Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov chaw muag khoom ntawm Deslorelin CAS 57773-65-6 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale mis zoo zoo deslorelin CAS 57773-65-65-6 Cia Muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Urrorelin, feem ntau yog nyob rau hauv daim ntawv ntawm kev cog lus, yog cov khoom siv khov kho uas yog xim dawb lossis me ntsis daj rau hauv cov xim. Nws cov duab yuav sib txawv raws li cov chaw tsim khoom, tab sis Deslorin feem ntau yog cylindrical lossis pas nrig {1} zoo li tus txiv. Molecular Cov Qauv Molecular C64H83N17o12, CAS 57773 -}}}}}}} Lub solubility nyob rau hauv dej yog tsawg vim tias nws yog tsim rau kev tso tawm qeeb kom tsis tu ncua tawm cov tshuaj nyob hauv cov tsiaj lub cev, yog li tswj hwm cov kev xav tau zoo. Kuj tseem nyob ruaj khov nyob rau hauv chav tsev kub, tab sis yuav tsum tau muab cia kom deb ntawm lub teeb kom tiv thaiv kev siv yeeb tshuaj. Ib qho ntxiv, raws li nws yog tsim rau kev cog lus hauv cov tsiaj, nws feem ntau muaj qhov zoo tsis kam mus rau biodegradoration. Raws li kev cog lus, deserellin xav tau ib qho kev siv zog ib yam kom nws yuav tsis tawg lossis yaj thaum cog ntawm cov tsiaj. Nws yuav tsum muaj qee qib ntawm hardness thiab kev nruj heev los tiv thaiv kev ntxhov siab thaum lub sijhawm cog lus. Mas siv rau kev sib deev tswj cov tsiaj, tshwj xeeb yog nees. Nws yog dav siv nyob rau hauv cov kws kho tsiaj teb kom inhibit tsiaj es ovulation los yog inhibiting lub zais ntawm gonadotropins.
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Customized raj yas thiab corks:
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Tshuaj Cov Qauv |
C64H83N17O12 |
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Muaj pes tsawg leej |
1282 |
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Molecular hnyav |
1282 |
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m/z |
1282 (100.0%), 1283 (69.2%), 1284 (23.6%), 1283 (6.3%), 1285 (5.3%), 1284 (4.3%), 1284 (2.5%), 1285 (1.7%), 1285 (1.4%) |
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Kev Ntsuam Xyuas |
C, 59.94; H, 6.52; N, 18.57; O, 14.97 |
Urrorelin, tseem hu ua Deshloreli Acetate, yog qhov hluavtaws Gonadotropin- tso cov ntawv Hormon (GNRH) tus lej ntawm 57773-65-6. Raws li peptide tshuaj, nws ua kom lub Gnrh receptor piduitary caj pas, lh) thiab follicle stimulating Hormon (FSH). Tom qab, vim muaj kev ntsuas cov tshuaj ntsuam xyuas, cov qib cov tshuaj hauv cov ntawv hauv cov tshuaj hauv downregulated, thaum kawg inhibiting steroid safties thiab kev sim.
1. Mare Kev tswj hwm
Nws yog cov tshuaj tseem ceeb hauv cov txheej txheem dag ntawm tus poj niam. Los ntawm txhaj deserelin, lub sij hawm ovulation ntawm mare tuaj yeem raug tswj hwm yog, txhim kho cov fertility tus nqi. Nws cov tshuab kev ua yog los txhawb LH Pripion Peak hauv theem pib, txhawb nqa follicle kom tiav thiab ovulation; Nruam kev tswj hwm inhibits lH thiab fsh zais cia, zam kev tsis xav ovulation. Piv txwv li, kev pom zoo ua ntej, tau pom zoo los ntawm Asmeskas FDA, tau siv dav dav siv hauv Nees sib tw ua kev sib tw, ua kom luv luv.
2. Ruaj khov siab - cev xeeb tub
Hauv kev ua tsiaj ua tsiaj xws li nyuj thiab yaj, nws tuaj yeem siv los tswj cov siab siab {}} kev pheej hmoo cev xeeb tub. Los ntawm kev tswj hwm cov lus Hormon, kev pheej hmoo ntawm kev nchuav menyuam tuaj yeem raug txo kom tsawg. Kev tshawb fawb tau pom tias siv deserelin rau poj niam tsiaj nrog keeb kwm ntawm kev nchuav menyuam yaus nce qib kev xeeb tub los ntawm kwv yees li 20%.
3. Lwm txoj kev xaiv rau tus khub tsiaj kom tsis muaj menyuam
Deserelin kev cog lus (xws li supelorin) muab ib qho tsis -} kev phais rau cov dev thiab ferrets. Cov cog hniav maj mam tso tawm cov tshuaj, txuas ntxiv cov neeg tsis tu ncua hormon zais cia, thiab ua tiav kev siv tshuaj lom kom tsis muaj kuab lom. Nws tau txais txiaj ntsig zoo nyob rau hauv reversibility: Tom qab txuas ntxiv, kev ua me nyuam muaj peev xwm rov qab los, ua kom haum rau tsiaj uas yuav tsum tau khaws lawv cov muaj peev xwm.
4. Kev kho mob ntawm Canine prostate hyperplasia
Los ntawm inhibiting Testosterone zais pa ntawm cov dev nrog benign prostatic hyperplasia (bpp) tuaj yeem txo qis, thiab kev tso zis tuaj yeem cuam tshuam. Cov ntaub ntawv kuaj mob qhia tau tias tom qab 3 lub hlis ntawm kev kho mob, lub postate ntim txo qis los ntawm qhov nruab nrab ntawm 35% thiab cov tsos mob txhim kho ntau.
1. Prostate cancer tshuaj
Deserelin, raws li GNRH agonist, block txoj kev loj hlob ntawm cov mob hlwb los ntawm kev ntsuas testosterone txuas ntxiv. Nws ntev {{- Kev txhaj tshuaj (xws li kev txhaj tshuaj txhua lub hlis) tuaj yeem txo cov neeg mob 'serum seriesosterone keeb kwm. Txawm hais tias tam sim no tsuas yog siv nyob rau hauv cov tsiaj, theem i i i i i i i i i i i i i i idical sim hais tias nws qhov kev ua tau zoo rau kev phais mob, thiab nws cov kev mob tshwm sim feem ntau.
2. Envometrisosis thiab Uterine Fibroids
Los ntawm kev tiv thaiv hluav taws xob estrogen zais, muab cov tsos mob mob ntawm endometriosis thiab txo lub ntim ntawm uterine fibroids. Hauv kev sim sim, cov neeg mob cov qhab nia mob kom tsawg dua li 50%, thiab cov ntim ntawm fibroids txo li 40%.
Txawm li cas los xij, ntev {{-}} ext} osteoporosis, thiab tam sim no siv tau cov kev kho mob ua ntej lossis luv}}}}}
3. Kev cuam tshuam rau kev tshaj tawm txoj kev kawm tiav nraug
Nws tuaj yeem siv los kho cov kev ua kom haum rau kev ua kom zoo nkauj tiav nraug los ntawm kev sib deev ntawm poj niam txiv neej hormons, thiab ncua kev vam meej. Kev tshawb fawb qhia tau hais tias tom qab kev kho mob tom qab kev kho mob, cov menyuam yaus tau kwv yees kom lawv qhov siab loj los ntawm 3-5 tus neeg laus.
4. Polycystic Ovary Syndrome (PCOS) Kev Tswj Xyuas
Los ntawm kev tswj hwm LH zais cia, kho hyperandrogenism hauv PCOs cov neeg mob thiab rov qab kho cov ovuring kev voj voog. Cov ntsuas hluav taws xob me tau pom tias cov ovuration rov ua dua tus nqi tuaj yeem ncav cuag 70% thaum ua ke nrog lwm cov tshuaj.
1. Kev tshawb fawb me nyuam biology
Raws li ib tug tshwj xeeb agonist ntawm GNRH receptor,Urrorelinyog dav siv los kawm cov txheej txheem kev cai ntawm hypothalamic partuitary gonadal axis. Piv txwv li, los ntawm Deserelin kev sim ua, kev zais cia kinetics ntawm LH thiab FSH tau ntsuas, muab cov cuab yeej rau kev ua me nyuam kab mob endocrine cov qauv.
2. Cov Qauv Kev Tsim Tshuaj
Thiab nws cov analogues (xws li Goserelin) tau siv ua qauv rau kev ua si sib piv thiab tswj hwm zoo hauv kev txhim kho kev siv tshuaj tshiab. Nws qhov siab {- Kev Pauv Txoj Kev Pauv
3. Kev tshawb fawb ntawm tus cwj pwm tsiaj
Nyob rau hauv tsis {{0} human kev tshawb fawb, nws yog siv los tshawb txog kev sib deev hormons ntawm kev coj ua tus cwj pwm, kev ua phem, thiab lwm yam. Piv txwv, kev tshawb fawb ntawm Pob Zeb Hyrax tau pom tias qhov cog ntawm cov neeg coj cwj pwm, muab cov nqi rau kev nkag siab ntawm tib neeg tus cwj pwm.
Enzymatic synthesis yog ib txoj kev ntawm synthesizing lub hom phiaj sib txuas siv cov enzymes li catalysts. Nyob rau hauv tus txheej txheem ntawm enzymatic synthesis ntawm desloreli, muaj cov enzymes tshwj xeeb yog siv los ua kom pom cov tshuaj tiv thaiv cov tshuaj lom neeg, yog li nthuav tawm Deserellin hauv kev ua tau zoo, tshwj xeeb, thiab tswj tau. Txawm hais tias cov kev sib txuam tshwj xeeb enzymatic yuav sib txawv raws li kev tshawb fawb thiab kev txhim kho ntawm cov kauj ruam thiab tshuaj sib txig sib luag rau enzymatic synthes ntawm deserellin.
- Cov kauj ruam rau Enzymatic synthesis ntawm deserellin
Kev npaj ntawm cov khoom pib: ua ntej, nws yog qhov tsim nyog los npaj pib cov khoom haum rau enzymatic cov tshuaj tiv thaiv. Cov ntaub ntawv raw feem ntau muaj cov pab pawg ua haujlwm tau lees paub uas tuaj yeem lees paub los ntawm cov enzymes thiab ua rau muaj kev hloov dua siab tshiab.
Xaiv cov enzymes uas tsim nyog uas tsim nyog ntawm cov qauv txheej txheem ntawm cov khoom pib thiab hom phiaj compound, xaiv cov enzymes uas tuaj yeem ua kom cov tshuaj tiv thaiv cov tshuaj uas xav tau. Cov enzymes no yuav yog ntuj los yog hloov los ntawm caj ces lossis protein engineering.
Enzyymatic xav: Raws li qhov tsim nyog cov kev tshwm sim (xws li qhov ntsuas kub, pawj qab, cov khoom siv enzyme tau sib xyaw ua ke los pib ua kom haum. Cov enzymes txo qhov kev ua kom muaj zog ntawm kev tawm tsam los ntawm kev siv cov tshuaj tiv thaiv, yog li ua kom muaj kev nrawm nrawm ntawm cov tshuaj tiv thaiv.
Tsim ntawm intermediates: nyob rau hauv kev txiav txim ntawm enzymes, pib cov khoom undergoes rau cov kev hloov pauv ntawm cov kev sib xyaw ua ke. Cov intermediates no yuav yog ib lossis ntau dua, nyob ntawm cov kev tawm tsam ntawm txoj kev tiv thaiv thiab enzyme catalytic me ntsis.
Ntxiv hloov dua siab tshiab ntawm cov nruab nrab: Cov intered intermediates txuas ntxiv mus rau kev txiav txim ntawm cov enzymes, maj mam nce cov qauv ntawm lub hom phiaj sib txuas.
Ntau tiam ntawm cov phiaj sib txuas: tom qab muaj cov tshuaj tiv thaiv enzymatic, deserellin thaum kawg tsim tawm. Txij ntawm no, kev sib cais kom tsim nyog thiab cov tswv yim ua kom muaj zog xav tau los cais cov phiaj sib xyaw los ntawm cov tshuaj tiv thaiv kab mob.
Tus qauv cim ntawm cov khoom lag luam: Siv spectroscopic, chromatographic thiab lwm txoj kev los txheeb xyuas tus qauv ntawm cov tsim tawm, kom ntseeg tau tias nws cov qauv sib ntsib.
- Kev Mob Tshuaj
Piv txwv li, yog tias synthesis ntawmUrrorelinPib los ntawm compound a, undergoes catalytic hloov dua siab tshiab los ntawm enzyme E1 rau intermediate catalytic hloov dua tshiab los ntawm enzyme E2 rau interpediate citectedict los ntawm enzyme E2 rau interates deserellin d, tom qab ntawd cov txheej txheem no tuaj yeem hais tawm raws li:
A+E1 → B
B+E2 → C
C → D
Cov xub ntawm no qhia cov kev taw qhia ntawm cov tshuaj tiv thaiv enzinatic, thaum E1 thiab E2 sawv cev cov enzymes koom nrog cov tshuaj tiv thaiv. Qhov tseeb tshaj lij sab nrauv txoj kev yuav nyuaj, muaj kev cuam tshuam nrog cov kauj ruam thiab cov kauj ruam ntxiv.
Cim npe nrov: Deslorelin Cas 57773-65-6, Cov chaw muag khoom, chaw tsim khoom, Hoobkas, lag luam Wholesale, yuav, nqe, loj, loj, rau muag