Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm melanotan 2 hmoov cas 121062-08-6 nyob Suav teb. Txais tos rau cov lag luam wholesale bulk zoo melanotan 2 hmoov cas 121062-08-6 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Melanotan 2 hmoovyog ib tug hluavtaws melanocortin receptor agonist. Nws yog ib qho tshuaj txhaj tshuaj polypeptide uas txhawb nqa tanning. Melanotan, CAS 121062-08-6, feem ntau yog cov hmoov dawb dawb. Qhov hnyav molecular yuav cuam tshuam nrog nws cov amino acid ib ntus thiab qib ntawm cyclization. Feem ntau hais lus, qhov hnyav molecular ntawm peptides nyob ntawm ntau txhiab mus rau kaum txhiab. Nws muaj dej solubility zoo thiab muaj roj solubility. Thaum lub sij hawm txheej txheem synthesis, cov kuab tshuaj xws li N, N-dimethylformamide (DMF), pyridine, tetrahydrofuran (THF), thiab ether yuav tsum tau siv rau cov tshuaj tiv thaiv. Nws yog ib qho hluavtaws melanocortin receptor agonist. Nws yog ib qho tshuaj peptide hormone uas tuaj yeem txhawb nqa tanning. Peb muaj melanotan ii peptide muag. Yog tias koj xav yuav melanotan ii online, thov hu rau peb tus neeg muag khoom.
Peb muab ib qho piv txwv ua lag luam ntawm no:
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Lub cev & tshuaj muaj zog
Solubility
H2O: 5 mg/mL, soluble. Kuj tseem muaj methanol thiab ethyl acetate, tab sis nws cov solubility tsis zoo nyob rau hauv uas tsis yog -polar solvents
Acidity coefficient (pKa)
13.00 ± 0.70 (Tshaj tawm)
Kev ruaj ntseg
Nws yog qhov ruaj khov ntawm chav tsev kub, tab sis yuav decompose nyob rau hauv qhov kub thiab txias, lub teeb, acid thiab alkaline tej yam kev mob
Dej solubility
Soluble rau 0.70 mg / ml hauv dej
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Melanotan II COA
01.Lub sij hawm xa tuaj rau teb chaws Poland ntev npaum li cas?
02.Yog them nyiaj ua ntej?
- meej cov ntaub ntawv khoom, specifications thiab qty
- lus hais
- them
- nkoj
- tom qab kev pabcuam
03.Nws puas tuaj yeem tsim GHK CU tab sis ntawm ib koob ntawm 20 mg / vial? Bpc 10 mg? Nws puas tuaj yeem hloov pauv tus nqi ntawm cov khoom?
04.Kuv xav nug cov duab ntawm cov khoom, cov vials koj tsim zoo li cas?
05.Ntawm qhov ntau npaum li cas kuv tuaj yeem suav cov nyiaj cheb?
Melanotan II, tseem hu ua MT-II, yog ib qho hluavtaws peptide hormone analog uas tau txais kev nyiam nyob rau xyoo tas los no rau nws cov kev siv tau hauv daim tawv nqaij tanning thiab kev sib deev. Cov peptide no txhawb kev tsim cov melanin, cov xim uas muab cov xim ntawm cov tawv nqaij, ua rau cov tsos tsaus dua, bronzed dua.
Ib qho ntawm cov kev siv tseem ceeb ntawm Melanotan II yog nyob rau hauv kev kho kom zoo nkauj. Ntau tus neeg nrhiav kom ua tiav qhov tob dua, ntuj tsim dua - saib tan tsis tas yuav raug tshav ntuj ntau dhau lossis siv cov khoom siv dag zog. Melanotan II tuaj yeem pab ua tiav qhov no los ntawm kev txhawb nqa melanin ntau lawm hauv daim tawv nqaij, tso cai rau cov neeg siv los tsim cov tawv nqaij uas tsis tshua raug UV rays.
Ntxiv rau nws cov kev siv tshuaj pleev ib ce, Melanotan II kuj tau tshawb fawb txog qhov muaj peev xwm ua kom muaj kev sib deev. Qee qhov kev tshawb fawb tau qhia tias peptide yuav muaj kev cuam tshuam rau libido thiab kev sib deev arousal. Txawm li cas los xij, nws tseem ceeb heev uas yuav tsum nco ntsoov tias cov kev cuam tshuam no tsis nkag siab lossis dav lees paub, thiab xav tau kev tshawb fawb ntxiv kom paub meej tias muaj txiaj ntsig kev sib deev.
Melanotan 2 hmoovtshawb fawb los ntawm: BLOOM TECH
Lus Cim: BLOOM TECH (Txij li xyoo 2008), ACHIEVE CHEM-TECH yog lub chaw pabcuam ntawm peb.
Melanotan 2 hmoov, tseem hu ua - Melanocyte stimulating hormone yog endogenous peptide nrog lub zog melanocyte stimulating hormone ua haujlwm. Raws li ib txwm muaj lub cev muaj zog, nws tsuas yog tswj cov hypothalamic pituitary adrenal axis, khi rau thiab ua kom cov melanocyte stimulating hormone receptor subtype MC1R, ua rau melanocytes tsim melanin. Txawm li cas los xij, yog tias siv cov txheej txheem hauv kev sim tshuaj los npaj Melanotan manually, cov kauj ruam hauv qab no yuav tsum tau:
Kev npaj khoom siv
Amino acids
Cov amino acids uas yuav tsum tau rau synthesizing Melanotan muaj xws li tryptophan, histidine, lysine, methionine, leucine - Aminobutyric acid, aspartic acid, phenylalanine, serine, arginine, proline, valine, isoleucine, alanine, thiab glycine. Cov amino acids no yuav tsum tau muab rau hauv cov hmoov los yog crystalline thiab purified ua ntej synthesis.
Solvent
Lub synthesis ntawm Melanotan yuav tsum tau siv cov kuab tshuaj xws li N, N-dimethylformamide (DMF), pyridine, tetrahydrofuran (THF), thiab ether.
Reagents
Lub synthesis ntawm Melanotan kuj xav tau qee cov tshuaj reagents, xws li sodium hydroxide, sodium hydride hydrochloride, lithium aluminium hydride hydrochloride, ethylene glycol, thiab lwm yam.
Khoom theem peptide synthesizer
Qhov ntsuas no tuaj yeem ua tiav cov txheej txheem peptide synthesis, suav nrog cov kauj ruam xws li amino acid condensation, deprotection, thiab tu.
Synthesis cov kauj ruam
Ntxiv cov amino acids uas yuav tsum tau ua nyob rau hauv qhov kev txiav txim synthesis rau cov khoom -theem peptide synthesizer, thiab teem lub ntsuas kub rau 40℃. Tom qab ntawd ntxiv qhov tsim nyog ntawm diisopropylethyl chloromethane (DIPEA) thiab N, N-dimethylformamide (DMF) hnyav los pib cov tshuaj tiv thaiv condensation. Cov tshuaj tiv thaiv no yuav tsum tau nplawm thiab tiv thaiv nrog cov roj nitrogen.
Tom qab cov tshuaj tiv thaiv condensation tiav, yuav tsum muaj kev tiv thaiv kev tiv thaiv. Ntxiv qhov tsim nyog ntawm trifluoroacetic acid thiab dimethyl formamide (DMF) hnyav thiab txo qhov kub kom qis dua 0 degree. Tom qab ntawd ntxiv qhov tsim nyog ntawm sodium hydroxide aqueous tov kom tiav cov tshuaj tiv thaiv kev tiv thaiv.
Tom qab cov tshuaj tiv thaiv deprotection tiav lawm, yuav tsum muaj cov tshuaj tiv thaiv tu. Ntxiv ib qho dej uas tsim nyog rau kev ntxuav, thiab tom qab ntawd ntxiv cov ether tsim nyog rau kev ntxuav. Thaum kawg, ntxiv qhov tsim nyog ntawm pyridine rau ziab.
Tom qab kev ntxuav cov tshuaj tiv thaiv tiav, ntxiv cov amino acids uas yuav tsum tau ua hauv kev txiav txim rau lub raj mis cyclization. Ntxiv qhov tsim nyog ntawm N, N-dimethylformamide (DMF) hnyav thiab txo qhov kub kom qis dua 0℃. Tom qab ntawd ntxiv qhov tsim nyog ntawm lithium aluminium hydride hydrochloride thiab ethylene glycol tov kom tiav cov tshuaj tiv thaiv cyclization.
Tom qab cov tshuaj tiv thaiv cyclization tiav lawm, yuav tsum muaj cov tshuaj purification. Lim lub supernatant thiab ntxuav lub precipitate nrog ib tug tsim nyog tus nqi ntawm ether. Tom qab ntawd dissolve lub precipitate nyob rau hauv ib tug tsim nyog tus nqi ntawm cov dej thiab ntxiv ib tug tsim nyog tus nqi ntawm ion pauv kem rau purification kev kho mob. Thaum kawg, khov - ziab tau ua kom tau siab - purity Melanotan hmoov hmoov.
Cov saum toj no yog cov kauj ruam yooj yim rau synthesizing Melanotan. Cov tshuaj reagents thiab kev ua haujlwm koom nrog hauv cov kauj ruam no yuav tsum muaj kev tswj xyuas zoo thiab kev ntsuas kev nyab xeeb, uas yuav tsum tau ua nyob rau hauv cov chaw kuaj mob. Yog li ntawd, nws raug pom zoo kom ua cov kev sim synthesis hauv cov chaw tshawb fawb kev tshaj lij lossis cov chaw soj nstuam ntawm cov tuam txhab tshuaj.
Frontiers ntawm Neural Control
Neurocontrol yog cov txheej txheem uas lub paj hlwb tswj kev ua haujlwm ntawm lub cev ntawm lub cev los ntawm kev taw qhia cov molecules xws li neurotransmitters thiab cov tshuaj hormones.Melanotan 2 hmoov, raws li melanocortin receptor agonist, tuaj yeem khi rau ntau yam melanocortin receptors (MC receptors) thiab tswj kev ua haujlwm ntawm lub paj hlwb. Nyob rau hauv xyoo tas los no, nrog rau kev sib sib zog nqus ntawm kev tshawb fawb neuroscience, nws daim ntawv thov hauv kev tswj hwm neural tau maj mam nyiam. Nws cov haujlwm tshwj xeeb ntawm lub cev thiab cov txheej txheem dav dav ntawm kev ua haujlwm muab cov tswv yim tshiab rau kev tshawb fawb neuroscience thiab kev siv tshuaj kho mob.
Melanotan 2 tau pom tias muaj peev xwm thov tus nqi hauv thaj tsam ntawm neural regeneration. Cov kev sim tsiaj tau pom tias Melanotan 2 hmoov tuaj yeem txhawb kev tsim kho thiab kho cov hlab ntsha peripheral. Piv txwv li, nyob rau hauv tus nas sciatic paj hlwb raug mob qauv, Melanotan 2 ho txhim kho qhov zoo ntawm kev hnov lus muaj nuj nqi, tshwj xeeb tshaj yog ntawm cov koob tshuaj tshwj xeeb (xws li 20 μ g / kg / 48h). Cov nyhuv no yuav muaj feem xyuam rau kev txhawb nqa ntawm neuronal ciaj sia, axonal kev loj hlob, thiab synapse tsim los ntawm Melanotan 2. Cov kev tswj xyuas cov nyhuv ntawm Melanotan 2 ntawm kev sib deev muaj nuj nqi yog lwm qhov tseem ceeb ntawm daim ntawv thov. Kev tshawb fawb tau pom tias Melanotan 2 tuaj yeem txhim kho kev sib deev muaj siab thiab arousal los ntawm activating MC3R thiab MC4R receptors. Hauv cov txiv neej uas muaj erectile kawg (ED), Melanotan 2 tau pom tias yog ib qho kev txhawb nqa erectile, muaj peev xwm txhawb nqa erection los ntawm koob tshuaj - nyob ntawm induction. Cov nyhuv no yuav muaj feem xyuam rau Melanotan 2 txhawb cov leeg nqaij so hauv lub cev corpus cavernosum thiab ua rau cov ntshav ntws mus rau hauv siab.
Daim ntawv thov nyob rau hauv pem hauv ntej ntawm neural tswj
Erectile kawg yog ib qho ntawm kev sib deev tsis ua haujlwm hauv cov txiv neej, uas cuam tshuam rau lub neej zoo ntawm cov neeg mob. Melanotan 2 tuaj yeem txhim kho erectile kawg los ntawm kev ua kom MC receptors, tshwj xeeb tshaj yog MC4R receptors. Cov kev sim tsiaj tau pom tias kev txhaj tshuaj ntawm Melanotan 2 (xws li 1 mg / kg) ua rau muaj txiaj ntsig zoo rau erectile teb los ntawm cavernous paj stimulation. Tsis tas li ntawd, Melanotan 2 tuaj yeem txo lub sijhawm latency ntawm thawj erection tshwm sim, nce qhov zaus thiab lub sijhawm ntawm erections. Kev tswj hwm cov nyhuv ntawm Melanotan 2 ntawm kev noj qab haus huv thiab lub zog sib npaug kuj yog ib qho ntawm nws cov haujlwm tseem ceeb ntawm lub cev. Kev tshawb fawb tau pom tias Melanotan 2 tuaj yeem txo lub cev hnyav los ntawm kev ua kom MC4R receptors, suppressing qab los noj mov, thiab txo cov khoom noj. Nyob rau hauv tus qauv nas, Melanotan 2 kuj induced thermogenic cov tshuaj tiv thaiv thiab ntxiv zog siv. Cov nyhuv no yuav cuam tshuam rau Melanotan 2 tswj cov kev cai hypothalamic qab los noj mov thiab txhawb kev rog rog.
Ntau qhov kev sim tsiaj tau pom tias Melanotan 2 muaj qhov cuam tshuam tseem ceeb hauv kev tswj hwm neural. Piv txwv li, nyob rau hauv tus nas sciatic paj hlwb raug mob qauv, Melanotan 2 ho txhim kho qhov zoo ntawm kev hnov qab muaj nuj nqi. Tsis tas li ntawd, Melanotan 2 tau qhia txog kev kho mob zoo hauv cov tsiaj ua qauv ntawm erectile kawg. Cov pov thawj kev sim no muab kev txhawb zog rau kev thov ntawm Melanotan 2 hauv kev tswj hwm neural. Txawm hais tias Melanotan 2 tsis tau txais kev pom zoo rau tib neeg kev kho mob hauv ntau lub tebchaws thiab cheeb tsam, qee qhov kev sim tshuaj tau tshawb nrhiav nws cov peev txheej hauv kev tswj hwm neural. Piv txwv li, hauv cov neeg mob uas muaj erectile kawg, Melanotan 2 tau pom tias yuav txhim kho erectile muaj nuj nqi thiab txhim kho lub neej kev sib deev. Txawm li cas los xij, vim qhov kev ntsuam xyuas tsis txaus ntawm kev nyab xeeb thiab ntev - lub sij hawm ua tau zoo ntawm Melanotan 2, nws daim ntawv thov kev kho mob tseem yuav tsum tau ceev faj.
Cim npe nrov: Melanotan 2 Powder CAS 121062-08-6, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom