Pumpkin Noob Peptide

1. Anti ce qaug zog
Txoj kev tshawb no luam tawm los ntawm Dan Yi et al. (2026) nyob rau hauv Phau ntawv Journal of Food Industry Technology systematically ntsuam xyuas cov nyhuv anti qaug zog ntawm taub dag noob. Lub sijhawm ua luam dej ntawm nas nyob rau hauv siab - pawg koob tshuaj tau ntev heev (P<0.05); The levels of muscle glycogen and liver glycogen significantly increased (P<0.05); The levels of serum urea nitrogen (BUN), lactate (LA), and lactate dehydrogenase (LDH) were significantly reduced (P<0.05); The activities of antioxidant enzymes such as SOD, GSH Px, CAT were significantly increased (P<0.05), while MDA was significantly decreased (P<0.05).

Cov koob tshuaj - teb kev sib raug zoo yog qhov tseeb, nrog rau siab - pab pawg koob tshuaj ua tau zoo tshaj qhov nruab nrab thiab qis - cov pab pawg hauv cov ntsuas feem ntau, qhia tias nws tawm tsam kev tawm dag zog- ua rau qaug zog los ntawm kev ntxiv dag zog rau kev tiv thaiv antioxidant thiab ua kom tshem tawm cov khoom pov tseg hauv metabolic.

Cov txiaj ntsig kev sim qhia tau hais tias:
Piv nrog rau pawg qauv, lub sijhawm ua luam dej ntawm nas nyob rau hauv siab - pawg koob tshuaj tau ntev heev (P<0.05);
Cov qib ntawm cov leeg glycogen thiab daim siab glycogen nce ntxiv (P<0.05), providing the body with more abundant energy reserves;

Cov qib ntawm serum urea nitrogen (BUN), lactate (LA), thiab lactate dehydrogenase (LDH) tau txo qis (P<0.05), indicating a significant improvement in the efficiency of metabolic waste removal;
Cov enzymes antioxidant SOD, GSH Px, thiab CAT tau nce ntau hauv cov ntshav thiab daim siab (P<0.05), while the lipid peroxidation product MDA was significantly decreased (P<0.05), indicating that pumpkin seed counteract exercise induced oxidative damage by strengthening the antioxidant defense system.
Kev txhim kho nyob rau hauv cov lus qhia saum toj no ntawm qib siab - pawg koob tshuaj tau zoo dua li ntawm pawg tshuaj qis thiab nruab nrab (tshwj tsis yog rau daim siab glycogen thiab LDH), uas qhia meej meej koob- teb kev sib raug zoo. Txoj kev tshawb no muab lub hauv paus zoo theoretical rau kev siv cov noob taub dag hauv kev tswj kev ua kis las.

2. Txo cov ntshav siab - lub hom phiaj meej ntawm ACE inhibitory peptides
Pab neeg tshawb fawb coj los ntawm He Haiyan et al. (2022) los ntawm Northeast Forestry University tau luam tawm ib qho kev kawm tseem ceeb hauv Food Science. Nine ACE inhibitory peptides tau txheeb xyuas los ntawm cov khoom qis dua 1 kDa siv HPLC/Q-TOF-MS/MS: LLV, LVF, LTPL, SVLF, LLPQ, MLPL, LLPGF, VLLPE, thiab RFLLL, tag nrho cov no yog cov kab ke tshiab. Ntawm lawv, IC50 qhov tseem ceeb ntawm LLPGF (IC ₅₀=0.48 mmol/L), MLPL (IC ₅₀=0.36 mmol/L), LVF (IC ₅₀=0.17 mmol/L), thiab RFPLL (IC ₅₀} mmol/L) tag nrho yog qis dua.

3. Antioxidant thiab anti-inflammatory - multi- phiaj xwm kev tiv thaiv
Nws muaj ntau cov tshuaj tiv thaiv antioxidant muaj feem xyuam rau cov amino acids (xws li glutamic acid, proline, thiab lwm yam) thiab ua haujlwm sib koom ua ke nrog cov khoom xyaw nquag xws li vitamin E (tsuas yog gamma tocopherol), carotenoids, thiab cog sterols hauv cov noob taub dag. Kev tshawb fawb tau pom tias nws tuaj yeem txhim kho kev ua haujlwm ntawm endogenous antioxidant enzymes xws li SOD, GSH Px, CAT, thaum txo oxidative kev puas tsuaj cov cim xws li MDA. Nws nthuav tawm kev ua haujlwm zoo hauv kev tshem tawm cov dawb radicals thiab ncua kev laus ntawm tes. Tsis tas li ntawd, nws lub peev xwm los inhibit inflammatory mediators xws li prostaglandins ua rau nws muaj txiaj ntsig zoo rau kev tswj xyuas cov kab mob ntev.

4. Antioxidant thiab Cellular tiv thaiv
Txoj kev tshawb no los ntawm Li Quanhong et al. (2025) pom tias nyob rau hauv qhov concentration ntawm 1-40 mg / mL,Pumpkin noob peptidespom qhov koob tshuaj tseem ceeb-kev sib raug zoo nrog DPPH radical scavenging tus nqi nce ntawm 28.80% mus rau 91.62%, ABTS scavenging tus nqi nce los ntawm 16.95% mus rau 83.55%, thiab FRAP tus nqi nce ntawm 0.14 mus rau 0.83 μ mol / ml. Siv H ₂ O ₂ - induced oxidative kev puas tsuaj qauv hauv Caco-2 hlwb, antioxidant peptides tuaj yeem tiv thaiv cov hlwb los ntawm kev puas tsuaj oxidative kev nyuaj siab, nce SOD enzyme kev ua haujlwm thiab GSH cov ntsiab lus, thiab tshem tawm cov pa oxygen ntau dhau hauv cov hlwb.

5. Kev tiv thaiv kev laus thiab kev tiv thaiv tawv nqaij
Wang Peiyu (Jiangnan University) tus master's thesis yog thawj zaug los tshuaj xyuas qhov kev tiv thaiv - kev laus ntawm cov noob taub dag ntawm qib cellular. Cov peptide tau los ntawm alkaline trypsin hydrolysis ua rau muaj kev loj hlob ntawm 113.1% rau HSF hlwb thiab 114.87% rau HaCaT hlwb; Cov ntsiab lus ntawm intracellular collagen tau nce 18.07%, elastin cov ntsiab lus nce 39.09%, thiab cov ntsiab lus hyaluronic acid nce 40.69%. Tom qab ntau-pab kom huv los ntawm ultrafiltration, Sephadex G-10, DEAE-52, thiab RP-HPLC, tau txais cov khoom nquag PU-3-B-2-I, thiab ob qhov tshiab peptide sequences tau txheeb xyuas: Lnddll (Leu Asn Asp Asp Vallev Leu) thiab G. HSF thiab HaCaT cell proliferation ntawm 139.06% thiab 131.31%, feem.

6. Txhim kho kev pw tsaug zog
Muaj nplua nuj nyob rau hauv tryptophan, nws yog ib tug precursor tshuaj rau synthesis ntawm serotonin thiab melatonin. Cov noob taub dag tau yooj yim absorbed los ntawm tib neeg lub cev nyob rau hauv daim ntawv ntawm me me molecule peptides thaum khaws tryptophan. Qhov pom zoo noj txhua hnub ntawm cov extract yog 500-1000mg, thiab kev siv tas li rau 2-3 lub hlis muaj cov teebmeem tseem ceeb. Nws tuaj yeem siv los ua kev kho mob rau insomnia.

7. Kev tiv thaiv kab mob parasitic
Pumpkin noob extract tau ib txwm siv los tshem tawm cov kab mob hauv plab xws li tapeworms thiab roundworms.

Inheriting no ib txwm ua tau zoo thiab pab raws li ib tug adjuvant kev kho mob rau cov kab mob parasitic.

8. Kev tswj kev tiv thaiv kab mob thiab tiv thaiv- qog muaj peev xwm
Kev tshawb fawb tau pom tias ribosome inactivating protein (RIP) hu ua Moschatin tau raug cais tawm ntawm cov noob taub dag, nrog IC ₅₀ ntawm tsuas yog 0.04 nM tiv thaiv tib neeg melanoma cell kab M21, uas yog 1500 npaug qis dua li cov koob tshuaj dawb Moschatin. Thaum siv rau hauv daim ntawv ntawm Moschatin-Ng76 immunotoxin, nws tuaj yeem cuam tshuam kev loj hlob ntawm cov qog qog hlwb. Tsis tas li ntawd, cov tshuaj bioactive hauv cov noob taub dag tau raug pov thawj tias muaj ntau yam tshuaj siv tshuaj xws li tshuaj tiv thaiv- qog thiab tiv thaiv cell.

1. Cov dej haus thiab cov dej haus ua si
Pumpkin noob peptidesyog soluble tag nrho hauv dej, nrog kev ruaj ntseg zoo (acid thiab kub tsis kam, solubility tsis cuam tshuam), cov ntsiab lus tsis muaj amino acids, thiab siab purity. Nws raug nquahu kom ntxiv 0.5% mus rau 2% hauv cov dej haus xws li cov kua mis thiab cov dej haus ua si, thiab 0.1% mus rau 5% hauv cov dej haus xws li mis nyuj, yogurt, thiab kua txiv hmab txiv ntoo. Nws cov khoom tiv thaiv kev qaug zog ua rau nws tshwj xeeb tshaj yog tsim rau kev tsim cov khoom noj khoom haus kis las.
2. Kev lom zem thiab ci khoom

Ntxiv 3% mus rau 5% hauv cov khoom lag luam thiab cov khoom ci tuaj yeem muab siab -cov amino acids zoo thiab cov kab mob, txhim kho cov khoom noj muaj txiaj ntsig zoo.

3. Noj qab haus huv
Qhov nyiaj ntxiv tuaj yeem ncav cuag 10% mus rau 50% (raws li cov kev cai tswjfwm), siv rau cov khoom noj noj qab haus huv xws li cov khoom noj khoom haus rau cov neeg laus thiab cov laus, cov hlab plawv, thiab cov tshuaj antioxidants.
4. Cov khoom noj nqaij thiab seasoning
Nws tuaj yeem siv los ua cov khoom noj khoom haus ntxiv dag zog hauv kev tsim cov khoom noj nqaij thiab seasonings, txhim kho cov amino acid muaj pes tsawg leeg thiab tsw ntawm cov khoom.