Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam thiab cov chaw muag khoom ntawm triethyl 2-phosphonopropionate CAS6696-9 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale ntau cov khoom lag luam zoo nkauj 2-phosphonopropionate CAS6699-66-9 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Triethyl 2-phosphonopropionateYog cov tshuaj sib xyaw ua ke nrog cov chav kawm ntawm Egorgophophorus teb. Nws muaj cov tshuaj c9h21o3p, hnyav hnyav ntawm 212.23 g / mol. Qhov tsis muaj kob no rau cov kua daj me ntsis
Kev tsim qauv, cov khoom muaj cov tsiaj tom ntej ntawm 2-txoj hauj lwm nrog phosphonate (po3) pawg. Cov pab pawg phosphonate yog ntxiv esterified nrog peb ethyl (C2h5) pawg. Qhov kev teeb tsa no tso cai rau ntau yam kev pheej hmoo ua, ua rau nws muaj txiaj ntsig zoo hauv cov khoom siv tshuaj.
Qhov sib xyaw ua ke yog qhov ruaj khov nyob rau hauv ib txwm muaj mob tab sis tuaj yeem yauv mus rau cov dej cawv thiab phosphonic acids sib piv thiab phosphonic acids sib piv. Nws yog soluble hauv cov kuab tshuaj muaj kuab tshuaj xws li ether, esters, thiab ketones, tab sis tsawg dua kom dej.
Vim nws cov qauv tshwj xeeb, nws pom cov ntawv thov hauv ntau thaj teb. Hauv kev ua liaj ua teb, nws ua haujlwm ua ntej ua ntej rau cov xwm txheej ntawm qee yam tshuaj tua kab thiab cov tshuaj tua kab, siv nws cov haujlwm. Hauv kev lag luam kws tshuaj, nws tau ua haujlwm ua lub tsev thaiv kev npaj rau cov tshuaj kis cov kev sib tw biochemical tshwj xeeb. Ib qho ntxiv, nws lub luag haujlwm hauv cov ntaub ntawv kev tshawb fawb, tshwj xeeb tshaj yog nyob rau hauv synthesis ntawm cov nplaim hluavtaws thiab polymer additives, underscores nws qhov tseem ceeb tshaj plaws.
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Tshuaj Cov Qauv |
C9H19O5P |
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Muaj pes tsawg leej |
238.10 |
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Molecular hnyav |
238.22 |
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m/z |
238.10 (100.0%), 239.10 (9.7%), 240.10 (1.0%) |
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Kev Ntsuam Xyuas |
C, 45.38; H, 8.04; O, 33.58; P, 13.00 |
Wittig -} horner reagent
Nws ua haujlwm ua tus tseem ceeb reagent nyob rau hauv lub wittig - horner cov tshuaj tiv thaiv, uas yog ib qho kev hloov kho thiab siv tau dav.
Lub wittig -} Horner cov kev tawm tsam tau tshwj xeeb tshaj plaws nyob rau hauv synthesis ntawm acrylic acid thiab nws cov derivatives thiab nws derivatives. Cov tshuaj tiv thaiv no cuam tshuam nrog cov hws ntawm aldehydes lossis ketones nrog phosphorus -}} muaj reagent, xws liTriethyl 2-phosphonopropionate, raws li cov xwm txheej tshwj xeeb. Cov tshuaj tiv thaiv feem ntau los ntawm kev tsim ntawm ib nrab, uas tom qab ntawd tau tshem tawm tshem tawm cov khoom lag luam olefinic, hauv qhov no, acrylic acid lossis cov khoom sib xyaw.
Cov versatility ntawm wittig - horner cov kev tawm tsam hauv nws lub peev xwm los hloov ntau yam ntawm cov acrylic acids lossis Olefins. Qhov no ua rau nws muaj txiaj ntsig zoo hauv cov khoom siv hluav taws xob hauv cev, tshwj xeeb tshaj yog rau kev npaj ntawm cov tebchaw nrog cov pab pawg ua haujlwm thiab cov nyiaj txiag sib luag.
Hauv cov ntsiab lus, nws lub luag haujlwm ua tus neeg tseem ceeb hauv cov khoom siv acrylic thiab muaj feem xyuam nrog cov} acid acid thiab sib xyaw ua ke ntawm cov organic molecules uas tuaj yeem tsim los ntawm cov tshuaj tiv thaiv no.
Hais txog wittig -} Horner Cov tshuaj tiv thaiv
Lub wittig -} Horner cov tshuaj tiv thaiv yog qhov sib txawv ntawm cov tshuaj tiv thaiv zoo nkauj wittig, siv feem ntau rau cov synthesis ntawm alkenes. Nws ua haujlwm phosphonates, tshwj xeeb - phosphonates tsis txhob siv cov tshuaj phosphonium ylides siv tau hauv cov tshuaj lom neeg. Kev siv phosphonates muaj ob peb qhov zoo, suav nrog kev npaj tau yooj yim thiab tuav, nrog rau cov qoob loo ntau dua thiab cov cim ntsuas hauv qee kis.
Phosphonate reagent yog ib txwm npaj ua ntej. Qhov reagent no muaj cov phosphorus atom uas cov pa, uas yog nyob rau hauv pab pawg neeg Alkyl lossis Aryl thiab Pawg Phosthech).
Nyob rau hauv lub hauv paus pib ntawm lub hauv paus (feem ntau sidium hydride, nah, lossis potassium tert {}- bookts nrog aldehyde lossis ketone. Lub hauv paus abstractracts ib cov qauv ntawm - Cov pa roj carbon ntawm phosphonate, sib sau ua lub npe tsis zoo, hu ua ylide.
Ylide yog qhov tseem ceeb hauv nruab nrab hauv cov tshuaj tiv thaiv no. Nws muaj tus nqi tsis zoo ntawm cov pa roj carbon atom uas yog Ameslikas nyob rau hauv phosphorus txuas rau hauv phosphorus, thiab tus cwj pwm zoo phosphorus atom.
Tus ylide ces undergoes ib qho kev tshem tawm infamolination, uas tus tsis zoo them cov tshuaj atom txawv atom tawm tsam carbonyl carbon ntawm aldehyde lossis ketone. Qhov no ua rau kev tsim cov carbon monoxide tshiab- cov pab pawg ib pawg ob npaug thiab cov cawv sib xws (los ntawm aldehyde lossis ketone). Xws liTriethyl 2-phosphonopropionateRov qab siv nrog formaldehyde, piv txwv li, kev tshem tawm ua rau kev tsim cov acrylic acid thiab triothyl phosphate li breproducts.
Tom qab cov tshuaj tiv thaiv tau ua tiav, cov tshuaj tiv thaiv sib xyaw yog feem ntau ua haujlwm cais tawm ntawm cais cov khoom olefinic. Qhov no tuaj yeem suav cov tshuaj tiv thaiv, rho tawm cov khoom lag luam, thiab ua kom huv los ntawm cov tswv yim xws li distillation lossis chromatography.
Tseem ceeb rau hauv synthesis
Cov mob me me
Nws tuaj yeem ua nyob rau hauv cov mob me me, uas tuaj yeem muaj txiaj ntsig zoo rau cua sov - rhiab substrates.
Lub ntsuas kev ua yeeb yam
Muaj qee kis, nws muaj ntau stereoselectivity piv rau cov tshuaj tiv thaiv classic.
Ua haum pab pawg pab pawg
Nws tiv taus ntau pab pawg ua haujlwm, tso cai rau cov cuab yeej ntawm cov lus qhia ntawm cov molecules.
Yooj yim ntawm kev npaj reagent
Phosphonates feem ntau yooj yim dua los npaj thiab lis ntau dua phosphonium ylides.
Cov ntawv thov nyob rau hauv synthesis ntawm acrylic acid thiab derivatives
Polymers
Lawv siv nyob rau hauv kev tsim cov noob polymers xws li polyacrylates, uas pom nyob rau hauv cov khoom lag luam zoo li cov xim tha xim, cov nplaum, thiab superabsorbents.
Surfactants
Acrylic acid derivatives tau siv nyob rau hauv kev tsim cov surfactants rau cov khoom lag luam thiab cov ntawv thov kev lag luam.
Crosslinking tus sawv cev
Lawv ua cov neeg sawv cev ntawm cov neeg sawv cev hauv ntau cov ntaub ntawv, txhim kho lawv cov khoom siv mechanical.
Los ntawm kev siv cov wittig -} Cov tshuaj tiv thaiv Hornerize, cov khoom siv hluav taws xob muaj txiaj ntsig zoo thiab ua rau kev txhim kho cov ntaub ntawv tshiab thiab thev naus laus zis.
Ib - pot chemoenzyfatic synthesis ntawm - butyrolactone:
- butyrolactone yog qhov nruab nrab tseem ceeb nyob rau hauv cov synthesis ntawm ntau yam tshuaj lom neeg thiab chaw muag tshuaj.Triethyl 2-phosphonopropionateYuav siv tau rau hauv ib qho - pot chemoenzyY cov txheej txheem rau synthesize- butyrolactone. Tus txheej txheem no ua ke cov tshuaj lom neeg thiab enzymatic, qhov twg cov phosphonate pab tau ua ntej lub nplhaib lactone rau kev tsim cov kev hloov pauv, suav nrog phosphoryLation, txo qis, thiab lactonization.
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Enantioselective synthesis ntawm spiroindanedicarboxylic acid los ntawm asymmetric hydrogenation:
Cov pab pawg phosphonate yog qhov tseem ceeb ntawm nws tuaj yeem cuam tshuam lub sereoselectivity ntawm tom ntej kev tawm tsam, tshwj xeeb li asymmetric hydrogenation.
Ua ntej rau Asymmetric hydrogenation, nws yuav yauv mus rau cov kev hloov pauv ntawm cov tshuaj lom neeg los sib xyaw cov Spampold thiab carboxylic acid kev ua haujlwm. Cov kev hloov pauv no tuaj yeem suav nrog kev ua ntshav, hws, thiab cov kev xav tau.
Rau asymmetric hydrogenation, ib chairal catalyst yog qhov tseem ceeb. Cov catalyst no tuaj yeem yog ib lub rhodium, ruthenium, lossis iridium complex ligated nrog chiral liigand, xws li diphosphine lossis suab nkauj ua hauj lwm. Phosphonate moiety txuas rau lub substrate tuaj yeem cuam tshuam nrog chairal catalyst, muaj peev xwm qhia lub sterosecective txo ntawm ovas lossis lwm qhov kev sib raug zoo uas tsis muaj tseeb nyob rau hauv cov ua ntej. Qhov kev sib cuam tshuam no pab kom ua tiav siab Enantioselectivity, nyiam qhov tsim ntawm ib qho enantiomer ntawm tus spiroindanedicCarboxylic acid dhau lwm.
Kev Lom Zem Intramolecular Diels -} Cov Neeg Sib Nraws:
Cov pab pawg phosphonate hauvTriethyl 2-phosphonopropionatetuaj yeem ruaj khov yog lub dienophile lossis cov chaw tiv thaiv ntawm cov tshuaj tiv thaiv. Lub zog no tshwm sim los ntawm cov teebmeem hluav taws xob, qhov chaw tsis zoo ntawm cov pa hluav taws xob muaj peev xwm cuam tshuam nrog cov pa hluav taws xob ntawm cov pa hluav taws xob ntawm ob tog.
Intramolecular cov tshuaj tiv thaiv tau muab kev tswj hwm zoo dua qub dua piv rau kev sib txuam, raws li cov reactants yog qhov ntsuas ntawm tes. Qhov sib thooj no txo cov neeg nkag mus ua tus nqi cuam tshuam nrog nqa cov reactants ua ke thiab tuaj yeem nyiam qhov tsim ntawm ib lub sijhawm. Lub peev xwm los ua rau - Cov tswv yim tswj hwm kev tsim kho ntawm cov txheej txheem molecular uas lub nplhaib tshiab tau sib xyaw ua ke rau hauv lub moj khaum molecular.
Muaj qee kis, cov tshuaj tiv thaiv tuaj yeem yog catalyzed los ntawm lewis acids, uas tuaj yeem txhim kho ntxiv los ntawm pab pawg phosphonate los ntawm pab pawg phosphonate no thiab modulating cov khoom hluav taws xob ntawm lub reacting moecties. Lub diels - Alder cov tshuaj tiv thaiv feem ntau ua rau cov mob me, ua rau nws muaj cov pab pawg ua haujlwm ntau.
Cov khoom lag luam
Trihothyl-2-phosphatopionate (CAS naj npawb 36-9) yog cov organic phosworth cov tshuaj tiv thaiv (xws li cov tshuaj tiv thaiv zoo nkauj, thiab lwm yam) thiab cov tshuaj lom neeg nruab nrab.
Kev tiv thaiv kab mob kom zoo
Qhov ncauj toxicity
Cov kev sim tsiaj tau qhia tias Triethyl 2-phospack refere muaj qhov ncauj muaj kev lom zem. Siv tsawg dua 150 grams tej zaum yuav ua rau tuag taus lossis ua rau muaj kev phom sij loj rau kev noj qab haus huv. Cov tshuaj lom me ntsis tuaj yeem cuam tshuam nrog cov txiaj ntsig organic ntawm acetylism, ntuav ua rau mob plab zom mov, ua rau mob plab zom mov, raws plab, mob plab zom mov, mob plab zom mov, ua pa, ua pa Ua tsis tiav, thiab txawm tias kev tuag.
Inhalation Toxicity
Nqus tau nws cov vapor lossis aerosol yuav ua rau mob ntsws, tshwj xeeb hauv lub hauv paus, hauv lub hauv paus tsis zoo yuav ua rau muaj kev pheej hmoo ua kom muaj kev pheej hmoo siab yog qhov pheej hmoo siab dua. Tam sim no, tsis muaj cov ntaub ntawv ntshiab ntawm kev ua kom tuag taus tib neeg, tab sis cov kev sim tsiaj tau pom tias nws cov tshuaj lom tau zoo nrog kev pom zoo thiab lub sijhawm raug.
Tawv thiab qhov muag
Daim tawv nqaij khaus: Kev tiv tauj ncaj qha yuav ua rau tawv nqaij liab, khaus, tawm pob, thiab txawm tias siv tshuaj hlawv. Lub sij hawm ntev los yog rov kis dua yuav ua rau kev hu rau Dermatitis, tus cwj pwm los ntawm qhuav, tawg, thiab tawv tawv.
Qhov muag khaus: Txaws mus rau hauv lub qhov muag yuav ua rau mob hnyav, ua rau mob muag, photophobia, conjunctival colgestion, thiab txawm tias castive puas tsuaj, thiab txawm tias castive puas tsuaj, thiab txawm tias castive puas tsuaj, thiab txawm tias castive puas tsuaj, thiab txawm tias castive puas tsuaj, thiab txawm tias castive puas tsuaj, thiab txawm tias correal puas tsuaj, thiab txawm tias correal puas tsuaj, thiab txawm tias casteal puas tsuaj, thiab txawm tias castive puas tsuaj, thiab txawm tias correal puas tsuaj. Yog tias tsis yaug lub sijhawm, yuav muaj cov teebmeem nyob rau xws li pom kev pom.
Mob ntev thiab ntev ntev kev pheej hmoo
Central Nervous System Inhibition
Lub sij hawm ntev los yog rov ua dua kis tau yuav ua rau nruab nrab ntawm cov hlab ntsha tsis sib xws, ua rau mob taub hau, kiv taub hau, nkees, thiab tsis muaj kev ntxhov siab. Muaj koob tshuaj muaj txiaj ntsig ntau yuav ua rau muaj kev ua txhaum, qaug, thiab tseem ua pa ua pa tuag tes tuag taw. Cov mechanism yuav cuam tshuam nrog kev cuam tshuam ntawm cov organic phosphorus teb rau ntawm cov kab ke neurotransmitter.
Ib puag ncig thiab ecological toxicity
Triethyl 2-phospackionate tej zaum yuav yog degraded nyob rau hauv ib puag ncig los ntawm cov khoom siv hydroline, thiab lwm yam kev ua pa, phosphorus oxides, thiab lwm yam). Yog tias tso tawm hauv cov khoom siv dej lossis av, nws yuav muaj cov tshuaj lom neeg lom neeg (xws li ntses thiab algae) thiab cov kab mob av, cuam tshuam nrog ecological tshuav nyiaj li cas.
Cim npe nrov: Trihoethyl 2-phosphonopnionate CAS699-66-9, cov chaw muag khoom, chaw tsim khoom, chaw tsim khoom, lag luam, yuav, nqi, loj, rau muag