic los yog alkaline tej yam kev mob thiab tsis muaj feem rau hydrolysis lossis tsis muaj kev cuam tshuam. Yog li ntawd, n {- Boc feem hauv cov tshuaj pab kom nce qhov ruaj khov ntawm txhua qhov sib xyaw.
Meanwhile, cov EthoxycarbonyL pab pawg (piv txwv li ethyl ester pab pawg) kuj yog ib pab neeg ua haujlwm ruaj ntseg. Nyob rau hauv ib txwm ib txwm muaj tej yam kev mob cia, angyl ester pab tsis yooj yim hydrolyzed, yog li tswj hwm cov txheej txheem txheej txheem tag nrho ntawm cov compound.
Cia cov neeg muaj kev cia thiab ruaj khov
Yuav kom muaj kev ruaj khov, nws yog qhov tsim nyog los xaiv cov neeg tuaj yeem tsim nyog. Feem ntau hais lus, khaws cia cov organic sib txuas ua ke hauv qhov chaw qhuav, txias, thiab chaw tsaus tuaj yeem txuas ntxiv lawv lub txee ua kom ntev. Rau nws, cov cai cia hauv qab no yuav pab tswj hwm nws cov khoom ruaj khov:
Kub:
Khaws cov tebchaw ntawm qis dua kub tuaj yeem qeeb lawv cov decomposition. Nws feem ntau pom zoo kom khaws cov organic sib txuas hauv tub yees lossis lub freezer kom tswj lawv txoj kev ruaj khov.
Vaum noo:
Khaws cia ib puag ncig qhuav tuaj yeem tiv thaiv cov kev cuam tshuam hydrolysis ntawm cov tebchaw. Yog li ntawd, nws yog ib qho tsim nyog yuav kom ntseeg tau tias lub thawv ntim khoom tau kaw zoo thiab tsis txhob muaj kev sib cuag nrog huab cua noo.
Lub Teeb Raug:
Zam kev ntev ua rau lub teeb muaj zog, raws li nws yuav ua rau qee cov tshuaj tiv thaiv kev lom zem uas ua rau muaj kev txiav txim siab sib xyaw.
Tshuaj Ntsuam Xyuas Kev Ntsuas Xyuas Kev Ntsuas Xyuas
Kom nkag siab txog nws cov ruaj khov nyob rau hauv cov kev ntsuas sib txawv, kev ntsuam xyuas tshuaj lom neeg muaj peev xwm ua tau. Cov kev xeem no yuav suav nrog:
Kev Ntsuas Hluav Taws Xob Hluav Taws Xob Hluav Taws Xob:
Ua kom sov lub compound ntawm ntau kub rau ib lub sijhawm, thiab tom qab ntawd sim nws cov kev lom zem. Qhov no pab txiav txim siab cov thermal decomposition kub thiab thermal ruaj ntawm lub compound.
Hydrolysis Ruaj Khwv:
Tso cov kev daws teeb meem ntawm cov pH qhov tseem ceeb ntawm pH qhov tseem ceeb thiab saib nws covydrolysis tus nqi thiab cov khoom siv hydrocysis. Qhov no yuav pab kom nkag siab txog qhov muaj kev ruaj ntseg ntawm cov sib txuas hauv cov kua qaub sib txawv - puag mob.
Kev Ntsuam Xyuas Kev Ruaj Ntseg:
Nthuav tawm cov compound kom muaj zog lub teeb rau ib lub sijhawm thiab tom qab ntawd sim nws cov kev lom zem. Qhov no pab txiav txim siab qhov rhiab ntawm cov tebchaw rau lub teeb.
Cim npe nrov: n - boc-3-carboetoxy-4-piperidone CAS 98977-34-5, chaw tsim khoom, chaw tsim khoom, yuav khoom, rau muag